Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch
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C. Hess | S. Dimeloe | M. Fischer | P. Gubser | Leyla Razik | G. Bantug | A. Jauch | Gideon Hoenger | Bojana Durovic
[1] B. Faubert,et al. Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis , 2013, Cell.
[2] M. Sykes,et al. Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets. , 2013, Immunity.
[3] David K. Finlay,et al. PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells , 2012, The Journal of experimental medicine.
[4] Chao Lu,et al. Metabolic regulation of epigenetics. , 2012, Cell metabolism.
[5] M. Sirover,et al. Subcellular dynamics of multifunctional protein regulation: Mechanisms of GAPDH intracellular translocation , 2012, Journal of cellular biochemistry.
[6] L. Picker,et al. Hidden Memories: Frontline Memory T Cells and Early Pathogen Interception , 2012, The Journal of Immunology.
[7] M. Hall,et al. Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c. , 2012, Cell metabolism.
[8] N. Weng,et al. The molecular basis of the memory T cell response: differential gene expression and its epigenetic regulation , 2012, Nature Reviews Immunology.
[9] G. V. D. van der Windt,et al. Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development. , 2012, Immunity.
[10] M. McBurney,et al. Sirtuin 1 in immune regulation and autoimmunity , 2012, Immunology and cell biology.
[11] D. Green,et al. The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. , 2011, Immunity.
[12] M. V. Vander Heiden,et al. Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. , 2011, Annual review of cell and developmental biology.
[13] D. Green,et al. HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells , 2011, The Journal of experimental medicine.
[14] S. Mazurek. Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells. , 2011, The international journal of biochemistry & cell biology.
[15] P. Houghton,et al. Preclinical Characterization of OSI-027, a Potent and Selective Inhibitor of mTORC1 and mTORC2: Distinct from Rapamycin , 2011, Molecular Cancer Therapeutics.
[16] S. Berger,et al. Cutting Edge: Persistently Open Chromatin at Effector Gene Loci in Resting Memory CD8+ T Cells Independent of Transcriptional Status , 2011, The Journal of Immunology.
[17] Dianqing Wu,et al. Evidence for Direct Activation of mTORC2 Kinase Activity by Phosphatidylinositol 3,4,5-Trisphosphate* , 2011, The Journal of Biological Chemistry.
[18] J. Christensen,et al. The Role of CD80/CD86 in Generation and Maintenance of Functional Virus-Specific CD8+ T Cells in Mice Infected with Lymphocytic Choriomeningitis Virus , 2010, The Journal of Immunology.
[19] T. Gaber,et al. Effects of hypoxia and/or lack of glucose on cellular energy metabolism and cytokine production in stimulated human CD4+ T lymphocytes. , 2010, Immunology letters.
[20] P. Doherty,et al. Interplay between chromatin remodeling and epigenetic changes during lineage-specific commitment to granzyme B expression , 2010, The Journal of Immunology.
[21] S. Jameson,et al. Diversity in T cell memory: an embarrassment of riches. , 2009, Immunity.
[22] Justin R. Cross,et al. ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation , 2009, Science.
[23] S. Sieg,et al. Faculty Opinions recommendation of Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge. , 2009 .
[24] G. Pantaleo,et al. Distinct Profiles of Cytotoxic Granules in Memory CD8 T Cells Correlate with Function, Differentiation Stage, and Antigen Exposure , 2009, Journal of Virology.
[25] J. Rathmell,et al. Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival , 2008, Journal of leukocyte biology.
[26] K. Sakamoto,et al. Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic. , 2008, American journal of physiology. Endocrinology and metabolism.
[27] J. Rathmell,et al. Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways1 , 2008, The Journal of Immunology.
[28] E. Wherry,et al. Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection. , 2007, Immunity.
[29] D. Guertin,et al. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. , 2006, Developmental cell.
[30] W. Wood,et al. Histone acetylation is associated with differential gene expression in the rapid and robust memory CD8(+) T-cell response. , 2006, Blood.
[31] J. Harty,et al. Inflaming the CD8+ T cell response. , 2006, Immunity.
[32] Craig B. Thompson,et al. Fuel feeds function: energy metabolism and the T-cell response , 2005, Nature Reviews Immunology.
[33] T. Gajewski,et al. Glucose Availability Regulates IFN-γ Production and p70S6 Kinase Activation in CD8+ Effector T Cells1 , 2005, The Journal of Immunology.
[34] G. Tsujimoto,et al. Upregulation of the transcript level of GTPase activating protein KIAA0603 in T cells from patients with atopic dermatitis , 2004, FEBS letters.
[35] L. Lefrançois,et al. Dynamics of blood-borne CD8 memory T cell migration in vivo. , 2004, Immunity.
[36] S. Mohr,et al. Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: a role in high glucose-induced apoptosis in retinal Müller cells. , 2004 .
[37] K. Frauwirth,et al. Regulation of T Lymphocyte Metabolism , 2004, The Journal of Immunology.
[38] J. Mazzola,et al. Subcellular localization of human glyceraldehyde-3-phosphate dehydrogenase is independent of its glycolytic function. , 2003, Biochimica et biophysica acta.
[39] F. Sallusto,et al. Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines. , 2003, Blood.
[40] C. Thompson,et al. The CD28 signaling pathway regulates glucose metabolism. , 2002, Immunity.
[41] C. Thompson,et al. Homeostatic control of lymphocyte survival: potential origins and implications , 2002, Nature Immunology.
[42] L. Lefrançois,et al. Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue , 2001, Science.
[43] B. Boehm,et al. Direct Visualization of Cytokine-Producing Recall Antigen-Specific CD4 Memory T Cells in Healthy Individuals and HIV Patients1 , 2000, The Journal of Immunology.
[44] R. Abraham,et al. Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3‐kinase inhibitors, wortmannin and LY294002. , 1996, The EMBO journal.
[45] M. Guppy,et al. Glucose is essential for proliferation and the glycolytic enzyme induction that provokes a transition to glycolytic energy production. , 1994, The Journal of biological chemistry.
[46] E. Newsholme,et al. Maximum activities of key enzymes of glycolysis, glutaminolysis, pentose phosphate pathway and tricarboxylic acid cycle in normal, neoplastic and suppressed cells. , 1990, The Biochemical journal.
[47] R. Pitkin. An embarrassment of riches. , 1989, Obstetrics and gynecology.
[48] Min Wu,et al. Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells. , 2007, American journal of physiology. Cell physiology.
[49] S. Jennings,et al. Memory CD8 T Cells Require CD28 Costimulation , 2007 .