To infinity and beyond: Strategies for fabricating medicines in outer space

[1]  Pedro Cabalar,et al.  Accelerating 3D printing of pharmaceutical products using machine learning , 2022, International journal of pharmaceutics: X.

[2]  V. Hessel,et al.  Astropharmacy: Pushing the boundaries of the pharmacists' role for sustainable space exploration. , 2022, Research in social & administrative pharmacy : RSAP.

[3]  Glenn Hole,et al.  Digitalization in pharmaceutical industry: What to focus on under the digital implementation process? , 2021, International journal of pharmaceutics: X.

[4]  A. Basit,et al.  Smartphone-enabled 3D printing of medicines. , 2021, International journal of pharmaceutics.

[5]  C. Calvache,et al.  Key points for the development of antioxidant cocktails to prevent cellular stress and damage caused by reactive oxygen species (ROS) during manned space missions , 2021, NPJ microgravity.

[6]  Sarah J Trenfield,et al.  Connected Healthcare: Improving Patient Care using Digital Health Technologies. , 2021, Advanced drug delivery reviews.

[7]  F. Otero-Espinar,et al.  Fighting type 2 diabetes: Formulation strategies for peptide-based therapeutics , 2021, Acta pharmaceutica Sinica. B.

[8]  J. Greenberger,et al.  Space Radiation Protection Countermeasures in Microgravity and Planetary Exploration , 2021, Life.

[9]  Pedro Cabalar,et al.  Machine learning applied to over 900 3D printed drug delivery systems. , 2021, Journal of controlled release : official journal of the Controlled Release Society.

[10]  Y. S. Zhang,et al.  A Smartphone‐Enabled Portable Digital Light Processing 3D Printer , 2021, Advanced materials.

[11]  Z. Ahmad,et al.  A Review of Emerging Technologies Enabling Improved Solid Oral Dosage Form Manufacturing and Processing. , 2021, Advanced drug delivery reviews.

[12]  A. Basit,et al.  Harnessing Artificial Intelligence for the Next Generation of 3D Printed Medicines. , 2021, Advanced drug delivery reviews.

[13]  Sarah J Trenfield,et al.  Translating 3D printed pharmaceuticals: from hype to real-world clinical applications. , 2021, Advanced drug delivery reviews.

[14]  Y. S. Zhang,et al.  Programmable microbial ink for 3D printing of living materials produced from genetically engineered protein nanofibers , 2021, Nature Communications.

[15]  Lawrence X. Yu,et al.  Industry 4.0 for Pharmaceutical Manufacturing: Preparing for the Smart Factories of the Future. , 2021, International journal of pharmaceutics.

[16]  H. Alper,et al.  Applications, challenges, and needs for employing synthetic biology beyond the lab , 2021, Nature Communications.

[17]  A. Basit,et al.  Semi-solid extrusion 3D printing in drug delivery and biomedicine: Personalised solutions for healthcare challenges. , 2021, Journal of controlled release : official journal of the Controlled Release Society.

[18]  T. Voigtmann,et al.  A gravity-independent powder-based additive manufacturing process tailored for space applications , 2021, Additive Manufacturing.

[19]  K. Gordon,et al.  Potential of Raman Spectroscopy in Facilitating Pharmaceutical Formulations DevelopmPotential of Raman Spectroscopy in Facilitating Pharmaceutical Formulations Development - An AI perspective. , 2021, International journal of pharmaceutics.

[20]  S. L. Mayo,et al.  Microbiome for Mars: surveying microbiome connections to healthcare with implications for long-duration human spaceflight, virtual workshop, July 13, 2020 , 2021, Microbiome.

[21]  Sarah J Trenfield,et al.  Stereolithography (SLA) 3D printing of a bladder device for intravesical drug delivery. , 2021, Materials science & engineering. C, Materials for biological applications.

[22]  F. Otero-Espinar,et al.  3D Printed Tacrolimus Rectal Formulations Ameliorate Colitis in an Experimental Animal Model of Inflammatory Bowel Disease , 2020, Biomedicines.

[23]  D. Kelly,et al.  Xolography for linear volumetric 3D printing , 2020, Nature.

[24]  Roger L. Chang,et al.  Engineering Radioprotective Human Cells Using the Tardigrade Damage Suppressor Protein, DSUP , 2020 .

[25]  Scott M Smith,et al.  Red risks for a journey to the red planet: The highest priority human health risks for a mission to Mars , 2020, NPJ microgravity.

[26]  A. Cheremisin,et al.  On the possibility of growing vegetables and fruits on the lunar base , 2020, IOP Conference Series: Earth and Environmental Science.

[27]  K. Binsted,et al.  Autonomous Psychological Support for Isolation and Confinement. , 2020, Aerospace medicine and human performance.

[28]  Mathias Basner,et al.  Fundamental Biological Features of Spaceflight: Advancing the Field to Enable Deep-Space Exploration , 2020, Cell.

[29]  Pamela Robles Martinez,et al.  Vat photopolymerization 3D printing for advanced drug delivery and medical device applications. , 2020, Journal of controlled release : official journal of the Controlled Release Society.

[30]  Francine E. Garrett-Bakelman,et al.  Multi-omic, Single-Cell, and Biochemical Profiles of Astronauts Guide Pharmacological Strategies for Returning to Gravity , 2020, Cell reports.

[31]  Pedro Cabalar,et al.  M3DISEEN: A Novel Machine Learning Approach for Predicting the 3D Printability of Medicines. , 2020, International journal of pharmaceutics.

[32]  Yu-Zhong Wang,et al.  4D printing of shape memory aliphatic copolyester via UV-assisted FDM strategy for medical protective devices , 2020 .

[33]  S. Turroni,et al.  Gut Microbiome and Space Travelers’ Health: State of the Art and Possible Pro/Prebiotic Strategies for Long-Term Space Missions , 2020, Frontiers in Physiology.

[34]  L. E. Warren,et al.  Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight , 2020, Proceedings of the National Academy of Sciences.

[35]  L. De Gennaro,et al.  Sleep in Isolated, Confined, and Extreme (ICE): A Review on the Different Factors Affecting Human Sleep in ICE , 2020, Frontiers in Neuroscience.

[36]  Francine E. Garrett-Bakelman,et al.  Temporal Telomere and DNA Damage Responses in the Space Radiation Environment. , 2020, Cell reports.

[37]  S. Orimo,et al.  Investigation of shielding material properties for effective space radiation protection. , 2020, Life sciences in space research.

[38]  Longjian Xue,et al.  Assisted 3D printing of microneedle patches for minimally invasive glucose control in diabetes. , 2020, Materials science & engineering. C, Materials for biological applications.

[39]  Abdul W. Basit,et al.  3D printed tacrolimus suppositories for the treatment of ulcerative colitis , 2020, Asian journal of pharmaceutical sciences.

[40]  M. Wasielewski,et al.  Selenomelanin: An Abiotic Selenium Analogue of Pheomelanin. , 2020, Journal of the American Chemical Society.

[41]  P. Chilibeck,et al.  Nutritional interventions during bed rest and spaceflight: prevention of muscle mass and strength loss, bone resorption, glucose intolerance, and cardiovascular problems. , 2020, Nutrition research.

[42]  Alicia M. Ortega,et al.  Inhibition of myostatin prevents microgravity-induced loss of skeletal muscle mass and strength , 2020, PloS one.

[43]  H. Pataki,et al.  End-to-End Continuous Manufacturing of Conventional Compressed Tablets: from Flow Synthesis to Tableting through Integrated Crystallization and Filtration. , 2020, International journal of pharmaceutics.

[44]  Sara Eyal,et al.  How do the pharmacokinetics of drugs change in astronauts in space? , 2020, Expert opinion on drug metabolism & toxicology.

[45]  C. Moser,et al.  High-resolution tomographic volumetric additive manufacturing , 2020, Nature Communications.

[46]  T. Brunstetter,et al.  Spaceflight associated neuro-ocular syndrome (SANS) and the neuro-ophthalmologic effects of microgravity: a review and an update , 2020, npj Microgravity.

[47]  Bhesh Bhandari,et al.  Incorporation of probiotics (Bifidobacterium animalis subsp. Lactis) into 3D printed mashed potatoes: Effects of variables on the viability. , 2020, Food research international.

[48]  Abdul W. Basit,et al.  Non-destructive dose verification of two drugs within 3D printed polyprintlets. , 2020, International journal of pharmaceutics.

[49]  D. Texier,et al.  From new space to big space: How commercial space dream is becoming a reality , 2020, Acta Astronautica.

[50]  D. Fatouros,et al.  Development of Bio-Active Patches Based on Pectin for the Treatment of Ulcers and Wounds Using 3D-Bioprinting Technology , 2020, Pharmaceutics.

[51]  R. Qaisar,et al.  Muscle unloading: A comparison between spaceflight and ground‐based models , 2019, Acta physiologica.

[52]  A. Ozer,et al.  Ionizing radiation and its effects on pharmaceuticals , 2019, Journal of Radioanalytical and Nuclear Chemistry.

[53]  L. Rothschild,et al.  A Makerspace for Life Support Systems in Space. , 2019, Trends in biotechnology.

[54]  Scott M Smith,et al.  Resistive exercise in astronauts on prolonged spaceflights provides partial protection against spaceflight-induced bone loss. , 2019, Bone.

[55]  Carrie Arnold,et al.  Who shrank the drug factory? Briefcase-sized labs could transform medicine , 2019, Nature.

[56]  Michinao Hashimoto,et al.  Chocolate-based Ink Three-dimensional Printing (Ci3DP) , 2019, Scientific Reports.

[57]  A. Zocca,et al.  Enabling the 3D Printing of Metal Components in µ‐Gravity , 2019, Advanced Materials Technologies.

[58]  Nasa,et al.  Dietary Formulas Fortify Antioxidant Supplements , 2019 .

[59]  Liz Fletcher,et al.  Future Trends in Synthetic Biology—A Report , 2019, Front. Bioeng. Biotechnol..

[60]  P. G. Campbell,et al.  3D bioprinting of collagen to rebuild components of the human heart , 2019, Science.

[61]  D. Pierson,et al.  Study of the impact of long-duration space missions at the International Space Station on the astronaut microbiome , 2019, Scientific Reports.

[62]  J. Agui,et al.  Preparing for planetary surface exploration by measuring habitat dust intrusion with filter tests during an analogue Mars mission , 2019, Acta Astronautica.

[63]  Rebecca S. Blue,et al.  Supplying a pharmacy for NASA exploration spaceflight: challenges and current understanding , 2019, npj Microgravity.

[64]  Rebecca S. Blue,et al.  Limitations in predicting radiation-induced pharmaceutical instability during long-duration spaceflight , 2019, npj Microgravity.

[65]  Suzanne T. Bell,et al.  What We Know About Team Dynamics for Long-Distance Space Missions: A Systematic Review of Analog Research , 2019, Front. Psychol..

[66]  Francine E. Garrett-Bakelman,et al.  The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight , 2019, Science.

[67]  P. Armenante,et al.  STERILIZATION PROCESSES IN THE PHARMACEUTICAL INDUSTRY , 2019, Chemical Engineering in the Pharmaceutical Industry.

[68]  Sungshin Y. Choi,et al.  Behavior of mice aboard the International Space Station , 2019, Scientific Reports.

[69]  Jason M. Wood,et al.  Characterization of the total and viable bacterial and fungal communities associated with the International Space Station surfaces , 2019, Microbiome.

[70]  Simon Gaisford,et al.  3D Printed Pellets (Miniprintlets): A Novel, Multi-Drug, Controlled Release Platform Technology , 2019, Pharmaceutics.

[71]  E. Olson,et al.  The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3 , 2019, Science.

[72]  Kyle W. Binder,et al.  In Situ Bioprinting of Autologous Skin Cells Accelerates Wound Healing of Extensive Excisional Full-Thickness Wounds , 2019, Scientific Reports.

[73]  R. Reiter,et al.  Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis , 2019, Frontiers in Neuroendocrinology.

[74]  Leroy Cronin,et al.  Organic synthesis in a modular robotic system driven by a chemical programming language , 2019, Science.

[75]  Mark A. Burns,et al.  Rapid, continuous additive manufacturing by volumetric polymerization inhibition patterning , 2019, Science Advances.

[76]  P. Suedfeld.  Antarctica and space as psychosocial analogues , 2018, REACH.

[77]  Rong Zhang,et al.  Lower body negative pressure to safely reduce intracranial pressure , 2018, The Journal of physiology.

[78]  A. Jonker,et al.  Recommendations for the design of small population clinical trials , 2018, Orphanet Journal of Rare Diseases.

[79]  Niki Werkheiser,et al.  3D Printing in Zero G Technology Demonstration Mission: complete experimental results and summary of related material modeling efforts , 2018, The International journal, advanced manufacturing technology.

[80]  Scott M Smith,et al.  Spaceflight-related ocular changes: the potential role of genetics, and the potential of B vitamins as a countermeasure , 2018, Current opinion in clinical nutrition and metabolic care.

[81]  F. Naef,et al.  Cross-regulatory circuits linking inflammation, high-fat diet, and the circadian clock , 2018, Genes & development.

[82]  Jukka Rantanen,et al.  Analytical aspects of printed oral dosage forms , 2018, International journal of pharmaceutics.

[83]  Simon Gaisford,et al.  3D printed drug products: Non‐destructive dose verification using a rapid point‐and‐shoot approach , 2018, International journal of pharmaceutics.

[84]  H. Ishida,et al.  Development of Hydrogen-Rich Benzoxazine Resins with Low Polymerization Temperature for Space Radiation Shielding , 2018, ACS omega.

[85]  Che J. Connon,et al.  3D bioprinting of a corneal stroma equivalent , 2018, Experimental eye research.

[86]  Shen Ning,et al.  Addressing Unmet Clinical Needs with 3D Printing Technologies , 2018, Advanced healthcare materials.

[87]  G. Rao,et al.  Point-of-care production of therapeutic proteins of good-manufacturing-practice quality , 2018, Nature Biomedical Engineering.

[88]  Michael C. McAlpine,et al.  3D Printed Functional and Biological Materials on Moving Freeform Surfaces , 2018, Advanced materials.

[89]  Dong Liu,et al.  On-orbit sleep problems of astronauts and countermeasures , 2018, Military Medical Research.

[90]  R. Finkel,et al.  A checklist for clinical trials in rare disease: obstacles and anticipatory actions—lessons learned from the FOR-DMD trial , 2018, Trials.

[91]  L. C. Taylor,et al.  Physiological and Functional Alterations after Spaceflight and Bed Rest , 2018, Medicine and science in sports and exercise.

[92]  Dennis Douroumis,et al.  3D printed microneedles for insulin skin delivery , 2018, International journal of pharmaceutics.

[93]  R. Hughson,et al.  Heart in space: effect of the extraterrestrial environment on the cardiovascular system , 2018, Nature Reviews Cardiology.

[94]  Wei Zhu,et al.  3D-Printing of Functional Biomedical Microdevices via Light- and Extrusion-Based Approaches. , 2018, Small methods.

[95]  D. Green,et al.  Spinal Health during Unloading and Reloading Associated with Spaceflight , 2018, Front. Physiol..

[96]  P. Hodkinson,et al.  An overview of space medicine. , 2017, British journal of anaesthesia.

[97]  Rebecca S. Blue,et al.  Commercial spaceflight: Progress and challenges in expanding human access to space , 2017 .

[98]  Hartmut Derendorf,et al.  Drugs in space: Pharmacokinetics and pharmacodynamics in astronauts. , 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[99]  Eric Friedman,et al.  A Psychiatric Formulary for Long-Duration Spaceflight. , 2017, Aerospace medicine and human performance.

[100]  H. Selker,et al.  Changing the incentives for development of low-cost high-impact treatments , 2017, Journal of Clinical and Translational Science.

[101]  P. Mehta,et al.  Impact of space environment on stability of medicines: Challenges and prospects , 2017, Journal of pharmaceutical and biomedical analysis.

[102]  B. Levine,et al.  Effect of gravity and microgravity on intracranial pressure , 2017, The Journal of physiology.

[103]  J. Rantanen,et al.  Visualization and Non-Destructive Quantification of Inkjet-Printed Pharmaceuticals on Different Substrates Using Raman Spectroscopy and Raman Chemical Imaging , 2017, Pharmaceutical Research.

[104]  Kelley J. Slack,et al.  Selecting astronauts for long-duration exploration missions: Considerations for team performance and functioning , 2017 .

[105]  Léa J Pourchet,et al.  Human Skin 3D Bioprinting Using Scaffold‐Free Approach , 2017, Advanced healthcare materials.

[106]  C. Guy,et al.  Gardening for Therapeutic People-Plant Interactions during Long-Duration Space Missions , 2017 .

[107]  Hannah C. Slater,et al.  Oral, ultra–long-lasting drug delivery: Application toward malaria elimination goals , 2016, Science Translational Medicine.

[108]  N. Kerr,et al.  Simulated Partners and Collaborative Exercise (SPACE) to boost motivation for astronauts: study protocol , 2016, BMC psychology.

[109]  H. Lorenzi,et al.  The Challenge of Maintaining a Healthy Microbiome during Long-Duration Space Missions , 2016, Frontiers in Astronomy and Space Sciences.

[110]  Alamelu Sundaresan,et al.  The impact of microgravity on bone in humans. , 2016, Bone.

[111]  M. Iqbal,et al.  Gamma – irradiation induced degradation of diclofenac in aqueous solution: Kinetics, role of reactive species and influence of natural water parameters , 2016 .

[112]  S. Y. Wong,et al.  On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system , 2016, Science.

[113]  A. Choukér,et al.  Effects of isolation and confinement on humans-implications for manned space explorations. , 2016, Journal of applied physiology.

[114]  Pablo Carbonell,et al.  Synthetic biology for pharmaceutical drug discovery , 2015, Drug design, development and therapy.

[115]  Martina Heer,et al.  Bone metabolism and renal stone risk during International Space Station missions. , 2015, Bone.

[116]  A. Archakov,et al.  Spaceflight Effects on Cytochrome P450 Content in Mouse Liver , 2015, PloS one.

[117]  G. Hartmann,et al.  Where Failure Is Not an Option –Personalized Medicine in Astronauts , 2015, PloS one.

[118]  Shlomo Wagner,et al.  The effects of acute social isolation on long-term social recognition memory , 2015, Neurobiology of Learning and Memory.

[119]  V. Wotring,et al.  Medication use by U.S. crewmembers on the International Space Station , 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[120]  Jukka Rantanen,et al.  Raman spectroscopy in pharmaceutical product design. , 2015, Advanced drug delivery reviews.

[121]  R. C. Richter,et al.  The Zero Gravity Mass Measurement Device , 2015 .

[122]  A. Basit,et al.  Fused-filament 3D printing (3DP) for fabrication of tablets. , 2014, International journal of pharmaceutics.

[123]  Chetan Shende,et al.  Drug Stability Analysis by Raman Spectroscopy , 2014, Pharmaceutics.

[124]  Niki Werkheiser,et al.  Overview of NASA Initiatives in 3D Printing and Additive Manufacturing , 2014 .

[125]  Scott M Smith,et al.  Nutritional biochemistry of spaceflight. , 2014, Advances in clinical chemistry.

[126]  Özlem Türeci,et al.  mRNA-based therapeutics — developing a new class of drugs , 2014, Nature Reviews Drug Discovery.

[127]  C. Czeisler,et al.  Prevalence of sleep deficiency and use of hypnotic drugs in astronauts before, during, and after spaceflight: an observational study , 2014, The Lancet Neurology.

[128]  Andrew Owens,et al.  An Independent Assessment of the Technical Feasibility of the Mars One Mission Plan , 2014 .

[129]  Anthony Atala,et al.  3D bioprinting of tissues and organs , 2014, Nature Biotechnology.

[130]  Clarence Sams,et al.  Terrestrial stress analogs for spaceflight associated immune system dysregulation , 2014, Brain, Behavior, and Immunity.

[131]  Francis A. Cucinotta,et al.  Space radiation risks to the central nervous system , 2014 .

[132]  Mallory M. Johnston,et al.  The Road to Realizing In-Space Manufacturing , 2014 .

[133]  Millennia Foy,et al.  Relationship Between Carbon Dioxide Levels and Reported Headaches on the International Space Station , 2014, Journal of occupational and environmental medicine.

[134]  S. Feldon,et al.  Effect of acetazolamide on visual function in patients with idiopathic intracranial hypertension and mild visual loss: the idiopathic intracranial hypertension treatment trial. , 2014, JAMA.

[135]  Adrian J. Ecker,et al.  Psychological and Behavioral Changes during Confinement in a 520-Day Simulated Interplanetary Mission to Mars , 2014, PloS one.

[136]  D. Kaplan,et al.  Stability of Silk and Collagen Protein Materials in Space , 2013, Scientific Reports.

[137]  Francis A. Cucinotta,et al.  How Safe Is Safe Enough? Radiation Risk for a Human Mission to Mars , 2013, PloS one.

[138]  K. Mealey,et al.  Clinical pharmacology and therapeutics. , 2013, The Veterinary clinics of North America. Small animal practice.

[139]  Edouard I Azzam,et al.  Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury. , 2012, Cancer letters.

[140]  Scott M Smith,et al.  Benefits for bone from resistance exercise and nutrition in long‐duration spaceflight: Evidence from biochemistry and densitometry , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[141]  Jeremy R. Athy,et al.  Modafinil as a replacement for dextroamphetamine for sustaining alertness in military helicopter pilots. , 2012, Aviation, space, and environmental medicine.

[142]  D. Dinges,et al.  Validity and Sensitivity of a Brief Psychomotor Vigilance Test (PVT-B) to Total and Partial Sleep Deprivation. , 2011, Acta astronautica.

[143]  L. Putcha,et al.  Stability of vitamin B complex in multivitamin and multimineral supplement tablets after space flight. , 2011, Journal of pharmaceutical and biomedical analysis.

[144]  E. Kempner.  Direct Effects of Ionizing Radiation on Macromolecules. , 2011, Journal of polymer science. Part B, Polymer physics.

[145]  Lakshmi Putcha,et al.  Evaluation of Physical and Chemical Changes in Pharmaceuticals Flown on Space Missions , 2011, The AAPS Journal.

[146]  Peter Kleinebudde,et al.  Investigating the relationship between drug distribution in solid lipid matrices and dissolution behaviour using Raman spectroscopy and mapping. , 2010, Journal of pharmaceutical sciences.

[147]  Clemens Schulze-Briese,et al.  Origin and temperature dependence of radiation damage in biological samples at cryogenic temperatures , 2009, Proceedings of the National Academy of Sciences.

[148]  L. Braby,et al.  Assessment of nutrient stability in foods from the space food system after long-duration spaceflight on the ISS. , 2009, Journal of food science.

[149]  Leif E. Peterson,et al.  NASA Study of Cataract in Astronauts (NASCA). Report 1: Cross-Sectional Study of the Relationship of Exposure to Space Radiation and Risk of Lens Opacity , 2009, Radiation research.

[150]  S. Kondratenko,et al.  Pharmacokinetics of acetaminophen administered in tablets and capsules under long-term space flight conditions , 2009, Pharmaceutical Chemistry Journal.

[151]  Deanna L. Wallace,et al.  CREB regulation of nucleus accumbens excitability mediates social isolation–induced behavioral deficits , 2009, Nature Neuroscience.

[152]  A. Casadevall,et al.  Ionizing radiation: how fungi cope, adapt, and exploit with the help of melanin. , 2008, Current opinion in microbiology.

[153]  Bernard Tilquin,et al.  Cryo-irradiation as a terminal method for the sterilization of drug aqueous solutions. , 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[154]  O. Walton,et al.  Effects of gravity on cohesive behavior of fine powders: implications for processing Lunar regolith , 2007 .

[155]  U. Chinte,et al.  Cryogenic (<20 K) helium cooling mitigates radiation damage to protein crystals. , 2007, Acta Crystallographica Section D: Biological Crystallography.

[156]  C. Schulze-Briese,et al.  Reduction of X-ray-induced radiation damage of macromolecular crystals by data collection at 15 K: a systematic study. , 2007, Acta crystallographica. Section D, Biological crystallography.

[157]  Martina Heer,et al.  Space motion sickness: Incidence, etiology, and countermeasures , 2006, Autonomic Neuroscience.

[158]  Ajaz S Hussain,et al.  Stability profiles of drug products extended beyond labeled expiration dates. , 2006, Journal of pharmaceutical sciences.

[159]  Marco Durante,et al.  Cancer risk from exposure to galactic cosmic rays: implications for space exploration by human beings. , 2006, The Lancet. Oncology.

[160]  J. Biaglow,et al.  Effects of Dietary Supplements on Space Radiation-Induced Oxidative Stress in Sprague-Dawley Rats , 2004, Radiation research.

[161]  E. Schuck,et al.  Physiological, Pharmacokinetic, and Pharmacodynamic Changes in Space , 2004, Journal of clinical pharmacology.

[162]  Guoyao Wu,et al.  Free radicals, antioxidants, and nutrition. , 2002, Nutrition.

[163]  A. Botella,et al.  Sterilization of injectable drugs solutions by irradiation , 2002 .

[164]  F A Cucinotta,et al.  Space Radiation and Cataracts in Astronauts , 2001, Radiation research.

[165]  E. Kempner.  Effects of high-energy electrons and gamma rays directly on protein molecules. , 2001, Journal of pharmaceutical sciences.

[166]  R. Fitts,et al.  Functional and structural adaptations of skeletal muscle to microgravity. , 2001, The Journal of experimental biology.

[167]  G. Przybytniak,et al.  EPR study of free radicals in some drugs γ-irradiated in the solid state , 2000 .

[168]  V. Talrosé,et al.  Radiation resistivity of frozen insulin solutions and suspensions. , 1981, The International journal of applied radiation and isotopes.

[169]  B. Martin.  Manned interplanetary missions , 1964 .

[170]  A. Tappel,et al.  Selenoamino Acids: Decrease of Radiation Damage to Amino Acids and Proteins , 1964, Science.

[171]  Michael Johnson,et al.  Solving the Challenges of Long Duration Space Flight with 3D Printing , 2019 .

[172]  Min Zhang,et al.  Investigation on lemon juice gel as food material for 3D printing and optimization of printing parameters , 2018 .

[173]  Kelli Mars.  The Translational Research Institute for Space Health (TRISH) , 2017 .

[174]  Kelli Mars.  Antarctica Provides ICE to Study Behavior Effects in Astronauts , 2016 .

[175]  J. Harbaugh.  NASA's Centennial Challenges: 3D-Printed Habitat Challenge , 2016 .

[176]  V. Wotring.  Chemical Potency and Degradation Products of Medications Stored Over 550 Earth Days at the International Space Station , 2015, The AAPS Journal.

[177]  I. Plante,et al.  An Assessment of How Radiation Incurred During a Mars Mission Could Affect Food and Pharmaceuticals , 2015 .

[178]  Jeffrey Brief,et al.  Space Food Systems , 2015 .

[179]  Y. Fujii,et al.  Mass measurement of the astronauts on the International Space Station (ISS) for nutritional control , 2012 .

[180]  L. Putcha,et al.  Bioavailability of Promethazine during Spaceflight , 2009 .

[181]  J. Granry,et al.  [Key points.] , 2005, Presse medicale.

[182]  J W Wilson,et al.  Implementation of ALARA radiation protection on the ISS through polyethylene shielding augmentation of the Service Module Crew Quarters. , 2004, Advances in space research : the official journal of the Committee on Space Research.

[183]  S. O. Smolyanina,et al.  Developing a vitamin greenhouse for the life support system of the International Space Station and for future interplanetary missions. , 2004, Advances in space research : the official journal of the Committee on Space Research.

[184]  E Brinckmann,et al.  Experiments with small animals in BIOLAB and EMCS on the International Space Station. , 2002, Advances in space research : the official journal of the Committee on Space Research.

[185]  H. Song,et al.  p‐Aminophenol‐induced liver toxicity: Tentative evidence of a role for acetaminophen , 2001, Journal of biochemical and molecular toxicology.

[186]  F. Cucinotta,et al.  A Comparison of Depth Dependence of Dose and Linear Energy Transfer Spectra in Aluminum and Polyethylene , 2000, Radiation research.

[187]  A I Grigoriev,et al.  Manned interplanetary missions: prospective medical problems. , 1998, Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University.

[188]  B. Houtchens,et al.  Medical-care systems for long-duration space missions. , 1993, Clinical chemistry.