The spatial organization of the human genome.
暂无分享,去创建一个
[1] Jennifer A. Mitchell,et al. Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells , 2010, Nature Genetics.
[2] F. Grosveld,et al. Three-dimensional organization of gene expression in erythroid cells. , 2008, Current topics in developmental biology.
[3] Nick Gilbert,et al. Chromatin Architecture of the Human Genome Gene-Rich Domains Are Enriched in Open Chromatin Fibers , 2004, Cell.
[4] Matthew J. Rodesch,et al. Fluorescence in situ hybridization with high-complexity repeat-free oligonucleotide probes generated by massively parallel synthesis , 2011, Chromosome Research.
[5] Thomas Cremer,et al. 4D chromatin dynamics in cycling cells: Theodor Boveri's hypotheses revisited. , 2010, Nucleus.
[6] P. Mombaerts,et al. Local and cis Effects of the H Element on Expression of Odorant Receptor Genes in Mouse , 2007, Cell.
[7] J. Lawrence,et al. The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules , 2011, Nature Structural &Molecular Biology.
[8] E. Bertolino,et al. Transcriptional repression mediated by repositioning of genes to the nuclear lamina , 2008, Nature.
[9] W. Bickmore,et al. Genes and genomes: chromosome bands – flavours to savour , 1993 .
[10] H. Tanabe,et al. Chromosomal dynamics at the Shh locus: limb bud-specific differential regulation of competence and active transcription. , 2009, Developmental cell.
[11] Thomas Cremer,et al. Radial chromatin positioning is shaped by local gene density, not by gene expression , 2007, Chromosoma.
[12] W. Bickmore,et al. Stable Morphology, but Dynamic Internal Reorganisation, of Interphase Human Chromosomes in Living Cells , 2010, PloS one.
[13] B. van Steensel,et al. Interactions among Polycomb Domains Are Guided by Chromosome Architecture , 2011, PLoS genetics.
[14] Reza Kalhor,et al. Genome architectures revealed by tethered chromosome conformation capture and population-based modeling , 2011, Nature Biotechnology.
[15] Christopher H Eskiw,et al. Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford progeria syndrome cells , 2011, Genome Biology.
[16] W. Bickmore,et al. Transcription and the nuclear periphery: edge of darkness? , 2009, Current opinion in genetics & development.
[17] B. Steensel,et al. Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C) , 2006, Nature Genetics.
[18] A. Lamond,et al. High-Resolution Whole-Genome Sequencing Reveals That Specific Chromatin Domains from Most Human Chromosomes Associate with Nucleoli , 2010, Molecular biology of the cell.
[19] Wendy A. Bickmore,et al. The Radial Positioning of Chromatin Is Not Inherited through Mitosis but Is Established De Novo in Early G1 , 2004, Current Biology.
[20] Wendy A. Bickmore,et al. Gene density and transcription influence the localization of chromatin outside of chromosome territories detectable by FISH , 2002, The Journal of cell biology.
[21] D. Spector,et al. A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence , 2008, The Journal of cell biology.
[22] Michael O Dorschner,et al. Sequencing newly replicated DNA reveals widespread plasticity in human replication timing , 2009, Proceedings of the National Academy of Sciences.
[23] J. Sedat,et al. Spatial partitioning of the regulatory landscape of the X-inactivation centre , 2012, Nature.
[24] Francis S. Collins,et al. A lamin A protein isoform overexpressed in Hutchinson–Gilford progeria syndrome interferes with mitosis in progeria and normal cells , 2007, Proceedings of the National Academy of Sciences.
[25] M. Hosoya,et al. Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb , 2005, Development.
[26] Dirk Schübeler,et al. Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation , 2008, PLoS biology.
[27] Richard Axel,et al. Interchromosomal Interactions and Olfactory Receptor Choice , 2006, Cell.
[28] A. Harvey,et al. Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts , 2010, Genome Biology.
[29] J. Stamatoyannopoulos,et al. Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements. , 2011, Genome research.
[30] W. Bickmore,et al. Lack of bystander activation shows that localization exterior to chromosome territories is not sufficient to up-regulate gene expression. , 2009, Genome research.
[31] Wouter de Laat,et al. A Regulatory Archipelago Controls Hox Genes Transcription in Digits , 2011, Cell.
[32] Robert-Jan Palstra,et al. HERC2 rs12913832 modulates human pigmentation by attenuating chromatin-loop formation between a long-range enhancer and the OCA2 promoter. , 2012, Genome research.
[33] I. Amit,et al. Comprehensive mapping of long range interactions reveals folding principles of the human genome , 2011 .
[34] P. Laird,et al. Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains , 2011, Nature Genetics.
[35] T. Shimi,et al. Alterations in mitosis and cell cycle progression caused by a mutant lamin A known to accelerate human aging , 2007, Proceedings of the National Academy of Sciences.
[36] H. Sakano,et al. Deletion of the core-H region in mice abolishes the expression of three proximal odorant receptor genes in cis , 2007, Proceedings of the National Academy of Sciences.
[37] Juliet A. Ellis,et al. The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells. , 2001, Human molecular genetics.
[38] Shane J. Neph,et al. Systematic Localization of Common Disease-Associated Variation in Regulatory DNA , 2012, Science.
[39] M. Thayer,et al. Engineering translocations with delayed replication: evidence for cis control of chromosome replication timing. , 2005, Human molecular genetics.
[40] T. Misteli,et al. Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus , 2006, Journal of Cell Science.
[41] A. Fisher,et al. Nuclear repositioning marks the selective exclusion of lineage‐inappropriate transcription factor loci during T helper cell differentiation , 2004, European journal of immunology.
[42] W. V. van IJcken,et al. The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA. , 2011, Genes & development.
[43] Tom Misteli,et al. Spatial proximity of translocation-prone gene loci in human lymphomas , 2003, Nature Genetics.
[44] J. Dekker,et al. The long-range interaction landscape of gene promoters , 2012, Nature.
[45] Thomas Cremer,et al. Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells , 2004, Chromosome Research.
[46] C. Nusbaum,et al. Chromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elements. , 2006, Genome research.
[47] F. Grosveld,et al. Super-resolution imaging reveals three-dimensional folding dynamics of the &bgr;-globin locus upon gene activation , 2012, Journal of Cell Science.
[48] W. D. Laat,et al. A Decade of 3c Technologies: Insights into Nuclear Organization References , 2022 .
[49] Angus I. Lamond,et al. Spatial Organization of Large-Scale Chromatin Domains in the Nucleus: A Magnified View of Single Chromosome Territories , 1997, The Journal of cell biology.
[50] Swneke D. Bailey,et al. Integrative functional genomics identifies an enhancer looping to the SOX9 gene disrupted by the 17q24.3 prostate cancer risk locus , 2012, Genome research.
[51] Wouter de Laat,et al. Variegated gene expression caused by cell-specific long-range DNA interactions , 2011, Nature Cell Biology.
[52] A. Pombo,et al. Intermingling of Chromosome Territories in Interphase Suggests Role in Translocations and Transcription-Dependent Associations , 2006, PLoS biology.
[53] Wendy A Bickmore,et al. Nuclear re-organisation of the Hoxb complex during mouse embryonic development , 2005, Development.
[54] Elizabeth Kerr,et al. Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells , 2008, PLoS genetics.
[55] A. Pombo,et al. Transcription and Chromatin Organization of a Housekeeping Gene Cluster Containing an Integrated β-Globin Locus Control Region , 2008, PLoS genetics.
[56] R. Eils,et al. Three-Dimensional Maps of All Chromosomes in Human Male Fibroblast Nuclei and Prometaphase Rosettes , 2005, PLoS biology.
[57] Pierre Chartrand,et al. Genome-wide scanning of HoxB1-associated loci in mouse ES cells using an open-ended Chromosome Conformation Capture methodology , 2006, Chromosome Research.
[58] T. Misteli,et al. Mapping of lamin A- and progerin-interacting genome regions , 2012, Chromosoma.
[59] Wendy A Bickmore,et al. Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination. , 2010, Molecular cell.
[60] Arcadi Navarro,et al. Chromosomal rearrangements and the genomic distribution of gene-expression divergence in humans and chimpanzees. , 2004, Trends in genetics : TIG.
[61] B. Trask,et al. Regional differences in the compaction of chromatin in human G0/G1 interphase nuclei , 1997, Chromosome Research.
[62] W. Bickmore,et al. Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription. , 2004, Genes & development.
[63] Michael D. Wilson,et al. Replication-timing boundaries facilitate cell-type and species-specific regulation of a rearranged human chromosome in mouse. , 2012, Human molecular genetics.
[64] M. Vázquez,et al. Chromosomes are predominantly located randomly with respect to each other in interphase human cells , 2002, The Journal of cell biology.
[65] W. Bickmore,et al. Nuclear organization of centromeric domains is not perturbed by inhibition of histone deacetylases , 2004, Chromosome Research.
[66] Thomas Cremer,et al. Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages , 2003, The Journal of cell biology.
[67] Michael S. Becker,et al. Spatial Organization of the Mouse Genome and Its Role in Recurrent Chromosomal Translocations , 2012, Cell.
[68] P. Schultz,et al. The linker histone H1C contributes to the SCA7 nuclear phenotype , 2011, Nucleus.
[69] W. Bickmore,et al. Re-modelling of nuclear architecture in quiescent and senescent human fibroblasts , 2000, Current Biology.
[70] L. Lettice,et al. Preaxial polydactyly: a model for defective long-range regulation in congenital abnormalities. , 2005, Current opinion in genetics & development.
[71] A. Conesa,et al. Initial Genomics of the Human Nucleolus , 2010, PLoS genetics.
[72] L. Wessels,et al. Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions , 2008, Nature.
[73] Carol J. Bult,et al. Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence , 2006, The Journal of cell biology.
[74] Jesse R. Dixon,et al. Topological Domains in Mammalian Genomes Identified by Analysis of Chromatin Interactions , 2012, Nature.
[75] Roland Eils,et al. Separate and variably shaped chromosome arm domains are disclosed by chromosome arm painting in human cell nuclei , 1998, Chromosome Research.
[76] Cameron S. Osborne,et al. Myc Dynamically and Preferentially Relocates to a Transcription Factory Occupied by Igh , 2007, PLoS biology.
[77] A. Tanay,et al. Probabilistic modeling of Hi-C contact maps eliminates systematic biases to characterize global chromosomal architecture , 2011, Nature Genetics.
[78] T. Cremer,et al. Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes , 2004, Chromosome Research.
[79] Thomas Cremer,et al. Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution , 2009, Cell.
[80] Peter Teague,et al. Differences in the Localization and Morphology of Chromosomes in the Human Nucleus , 1999, The Journal of cell biology.
[81] A. Tanay,et al. Three-Dimensional Folding and Functional Organization Principles of the Drosophila Genome , 2012, Cell.
[82] Nathan C. Sheffield,et al. The accessible chromatin landscape of the human genome , 2012, Nature.
[83] D. Kleinjan,et al. Long-range control of gene expression: emerging mechanisms and disruption in disease. , 2005, American journal of human genetics.
[84] A. Munnich,et al. Highly conserved non-coding elements on either side of SOX9 associated with Pierre Robin sequence , 2009, Nature Genetics.
[85] L. Peichl,et al. LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation , 2013, Cell.
[86] A. Reymond,et al. The effect of translocation-induced nuclear reorganization on gene expression. , 2010, Genome research.
[87] W. Bickmore,et al. Influences of chromosome size, gene density and nuclear position on the frequency of constitutional translocations in the human population , 2004, Chromosome Research.
[88] F. Iborra,et al. Association between active genes occurs at nuclear speckles and is modulated by chromatin environment , 2008, The Journal of cell biology.
[89] Wendy A. Bickmore,et al. Anterior-posterior differences in HoxD chromatin topology in limb development , 2012, Development.
[90] Veronica J. Buckle,et al. Coregulated human globin genes are frequently in spatial proximity when active , 2006, The Journal of cell biology.
[91] Jean Thierry-Mieg,et al. Predictable dynamic program of timing of DNA replication in human cells. , 2009, Genome research.
[92] Tyrone Ryba,et al. Abnormal developmental control of replication-timing domains in pediatric acute lymphoblastic leukemia , 2012, Genome research.
[93] Wendy A Bickmore,et al. Nuclear reorganisation and chromatin decondensation are conserved, but distinct, mechanisms linked to Hox gene activation , 2007, Development.
[94] P. Flicek,et al. Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation. , 2010, Molecular cell.
[95] E. Cabuy,et al. Primary laminopathy fibroblasts display altered genome organization and apoptosis , 2007, Aging cell.
[96] Abdelkader Essafi,et al. Opposing Functions of the ETS Factor Family Define Shh Spatial Expression in Limb Buds and Underlie Polydactyly , 2012, Developmental cell.
[97] T. Cremer,et al. Evolutionarily conserved, cell type and species-specific higher order chromatin arrangements in interphase nuclei of primates , 2007, Chromosoma.
[98] Roy Riblet,et al. Subnuclear Compartmentalization of Immunoglobulin Loci During Lymphocyte Development , 2002, Science.
[99] D L Spector,et al. Dynamic organization of DNA replication in mammalian cell nuclei: spatially and temporally defined replication of chromosome-specific alpha-satellite DNA sequences , 1992, The Journal of cell biology.
[100] P. Gregory,et al. Controlling Long-Range Genomic Interactions at a Native Locus by Targeted Tethering of a Looping Factor , 2012, Cell.
[101] S. Dalton,et al. Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types. , 2010, Genome research.
[102] B. Alter,et al. Gamma delta beta-thalassemia due to a de novo mutation deleting the 5' beta-globin gene activation-region hypersensitive sites. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[103] Kaushik Sengupta,et al. Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin. , 2008, Genes & development.
[104] Wendy A. Bickmore,et al. Transcription factories: gene expression in unions? , 2009, Nature Reviews Genetics.