Evaluation of guided imagery as treatment for recurrent abdominal pain in children: a randomized controlled trial

BackgroundBecause of the paucity of effective evidence-based therapies for children with recurrent abdominal pain, we evaluated the therapeutic effect of guided imagery, a well-studied self-regulation technique.Methods22 children, aged 5 – 18 years, were randomized to learn either breathing exercises alone or guided imagery with progressive muscle relaxation. Both groups had 4-weekly sessions with a therapist. Children reported the numbers of days with pain, the pain intensity, and missed activities due to abdominal pain using a daily pain diary collected at baseline and during the intervention. Monthly phone calls to the children reported the number of days with pain and the number of days of missed activities experienced during the month of and month following the intervention. Children with ≤ 4 days of pain/month and no missed activities due to pain were defined as being healed. Depression, anxiety, and somatization were measured in both children and parents at baseline.ResultsAt baseline the children who received guided imagery had more days of pain during the preceding month (23 vs. 14 days, P = 0.04). There were no differences in the intensity of painful episodes or any baseline psychological factors between the two groups. Children who learned guided imagery with progressive muscle relaxation had significantly greater decrease in the number of days with pain than those learning breathing exercises alone after one (67% vs. 21%, P = 0.05), and two (82% vs. 45%, P < 0.01) months and significantly greater decrease in days with missed activities at one (85% vs. 15%, P = 0.02) and two (95% vs. 77%. P = 0.05) months. During the two months of follow-up, more children who had learned guided imagery met the threshold of ≤ 4 day of pain each month and no missed activities (RR = 7.3, 95%CI [1.1,48.6]) than children who learned only the breathing exercises.ConclusionThe therapeutic efficacy of guided imagery with progressive muscle relaxation found in this study is consistent with our present understanding of the pathophysiology of recurrent abdominal pain in children. Although unfamiliar to many pediatricians, guided imagery is a simple, noninvasive therapy with potential benefit for treating children with RAP.

[1]  J. Rosh,et al.  Treatment of Functional Abdominal Pain in Childhood With Cognitive Behavioral Strategies , 2004, Journal of pediatric gastroenterology and nutrition.

[2]  P. Whorwell,et al.  Long term benefits of hypnotherapy for irritable bowel syndrome , 2003, Gut.

[3]  J. Dearlove,et al.  Dietary lactose and the child with abdominal pain. , 1983, British medical journal.

[4]  N. Talley,et al.  Initial validation of a bowel symptom questionnaire and measurement of chronic gastrointestinal symptoms in Australians. , 1995, Australian and New Zealand journal of medicine.

[5]  Melinda F. Davis,et al.  Systematic review of treatments for recurrent abdominal pain. , 2003, Pediatrics.

[6]  C. Macarthur,et al.  Pharmacological interventions for recurrent abdominal pain (RAP) in childhood. , 2002, The Cochrane database of systematic reviews.

[7]  J. Boyle Recurrent abdominal pain: an update. , 1997, Pediatrics in review.

[8]  A R Zinsmeister,et al.  esign of Treatment Trials for Functional Gastrointestinal isorders esign of Treatment Trials Committee : , 2006 .

[9]  P. McGrath,et al.  The epidemiology of pain in children and adolescents: a review , 1991, Pain.

[10]  J. Garber,et al.  Recurrent abdominal pain in children: psychiatric diagnoses and parental psychopathology. , 1990, Journal of the American Academy of Child and Adolescent Psychiatry.

[11]  I. Kutz,et al.  Meditation and psychotherapy: a rationale for the integration of dynamic psychotherapy, the relaxation response, and mindfulness meditation. , 1985, The American journal of psychiatry.

[12]  L. Derogatis,et al.  The SCL-90 and the MMPI: A Step in the Validation of a New Self-Report Scale , 1976, British Journal of Psychiatry.

[13]  D. Richards,et al.  The abdominal brain and enteric nervous system. , 1999, Journal of Alternative and Complementary Medicine.

[14]  C. Di Lorenzo,et al.  Adult outcomes of pediatric recurrent abdominal pain: do they just grow out of it? , 2001, Pediatrics.

[15]  C. Macarthur,et al.  Dietary interventions for recurrent abdominal pain (RAP) in childhood. , 2002, The Cochrane database of systematic reviews.

[16]  E. Lebenthal,et al.  Recurrent abdominal pain and lactose absorption in children. , 1981, Pediatrics.

[17]  Francis Creed,et al.  Psychosocial aspects of the functional gastrointestinal disorders. , 1999, Gastroenterology.

[18]  J. Hyams,et al.  Abdominal pain and irritable bowel syndrome in adolescents: a community-based study. , 1996, The Journal of pediatrics.

[19]  J. Øster RECURRENT ABDOMINAL PAIN, HEADACHE AND LIMB PAINS IN CHILDREN AND ADOLESCENTS , 1972, Pediatrics.

[20]  R. Anbar Self-Hypnosis for the Treatment of Functional Abdominal Pain in Childhood , 2001, Clinical pediatrics.

[21]  J. Hyams,et al.  Recurrent abdominal pain and the biopsychosocial model of medical practice. , 1998, The Journal of pediatrics.

[22]  M S Smith,et al.  Stress Management Techniques in Childhood and Adolescence , 1987, Clinical pediatrics.

[23]  B. Birmaher,et al.  Recurrent abdominal pain, anxiety, and depression in primary care. , 2004, Pediatrics.

[24]  M. Kovács Rating scales to assess depression in school-aged children. , 1981, Acta paedopsychiatrica.

[25]  S. Cucchiara,et al.  [Recurrent abdominal pain]. , 2007, Minerva pediatrica.

[26]  P. McGrath,et al.  The use of dietary fiber in the management of simple, childhood, idiopathic, recurrent, abdominal pain. Results in a prospective, double-blind, randomized, controlled trial. , 1985, American journal of diseases of children.

[27]  S. Weisman,et al.  Complementary therapies for acute pediatric pain management. , 2000, Pediatric clinics of North America.

[28]  C. Stanger,et al.  Attentional biases to pain and social threat in children with recurrent abdominal pain. , 2006, Journal of pediatric psychology.

[29]  C. Schechter,et al.  Double-Blind, Placebo-Controlled Trial of Famotidine in Children with Abdominal Pain and Dyspepsia , 2001, Digestive Diseases and Sciences.

[30]  K. Olden,et al.  Psychosocial aspects of functional gastrointestinal disorders. , 2003, Gastroenterology clinics of North America.

[31]  R. Gevirtz,et al.  Treatment of recurrent abdominal pain: components analysis of four treatment protocols. , 2000, Journal of pediatric gastroenterology and nutrition.

[32]  J. Garber,et al.  Somatization symptoms in a community sample of children and adolescents: Further validation of the Children's Somatization Inventory. , 1991 .

[33]  A. Buss,et al.  Temperament: Early Developing Personality Traits , 1984 .

[34]  J. Oster Recurrent abdominal pain, headache and limb pains in children and adolescents. , 1972, Pediatrics.

[35]  T. Ball,et al.  A Pilot Study of the Use of Guided Imagery for the Treatment of Recurrent Abdominal Pain in Children , 2003, Clinical pediatrics.

[36]  J APLEY,et al.  Recurrent Abdominal Pains: A Field Survey of 1,000 School Children , 1958, Archives of disease in childhood.

[37]  J. Croffie,et al.  Recurrent Abdominal Pain in Children-A Retrospective Study of Outcome in a Group Referred to a Pediatric Gastroenterology Practice , 2000, Clinical pediatrics.

[38]  D. Janicke,et al.  Empirically supported treatments in pediatric psychology: recurrent abdominal pain. , 1999, Journal of pediatric psychology.

[39]  Rachel M. Fleissner,et al.  Irritable bowel syndrome and recurrent abdominal pain. A comparative review. , 1999, Psychosomatics.

[40]  E. Blanchard,et al.  Relaxation training as a treatment for irritable bowel syndrome , 1993, Biofeedback and self-regulation.

[41]  J. Beasley Psychiatric consultation in somatization disorder. , 1986, The New England journal of medicine.

[42]  M. F. Christensen Recurrent abdominal pain and dietary fiber. , 1986, American journal of diseases of children.

[43]  M. Sanders,et al.  The treatment of recurrent abdominal pain in children: a controlled comparison of cognitive-behavioral family intervention and standard pediatric care. , 1994, Journal of consulting and clinical psychology.

[44]  G. Russell,et al.  Prevalence and clinical features of abdominal migraine compared with those of migraine headache. , 1995, Archives of disease in childhood.

[45]  Li Bu Recurrent abdominal pain in childhood: an approach to common disorders. , 1987 .

[46]  L. Mullins,et al.  Survey of pediatricians' management practices for recurrent abdominal pain. , 1994, Journal of pediatric psychology.

[47]  D. Moher,et al.  The Revised CONSORT Statement for Reporting Randomized Trials: Explanation and Elaboration , 2001, Annals of Internal Medicine.

[48]  G. Parker,et al.  The parental bonding instrument , 1979, Social Psychiatry and Psychiatric Epidemiology.

[49]  S. Zeger,et al.  Longitudinal data analysis using generalized linear models , 1986 .

[50]  J. Parker,et al.  The Multidimensional Anxiety Scale for Children (MASC): factor structure, reliability, and validity. , 1997, Journal of the American Academy of Child and Adolescent Psychiatry.

[51]  R. Reeve,et al.  The faces pain scale for the self-assessment of the severity of pain experienced by children: Development, initial validation, and preliminary investigation for ratio scale properties , 1990, Pain.

[52]  G. Russell,et al.  Double blind placebo controlled trial of pizotifen syrup in the treatment of abdominal migraine. , 1995, Archives of disease in childhood.

[53]  G. Banez,et al.  Treatment of Recurrent Abdominal Pain: Components Analysis of Four Treatment Protocols , 2001, Clinical pediatrics.

[54]  M. Dadds,et al.  Cognitive-behavioral treatment of recurrent nonspecific abdominal pain in children: an analysis of generalization, maintenance, and side effects. , 1989, Journal of consulting and clinical psychology.

[55]  P. Andrews,et al.  Fundamentals of neurogastroenterology , 1999, Gut.

[56]  B. Zuckerman,et al.  Stomachaches and headaches in a community sample of preschool children. , 1986, Pediatrics.

[57]  R. Monson,et al.  Psychiatric consultation in somatization disorder. A randomized controlled study. , 1986, The New England journal of medicine.

[58]  T. Ball,et al.  Methodological challenges to treatment trials for recurrent abdominal pain in children. , 2003, Archives of pediatrics & adolescent medicine.