The REGγ proteasome regulates hepatic lipid metabolism through inhibition of autophagy.
暂无分享,去创建一个
D. Edwards | B. O’Malley | Q. Mo | Chuangui Wang | Haibin Wei | Jian Liu | Xiaotao Li | Lei Li | Q. Zhai | Chen Hu | L. Chan | Qiao Li | Shengping Zhang | Guangjian Fan | Shixia Huang | Y. E. Chin | Peipei Shan | Wenzhen Xiao | Bert W. O’Malley | Lianhui Sun | Jinqin Liu | Shuxian Dong | Caifeng Jia | Yubing Li | Yipin Zheng | Wen Zhang | Fuli Jia | Qianxing Mo
[1] S. Jung,et al. Site-specific Acetylation of the Proteasome Activator REGγ Directs Its Heptameric Structure and Functions* , 2013, The Journal of Biological Chemistry.
[2] S. Kaneko,et al. Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver , 2013, Diabetes.
[3] D. Accili,et al. Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ , 2012, Cell.
[4] N. Danial,et al. Polysome Profiling in Liver Identifies Dynamic Regulation of Endoplasmic Reticulum Translatome by Obesity and Fasting , 2012, PLoS genetics.
[5] B. Bay,et al. Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy. , 2012, The Journal of clinical investigation.
[6] Qinxi Li,et al. GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy , 2012, Science.
[7] Li Yu,et al. Function and Molecular Mechanism of Acetylation in Autophagy Regulation , 2012, Science.
[8] Yongping Cui,et al. Roles of Kruppel-associated Box (KRAB)-associated Co-repressor KAP1 Ser-473 Phosphorylation in DNA Damage Response* , 2012, The Journal of Biological Chemistry.
[9] A. Cuervo,et al. Lipophagy: Connecting Autophagy and Lipid Metabolism , 2012, International journal of cell biology.
[10] Jingxia Wu,et al. Liver Patt1 deficiency protects male mice from age-associated but not high-fat diet-induced hepatic steatosis[S] , 2012, Journal of Lipid Research.
[11] Jianping Ye,et al. Sirtuin 1 (SIRT1) Protein Degradation in Response to Persistent c-Jun N-terminal Kinase 1 (JNK1) Activation Contributes to Hepatic Steatosis in Obesity* , 2011, The Journal of Biological Chemistry.
[12] R. de Cabo,et al. Negative Regulation of STAT3 Protein-mediated Cellular Respiration by SIRT1 Protein* , 2011, The Journal of Biological Chemistry.
[13] Lee H. Dicker,et al. Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity , 2011, Nature.
[14] Shanlou Qiao,et al. REGγ modulates p53 activity by regulating its cellular localization , 2010, Journal of Cell Science.
[15] Guido Kroemer,et al. Autophagy and the integrated stress response. , 2010, Molecular cell.
[16] Ping Li,et al. Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. , 2010, Cell metabolism.
[17] M. Czaja. Autophagy in health and disease. 2. Regulation of lipid metabolism and storage by autophagy: pathophysiological implications. , 2010, American journal of physiology. Cell physiology.
[18] R. de Cabo,et al. JNK1 Phosphorylates SIRT1 and Promotes Its Enzymatic Activity , 2009, PloS one.
[19] M. Komatsu,et al. Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis , 2009, Proceedings of the National Academy of Sciences.
[20] M. Czaja,et al. Autophagy regulates lipid metabolism , 2009, Nature.
[21] Qing Xu,et al. Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. , 2009, Cell metabolism.
[22] In Hye Lee,et al. Regulation of Autophagy by the p300 Acetyltransferase* , 2009, Journal of Biological Chemistry.
[23] D. Rubinsztein,et al. Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates , 2009, Molecular cell.
[24] P. Pfluger,et al. Sirt1 protects against high-fat diet-induced metabolic damage , 2008, Proceedings of the National Academy of Sciences.
[25] Nicholas E. Bruns,et al. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy , 2008, Proceedings of the National Academy of Sciences.
[26] J. Qin,et al. Negative regulation of the deacetylase SIRT1 by DBC1 , 2008, Nature.
[27] N. Mizushima,et al. Autophagy: process and function. , 2007, Genes & development.
[28] J. Yao,et al. Effect of starvation on global gene expression and proteolysis in rainbow trout (Oncorhynchus mykiss) , 2007, BMC Genomics.
[29] D. Stolz,et al. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. , 2007, The American journal of pathology.
[30] B. O’Malley,et al. Ubiquitin- and ATP-independent proteolytic turnover of p21 by the REGgamma-proteasome pathway. , 2007, Molecular cell.
[31] D. Stolz,et al. Differential Effects of Endoplasmic Reticulum Stress-induced Autophagy on Cell Survival* , 2007, Journal of Biological Chemistry.
[32] W. Gu,et al. Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage , 2006, Nature Cell Biology.
[33] A. Malovannaya,et al. The SRC-3/AIB1 Coactivator Is Degraded in a Ubiquitin- and ATP-Independent Manner by the REGγ Proteasome , 2006, Cell.
[34] S. Baylin,et al. Tumor Suppressor HIC1 Directly Regulates SIRT1 to Modulate p53-Dependent DNA-Damage Responses , 2005, Cell.
[35] S. Nemoto,et al. Nutrient Availability Regulates SIRT1 Through a Forkhead-Dependent Pathway , 2004, Science.
[36] R. Gottlieb. Autophagy in Health and Disease , 2004, Science.
[37] L. Guarente,et al. corrigendum: Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ , 2004, Nature.
[38] Namjin Chung,et al. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ , 2004, Nature.
[39] Steven P. Gygi,et al. Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase , 2004, Science.
[40] Lance F. Barton,et al. Immune Defects in 28-kDa Proteasome Activator γ-Deficient Mice1 , 2004, The Journal of Immunology.
[41] Delin Chen,et al. Negative Control of p53 by Sir2α Promotes Cell Survival under Stress , 2001, Cell.
[42] L. Guarente,et al. Sir2 links chromatin silencing, metabolism, and aging. , 2000, Genes & development.
[43] M. Kasahara,et al. Growth Retardation in Mice Lacking the Proteasome Activator PA28γ* , 1999, The Journal of Biological Chemistry.
[44] C. Wójcik. Proteasome activator subunit PA28α and related Ki antigen (PA28γ) are absent from the nuclear fraction purified by sucrose gradient centrifugation , 1999 .
[45] K. Ferrell,et al. Purification of an 11 S regulator of the multicatalytic protease. , 1992, The Journal of biological chemistry.
[46] C. Slaughter,et al. Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain). , 1992, The Journal of biological chemistry.
[47] Lance F. Barton,et al. Immune defects in 28-kDa proteasome activator gamma-deficient mice. , 2004, Journal of immunology.
[48] L. Guarente,et al. Negative control of p53 by Sir2alpha promotes cell survival under stress. , 2001, Cell.
[49] C. Wójcik. Proteasome activator subunit PA28 alpha and related Ki antigen (PA28 gamma) are absent from the nuclear fraction purified by sucrose gradient centrifugation. , 1999, International Journal of Biochemistry and Cell Biology.