Comparison of Pain between First and Second Operated Eyelids after Upper Eyelid Blepharoplasty

Purpose To evaluate and compare intraoperative pain during upper eyelid blepharoplasty (UEB) between on first and second operated eyelids. Methods In this cross-sectional observational study, the patients were divided into two groups, with group 1 representing 40 patients whose surgery was first started on the right and group 2 representing the other 40 patients who started surgery on the left first. UEB was performed to all patients by the same surgeon under the same and equal amount of local anesthesia. Degree of pain felt during surgery on first and second operated eyelid was evaluated with the visual analoge scale (VAS) and Wong-Baker Facial Pain Expression Scale (WBFPES) of all patients immediately after surgery and was compared using paired t-test. Results There were 20 female and 20 male patients in both groups. In group 1, the VAS value was 2.8 ± 1.5 and WBFPES value was 2.7 ± 1.6 UEB in the first operated eyelid; the VAS value was 4.1 ± 1.8 and WBFPES value was 3.9 ± 1.8 UEB in the second operated eyelid. A significant difference was found between pains felt during first and second operated eyelid UEB regarding VAS and WBFPES values in group 1 (p = 0.003 and p = 0.002, respectively). In group 2, the VAS value was 1.9 ± 1.0 and WBFPES value was 2.0 ± 1.0 UEB in the first operated eyelid; the VAS value was 3.0 ± 1.5 and WBFPES value was 2.8 ± 1.6 UEB in the second operated eyelid. A significant difference was found between pains felt during first operated and second operated eyelid UEB regarding VAS and WBFPES values in group 2 (p = 0.009 and p = 0.005, respectively). Conclusions To the best of our knowledge, this study is the first to evaluate which eyelid is more painful during surgery in UEB. Patients tend to feel more pain during surgery on the second operated eyelid. Therefore, surgeons should consider using local anesthetics with more volume or longer duration in the second operating eyelid in light of this information and patients should be given detailed information about pain.

[1]  Feng Zhang,et al.  Dynamic monocyte chemoattractant protein-1 level as predictors of perceived pain during first and second phacoemulsification eye surgeries in patients with bilateral cataract , 2021, BMC Ophthalmology.

[2]  Xianhui Gong,et al.  Substance P induces sympathetic immune response in the contralateral eye after the first eye cataract surgery in type 2 diabetic patients , 2020, BMC Ophthalmology.

[3]  B. Zee,et al.  Pain Perception of the First Eye versus the Second Eye during Phacoemulsification under Local Anesthesia for Patients Going through Cataract Surgery: A Systematic Review and Meta-Analysis , 2019, Journal of ophthalmology.

[4]  M. Struys,et al.  A randomised double-blinded crossover study comparing pain during anaesthetising the eyelids in upper blepharoplasty: First versus second eyelid and lidocaine versus prilocaine. , 2015, Journal of plastic, reconstructive & aesthetic surgery : JPRAS.

[5]  Xiangjia Zhu,et al.  Perceived Pain during Cataract Surgery with Topical Anesthesia: A Comparison between First-Eye and Second-Eye Surgery , 2015, Journal of ophthalmology.

[6]  F. Adatia,et al.  Documenting the subjective patient experience of first versus second cataract surgery , 2015, Journal of cataract and refractive surgery.

[7]  D. Holck,et al.  Double-blind, bilateral pain comparison with simultaneous injection of 2% lidocaine versus buffered 2% lidocaine for periocular anesthesia. , 2012, Ophthalmology.

[8]  S. Baek,et al.  Postoperative Pain Assessment for Upper Lid Blepharoplasty in Asians , 2012, Annals of plastic surgery.

[9]  A. Facskó,et al.  Is second eye phacoemulsification really more painful? , 2012, Wiener klinische Wochenschrift.

[10]  F. Ciucci,et al.  Pain during second eye cataract surgery under topical anesthesia: an intraindividual study , 2011, Graefe's Archive for Clinical and Experimental Ophthalmology.

[11]  R. Loeb,et al.  Pain perception in sequential cataract surgery: Comparison of first and second procedures , 2011, Journal of cataract and refractive surgery.

[12]  I. Wessels,et al.  Prospective Randomized Evaluation of Short-Term Complications When Using Buffered or Unbuffered Lidocaine 1% With Epinephrine for Blepharoplasty Surgery , 2010, Ophthalmic plastic and reconstructive surgery.

[13]  J. Ng,et al.  Comparison of Injection Pain of Articaine and Lidocaine in Eyelid Surgery , 2009, Ophthalmic plastic and reconstructive surgery.

[14]  I. Francis,et al.  Patient perceptions of second eye clear corneal cataract surgery using assisted topical anaesthesia , 2008, Eye.

[15]  J. Ameen,et al.  Postoperative pain assessment tools in day surgery: literature review. , 2004, Journal of advanced nursing.

[16]  J. Farrar,et al.  Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale , 2001, PAIN.

[17]  D. Overton,et al.  Pain on injection of prilocaine plain vs. lidocaine with epinephrine. A prospective double-blind study. , 2001, Journal of the American Dental Association.

[18]  O. Backhouse,et al.  Prilocaine versus lignocaine for minor lid procedures , 2000, Eye.

[19]  Peter Bjerring,et al.  Pain and mechanical injury of human skin following needle insertions , 1999, European journal of pain.

[20]  D. Schroeder,et al.  The effect of anesthetic patient education on preoperative patient anxiety. , 1999, Regional anesthesia and pain medicine.

[21]  K. Lundquist,et al.  Frostbite of the eyelids following inappropriate application of ice compresses. , 1996, Archives of ophthalmology.

[22]  K. I. Perman Upper eyelid blepharoplasty. , 1992, The Journal of dermatologic surgery and oncology.

[23]  A. Holland,et al.  Epidural anaesthesia with mixtures of bupivicaine and lidocaine. , 1984, Canadian Anaesthetists' Society journal.

[24]  L. Mather,et al.  Lidocaine and Bupivacaine Mixtures for Epidural Blockade , 1982, Anesthesiology.

[25]  A. Reading,et al.  The short term effects of psychological preparation for surgery. , 1979, Social science & medicine. Medical psychology & medical sociology.