论文信息 - The “Pink Spot” in Schizophrenics and its Absence in Homocystinurics

The “Pink Spot” in Schizophrenics and its Absence in Homocystinurics

In 1952 Osmond and Smythies, with Harley-Mason, suggested that schizophrenia might be due to an abnormality in the metabolism of epinephrine, by which a mescaline-like substance such as dimethoxyphenylethylamine (DMPE) might be produced by O-methylation at the third and fourth positions. It was felt then that DMPE might have “psychotomimetic properties” similar to mescaline.

J. Welch | R. Schimke | C. Clower

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