Raf-1 Kinase Is Required for Cardiac Hypertrophy and Cardiomyocyte Survival in Response to Pressure Overload
暂无分享,去创建一个
[1] P. Clarke,et al. Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK , 2003, Nature Cell Biology.
[2] Timothy E Hewett,et al. Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling. , 2003, The Journal of clinical investigation.
[3] Attila Kovacs,et al. The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis. , 2003, The Journal of clinical investigation.
[4] C. Proud,et al. Regulation of the phosphorylation of elongation factor 2 by MEK‐dependent signalling in adult rat cardiomyocytes , 2002, FEBS letters.
[5] C. Proud,et al. Ras/Erk Signaling Is Essential for Activation of Protein Synthesis by Gq Protein-Coupled Receptor Agonists in Adult Cardiomyocytes , 2002, Circulation research.
[6] Sang-Gu Hwang,et al. p38 Kinase Regulates Nitric Oxide-induced Apoptosis of Articular Chondrocytes by Accumulating p53 via NFκB-dependent Transcription and Stabilization by Serine 15 Phosphorylation* , 2002, The Journal of Biological Chemistry.
[7] Manuel Mayr,et al. Mechanical Stress‐induced DNA damage and rac‐p38MAPK Signal Pathways Mediate p53‐dependent Apoptosis in Vascular Smooth Muscle Cells , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[8] L. Luttrell. Activation and targeting of mitogen-activated protein kinases by G-protein-coupled receptors. , 2002, Canadian journal of physiology and pharmacology.
[9] S. Kudoh,et al. Integrins Play a Critical Role in Mechanical Stress–Induced p38 MAPK Activation , 2002, Hypertension.
[10] K. Chien,et al. Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Gαq/Gα11 in cardiomyocytes , 2001, Nature Medicine.
[11] P. Okin,et al. Prognostic implications of left ventricular hypertrophy. , 2001, American heart journal.
[12] M. Hennersdorf,et al. Arterial hypertension and cardiac arrhythmias , 2001, Journal of hypertension.
[13] G. Dorn,et al. RGS4 reduces contractile dysfunction and hypertrophic gene induction in Galpha q overexpressing mice. , 2001, Journal of molecular and cellular cardiology.
[14] R. Kitsis,et al. The MEK1–ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice , 2000, The EMBO journal.
[15] C. Pham,et al. Striated muscle-specific beta(1D)-integrin and FAK are involved in cardiac myocyte hypertrophic response pathway. , 2000, American journal of physiology. Heart and circulatory physiology.
[16] John C. Lee,et al. Extracellular Signal-regulated Kinase Plays an Essential Role in Hypertrophic Agonists, Endothelin-1 and Phenylephrine-induced Cardiomyocyte Hypertrophy* , 2000, The Journal of Biological Chemistry.
[17] J. Taylor,et al. A Role for Focal Adhesion Kinase in Phenylephrine-induced Hypertrophy of Rat Ventricular Cardiomyocytes* , 2000, The Journal of Biological Chemistry.
[18] Anthony J. Muslin,et al. 14‐3‐3 proteins block apoptosis and differentially regulate MAPK cascades , 2000, The EMBO journal.
[19] Anthony J. Muslin,et al. RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload. , 1999, The Journal of clinical investigation.
[20] C. Roberts,et al. Extracellular Signal-regulated Protein Kinase Activation Is Required for the Anti-hypertrophic Effect of Atrial Natriuretic Factor in Neonatal Rat Ventricular Myocytes* , 1999, The Journal of Biological Chemistry.
[21] K Kornfeld,et al. Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase. , 1999, Genes & development.
[22] A. Thorburn,et al. Ras and rho are required for galphaq-induced hypertrophic gene expression in neonatal rat cardiac myocytes. , 1998, Journal of molecular and cellular cardiology.
[23] A. Clerk,et al. Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptors. , 1997, Cellular signalling.
[24] D. Morrison,et al. The complexity of Raf-1 regulation. , 1997, Current opinion in cell biology.
[25] George Cooper,et al. Association of Tyrosine-phosphorylated c-Src with the Cytoskeleton of Hypertrophying Myocardium* , 1997, The Journal of Biological Chemistry.
[26] J. Balligand,et al. Regulation of bFGF expression and ANG II secretion in cardiac myocytes and microvascular endothelial cells. , 1997, The American journal of physiology.
[27] J. Brugge,et al. Integrins and signal transduction pathways: the road taken. , 1995, Science.
[28] T. Hunter,et al. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase , 1994, Nature.
[29] A. Thorburn,et al. Raf-1 kinase activity is necessary and sufficient for gene expression changes but not sufficient for cellular morphology changes associated with cardiac myocyte hypertrophy. , 1994, The Journal of biological chemistry.
[30] K. Guan,et al. The mitogen activated protein kinase signal transduction pathway: from the cell surface to the nucleus. , 1994, Cellular signalling.
[31] T. Roberts,et al. Signal transduction pathways involving the raf proto-oncogene , 1994, Cancer and Metastasis Reviews.
[32] A. Wolfman,et al. The 3Rs of life: Ras, Raf and growth regulation. , 1994, Trends in genetics : TIG.
[33] J Downward,et al. The GRB2/Sem‐5 adaptor protein , 1994, FEBS letters.
[34] J. Sadoshima,et al. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro , 1993, Cell.
[35] Anthony J. Muslin,et al. Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos , 1993, Molecular and cellular biology.
[36] Anthony J. Muslin,et al. Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF , 1993, Cell.
[37] Z. Werb,et al. Signal transduction by integrin receptors for extracellular matrix: Cooperative processing of extracellular information , 1992, Current Biology.
[38] Richard O. Hynes,et al. Integrins: Versatility, modulation, and signaling in cell adhesion , 1992, Cell.
[39] J. Robbins,et al. Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice. , 1991, The Journal of biological chemistry.
[40] X. F. Zhang,et al. Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade. , 2001, Recent progress in hormone research.
[41] K. Chien,et al. Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Galphaq/Galpha11 in cardiomyocytes. , 2001, Nature medicine.
[42] J. Sadoshima,et al. The cellular and molecular response of cardiac myocytes to mechanical stress. , 1997, Annual review of physiology.