Histone deacetylase 1 controls CD4+ T cell trafficking in autoinflammatory diseases.

[1]  Nathan H. Roy,et al.  LFA-1 signals to promote actin polymerization and upstream migration in T cells , 2020, Journal of Cell Science.

[2]  M. Farrar,et al.  NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4+ T Cells , 2020, Frontiers in Immunology.

[3]  B. Engelhardt,et al.  Immune cell trafficking across the blood-brain barrier in the absence and presence of neuroinflammation , 2020, Vascular biology.

[4]  L. Elo,et al.  Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation , 2020, JCI insight.

[5]  B. Engelhardt,et al.  Intercellular Adhesion Molecule-1 (ICAM-1) and ICAM-2 Differentially Contribute to Peripheral Activation and CNS Entry of Autoaggressive Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis , 2020, Frontiers in Immunology.

[6]  R. Holmdahl,et al.  Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis. , 2019, Journal of autoimmunity.

[7]  B. Rossi,et al.  LFA-1 Controls Th1 and Th17 Motility Behavior in the Inflamed Central Nervous System , 2019, Front. Immunol..

[8]  B. Engelhardt,et al.  PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation , 2019, Front. Immunol..

[9]  Chunaram Choudhary,et al.  Functions and mechanisms of non-histone protein acetylation , 2018, Nature Reviews Molecular Cell Biology.

[10]  W. Ellmeier,et al.  Histone deacetylase function in CD4+ T cells , 2018, Nature Reviews Immunology.

[11]  Minsoo Kim,et al.  LFA-1 in T Cell Migration and Differentiation , 2018, Front. Immunol..

[12]  G. Lal,et al.  Blood–brain barrier and its function during inflammation and autoimmunity , 2018, Journal of leukocyte biology.

[13]  T. Korn,et al.  T cell responses in the central nervous system , 2017, Nature Reviews Immunology.

[14]  B. Engelhardt,et al.  The movers and shapers in immune privilege of the CNS , 2017, Nature Immunology.

[15]  H. Lassmann,et al.  Multiple sclerosis: experimental models and reality , 2016, Acta Neuropathologica.

[16]  E. Butcher,et al.  Leukocyte Trafficking to the Small Intestine and Colon. , 2016, Gastroenterology.

[17]  K. Croce,et al.  CD43 Functions as an E-Selectin Ligand for Th17 Cells In Vitro and Is Required for Rolling on the Vascular Endothelium and Th17 Cell Recruitment during Inflammation In Vivo , 2016, The Journal of Immunology.

[18]  Javier Rey-Barroso,et al.  T Lymphocyte Migration: An Action Movie Starring the Actin and Associated Actors , 2015, Front. Immunol..

[19]  B. Engelhardt,et al.  Cell surface levels of endothelial ICAM‐1 influence the transcellular or paracellular T‐cell diapedesis across the blood–brain barrier , 2015, European journal of immunology.

[20]  Adam S. Zeiger,et al.  Probing the biomechanical contribution of the endothelium to lymphocyte migration: diapedesis by the path of least resistance , 2014, Journal of Cell Science.

[21]  Åsa K. Björklund,et al.  Full-length RNA-seq from single cells using Smart-seq2 , 2014, Nature Protocols.

[22]  Cole Trapnell,et al.  TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions , 2013, Genome Biology.

[23]  Britta Engelhardt,et al.  Live cell imaging techniques to study T cell trafficking across the blood-brain barrier in vitro and in vivo , 2013, Fluids and Barriers of the CNS.

[24]  D. Ostanin,et al.  Role of LFA‐1 in the activation and trafficking of T cells: Implications in the induction of chronic colitis , 2012, Inflammatory bowel diseases.

[25]  B. Engelhardt,et al.  Going Against the Tide – How Encephalitogenic T Cells Breach the Blood-Brain Barrier , 2012, Journal of Vascular Research.

[26]  Johannes E. Schindelin,et al.  Fiji: an open-source platform for biological-image analysis , 2012, Nature Methods.

[27]  David R. Kelley,et al.  Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks , 2012, Nature Protocols.

[28]  K. Ley,et al.  Leukocyte ligands for endothelial selectins: specialized glycoconjugates that mediate rolling and signaling under flow. , 2011, Blood.

[29]  B. Hemmer,et al.  Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAE , 2011, The Journal of experimental medicine.

[30]  P. Frenette,et al.  Physiological contribution of CD44 as a ligand for E-Selectin during inflammatory T-cell recruitment. , 2011, The American journal of pathology.

[31]  B. Engelhardt,et al.  Review: Leucocyte–endothelial cell crosstalk at the blood–brain barrier: A prerequisite for successful immune cell entry to the brain , 2011, Neuropathology and applied neurobiology.

[32]  B. Engelhardt,et al.  Differential Roles for Endothelial ICAM-1, ICAM-2, and VCAM-1 in Shear-Resistant T Cell Arrest, Polarization, and Directed Crawling on Blood–Brain Barrier Endothelium , 2010, The Journal of Immunology.

[33]  Cheng Zhu,et al.  Rolling cell adhesion. , 2010, Annual review of cell and developmental biology.

[34]  N. Tubridy,et al.  T cells in multiple sclerosis and experimental autoimmune encephalomyelitis , 2010, Clinical and experimental immunology.

[35]  W. Ellmeier,et al.  Conditional Deletion of Histone Deacetylase 1 in T Cells Leads to Enhanced Airway Inflammation and Increased Th2 Cytokine Production , 2010, The Journal of Immunology.

[36]  C. Carman.  Mechanisms for transcellular diapedesis: probing and pathfinding by `invadosome-like protrusions' , 2009, Journal of Cell Science.

[37]  C. Gleissner,et al.  Glycosylation in immune cell trafficking , 2009, Immunological reviews.

[38]  B. Ruffell,et al.  CD44 and its role in inflammation and inflammatory diseases. , 2009, Inflammation & allergy drug targets.

[39]  R. Ransohoff,et al.  α4 Integrin/FN-CS1 mediated leukocyte adhesion to brain microvascular endothelial cells under flow conditions , 2009, Journal of Neuroimmunology.

[40]  T. Kirchhausen,et al.  Lymphocyte crawling and transendothelial migration require chemokine triggering of high-affinity LFA-1 integrin. , 2009, Immunity.

[41]  Yongxiang Gao,et al.  Accurate detection and complete tracking of large populations of features in three dimensions. , 2009, Optics express.

[42]  S. Barnum,et al.  Effector and suppressor roles for LFA-1 during the development of experimental autoimmune encephalomyelitis , 2009, Journal of Neuroimmunology.

[43]  K. Ley,et al.  Leukocyte adhesion molecules in animal models of inflammatory bowel disease , 2008, Inflammatory bowel diseases.

[44]  Jay X. Tang,et al.  Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration , 2008, The Journal of experimental medicine.

[45]  M. Cybulsky,et al.  Getting to the site of inflammation: the leukocyte adhesion cascade updated , 2007, Nature Reviews Immunology.

[46]  R. Geha,et al.  Transcellular diapedesis is initiated by invasive podosomes. , 2007, Immunity.

[47]  D. Ostanin,et al.  T cell-associated CD18 but not CD62L, ICAM-1, or PSGL-1 is required for the induction of chronic colitis. , 2007, American journal of physiology. Gastrointestinal and liver physiology.

[48]  P. Kubes,et al.  Reevaluation of P-Selectin and α4 Integrin as Targets for the Treatment of Experimental Autoimmune Encephalomyelitis1 , 2006, The Journal of Immunology.

[49]  Ludwig Kappos,et al.  A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. , 2006, The New England journal of medicine.

[50]  D. Ostanin,et al.  Role of T-cell-associated lymphocyte function-associated antigen-1 in the pathogenesis of experimental colitis. , 2006, International immunology.

[51]  L. Fenart,et al.  Mouse syngenic in vitro blood–brain barrier model: a new tool to examine inflammatory events in cerebral endothelium , 2005, Laboratory Investigation.

[52]  K. Ley,et al.  Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation , 2004, Nature Reviews Immunology.

[53]  R. Ahmed,et al.  CD43 Modulates Severity and Onset of Experimental Autoimmune Encephalomyelitis 1 , 2003, The Journal of Immunology.

[54]  H. Weiner,et al.  Myelin Oligodendrocyte Glycoprotein–specific T Cell Receptor Transgenic Mice Develop Spontaneous Autoimmune Optic Neuritis , 2003, The Journal of experimental medicine.

[55]  David H. Miller,et al.  A controlled trial of natalizumab for relapsing multiple sclerosis. , 2003, The New England journal of medicine.

[56]  P. Kubes,et al.  Overlapping Roles of P-Selectin and α4 Integrin to Recruit Leukocytes to the Central Nervous System in Experimental Autoimmune Encephalomyelitis1 , 2002, The Journal of Immunology.

[57]  B. Engelhardt,et al.  Interaction of α4-integrin with VCAM-1 is involved in adhesion of encephalitogenic T cell blasts to brain endothelium but not in their transendothelial migration in vitro , 2000, Journal of Neuroimmunology.

[58]  G. Nuki,et al.  CD44 is involved in selective leucocyte extravasation during inflammatory central nervous system disease , 1999, Immunology.

[59]  I. Weissman,et al.  Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[60]  H. Degrendele,et al.  Requirement for CD44 in activated T cell extravasation into an inflammatory site. , 1997, Science.

[61]  L. Picker,et al.  CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway , 1996, The Journal of experimental medicine.

[62]  Y. Ron,et al.  Bothanti-CD11a(LFA-l) and anti-CD11b (MAC-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis , 1995, Journal of Neuroimmunology.

[63]  J. Greenwood,et al.  Lymphocyte adhesion and transendothelial migration in the central nervous system: the role of LFA-1, ICAM-1, VLA-4 and VCAM-1. off. , 1995, Immunology.

[64]  B. Engelhardt,et al.  Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interaction with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse. , 1994, The American journal of pathology.

[65]  E. Puré,et al.  CD44 is necessary for optimal contact allergic responses but is not required for normal leukocyte extravasation , 1993, The Journal of experimental medicine.

[66]  C. Janeway,et al.  Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma , 1993, The Journal of experimental medicine.

[67]  F. Sánchez‐Madrid,et al.  Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin , 1992, Nature.

[68]  E. Ruitenberg,et al.  The ‘Swiss roll’: a simple technique for histological studies of the rodent intestine , 1981, Laboratory animals.

[69]  C. Bock,et al.  A T cell-specific deletion of HDAC1 protects against experimental autoimmune encephalomyelitis. , 2018, Journal of Autoimmunity.

[70]  P. Kincade,et al.  CD44 and its interaction with extracellular matrix. , 1993, Advances in immunology.