Butein Suppresses Constitutive and Inducible Signal Transducer and Activator of Transcription (STAT) 3 Activation and STAT3-Regulated Gene Products through the Induction of a Protein Tyrosine Phosphatase SHP-1
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B. Aggarwal | K. Ahn | B. Sung | M. Pandey | Bokyung Sung
[1] B. Aggarwal,et al. Butein, a Tetrahydroxychalcone, Inhibits Nuclear Factor (NF)-κB and NF-κB-regulated Gene Expression through Direct Inhibition of IκBα Kinase β on Cysteine 179 Residue* , 2007, Journal of Biological Chemistry.
[2] B. Aggarwal,et al. Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. , 2007, Blood.
[3] Zhizhuang Joe Zhao,et al. Erlotinib Effectively Inhibits JAK2V617F Activity and Polycythemia Vera Cell Growth* , 2006, Journal of Biological Chemistry.
[4] B. Aggarwal,et al. Targeting Signal‐Transducer‐and‐Activator‐of‐Transcription‐3 for Prevention and Therapy of Cancer , 2006, Annals of the New York Academy of Sciences.
[5] V. Poli,et al. Cutting Edge: Inherent and Acquired Resistance to Radiation-Induced Apoptosis in B Cells: A Pivotal Role for STAT31 , 2006, The Journal of Immunology.
[6] D. Sohn,et al. 2',4',6'-Tris(methoxymethoxy) chalcone attenuates hepatic stellate cell proliferation by a heme oxygenase-dependent pathway. , 2006, Biochemical pharmacology.
[7] R. Lai,et al. Loss of SHP1 enhances JAK3/STAT3 signaling and decreases proteosome degradation of JAK3 and NPM-ALK in ALK+ anaplastic large-cell lymphoma. , 2006, Blood.
[8] M. Cavo. Proteasome inhibitor bortezomib for the treatment of multiple myeloma , 2006, Leukemia.
[9] S. Kook,et al. Flavonoids purified from Rhus verniciflua Stokes actively inhibit cell growth and induce apoptosis in human osteosarcoma cells. , 2005, Biochimica et biophysica acta.
[10] Shiuan Chen,et al. The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing aromatase. , 2005, Life sciences.
[11] Y. Jang,et al. Extract from Rhus verniciflua Stokes is capable of inhibiting the growth of human lymphoma cells. , 2004, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[12] Y. Kwong,et al. SOCS1 and SHP1 hypermethylation in multiple myeloma: implications for epigenetic activation of the Jak/STAT pathway. , 2004, Blood.
[13] Lijun Liu,et al. The function of the protein tyrosine phosphatase SHP-1 in cancer. , 2003, Gene.
[14] K. Hayashi,et al. Gene silencing of the tyrosine phosphatase SHP1 gene by aberrant methylation in leukemias/lymphomas. , 2002, Cancer research.
[15] Hua Yu,et al. Roles of activated Src and Stat3 signaling in melanoma tumor cell growth , 2002, Oncogene.
[16] Wenzheng Zhang,et al. Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor κB , 2002 .
[17] Stuart A. Lipton,et al. Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-κB signalling cascades , 2001, Nature.
[18] Youn-Chul Kim,et al. Butein, a plant polyphenol, induces apoptosis concomitant with increased caspase-3 activity, decreased Bcl-2 expression and increased Bax expression in HL-60 cells. , 2001, Pharmacology & toxicology.
[19] Josef M. Penninger,et al. CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling , 2001, Nature.
[20] J. Turkson,et al. Activation of Stat3 in v-Src-transformed Fibroblasts Requires Cooperation of Jak1 Kinase Activity* , 2000, The Journal of Biological Chemistry.
[21] Roy Garcia,et al. STATs in oncogenesis , 2000, Oncogene.
[22] M. Kobori,et al. Flavonoids Inhibit Cell Growth and Induce Apoptosis in B16 Melanoma 4A5 Cells , 2000, Bioscience, biotechnology, and biochemistry.
[23] C. Geisler,et al. Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[24] Tong Zhang,et al. Protein Kinase C δ Associates with and Phosphorylates Stat3 in an Interleukin-6-dependent Manner* , 1999, The Journal of Biological Chemistry.
[25] R. Jove,et al. Activation of STAT3 by the c-Fes Protein-tyrosine Kinase* , 1998, The Journal of Biological Chemistry.
[26] John Calvin Reed,et al. BCL-X expression in multiple myeloma: possible indicator of chemoresistance. , 1998, Cancer research.
[27] G. Núñez,et al. Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death. , 1997, Blood.
[28] A. Levitzki,et al. Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor , 1996, Nature.
[29] N. Danial,et al. Jak-STAT signaling induced by the v-abl oncogene. , 1995, Science.
[30] R. Jove,et al. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. , 1995, Science.
[31] C. Yit,et al. Cytotoxic effect of butein on human colon adenocarcinoma cell proliferation. , 1994, Cancer letters.
[32] W. Willett,et al. Diet and health: what should we eat? , 1994, Science.
[33] J. Darnell,et al. A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma. , 1993, Science.
[34] H. Asaoku,et al. Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas , 1988, Nature.
[35] J. Pontén,et al. Established immunoglobulin producing myeloma (IgE) and lymphoblastoid (IgG) cell lines from an IgE myeloma patient. , 1970, Clinical and experimental immunology.
[36] J. Turkson,et al. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. , 1999, Immunity.