Pharmacology of airway inflammation in asthma and COPD.
暂无分享,去创建一个
[1] R. Schleimer,et al. An overview of glucocorticoid anti-inflammatory actions , 2005, European Journal of Clinical Pharmacology.
[2] A. Yorgancioglu,et al. Prevalence of Chlamydia pneumoniae specific antibodies in different clinical situations and healthy subjects in Izmir, Turkey , 1998, European Journal of Epidemiology.
[3] H. Nelson,et al. Enhanced synergy between fluticasone propionate and salmeterol inhaled from a single inhaler versus separate inhalers. , 2003, The Journal of allergy and clinical immunology.
[4] D. Rogers. Airway hypersecretion in allergic rhinitis and asthma: New pharmacotherapy , 2003, Current allergy and asthma reports.
[5] I. Adcock. Glucocorticoids: New mechanisms and future agents , 2003, Current allergy and asthma reports.
[6] P. Barnes. Theophylline: new perspectives for an old drug. , 2003, American journal of respiratory and critical care medicine.
[7] A. Burks,et al. Effect of anti-IgE therapy in patients with peanut allergy. , 2003, The New England journal of medicine.
[8] L. Fabbri,et al. Predominant emphysema phenotype in chronic obstructive pulmonary disease patients , 2003, European Respiratory Journal.
[9] R. Pauwels,et al. Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial , 2003, The Lancet.
[10] L. Corbetta,et al. Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease. , 2003, American journal of respiratory and critical care medicine.
[11] F. Sinigaglia,et al. Chemokine receptors in inflammation: an overview. , 2003, Journal of immunological methods.
[12] A. Kay,et al. Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway. , 2003, American journal of respiratory and critical care medicine.
[13] W. Henderson,et al. CCR8 Is Not Essential for the Development of Inflammation in a Mouse Model of Allergic Airway Disease , 2003, The Journal of Immunology.
[14] P. Barnes. New treatments for chronic obstructive pulmonary disease. , 2001, Current opinion in pharmacology.
[15] P. Korenblat,et al. A randomized double-blind trial , 2003 .
[16] E. Gelfand. Role of histamine in the pathophysiology of asthma: immunomodulatory and anti-inflammatory activities of H1-receptor antagonists. , 2002, The American journal of medicine.
[17] L. Boulet,et al. Assessment and evaluation of symptomatic steroid-naive asthmatics without sputum eosinophilia and their response to inhaled corticosteroids , 2002, European Respiratory Journal.
[18] R. Dahl,et al. Effects of salmeterol on mucosal inflammation in asthma: a placebo-controlled study , 2002, European Respiratory Journal.
[19] M. Giembycz. 4D or not 4D - the emetogenic basis of PDE4 inhibitors uncovered? , 2002, Trends in pharmacological sciences.
[20] E. Raz,et al. Immunostimulatory sequence oligodeoxynucleotide-based vaccination and immunomodulation: two unique but complementary strategies for the treatment of allergic diseases. , 2002, The Journal of allergy and clinical immunology.
[21] A. Chuchalin,et al. Evaluation of different inhaled combination therapies (EDICT): a randomised, double-blind comparison of Seretide (50/250 microg bd Diskus vs. formoterol (12 microg bd) and budesonide (800 microg bd) given concurrently (both via Turbuhaler) in patients with moderate-to-severe asthma. , 2002, Respiratory medicine.
[22] T. Torphy,et al. What's in the pipeline? Prospects for monoclonal antibodies (mAbs) as therapies for lung diseases. , 2002, Pulmonary pharmacology & therapeutics.
[23] I. Hussain,et al. Modulation of Murine Allergic Rhinosinusitis by CpG Oligodeoxynucleotides , 2002, The Laryngoscope.
[24] M. Weisman. What are the risks of biologic therapy in rheumatoid arthritis? An update on safety. , 2002, The Journal of rheumatology. Supplement.
[25] G. Berry,et al. Antigen-specific regulatory T cells develop via the ICOS–ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity , 2002, Nature Medicine.
[26] P. Jeffery,et al. Effects of fluticasone propionate on inflammatory cells in COPD: an ultrastructural examination of endobronchial biopsy tissue , 2002, Thorax.
[27] Peter Reid,et al. Roflumilast Altana Pharma. , 2002, Current opinion in investigational drugs.
[28] A. Buist. Guidelines for the management of chronic obstructive pulmonary disease. , 2002, Respiratory medicine.
[29] H. Hirata,et al. Anti-interleukin-9 antibody treatment inhibits airway inflammation and hyperreactivity in mouse asthma model. , 2002, American journal of respiratory and critical care medicine.
[30] H. Fujiwara,et al. A non‐peptide CCR5 antagonist inhibits collagen‐induced arthritis by modulating T cell migration without affecting anti‐collagen T cell responses , 2002, European journal of immunology.
[31] G. Trainor,et al. CCR3 antagonists: a potential new therapy for the treatment of asthma. Discovery and structure-activity relationships. , 2002, Bioorganic & medicinal chemistry letters.
[32] I. Adcock. Role of mediators in late-phase allergic symptoms including congestion , 2002 .
[33] J. Prandota. Furosemide: Progress in Understanding Its Diuretic, Anti-inflammatory, and Bronchodilating Mechanism of Action, and Use in the Treatment of Respiratory Tract Diseases , 2002, American journal of therapeutics.
[34] P. Barnes,et al. Increased levels of the chemokines GROα and MCP-1 in sputum samples from patients with COPD , 2002, Thorax.
[35] B. Lipworth,et al. Bronchoprotective effects of leukotriene receptor antagonists in asthma: a meta-analysis. , 2002, Chest.
[36] I. Adcock,et al. A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[37] M. Kiniwa,et al. Species-specific differences in the glucocorticoid receptor transactivation function upon binding with betamethasone-esters. , 2002, International immunopharmacology.
[38] G. Rook,et al. Suppression of airway eosinophilia by killed Mycobacterium vaccae-induced allergen-specific regulatory T-cells , 2002, Nature Medicine.
[39] P. Barnes. New treatments for copd , 2002, Nature Reviews Drug Discovery.
[40] A. Pahl,et al. Asthma therapy in the new millennium , 2002, Inflammation Research.
[41] C. Burnouf,et al. Recent advances in PDE4 inhibitors as immunoregulators and anti-inflammatory drugs. , 2002, Current pharmaceutical design.
[42] P. Barnes,et al. Effect of theophylline on induced sputum inflammatory indices and neutrophil chemotaxis in chronic obstructive pulmonary disease. , 2002, American journal of respiratory and critical care medicine.
[43] L. Fabbri,et al. Increased expression of the chemokine receptor CXCR3 and its ligand CXCL10 in peripheral airways of smokers with chronic obstructive pulmonary disease. , 2002, American journal of respiratory and critical care medicine.
[44] Stephen C Lazarus,et al. Systemic effect comparisons of six inhaled corticosteroid preparations. , 2002, American journal of respiratory and critical care medicine.
[45] W. D. Boer. Cytokines and therapy in COPD: A promising combination? , 2002 .
[46] I. Hall,et al. The selective CXCR2 antagonist SB272844 blocks interleukin-8 and growth-related oncogene-alpha-mediated inhibition of spontaneous neutrophil apoptosis. , 2002, Pulmonary pharmacology & therapeutics.
[47] S. Romagnani. Cytokines and chemoattractants in allergic inflammation. , 2002, Molecular immunology.
[48] L. Borish. The role of leukotrienes in upper and lower airway inflammation and the implications for treatment. , 2002, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
[49] D. Johns,et al. Airway inflammation, basement membrane thickening and bronchial hyperresponsiveness in asthma , 2002, Thorax.
[50] I. Adcock,et al. Attenuated production of intracellular IL-10 and IL-12 in monocytes from patients with severe asthma. , 2002, Clinical immunology.
[51] M. Adachi,et al. Reduction of eosinophilic inflammation in the airways of patients with asthma using montelukast. , 2002, Chest.
[52] Stephen C Lazarus,et al. Banks CORTICOSTEROIDS FOR PERSISTENT ASTHMA SIGNIFICANT VARIABILITY IN RESPONSE TO INHALED Services , 2022 .
[53] Giembycz Ma. Development status of second generation PDE4 inhibitors for asthma and COPD: the story so far. , 2002 .
[54] U. Lalloo. Symbicort: controlling asthma in adults. , 2002, Respiratory medicine.
[55] C. Hawrylowicz,et al. A defect in corticosteroid-induced IL-10 production in T lymphocytes from corticosteroid-resistant asthmatic patients. , 2002, The Journal of allergy and clinical immunology.
[56] K. Rabe,et al. Selective phosphodiesterase inhibitors for the treatment of asthma and chronic obstructive pulmonary disease , 2002, Current opinion in allergy and clinical immunology.
[57] D. Olivieri,et al. Eotaxin and CCR3 are up‐regulated in exacerbations of chronic bronchitis , 2002, Allergy.
[58] P. Barnes,et al. Scientific rationale for inhaled combination therapy with long-acting β2-agonists and corticosteroids , 2002, European Respiratory Journal.
[59] I. Adcock,et al. Overview: why are corticosteroids ineffective in COPD? , 2002, Current opinion in investigational drugs.
[60] R. Pauwels,et al. Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial. , 2002, American journal of respiratory and critical care medicine.
[61] K. Asadullah,et al. SEGRAs: a novel class of anti-inflammatory compounds. , 2002, Ernst Schering Research Foundation workshop.
[62] S. Umland,et al. Review of the molecular and cellular mechanisms of action of glucocorticoids for use in asthma. , 2002, Pulmonary pharmacology & therapeutics.
[63] T. Shimoda,et al. Effects of pranlukast on chemical mediators in induced sputum on provocation tests in atopic and aspirin-intolerant asthmatic patients. , 2002, Chest.
[64] B. Lipworth,et al. Comparative efficacy and anti-inflammatory profile of once-daily therapy with leukotriene antagonist or low-dose inhaled corticosteroid in patients with mild persistent asthma. , 2002, The Journal of allergy and clinical immunology.
[65] P. Barnes. Cytokine modulators as novel therapies for asthma. , 2002, Annual review of pharmacology and toxicology.
[66] R. Naclerio,et al. Antiallergic anti-inflammatory effects of H1-antihistamines in humans. , 2002, Clinical allergy and immunology.
[67] R. Pauwels,et al. Interleukin-4 and interleukin-5 gene expression and inflammation in the mucus-secreting glands and subepithelial tissue of smokers with chronic bronchitis. Lack of relationship with CD8(+) cells. , 2001, American journal of respiratory and critical care medicine.
[68] S. Till,et al. The immunomodulatory drugs cyclosporin A, mycophenolate mofetil, and sirolimus (rapamycin) inhibit allergen-induced proliferation and IL-5 production by PBMCs from atopic asthmatic patients. , 2001, Journal of Allergy and Clinical Immunology.
[69] S. Holgate,et al. Omalizumab, a novel anti-IgE therapy in allergic disorders , 2001, Expert opinion on biological therapy.
[70] L. Presta,et al. Adapting pharmacokinetic properties of a humanized anti-interleukin-8 antibody for therapeutic applications using site-specific pegylation. , 2001, Cytokine.
[71] R. Pauwels,et al. Airway inflammation and tachykinins: prospects for the development of tachykinin receptor antagonists. , 2001, European journal of pharmacology.
[72] I. Adcock,et al. Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in children with difficult asthma, after treatment with oral prednisolone. , 2001, American journal of respiratory and critical care medicine.
[73] M. Cazzola,et al. Comparison of the Bronchodilating Effect of Salmeterol and Zafirlukast in Combination with That of Their Use as Single Treatments in Asthma and Chronic Obstructive Pulmonary Disease , 2001, Respiration.
[74] D. Postma,et al. Corticosteroid-induced improvement in the PC20 of adenosine monophosphate is more closely associated with reduction in airway inflammation than improvement in the PC20 of methacholine. , 2001, American journal of respiratory and critical care medicine.
[75] G. Fitzmaurice,et al. Effects of inhaled glucocorticoids on bone density in premenopausal women. , 2001, The New England journal of medicine.
[76] R. Pauwels,et al. Long-acting inhaled β2-agonist therapy in asthma , 2001 .
[77] T. Sandström,et al. Effects of budesonide and formoterol on NF-kappaB, adhesion molecules, and cytokines in asthma. , 2001, American journal of respiratory and critical care medicine.
[78] I. Adcock,et al. Expression of GATA family of transcription factors in T-cells, monocytes and bronchial biopsies. , 2001, The European respiratory journal.
[79] R. Dahl,et al. Inhaled formoterol dry powder versus ipratropium bromide in chronic obstructive pulmonary disease. , 2001, American journal of respiratory and critical care medicine.
[80] P. Barnes,et al. Clinical outcome of adding long-acting β-agonists to inhaled corticosteroids , 2001 .
[81] T. Shoji,et al. Cromolyn sodium suppresses eosinophilic inflammation in patients with aspirin-intolerant asthma. , 2001, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
[82] G. Caramori,et al. Cross‐talk between pro‐inflammatory transcription factors and glucocorticoids , 2001, Immunology and cell biology.
[83] R. Pauwels,et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: National Heart, Lung, and Blood Institute and World Health Organization Global Initiative for Chronic Obstructive Lung Disease (GOLD): executive summary. , 2001, Respiratory care.
[84] R. Martin,et al. Evaluation of blood vessels and edema in the airways of asthma patients: regulation with clarithromycin treatment. , 2001, Chest.
[85] R. Townley,et al. The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics. , 2001, The European respiratory journal.
[86] S. Yancey,et al. Salmeterol powder provides significantly better benefit than montelukast in asthmatic patients receiving concomitant inhaled corticosteroid therapy. , 2001, Chest.
[87] C. Brambilla,et al. Cilomilast, a selective phosphodiesterase-4 inhibitor for treatment of patients with chronic obstructive pulmonary disease: a randomised, dose-ranging study , 2001, The Lancet.
[88] A. Medvedev,et al. β-Adrenergic Activation of p38 MAP Kinase in Adipocytes , 2001, The Journal of Biological Chemistry.
[89] I. Adcock,et al. Low-dose theophylline reduces eosinophilic inflammation but not exhaled nitric oxide in mild asthma. , 2001, American journal of respiratory and critical care medicine.
[90] S. Rennard,et al. Alternative Mechanisms for Long-Acting β2-Adrenergic Agonists in COPD , 2001 .
[91] S. Miyazaki,et al. A novel pharmacologic action of glucocorticosteroids on leukotriene C4 catabolism. , 2001, The Journal of allergy and clinical immunology.
[92] N. Inagaki,et al. Drugs for the treatment of allergic diseases. , 2001, Japanese journal of pharmacology.
[93] R. Aalbers,et al. Decreased bronchodilating effect of salbutamol in relieving methacholine induced moderate to severe bronchoconstriction during high dose treatment with long acting β2 agonists , 2001, Thorax.
[94] P. Barnes,et al. Addition of leukotriene antagonists to therapy in chronic persistent asthma: a randomised double-blind placebo-controlled trial , 2001, The Lancet.
[95] M. Neurath,et al. Treatment of Allergic Airway Inflammation and Hyperresponsiveness by Antisense-Induced Local Blockade of Gata-3 Expression , 2001, The Journal of experimental medicine.
[96] I. Adcock,et al. Decreased T lymphocyte infiltration in bronchial biopsies of subjects with severe chronic obstructive pulmonary disease , 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[97] R. Stockley,et al. Changes in bronchial inflammation during acute exacerbations of chronic bronchitis. , 2001, The European respiratory journal.
[98] W. Busse,et al. Efficacy of soluble IL-4 receptor for the treatment of adults with asthma. , 2001, The Journal of allergy and clinical immunology.
[99] D. Mahler,et al. Effectiveness of salmeterol versus ipratropium bromide on exertional dyspnoea in COPD. , 2001, The European respiratory journal.
[100] M. Fukuoka,et al. Effects of suplatast tosilate (IPD Capsules) on the production of active oxygen by neutrophils and of IL-8 by mononuclear cells. , 2001, International immunopharmacology.
[101] C. Owen. Chemokine receptors in airway disease: which receptors to target? , 2001, Pulmonary pharmacology & therapeutics.
[102] R. Brattsand,et al. Effects of formoterol and budesonide on GM-CSF and IL-8 secretion by triggered human bronchial epithelial cells. , 2001, The European respiratory journal.
[103] R. Zuwallack,et al. Salmeterol plus theophylline combination therapy in the treatment of COPD. , 2001, Chest.
[104] L. Fabbri,et al. The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics. , 2001, The Journal of clinical investigation.
[105] Vernon M. Chinchilli,et al. Long-Acting β2-Agonist Monotherapy vs Continued Therapy With Inhaled Corticosteroids in Patients With Persistent Asthma: A Randomized Controlled Trial , 2001 .
[106] E. Israel,et al. Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: a randomized controlled trial. , 2001, JAMA.
[107] R. Aalbers,et al. Compliance with inhaled glucocorticoids and concomitant use of long-acting beta2-agonists. , 2001, Respiratory medicine.
[108] L. Fabbri,et al. Cellular and structural bases of chronic obstructive pulmonary disease. , 2001, American journal of respiratory and critical care medicine.
[109] J. Bousquet,et al. Effects of glucocorticoids on endogenous and transcellular metabolism of eicosanoids in asthma. , 2001, The Journal of allergy and clinical immunology.
[110] C. Baum,et al. Malnutrition in chronic obstructive pulmonary disease: adding insult to injury. , 2001, AACN clinical issues.
[111] S. Laufer,et al. Anti-inflammatory drugs: new multitarget compounds to face an old problem. The dual inhibition concept. , 2001, Pharmacological research.
[112] M. De Salvo,et al. In patients with COPD, treatment with a combination of formoterol and ipratropium is more effective than a combination of salbutamol and ipratropium : a 3-week, randomized, double-blind, within-patient, multicenter study. , 2001, Chest.
[113] R. Zuwallack,et al. Use of a Long-acting Inhaled β2-Adrenergic Agonist, Salmeterol Xinafoate, in Patients with Chronic Obstructive Pulmonary Disease , 2001 .
[114] M. Tamm,et al. Increased frequency of Chlamydia pneumoniae antibodies in patients with asthma. , 2001, American journal of respiratory and critical care medicine.
[115] N. Strenzke,et al. Effect of chloride channel blockers on anti-IgE-stimulated histamine and IL-4/IL-13 release from human basophils , 2001, Inflammation Research.
[116] B. Lipworth,et al. Evaluation of salmeterol or montelukast as second-line therapy for asthma not controlled with inhaled corticosteroids. , 2001, Chest.
[117] I. Adcock,et al. Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages. , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[118] R. Egan,et al. Th2 cytokines and asthma — The role of interleukin-5 in allergic eosinophilic disease , 2001, Respiratory research.
[119] M. Sanak,et al. Leukotriene C4 synthase polymorphism and aspirin-induced asthma. , 2001, The Journal of allergy and clinical immunology.
[120] H. Magnussen,et al. Effect of inhaled ciclesonide on airway responsiveness to inhaled AMP, the composition of induced sputum and exhaled nitric oxide in patients with mild asthma. , 2001, Pulmonary pharmacology & therapeutics.
[121] L. Boulet,et al. Effect of salmeterol on allergen‐induced airway inflammation in mild allergic asthma , 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[122] E. Raz,et al. DNA‐based immunotherapeutics for the treatment of allergic disease , 2001, Immunological reviews.
[123] K. R. Anderson,et al. Anti-inflammatory and lung function effects of montelukast in asthmatic volunteers exposed to sulfur dioxide. , 2001, Chest.
[124] A. Knox,et al. Regulation of TNF‐α‐induced eotaxin release from cultured human airway smooth muscle cells by β2‐agonists and corticosteroids , 2001 .
[125] P. Cullinan,et al. Cyclosporin as an oral corticosteroid sparing agent in stable asthma. , 2000, The Cochrane database of systematic reviews.
[126] Blair Jarvis,et al. Inhaled Salmeterol , 2001, Drugs & aging.
[127] P. Barnes,et al. Chronic obstructive pulmonary disease. , 2000, The New England journal of medicine.
[128] Stephen T Holgate,et al. Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response , 2000, The Lancet.
[129] K. Chung,et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response , 2000, The Lancet.
[130] P. Rutgeerts,et al. Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease , 2000 .
[131] P. Rutgeerts,et al. Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease. Crohn's Disease IL-10 Cooperative Study Group. , 2000, Gastroenterology.
[132] P. Howarth,et al. Persistent airway T-lymphocyte activation in chronic corticosteroid-treated symptomatic asthma. , 2000, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
[133] M. Cazzola,et al. Additive effects of salmeterol and fluticasone or theophylline in COPD. , 2000, Chest.
[134] E. Kerwin,et al. Fluticasone propionate/salmeterol combination provides more effective asthma control than low-dose inhaled corticosteroid plus montelukast. , 2000, The Journal of allergy and clinical immunology.
[135] O. Civelli,et al. Molecular cloning and characterization of a second human cysteinyl leukotriene receptor: discovery of a subtype selective agonist. , 2000, Molecular pharmacology.
[136] J C van der Wouden,et al. Inhaled disodium cromoglycate (DSCG) as maintenance therapy in children with asthma: a systematic review , 2000, Thorax.
[137] N Franklin Adkinson,et al. Long-term effects of budesonide or nedocromil in children with asthma. , 2000, The New England journal of medicine.
[138] R. Martin,et al. Substance P and its receptor neurokinin 1 expression in asthmatic airways. , 2000, The Journal of allergy and clinical immunology.
[139] D. D'Ambrosio,et al. Regulation of helper T cell differentiation and recruitment in airway inflammation. , 2000, American journal of respiratory and critical care medicine.
[140] A. Kay,et al. Attenuation of the allergen-induced late asthmatic reaction by cyclosporin A is associated with inhibition of bronchial eosinophils, interleukin-5, granulocyte macrophage colony-stimulating factor, and eotaxin. , 2000, American journal of respiratory and critical care medicine.
[141] M. Robuschi,et al. Inhaled transmembrane ion transport modulators and non-steroidal anti-inflammatory drugs in asthma , 2000, Thorax.
[142] B. Lipworth,et al. Effects of once-daily formoterol and budesonide given alone or in combination on surrogate inflammatory markers in asthmatic adults. , 2000, Chest.
[143] K. Chung,et al. Balance of matrix metalloprotease-9 and tissue inhibitor of metalloprotease-1 from alveolar macrophages in cigarette smokers. Regulation by interleukin-10. , 2000, American journal of respiratory and critical care medicine.
[144] Jilly F. Evans,et al. Characterization of the Human Cysteinyl Leukotriene 2 Receptor* , 2000, The Journal of Biological Chemistry.
[145] I. Adcock,et al. Glucocorticoid Receptor Recruitment of Histone Deacetylase 2 Inhibits Interleukin-1β-Induced Histone H4 Acetylation on Lysines 8 and 12 , 2000, Molecular and Cellular Biology.
[146] M. Sanak,et al. Enhanced expression of the leukotriene C(4) synthase due to overactive transcription of an allelic variant associated with aspirin-intolerant asthma. , 2000, American journal of respiratory cell and molecular biology.
[147] W. Busse,et al. Inhaled budesonide decreases airway inflammatory response to allergen. , 2000, American journal of respiratory and critical care medicine.
[148] F. Blasi,et al. Immunohistochemical staining for Chlamydia pneumoniae is increased in lung tissue from subjects with chronic obstructive pulmonary disease. , 2000, American journal of respiratory and critical care medicine.
[149] E. R. Mcfadden,et al. Comparative effects of long-acting beta2-agonists, leukotriene receptor antagonists, and a 5-lipoxygenase inhibitor on exercise-induced asthma. , 2000, The Journal of allergy and clinical immunology.
[150] B. Lipworth,et al. Functional antagonism with formoterol and salmeterol in asthmatic patients expressing the homozygous glycine-16 beta(2)-adrenoceptor polymorphism. , 2000, Chest.
[151] D. Theegarten,et al. The role of chlamydia in the pathogenesis of pulmonary emphysema , 2000, Virchows Archiv.
[152] K. Kelly,et al. Nedocromil sodium versus sodium cromoglycate for preventing exercise-induced bronchoconstriction , 2000 .
[153] E. Tagaya,et al. Effect of suplatast tosilate, a Th2 cytokine inhibitor, on steroid-dependent asthma: a double-blind randomised study , 2000, The Lancet.
[154] P. O'Byrne,et al. Protective effects of fluticasone on allergen-induced airway responses and sputum inflammatory markers. , 2000, Canadian respiratory journal.
[155] R. Egan,et al. Control of IL-5 production by human helper T cells as a treatment for eosinophilic inflammation: comparison of in vitro and in vivo effects between selective and nonselective cytokine synthesis inhibitors. , 2000, The Journal of allergy and clinical immunology.
[156] J. Drazen,et al. 5' flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States. , 2000, The Journal of allergy and clinical immunology.
[157] I. Adcock,et al. Molecular mechanisms of glucocorticosteroid actions. , 2000, Pulmonary pharmacology & therapeutics.
[158] S. Shrewsbury,et al. Meta-analysis of increased dose of inhaled steroid or addition of salmeterol in symptomatic asthma (MIASMA) , 2000, BMJ : British Medical Journal.
[159] S. Spencer,et al. Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial , 2000, BMJ : British Medical Journal.
[160] H. Simon,et al. Treatment with IFN-a in corticosteroid-unresponsiveasthma , 2000 .
[161] S. Sethi. Bacterial infection and the pathogenesis of COPD. , 2000, Chest.
[162] M. Sears,et al. Chlamydia pneumoniae serological status is not associated with asthma in children or young adults. , 2000, International journal of epidemiology.
[163] A. Knox,et al. Synergistic Inhibition by β2-Agonists and Corticosteroids on Tumor Necrosis Factor- α –Induced Interleukin-8 Release from Cultured Human Airway Smooth-Muscle Cells , 2000 .
[164] R. Pauwels,et al. A long-term study of the antiinflammatory effect of low-dose budesonide plus formoterol versus high-dose budesonide in asthma. , 2000, American journal of respiratory and critical care medicine.
[165] G. Anderson,et al. Interactions between corticosteroids and beta-adrenergic agonists in asthma disease induction, progression, and exacerbation. , 2000, American journal of respiratory and critical care medicine.
[166] R. Djukanović,et al. Low-dose methotrexate treatment in severe glucocorticoid-dependent asthma: effect on mucosal inflammation and in vitro sensitivity to glucocorticoids of mitogen-induced T-cell proliferation. , 2000, The European respiratory journal.
[167] Barnes Pj. Inhaled corticosteroids are not beneficial in chronic obstructive pulmonary disease. , 2000 .
[168] D. Strachan,et al. Chlamydia pneumoniae serology, lung function decline, and treatment for respiratory disease. , 2000, American journal of respiratory and critical care medicine.
[169] H. Nelson,et al. Lack of correlation between Chlamydia pneumoniae antibody titers and adult-onset asthma. , 2000, The Journal of allergy and clinical immunology.
[170] P. Barnes,et al. Mechanisms in COPD: differences from asthma. , 2000, Chest.
[171] E. Bronsky,et al. Oral Montelukast Compared with Inhaled Salmeterol To Prevent Exercise-Induced Bronchoconstriction , 2000, Annals of Internal Medicine.
[172] H. Davies,et al. Methotrexate as a steroid sparing agent for asthma in adults. , 1998, The Cochrane database of systematic reviews.
[173] T. Shimizu,et al. Leukotriene-B4 receptor and signal transduction. , 2000, Ernst Schering Research Foundation workshop.
[174] I. Danta,et al. Effect of an inhaled glucocorticosteroid on airway mucosal blood flow in mild asthma. , 2000, American journal of respiratory and critical care medicine.
[175] P. O'Byrne,et al. The effects of inhaled budesonide on circulating eosinophil progenitors and their expression of cytokines after allergen challenge in subjects with atopic asthma. , 2000, American journal of respiratory and critical care medicine.
[176] J. Fahy,et al. Low- and high-dose fluticasone propionate in asthma; effects during and after treatment. , 2000, The European respiratory journal.
[177] B. Lipworth,et al. A high dose of albuterol does not overcome bronchoprotective subsensitivity in asthmatic subjects receiving regular salmeterol or formoterol. , 2011, The Journal of allergy and clinical immunology.
[178] F. Annunziato,et al. Phosphorothioate oligodeoxynucleotides promote the in vitro development of human allergen-specific CD4+ T cells into Th1 effectors. , 1999, Journal of immunology.
[179] L. Borish,et al. Interleukin-4 receptor in moderate atopic asthma. A phase I/II randomized, placebo-controlled trial. , 1999, American journal of respiratory and critical care medicine.
[180] E. Nussbaum,et al. Immunosuppressive and cytotoxic effects of furosemide on human peripheral blood mononuclear cells. , 1999, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
[181] B. Lipworth,et al. Lack of subsensitivity to albuterol after treatment with salmeterol in patients with asthma. , 1999, American journal of respiratory and critical care medicine.
[182] P. Barnes. Therapeutic strategies for allergic diseases , 1999, Nature.
[183] N. Bodor,et al. Recent advances in retrometabolic design approaches. , 1999, Journal of controlled release : official journal of the Controlled Release Society.
[184] F. Thien,et al. An antiinflammatory effect of salmeterol, a long-acting beta(2) agonist, assessed in airway biopsies and bronchoalveolar lavage in asthma. , 1999, American journal of respiratory and critical care medicine.
[185] W. Maziak,et al. Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease. , 1999, American journal of respiratory and critical care medicine.
[186] J. Carlstedt-Duke. Glucocorticoid Receptor β: View II , 1999, Trends in Endocrinology & Metabolism.
[187] G. Chrousos,et al. Glucocorticoid Receptor β: View I , 1999, Trends in Endocrinology & Metabolism.
[188] A. Chuchalin,et al. Montelukast versus salmeterol in patients with asthma and exercise-induced bronchoconstriction. Montelukast/Salmeterol Exercise Study Group. , 1999, The Journal of allergy and clinical immunology.
[189] K. Chung,et al. Cytokines in asthma , 1999, Thorax.
[190] D. Postma,et al. Exacerbations of asthma: a descriptive study of 425 severe exacerbations. The FACET International Study Group. , 1999, American journal of respiratory and critical care medicine.
[191] K. Satoh,et al. Interleukin-10 level in sputum is reduced in bronchial asthma, COPD and in smokers. , 1999, The European respiratory journal.
[192] J. Lötvall,et al. Comparison of the relative efficacy of formoterol and salmeterol in asthmatic patients. , 1999, American journal of respiratory and critical care medicine.
[193] L. Boulet,et al. Montelukast reduces airway eosinophilic inflammation in asthma: a randomized, controlled trial. , 1999, The European respiratory journal.
[194] S. Holgate,et al. IL-5 increases expression of 5-lipoxygenase-activating protein and translocates 5-lipoxygenase to the nucleus in human blood eosinophils. , 1999, Journal of immunology.
[195] P. Sterk,et al. Lung function and sputum characteristics of patients with severe asthma during an induced exacerbation by double-blind steroid withdrawal. , 1999, American journal of respiratory and critical care medicine.
[196] P. O'Byrne,et al. An inhaled corticosteroid, budesonide, reduces baseline but not allergen-induced increases in bone marrow inflammatory cell progenitors in asthmatic subjects. , 1999, American journal of respiratory and critical care medicine.
[197] A. Zwinderman,et al. Effect of inhaled steroids on airway hyperresponsiveness, sputum eosinophils, and exhaled nitric oxide levels in patients with asthma , 1999, Thorax.
[198] K. Umesono,et al. Redox-dependent Regulation of Nuclear Import of the Glucocorticoid Receptor* , 1999, The Journal of Biological Chemistry.
[199] Leinonen,et al. Asthma, atopy and Chlamydia pneumoniae antibodies in adults , 1999, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[200] J. Vandenbroucke,et al. Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment. The AMPUL Study Group. , 1999, American journal of respiratory and critical care medicine.
[201] F. Thien,et al. Vascularity in asthmatic airways: relation to inhaled steroid dose. , 1999, Thorax.
[202] Lynn Wei,et al. Oral Montelukast, Inhaled Beclomethasone, and Placebo for Chronic Asthma , 1999, Annals of Internal Medicine.
[203] T. Mosmann,et al. Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells. , 1999, Journal of immunology.
[204] D. Umetsu,et al. The kinetics of change in cytokine production by CD4 T cells during conventional allergen immunotherapy. , 1999, The Journal of allergy and clinical immunology.
[205] J. Drazen,et al. Genetic Determinants of 5–Lipoxygenase Transcription , 1999, International Archives of Allergy and Immunology.
[206] E. Israel,et al. Correction: Treatment of Asthma with Drugs Modifying the Leukotriene Pathway. , 1999, The New England journal of medicine.
[207] O. Eickelberg,et al. Ligand-independent Activation of the Glucocorticoid Receptor by β2-Adrenergic Receptor Agonists in Primary Human Lung Fibroblasts and Vascular Smooth Muscle Cells* , 1999, The Journal of Biological Chemistry.
[208] A. Zwinderman,et al. The effect of montelukast (MK‐0476), a cysteinyl leukotriene receptor antagonist, on allergen‐induced airway responses and sputum cell counts in asthma , 1999, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[209] P. Godard,et al. A comparison of two long-acting P-agonists, oral bambuterol and inhaled salmeterol, in the treatment of moderate to severe asthmatic patients with nocturnal symptoms , 2004 .
[210] P. Howarth,et al. The effects of regular inhaled formoterol, budesonide, and placebo on mucosal inflammation and clinical indices in mild asthma. , 1999, American journal of respiratory and critical care medicine.
[211] I. Pavord,et al. Prednisone-dependent asthma: inflammatory indices in induced sputum. , 1999, The European respiratory journal.
[212] Mutations in the human 5-lipoxygenase gene , 1999, Clinical reviews in allergy & immunology.
[213] N. Tzanakis,et al. Diagnosis and treatment of chronic obstructive pulmonary disease: evidence-based medicine. , 1998, Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace.
[214] B. Lindmark. Cardiac risks with β agonists , 1998, Thorax.
[215] K. Chung,et al. Inflammatory mediators of asthma: an update. , 1998, Pharmacological reviews.
[216] J. Drazen. Leukotrienes as mediators of airway obstruction. , 1998, American journal of respiratory and critical care medicine.
[217] I. Adcock,et al. Activation and localization of transcription factor, nuclear factor-kappaB, in asthma. , 1998, American journal of respiratory and critical care medicine.
[218] J. Jenne. Can oral β2 agonists cause heart failure? , 1998, The Lancet.
[219] J. Oates,et al. Salmeterol prevents aspirin-induced attacks of asthma and interferes with eicosanoid metabolism. , 1998, American journal of respiratory and critical care medicine.
[220] Teruo Sakamoto,et al. Effect of the leukotriene receptor antagonist pranlukast on cellular infiltration in the bronchial mucosa of patients with asthma , 1998, Thorax.
[221] R. Martin,et al. Detection of Mycoplasma pneumoniae in the airways of adults with chronic asthma. , 1998, American journal of respiratory and critical care medicine.
[222] M. Sears,et al. Potential masking effects of salmeterol on airway inflammation in asthma. , 1998, American journal of respiratory and critical care medicine.
[223] P. Sterk,et al. Effects of theophylline on tolerance to the bronchoprotective actions of salmeterol in asthmatics in vivo. , 1998, American journal of respiratory and critical care medicine.
[224] G. Town,et al. Asthma control during long term treatment with regular inhaled salbutamol and salmeterol , 1998, Thorax.
[225] J. Drazen,et al. Egr-1 and Sp1 interact functionally with the 5-lipoxygenase promoter and its naturally occurring mutants. , 1998, American journal of respiratory cell and molecular biology.
[226] E. R. Mcfadden,et al. Effect of long-term salmeterol treatment on exercise-induced asthma. , 1998, The New England journal of medicine.
[227] P. Barnes,et al. Haplotype associated with low interleukin-10 production in patients with severe asthma , 1998, The Lancet.
[228] S. Szefler,et al. Fluticasone propionate results in improved glucocorticoid receptor binding affinity and reduced oral glucocorticoid requirements in severe asthma. , 1998, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
[229] P. Clementsen,et al. Chlamydia pneumoniae and possible relationship to asthma , 1998, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
[230] N. Dunn,et al. Risk of non-fatal cardiac failure and ischaemic heart disease with long acting β2 agonists , 1998, Thorax.
[231] R. Dockhorn,et al. Montelukast, a once-daily leukotriene receptor antagonist, in the treatment of chronic asthma: a multicenter, randomized, double-blind trial. Montelukast Clinical Research Study Group. , 1998, Archives of internal medicine.
[232] H. Boushey,et al. Effect of low-dose beclomethasone dipropionate on asthma control and airway inflammation. , 1998, The European respiratory journal.
[233] M. Karin. New Twists in Gene Regulation by Glucocorticoid Receptor: Is DNA Binding Dispensable? , 1998, Cell.
[234] R. Fuller,et al. An overview of nine clinical trials of salmeterol in an asthmatic population. , 1998, Respiratory medicine.
[235] P. Paggiaro,et al. Multicentre randomised placebo-controlled trial of inhaled fluticasone propionate in patients with chronic obstructive pulmonary disease , 1998, The Lancet.
[236] S. Wenzel,et al. New approaches to anti-inflammatory therapy for asthma. , 1998, The American journal of medicine.
[237] S. Holgate,et al. Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma. , 1998, The Journal of clinical investigation.
[238] K. Wilner,et al. Pharmacokinetics and pharmacodynamics of the leukotriene B4 receptor antagonist CP-105,696 in man following single oral administration. , 1998, British journal of clinical pharmacology.
[239] B. Davies,et al. The efficacy and safety of salmeterol compared to theophylline: meta-analysis of nine controlled studies. , 1998, Respiratory medicine.
[240] R. Panettieri,et al. Effects of LTD4 on human airway smooth muscle cell proliferation, matrix expression, and contraction In vitro: differential sensitivity to cysteinyl leukotriene receptor antagonists. , 1998, American journal of respiratory cell and molecular biology.
[241] K. Chung,et al. Inhaled corticosteroids increase interleukin-10 but reduce macrophage inflammatory protein-1alpha, granulocyte-macrophage colony-stimulating factor, and interferon-gamma release from alveolar macrophages in asthma. , 1998, American journal of respiratory and critical care medicine.
[242] R. Sakalauskas,et al. Comparison of addition of theophylline to inhaled steroid with doubling of the dose of inhaled steroid in asthma. , 1997, The European respiratory journal.
[243] K. Chung,et al. A comparison of low-dose inhaled budesonide plus theophylline and high-dose inhaled budesonide for moderate asthma. , 1997, The New England journal of medicine.
[244] D. Postma,et al. Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. , 1997, The New England journal of medicine.
[245] Robert J. Lefkowitz,et al. Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A , 1997, Nature.
[246] F. Blasi,et al. Failure to detect the presence of Chlamydia pneumoniae in sarcoid pathology specimens. , 1997, The European respiratory journal.
[247] R. Snijder,et al. Diagnosis of Chlamydia pneumoniae infection in patients with chronic obstructive pulmonary disease by micro-immunofluorescence and ELISA. , 1997, Journal of medical microbiology.
[248] S. Wenzel,et al. Bronchoscopic evaluation of severe asthma. Persistent inflammation associated with high dose glucocorticoids. , 1997, American journal of respiratory and critical care medicine.
[249] D. McDonald,et al. Upregulation of substance P receptors in angiogenesis associated with chronic airway inflammation in rats. , 1997, The American journal of physiology.
[250] A. Pesci,et al. Inhaled beclomethasone dipropionate downregulates CD4 and CD8 T-lymphocyte activation in peripheral blood of patients with asthma. , 1997, The Journal of allergy and clinical immunology.
[251] A Bast,et al. Oxidative stress in chronic obstructive pulmonary disease. Oxidative Stress Study Group. , 1997, American journal of respiratory and critical care medicine.
[252] D. Yates,et al. Effect of short- and long-acting inhaled beta2-agonists on exhaled nitric oxide in asthmatic patients. , 1997, The European respiratory journal.
[253] A. Casalini,et al. Effect of short-term treatment with low-dose inhaled fluticasone propionate on airway inflammation and remodeling in mild asthma: a placebo-controlled study. , 1997, American journal of respiratory and critical care medicine.
[254] J. Baker,et al. Dexamethasone increases expression of 5-lipoxygenase and its activating protein in human monocytes and THP-1 cells. , 1997, European journal of biochemistry.
[255] J. Bousquet,et al. Corticosteroid reversibility in COPD is related to features of asthma. , 1997, American journal of respiratory and critical care medicine.
[256] A. Sousa,et al. Effect of inhaled glucocorticoids on IL-1 beta and IL-1 receptor antagonist (IL-1 ra) expression in asthmatic bronchial epithelium. , 1997, Thorax.
[257] S. Wenzel,et al. The effect of salmeterol on nocturnal symptoms, airway function, and inflammation in asthma. , 1997, Chest.
[258] S. Durham,et al. Effect of cyclosporin A on the allergen-induced late asthmatic reaction. , 1997, Thorax.
[259] M. Leinonen,et al. Chlamydia pneumoniae infection in patients with chronic obstructive pulmonary disease , 1997, Epidemiology and Infection.
[260] E. Silverman,et al. Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription. , 1997, The Journal of clinical investigation.
[261] P. Barnes,et al. Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD. , 1997, American journal of respiratory and critical care medicine.
[262] S. Anderson,et al. Effect of inhaled frusemide and oral indomethacin on the airway response to hypertonic saline challenge in asthmatic subjects. , 1997, Thorax.
[263] B. Celli. ATS standards for the optimal management of chronic obstructive pulmonary disease. , 1997, Respirology.
[264] M. Beato,et al. Interaction of steroid hormone receptors with the transcription initiation complex. , 1996, Endocrine reviews.
[265] D. Yates,et al. An inhaled glucocorticoid does not prevent tolerance to the bronchoprotective effect of a long-acting inhaled beta 2-agonist. , 1996, American journal of respiratory and critical care medicine.
[266] P. Barnes,et al. Effect of a leukotriene B4 receptor antagonist, LY293111, on allergen induced responses in asthma. , 1996, Thorax.
[267] L. Dubé,et al. Acute and chronic effects of a 5-lipoxygenase inhibitor in asthma: A 6-month randomized multicenter trial , 1996 .
[268] J. Baseman,et al. Interplay between mycoplasma surface proteins, airway cells, and the protean manifestations of mycoplasma-mediated human infections. , 1996, American journal of respiratory and critical care medicine.
[269] C. Corrigan,et al. Glucocorticoid resistant asthma: T-lymphocyte steroid metabolism and sensitivity to glucocorticoids and immunosuppressive agents. , 1996, The European respiratory journal.
[270] R. Pauwels,et al. GLOBAL STRATEGY FOR ASTHMA MANAGEMENT AND PREVENTION , 1996 .
[271] I. Adcock,et al. Glucocorticoid receptor localization in normal and asthmatic lung. , 1996, American journal of respiratory and critical care medicine.
[272] E. Gelfand,et al. Nebulized IFN-gamma inhibits the development of secondary allergic responses in mice. , 1996, Journal of immunology.
[273] R. Djukanović,et al. Effects of theophylline on inflammatory cells and cytokines in asthmatic subjects: a placebo-controlled parallel group study. , 1996, The European respiratory journal.
[274] J. V. van Noord,et al. Salmeterol versus formoterol in patients with moderately severe asthma: onset and duration of action. , 1996, The European respiratory journal.
[275] S T Holgate,et al. Leukotriene antagonists and synthesis inhibitors: new directions in asthma therapy. , 1996, The Journal of allergy and clinical immunology.
[276] N. Barnes,et al. Can clinical response to cyclosporin in chronic severe asthma be predicted by an in vitro T-lymphocyte proliferation assay? , 1996, The European respiratory journal.
[277] S. Wenzel,et al. Theophylline: potential antiinflammatory effects in nocturnal asthma. , 1996, The Journal of allergy and clinical immunology.
[278] S. Durham,et al. Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-gamma. , 1996, The Journal of allergy and clinical immunology.
[279] A. Norris. Pharmacology of sodium cromoglycate , 1996, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[280] L. Fabbri,et al. Methotrexate in the treatment of systemic glucocorticoid-dependent severe persistent asthma: a word of caution. , 1996, Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace.
[281] D. McDonald,et al. Sensory denervation by neonatal capsaicin treatment exacerbates Mycoplasma pulmonis infection in rat airways. , 1996, The American journal of physiology.
[282] N. Barnes,et al. Double-blind, placebo-controlled study of cyclosporin A as a corticosteroid-sparing agent in corticosteroid-dependent asthma. , 1996, American journal of respiratory and critical care medicine.
[283] P. Barnes,et al. Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma. , 1996, American journal of respiratory and critical care medicine.
[284] S. Durham,et al. Prednisolone treatment in asthma. Reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa. , 1996, American journal of respiratory and critical care medicine.
[285] J. Murray,et al. A controlled trial of the effect of the 5-lipoxygenase inhibitor, zileuton, on lung inflammation produced by segmental antigen challenge in human beings. , 1996, The Journal of allergy and clinical immunology.
[286] C. Janson,et al. Serology of chlamydia in relation to asthma and bronchial hyperresponsiveness. , 1996, Scandinavian journal of infectious diseases.
[287] D. Yates,et al. Inhaled glucocorticoids decrease nitric oxide in exhaled air of asthmatic patients. , 1996, American journal of respiratory and critical care medicine.
[288] Joseph A. DiDonato,et al. Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis , 1995, Science.
[289] A. Baldwin,et al. Role of Transcriptional Activation of IκBα in Mediation of Immunosuppression by Glucocorticoids , 1995, Science.
[290] D. Mungan,et al. Cyclosporin in steroid dependent asthma. , 1995, Allergologia et immunopathologia.
[291] P. Barnes,et al. Beta-adrenergic receptors and their regulation. , 1995, American journal of respiratory and critical care medicine.
[292] K. Sladek,et al. Treatment of steroid-dependent bronchial asthma with cyclosporin. , 1995, The European respiratory journal.
[293] T. Fukuda,et al. Cyclosporine A reduces T lymphocyte activity and improves airway hyperresponsiveness in corticosteroid-dependent chronic severe asthma. , 1995, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
[294] C. Page,et al. Theophylline and selective phosphodiesterase inhibitors as anti-inflammatory drugs in the treatment of bronchial asthma. , 1995, The European respiratory journal.
[295] K. Chung,et al. Immunomodulation by theophylline in asthma. Demonstration by withdrawal of therapy. , 1995, American journal of respiratory and critical care medicine.
[296] R. Djukanović,et al. The effects of theophylline on mucosal inflammation in asthmatic airways: biopsy results. , 1995, The European respiratory journal.
[297] G. Cox,et al. Glucocorticoid treatment inhibits apoptosis in human neutrophils. Separation of survival and activation outcomes. , 1995, Journal of immunology.
[298] J. Virchow,et al. T cells and cytokines in bronchoalveolar lavage fluid after segmental allergen provocation in atopic asthma. , 1995, American journal of respiratory and critical care medicine.
[299] N. Barnes,et al. Clinical response to cyclosporin in chronic severe asthma is associated with reduction in serum soluble interleukin-2 receptor concentrations. , 1995, The European respiratory journal.
[300] P. Barnes,et al. Inhaled glucocorticoids for asthma. , 1995, The New England journal of medicine.
[301] O. Kaminuma,et al. IL-5 production by CD4+ T cells of asthmatic patients is suppressed by glucocorticoids and the immunosuppressants FK506 and cyclosporin A. , 1995, International immunology.
[302] C. Chavis,et al. Enhancement of leukotriene A4 biosynthesis in neutrophils from patients with rheumatoid arthritis after a single glucocorticoid dose. , 1995, Biochemical pharmacology.
[303] Richard J Martin,et al. The effects of nebulized recombinant interferon-γ in asthmatic airways , 1995 .
[304] R. Schleimer,et al. The effects of glucocorticoids on human eosinophils. , 1994, The Journal of allergy and clinical immunology.
[305] D. McDonald,et al. Dexamethasone and oxytetracycline reverse the potentiation of neurogenic inflammation in airways of rats with Mycoplasma pulmonis infection. , 1994, American journal of respiratory and critical care medicine.
[306] D. Hendrick,et al. Effect of eight weeks of treatment with salmeterol on bronchoalveolar lavage inflammatory indices in asthmatics. , 1994, American journal of respiratory and critical care medicine.
[307] T. Haahtela,et al. Effects of reducing or discontinuing inhaled budesonide in patients with mild asthma. , 1994, The New England journal of medicine.
[308] Hahn Dl. Infection as a cause of asthma. , 1994 .
[309] O. Kaminuma,et al. Regulation of interleukin-5 production by peripheral blood mononuclear cells from atopic patients with FK506, cyclosporin A and glucocorticoid. , 1994, International archives of allergy and immunology.
[310] K. Oizumi,et al. Association of Mycoplasma pneumoniae antigen with initial onset of bronchial asthma. , 1994, American journal of respiratory and critical care medicine.
[311] P. Howarth,et al. Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. , 1994, American journal of respiratory cell and molecular biology.
[312] C. Page,et al. Anti-inflammatory effects of low-dose oral theophylline in atopic asthma , 1994, The Lancet.
[313] J. Oates,et al. Effect of oral prednisone on airway inflammatory mediators in atopic asthma. , 1994, American journal of respiratory and critical care medicine.
[314] S. McColl,et al. Granulocyte/macrophage colony-stimulating factor stimulates the expression of the 5-lipoxygenase-activating protein (FLAP) in human neutrophils , 1994, The Journal of experimental medicine.
[315] H. Taniguchi,et al. Reduction of the severity of bronchial hyperresponsiveness by the novel leukotriene antagonist 4-oxo-8-[4-(4-phenyl-butoxy)benzoylamino]-2- (tetrazol-5-yl)-4H-1-benzopyran hemihydrate. , 1994, Arzneimittel-Forschung.
[316] G. Chiappara,et al. Theophylline suppresses the release of tumour necrosis factor-alpha by blood monocytes and alveolar macrophages. , 1994, The European respiratory journal.
[317] B. Li,et al. The effect of dexamethasone, cyclosporine, and rapamycin on T-lymphocyte proliferation in vitro: comparison of cells from patients with glucocorticoid-sensitive and glucocorticoid-resistant chronic asthma. , 1994, The Journal of allergy and clinical immunology.
[318] P. Howarth,et al. Inhaled beclomethasone dipropionate downregulates airway lymphocyte activation in atopic asthma. , 1994, American journal of respiratory and critical care medicine.
[319] R. de Caterina,et al. Macrophage-specific eicosanoid synthesis inhibition and lipocortin-1 induction by glucocorticoids. , 1993, Journal of applied physiology.
[320] R. M. Refini,et al. Potentiation of the antireactive, antiasthmatic effect of inhaled furosemide by inhaled lysine acetylsalicylate , 1993, Allergy.
[321] P. Barnes,et al. Differential down-regulation of pulmonary β1- and β2-adrenoceptor messenger RNA with prolonged in vivo infusion of isoprenaline , 1993 .
[322] H. Magnussen,et al. Effects of theophylline withdrawal in severe chronic obstructive pulmonary disease. , 1993, Chest.
[323] C. Page,et al. Theophylline--an immunomodulatory role in asthma? , 1993, The American review of respiratory disease.
[324] K. Chung,et al. Effect of inhaled corticosteroids on peripheral blood eosinophil counts and density profiles in asthma. , 1993, The Journal of allergy and clinical immunology.
[325] M. Fujimura,et al. Effect of a leukotriene antagonist, ONO-1078, on bronchial hyperresponsiveness in patients with asthma. , 1993, Respiratory medicine.
[326] G. Anderson. Long acting inhaled beta-adrenoceptor agonists the comparative pharmacology of formoterol and salmeterol. , 1993, Agents and actions. Supplements.
[327] C. Romanin,et al. Potent block of Cl- channels by antiallergic drugs. , 1992, Biochemical and biophysical research communications.
[328] J. Kemp,et al. A comparison of salmeterol with albuterol in the treatment of mild-to-moderate asthma. , 1992, The New England journal of medicine.
[329] W. R. Beam,et al. Detection of alveolar macrophage-derived IL-1 beta in asthma. Inhibition with corticosteroids. , 1992, Journal of immunology.
[330] A. Zwinderman,et al. Long-term effects of a long-acting beta 2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma. , 1992, The New England journal of medicine.
[331] T. Feizi,et al. Immunoelectron microscopic studies reveal differences in distribution of sialo-oligosaccharide receptors for Mycoplasma pneumoniae on the epithelium of human and hamster bronchi , 1992, Infection and immunity.
[332] R. Shaw,et al. Dexamethasone-induced increase in platelet-derived growth factor (B) mRNA in human alveolar macrophages and myelomonocytic HL60 macrophage-like cells. , 1992, American journal of respiratory cell and molecular biology.
[333] T. Haahtela,et al. A comparative study of the effects of an inhaled corticosteroid, budesonide, and a beta 2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: a randomized, double-blind, parallel-group controlled trial. , 1992, The Journal of allergy and clinical immunology.
[334] P. Howarth,et al. Early changes in T lymphocytes recovered by bronchoalveolar lavage after local allergen challenge of asthmatic airways. , 1992, The American review of respiratory disease.
[335] G. Guyatt,et al. A research method to induce and examine a mild exacerbation of asthma by withdrawal of inhaled corticosteroid , 1992, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[336] P. Jeffery,et al. Effects of treatment on airway inflammation and thickening of basement membrane reticular collagen in asthma. A quantitative light and electron microscopic study. , 1992, The American review of respiratory disease.
[337] P. Howarth,et al. Effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma. , 1992, The American review of respiratory disease.
[338] N. Barnes,et al. Trial of cyclosporin in corticosteroid-dependent chronic severe asthma , 1992, The Lancet.
[339] T. Martin,et al. Chlamydia pneumoniae, strain TWAR, infection in patients with chronic obstructive pulmonary disease. , 1991, The American review of respiratory disease.
[340] C. Romanin,et al. Immunologically activated chloride channels involved in degranulation of rat mucosal mast cells. , 1991, The EMBO journal.
[341] T. Haahtela,et al. Comparison of a beta 2-agonist, terbutaline, with an inhaled corticosteroid, budesonide, in newly detected asthma. , 1991, The New England journal of medicine.
[342] A. Tattersfield,et al. Time course of change in bronchial reactivity with an inhaled corticosteroid in asthma. , 1991, The American review of respiratory disease.
[343] R. Dixon,et al. Gene characterization and promoter analysis of the human 5-lipoxygenase-activating protein (FLAP). , 1991, The Journal of biological chemistry.
[344] H. Kita,et al. Regulation of Ig-induced eosinophil degranulation by adenosine 3',5'-cyclic monophosphate. , 1991, Journal of immunology.
[345] L. Fabbri,et al. Corticosteroid inhibition of airway microvascular leakage. , 1991, The American review of respiratory disease.
[346] E. Juniper,et al. Reduction of budesonide after a year of increased use: a randomized controlled trial to evaluate whether improvements in airway responsiveness and clinical asthma are maintained. , 1991, The Journal of allergy and clinical immunology.
[347] T. Out,et al. Respiratory membrane permeability and bronchial hyperreactivity in patients with stable asthma. Effects of therapy with inhaled steroids. , 1991, The American review of respiratory disease.
[348] A. Zwinderman,et al. The effect of inhaled corticosteroids on the maximal degree of airway narrowing to methacholine in asthmatic subjects. , 1991, The American review of respiratory disease.
[349] E. Juniper,et al. Long-term effects of budesonide on airway responsiveness and clinical asthma severity in inhaled steroid-dependent asthmatics. , 1990, The European respiratory journal.
[350] E. Juniper,et al. Effect of long-term treatment with an inhaled corticosteroid (budesonide) on airway hyperresponsiveness and clinical asthma in nonsteroid-dependent asthmatics. , 1990, The American review of respiratory disease.
[351] J. Oates,et al. Inhibition of eicosanoid biosynthesis by glucocorticoids in humans. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[352] P. Venge,et al. Inflammatory cells and eosinophilic activity in asthmatics investigated by bronchoalveolar lavage. The effects of antiasthmatic treatment with budesonide or terbutaline. , 1990, The American review of respiratory disease.
[353] M. Montminy,et al. Regulation of camp-inducible genes by creb , 1990, Trends in Neurosciences.
[354] H. Sasaki,et al. Direct inhibitory action of glucocorticoid on glycoconjugate secretion from airway submucosal glands. , 1990, The American review of respiratory disease.
[355] J. Shelhamer,et al. Mechanisms by which glucocorticosteroids inhibit secretion of mucus in asthmatic airways. , 1990, The American review of respiratory disease.
[356] P. Barnes,et al. Effect of corticosteroids on airway hyperresponsiveness. , 1990, The American review of respiratory disease.
[357] R. Dixon,et al. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis , 1990, Nature.
[358] S. Peters,et al. Arachidonic acid metabolism in normal human alveolar macrophages: stimulus specificity for mediator release and phospholipid metabolism, and pharmacologic modulation in vitro and in vivo. , 1990, American journal of respiratory cell and molecular biology.
[359] S. Peters,et al. An assessment of the effects of glucocorticoids on degranulation, chemotaxis, binding to vascular endothelium and formation of leukotriene B4 by purified human neutrophils. , 1989, The Journal of pharmacology and experimental therapeutics.
[360] K. Chung,et al. Effect of theophylline and adenosine on eosinophil function. , 1989, The American review of respiratory disease.
[361] P. Godard,et al. High doses of inhaled corticosteroids in unstable chronic asthma. A multicenter, double-blind, placebo-controlled study. , 1989, The American review of respiratory disease.
[362] M. Robuschi,et al. Inhaled frusemide is highly effective in preventing ultrasonically nebulised water bronchoconstriction. , 1989, Pulmonary pharmacology.
[363] M. Hollenberg,et al. Evaluation of the antiinflammatory and phospholipase-inhibitory activity of calpactin II/lipocortin I. , 1988, The Journal of clinical investigation.
[364] N. Johnson,et al. Effects of sodium cromoglycate and nedocromil sodium on histamine secretion from human lung mast cells. , 1988, Thorax.
[365] G. Canonica,et al. Theophylline and the immune response: in vitro and in vivo effects. , 1988, Clinical immunology and immunopathology.
[366] P. Ghezzi,et al. IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-gamma. , 1988, Journal of immunology.
[367] B. Weeke,et al. Fiberoptic bronchoscopy and bronchial mucosal biopsies in asthmatics undergoing long‐term high‐dose budesonide aerosol treatment , 1988, Allergy.
[368] C. Salome,et al. Inhaled corticosteroids reduce the severity of bronchial hyperresponsiveness in asthma but oral theophylline does not. , 1987, The American review of respiratory disease.
[369] L. Lichtenstein,et al. Selective inhibition of arachidonic acid metabolite release from human lung tissue by antiinflammatory steroids. , 1986, Journal of immunology.
[370] R. Naclerio,et al. The pharmacologic control of mediator release from human basophils and mast cells. , 1986, Respiration; international review of thoracic diseases.
[371] L. Rosenhall,et al. High Dose Inhaled Budesonide in the Treatment of Severe Steroid‐Dependent Asthmatics , 1985, Allergy.
[372] R. Pardi,et al. Theophylline induced non specific suppressor activity in human peripheral blood lymphocytes. , 1985, Journal of immunopharmacology.
[373] R. Naclerio,et al. IgE-mediated leukotriene release in vitro and in vivo. , 1984, Transactions of the Association of American Physicians.
[374] D. Cooper,et al. Mycoplasma pneumoniae: acute illness, antibiotics, and subsequent pulmonary function. , 1984, Archives of disease in childhood.
[375] O. Bruserud. The effect of theophyllamine on T-lymphocyte activation in vitro. , 1984, Clinical immunology and immunopathology.
[376] S. Peters,et al. Arachidonic acid metabolism in purified human lung mast cells. , 1984, Journal of immunology.
[377] S. Peters,et al. Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells. , 1983, The Journal of clinical investigation.
[378] H. Simpson,et al. Mycoplasma pneuminia infection. A follow-up study of 50 children with respiratory illness. , 1979, Archives of Disease in Childhood.
[379] C. Shim,et al. The effect of ethanol on the cough reflex. , 1973, Clinical science and molecular medicine.
[380] A. Rebuck,et al. STEROID‐SPARING EFFECT OF DISODIUM CROMOGLYCATE (“INTAL”) IN CHRONIC ASTHMA , 1969 .