Quasi-spherical microwells on superhydrophobic substrates for long term culture of multicellular spheroids and high throughput assays.

[1]  R. Huang,et al.  Modeling of cancer metastasis and drug resistance via biomimetic nano-cilia and microfluidics. , 2014, Biomaterials.

[2]  Roger D. Kamm,et al.  Rapid Prototyping of Concave Microwells for the Formation of 3D Multicellular Cancer Aggregates for Drug Screening , 2013, Advanced healthcare materials.

[3]  Dong Yun Lee,et al.  3D co-culturing model of primary pancreatic islets and hepatocytes in hybrid spheroid to overcome pancreatic cell shortage. , 2013, Biomaterials.

[4]  V. Virador,et al.  In vitro three‐dimensional (3D) models in cancer research: An update , 2013, Molecular carcinogenesis.

[5]  L. O’Driscoll,et al.  Three-dimensional cell culture: the missing link in drug discovery. , 2013, Drug discovery today.

[6]  A. Donnenberg,et al.  Flow cytometric determination of stem/progenitor content in epithelial tissues: An example from nonsmall lung cancer and normal lung , 2013, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[7]  Gi Seok Jeong,et al.  Surface Tension‐Mediated, Concave‐Microwell Arrays for Large‐Scale, Simultaneous Production of Homogeneously Sized Embryoid Bodies , 2013, Advanced healthcare materials.

[8]  Francesca Orso,et al.  p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells , 2012, Breast Cancer Research.

[9]  Ji Yoon Kang,et al.  On-chip anticancer drug test of regular tumor spheroids formed in microwells by a distributive microchannel network. , 2012, Lab on a chip.

[10]  Raha Abdul Rahim,et al.  Development of Multicellular Tumor Spheroid (MCTS) Culture from Breast Cancer Cell and a High Throughput Screening Method Using the MTT Assay , 2012, PloS one.

[11]  Ching-Te Kuo,et al.  Configurable 2D and 3D spheroid tissue cultures on bioengineered surfaces with acquisition of epithelial–mesenchymal transition characteristics , 2012 .

[12]  Youchun Xu,et al.  Rapid fabrication of a microdevice with concave microwells and its application in embryoid body formation. , 2012, Biomicrofluidics.

[13]  Jenny C. Chang,et al.  Epithelial-mesenchymal transition, cancer stem cells and treatment resistance , 2012, Breast Cancer Research.

[14]  Gi Seok Jeong,et al.  Meniscus induced self organization of multiple deep concave wells in a microchannel for embryoid bodies generation. , 2012, Lab on a chip.

[15]  Dong Yun Lee,et al.  In situ formation and collagen-alginate composite encapsulation of pancreatic islet spheroids. , 2012, Biomaterials.

[16]  Min Jun Kim,et al.  Functional clustering of pancreatic islet cells using concave microwell array , 2011 .

[17]  Bong Geun Chung,et al.  Concave microwell based size-controllable hepatosphere as a three-dimensional liver tissue model. , 2011, Biomaterials.

[18]  K. Lee,et al.  Diffusion-mediated in situ alginate encapsulation of cell spheroids using microscale concave well and nanoporous membrane. , 2011, Lab on a chip.

[19]  Mary Kay Harper,et al.  3D Models of Epithelial-Mesenchymal Transition in Breast Cancer Metastasis , 2011, Journal of biomolecular screening.

[20]  Bong Geun Chung,et al.  Development of a multi-layer microfluidic array chip to culture and replate uniform-sized embryoid bodies without manual cell retrieval. , 2010, Lab on a chip.

[21]  L. Kunz-Schughart,et al.  Multicellular tumor spheroids: an underestimated tool is catching up again. , 2010, Journal of biotechnology.

[22]  R. Goldman,et al.  Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[23]  Ali Khademhosseini,et al.  Controlled-size embryoid body formation in concave microwell arrays. , 2010, Biomaterials.

[24]  Marcus Textor,et al.  Integration column: microwell arrays for mammalian cell culture. , 2009, Integrative biology : quantitative biosciences from nano to macro.

[25]  F. Guittard,et al.  Fabrication of superhydrophobic PDMS surfaces by combining acidic treatment and perfluorinated monolayers. , 2009, Langmuir : the ACS journal of surfaces and colloids.

[26]  Chang Mo Hwang,et al.  Ice-lithographic fabrication of concave microwells and a microfluidic network , 2009, Biomedical microdevices.

[27]  J. Zavadil,et al.  Epithelial-mesenchymal transition. , 2008, Cancer research.

[28]  Hwan-You Chang,et al.  Recent advances in three‐dimensional multicellular spheroid culture for biomedical research , 2008, Biotechnology journal.

[29]  Shih-hui Chao,et al.  Rapid fabrication of microchannels using microscale plasma activated templating (microPLAT) generated water molds. , 2007, Lab on a chip.

[30]  Raghu Kalluri,et al.  The epithelial–mesenchymal transition: new insights in signaling, development, and disease , 2006, The Journal of cell biology.

[31]  M. Tarpin,et al.  In vitro and in vivo anti‐tumoral effect of curcumin against melanoma cells , 2004, International journal of cancer.

[32]  M. O'hare,et al.  Three-dimensional in vitro tissue culture models of breast cancer — a review , 2004, Breast Cancer Research and Treatment.

[33]  J. Thiery.  Epithelial–mesenchymal transitions in tumour progression , 2002, Nature Reviews Cancer.

[34]  M. Bibby,et al.  Influence of drug exposure parameters on the activity of paclitaxel in multicellular spheroids. , 1997, European journal of cancer.

[35]  F. Denizot,et al.  Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. , 1986, Journal of immunological methods.