Fabrication of nanofiber-based SERS-active substrates by oxygen plasma removal of SU-8 photoresist

We present for the first time an approach to fabricate surface enhanced Raman scattering (SERS)-active substrates based on nanofibers simply by removing SU-8 photoresist in oxygen plasma bombardment. Compared with Raman spectral signals of Rhodamine B on smooth silicon substrates, the intensity of those on the nanofiber-based SERS-active substrates are much more distinctive and are at least 103 folds greater. Moreover, the approach can be combined with conventional photolithography for fabricating photo-patternable SERS-active structures, together with the high hydrophilicity of the nanofibers, chemical reagents can be self-patterned in the SERS-active devices, which may have a variety of important applications in different fields.

[1]  Yilong Hao,et al.  The fabrication of diversiform nanostructure forests based on residue nanomasks synthesized by oxygen plasma removal of photoresist , 2009, Nanotechnology.

[2]  A. Kudelski.  Raman studies of rhodamine 6G and crystal violet sub-monolayers on electrochemically roughened silver substrates: Do dye molecules adsorb preferentially on highly SERS-active sites? , 2005 .

[3]  R. Dasari,et al.  Single Molecule Detection Using Surface-Enhanced Raman Scattering (SERS) , 1997 .

[4]  Luke P. Lee,et al.  Nanowell surface enhanced Raman scattering arrays fabricated by soft-lithography for label-free biomolecular detections in integrated microfluidics , 2005 .

[5]  Naomi J Halas,et al.  Aromatic amino acids providing characteristic motifs in the Raman and SERS spectroscopy of peptides. , 2008, The journal of physical chemistry. B.

[6]  Jacopo Tomasi,et al.  Surface enhanced Raman scattering from a single molecule adsorbed on a metal particle aggregate: A theoretical study , 2002 .

[7]  George C. Schatz,et al.  Nanosphere Lithography: Effect of Substrate on the Localized Surface Plasmon Resonance Spectrum of Silver Nanoparticles , 2001 .

[8]  Brian M. Cullum,et al.  Characterization of novel gold SERS substrates with multilayer enhancements , 2006, SPIE Optics East.

[9]  A. OTrO,et al.  Surface-Enhanced Raman Scattering of Adsorbates , 2006 .

[10]  De‐Yin Wu,et al.  Surface-Enhanced Raman Scattering: From Noble to Transition Metals and from Rough Surfaces to Ordered Nanostructures , 2002 .

[11]  Y.L. Hao,et al.  Fabrication of Nanopillars based on Silicon Oxide Nanopatterns Synthesized in Oxygen Plasma Removal of Photoresist , 2009, 2009 IEEE 22nd International Conference on Micro Electro Mechanical Systems.

[12]  Joel I. Gersten,et al.  The effect of surface roughness on surface enhanced Raman scattering , 1980 .

[13]  M. Fleischmann,et al.  Raman spectra of pyridine adsorbed at a silver electrode , 1974 .