Digitized evaluation system for super-information characteristics of chromatographic fingerprintsin in traditional Chinese medicine

Objective To introduce both the construction frame and the core techniques of the software "Digitized Evaluation System for Super-information Characteristics of the Traditional Chinese Medicine(TCM) Chromatographic Fingerprints 3.0".Methods The software published:①the characteristic technique parameters of fingerprint peaks;②the digitized criterion parameters of potential characteristic information of chromatographic fingerprints,in which the potential information of chromatographic fingerprints was mined by digital core parameters such as the chromatographic fingerprint index,and the chromatographic fingerprint information index,and the chromatographic fingerprint resolution index;③ the qualitative similarity and quantitative similarity criterion parameters;and ④the unified criterion parameters of the relative characteristics of chromatographic fingerprints,etc,which can calculate the 4 parameters to serve as the criteria for the information quanlity control for TCM.Results We published ①15 of the characteristic technique parameters of fingerprint peaks;②42 of the digitized criterion parameters of potential characteristic infornation of chromatographic fingerprints;③ 32 of the qualitative similarity and quantitative similarity criterion parameters,1 to 4 of which may lead to a definite result;and ④25 of the unified criterion parameters of the relative characteristics of chromatographic fingerprints to serve as the bases that constructed the digitized fingerprints,which clearly and thoroughly reflected and controlled the quanlity of TCM.Conclusion The software "Digitized Evaluation System for Super-information Characteristics of the Traditional Chinese Medicine Chromatographic Fingerprints 3.0" is an important and effective tool to determine the digitized fingerprint of TCM.Its 114 parameters construct the important core techniques of TCM digitized fingerprints,and it is the best technique and the most proper quanlity control method for modern TCM.