Effectiveness of Pre-administered Natural Sweet-tasting Solution for Decreasing Pain Associated with Dental Injections in Children: A Split-mouth Randomized Controlled Trial.

AIM This study aimed to discern if a prior intake of a natural sweet remedy (honey) impacted pain perception during intraoral injections. MATERIALS AND METHODS One hundred healthy children who needed the same treatment bilaterally in either arch which required local anesthetic administration (infiltration in maxillary arch and inferior alveolar nerve block in mandibular arch) were recruited. The patients' demographic details were recorded. Local anesthesia was administered after taking 5 mL of honey solution on the test side and 5 mL of sterile water on the control side. Subjective pain perception during injection was measured using Wong-Baker Faces Pain Rating Scale and objective pain by sound, eye, body movement (SEM) rating scale. The parametric data were analyzed using a paired Student's t-test (p <0.05). Level of consensus between the two scales was assessed using Pearson's correlation. RESULTS The test side yielded lower mean Wong-Baker Faces Pain Rating Scale (3.72 ± 1.80) and SEM (4.12 ± 1.04) scores than the control side (6.00 ± 2.06 and 5.00 ± 1.45 respectively). This was statistically significant. CONCLUSION The administering of a natural sweet solution such as honey before dental injections in children tends to reduce the discomfort and pain associated with the procedure. CLINICAL SIGNIFICANCE Pain management is of utmost importance in dentistry, especially among children. The consumption of natural foods such as honey helps in decreasing injection pain perception, making the child cooperative, and thereby allowing the dentist to provide the best dental care.

[1]  M. Bortoluzzi,et al.  Evaluation of pain, disruptive behaviour and anxiety in children aging 5-8 years old undergoing different modalities of local anaesthetic injection for dental treatment: a randomised clinical trial , 2020, Acta odontologica Scandinavica.

[2]  F. Soares,et al.  Factors Associated with Dental Fear and Anxiety in Children Aged 7 to 9 Years , 2019, Dentistry journal.

[3]  Jennifer Tung,et al.  Clinical Performance of the DentalVibe® Injection System on Pain Perception During Local Anesthesia in Children. , 2018, Journal of dentistry for children.

[4]  F. Ghaderi,et al.  Pain management during needle insertion with low level laser. , 2016, European journal of paediatric dentistry.

[5]  Z. Khamverdi,et al.  Antibacterial Activity of Honey on Cariogenic Bacteria , 2013, Journal of dentistry.

[6]  Douglas S. Diekema,et al.  Improving childhood vaccination rates. , 2012, The New England journal of medicine.

[7]  J. Mennella,et al.  Innate and learned preferences for sweet taste during childhood , 2011, Current opinion in clinical nutrition and metabolic care.

[8]  J. Beyene,et al.  Efficacy of sweet solutions for analgesia in infants between 1 and 12 months of age: a systematic review , 2010, Archives of Disease in Childhood.

[9]  F. Moriya,et al.  Sweet taste-induced analgesia: an fMRI study , 2010, Neuroreport.

[10]  P. Donnan,et al.  The prevalence of dental anxiety in a group of 13- and 14-year-old Scottish children. , 2009, International journal of paediatric dentistry.

[11]  J. Mennella,et al.  Sucrose-induced analgesia is related to sweet preferences in children but not adults , 2005, Pain.

[12]  I. Younis,et al.  Taking the 'ouch' out - effect of buffering commercial xylocaine on infiltration and procedure pain - a prospective, randomised, double-blind, controlled trial. , 2004, Annals of the Royal College of Surgeons of England.

[13]  S. Young,et al.  Effects of chewing gum on responses to routine painful procedures in children , 2003, Physiology & Behavior.

[14]  C. Greenberg,et al.  Pain assessment in infants and children. , 2000, Pediatric clinics of North America.

[15]  P Milgrom,et al.  Four dimensions of fear of dental injections. , 1997, Journal of the American Dental Association.

[16]  S. Young,et al.  The cold pressor test in children: Methodological aspects and the analgesic effect of intraoral sucrose , 1994, Pain.

[17]  J. Dean,et al.  Local Anesthesia and Pain Control for the Child and Adolescent , 2016 .

[18]  J. Beyene,et al.  Sweet tasting solutions for reduction of needle-related procedural pain in children aged one to 16 years. , 2011, The Cochrane database of systematic reviews.

[19]  G. Koren,et al.  A Critical Review of the Topical Local Anesthetic Amethocaine (Ametop™) for Pediatric Pain , 2005, Paediatric drugs.

[20]  B. Stevens,et al.  Sucrose for analgesia in newborn infants undergoing painful procedures. , 2001, The Cochrane database of systematic reviews.

[21]  J Camp,et al.  The golden age of quackery. , 1978, British history illustrated.