Colorectal Cancer Stage at Diagnosis Before vs During the COVID-19 Pandemic in Italy

Key Points Question Was the COVID-19 pandemic associated with more advanced oncologic stage at presentation for colorectal cancer? Findings This cohort study including 17 938 patients treated for colorectal cancer at 81 Italian centers between 2018 and 2021 showed that patients who underwent surgery for colorectal cancer during the pandemic period had higher odds of diagnoses of late-stage cancer, distant metastasis, and stenotic lesions. Meaning This study suggests that the COVID-19 pandemic was associated with diagnosis of colorectal cancer at a more advanced stage, which could potentially translate to a reduction in survival.

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