Trans‐synaptic axonal degeneration in the visual pathway in multiple sclerosis

To evaluate the association between the damage to the anterior and posterior visual pathway as evidence of the presence of retrograde and anterograde trans‐synaptic degeneration in multiple sclerosis (MS).

[1]  S. Reingold,et al.  Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria” , 2005, Annals of neurology.

[2]  Alan Cowey,et al.  Transneuronal retrograde degeneration of retinal ganglion cells and optic tract in hemianopic monkeys and humans. , 2011, Brain : a journal of neurology.

[3]  Alan Cowey,et al.  Transneuronal retrograde degeneration of retinal ganglion cells following restricted lesions of striate cortex in the monkey , 2000, Experimental Brain Research.

[4]  A M Dale,et al.  Measuring the thickness of the human cerebral cortex from magnetic resonance images. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[5]  David H. Miller,et al.  Imaging outcomes for neuroprotection and repair in multiple sclerosis trials , 2009, Nature Reviews Neurology.

[6]  B. Falsini,et al.  Retinal ganglion cell dysfunction in humans following post-geniculate lesions: specific spatio–temporal losses revealed by pattern ERG , 1999, Vision Research.

[7]  G. Plant,et al.  Retrograde trans-synaptic retinal ganglion cell loss identified by optical coherence tomography. , 2009, Brain : a journal of neurology.

[8]  P M Matthews,et al.  Size-selective neuronal changes in the anterior optic pathways suggest a differential susceptibility to injury in multiple sclerosis. , 2001, Brain : a journal of neurology.

[9]  C. Polman,et al.  Clinico-pathological evidence that axonal loss underlies disability in progressive multiple sclerosis , 2010, Multiple sclerosis.

[10]  Heidi Johansen-Berg,et al.  A combined post-mortem magnetic resonance imaging and quantitative histological study of multiple sclerosis pathology , 2012, Brain : a journal of neurology.

[11]  H. Bridge,et al.  Imaging reveals optic tract degeneration in hemianopia. , 2011, Investigative ophthalmology & visual science.

[12]  M. Filippi,et al.  Mapping regional grey and white matter atrophy in relapsing–remitting multiple sclerosis , 2012, Multiple sclerosis.

[13]  Shiv Saidha,et al.  Relationships between retinal axonal and neuronal measures and global central nervous system pathology in multiple sclerosis. , 2012, JAMA neurology.

[14]  Joaquín Goñi,et al.  Contribution of white matter lesions to gray matter atrophy in multiple sclerosis: evidence from voxel-based analysis of T1 lesions in the visual pathway. , 2009, Archives of neurology.

[15]  Ludwig Kappos,et al.  Longitudinal gray matter changes in multiple sclerosis—Differential scanner and overall disease‐related effects , 2012, Human brain mapping.

[16]  F. Goldby A NOTE ON TRANSNEURONAL ATROPHY IN THE HUMAN LATERAL GENICULATE BODY , 1957, Journal of neurology, neurosurgery, and psychiatry.

[17]  David H. Miller,et al.  Selective magnetization transfer ratio decrease in the visual cortex following optic neuritis. , 2006, Brain : a journal of neurology.

[18]  B. A. Sabel,et al.  Quantification of the Human Lateral Geniculate Nucleus In Vivo Using MR Imaging Based on Morphometry: Volume Loss with Age , 2012, American Journal of Neuroradiology.

[19]  C. Poser,et al.  Diagnostic criteria for multiple sclerosis , 2001, Clinical Neurology and Neurosurgery.

[20]  R. Beck,et al.  Design, methods, and conduct of the Optic Neuritis Treatment Trial. , 1993, Controlled clinical trials.

[21]  C. Pfueller,et al.  Metabolic Changes in the Visual Cortex Are Linked to Retinal Nerve Fiber Layer Thinning in Multiple Sclerosis , 2011, PloS one.

[22]  Neeru Gupta,et al.  Glaucoma of the brain: a disease model for the study of transsynaptic neural degeneration. , 2008, Progress in brain research.

[23]  David H. Miller,et al.  Modeling axonal degeneration within the anterior visual system: implications for demonstrating neuroprotection in multiple sclerosis. , 2008, Archives of neurology.

[24]  Axel Petzold,et al.  The OSCAR-IB Consensus Criteria for Retinal OCT Quality Assessment , 2012, PloS one.

[25]  Simon B. Eickhoff,et al.  A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data , 2005, NeuroImage.

[26]  Eliza M. Gordon-Lipkin,et al.  Damage to the optic radiation in multiple sclerosis is associated with retinal injury and visual disability. , 2009, Archives of neurology.

[27]  S. Graham,et al.  Transsynaptic retinal degeneration in optic neuropathies: optical coherence tomography study. , 2012, Investigative ophthalmology & visual science.

[28]  J. VanBuren TRANS-SYNAPTIC RETROGRADE DEGENERATION IN THE VISUAL SYSTEM OF PRIMATES. , 1963, Journal of neurology, neurosurgery, and psychiatry.

[29]  Caron Chapman,et al.  Diffusion tensor imaging of the optic radiations after optic neuritis , 2012, Human brain mapping.

[30]  K. Shindler,et al.  Inflammatory demyelination induces axonal injury and retinal ganglion cell apoptosis in experimental optic neuritis. , 2008, Experimental eye research.

[31]  J. M. Buren Trans-synaptic retrograde degeneration in the visual system of primates , 1963, Journal of neurology, neurosurgery, and psychiatry.

[32]  G. Plant,et al.  The time course of retrograde trans-synaptic degeneration following occipital lobe damage in humans. , 2012, Brain : a journal of neurology.

[33]  R. Franklin,et al.  Neuroprotection and repair in multiple sclerosis , 2012, Nature Reviews Neurology.

[34]  P. Villoslada,et al.  Color vision is strongly associated with retinal thinning in multiple sclerosis , 2012, Multiple sclerosis.

[35]  J. Vonsattel,et al.  Direct demonstration of transsynaptic degeneration in the human visual system: a comparison of retrograde and anterograde changes , 1982, Journal of neurology, neurosurgery, and psychiatry.

[36]  Geoff J M Parker,et al.  Optic radiation changes after optic neuritis detected by tractography‐based group mapping , 2005, Human brain mapping.

[37]  Alexander Klistorner,et al.  Axonal loss and myelin in early ON loss in postacute optic neuritis , 2008, Annals of neurology.

[38]  Pablo Villoslada,et al.  Mapping the brain pathways of declarative verbal memory: Evidence from white matter lesions in the living human brain , 2008, NeuroImage.

[39]  S. Takashima,et al.  Olivocerebellar retrograde trans-synaptic degeneration from the lateral cerebellar hemisphere to the medial inferior olivary nucleus in an infant , 1994, Brain and Development.

[40]  P. Calabresi,et al.  Optical Coherence Tomography (OCT): Imaging the Visual Pathway as a Model for Neurodegeneration , 2010, Neurotherapeutics.