IκB kinase-α acts in the epidermis to control skeletal and craniofacial morphogenesis

[1]  R. Gaynor,et al.  Histone H3 phosphorylation by IKK-α is critical for cytokine-induced gene expression , 2003, Nature.

[2]  J. C. Belmonte,et al.  MKP3 mediates the cellular response to FGF8 signalling in the vertebrate limb , 2003, Nature Cell Biology.

[3]  M. Karin,et al.  The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion , 2003, Nature Medicine.

[4]  Rolf Zeller,et al.  Progression of Vertebrate Limb Development Through SHH-Mediated Counteraction of GLI3 , 2002, Science.

[5]  E. Schmidt,et al.  IKKα Provides an Essential Link between RANK Signaling and Cyclin D1 Expression during Mammary Gland Development , 2001, Cell.

[6]  W. Birchmeier,et al.  Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices. , 2001, Development.

[7]  Michael Karin,et al.  Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway , 2001, Science.

[8]  M. Karin,et al.  IKKα controls formation of the epidermis independently of NF-κB , 2001, Nature.

[9]  C. Tabin,et al.  Constructive antagonism in limb development. , 2000, Current opinion in genetics & development.

[10]  K. Lyons,et al.  The type I BMP receptor BMPRIB is required for chondrogenesis in the mouse limb. , 2000, Development.

[11]  N. Hacohen,et al.  Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. , 1999, Development.

[12]  Andrew P. McMahon,et al.  Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds , 1999, Nature.

[13]  I. Verma,et al.  IKK1-deficient mice exhibit abnormal development of skin and skeleton. , 1999, Genes & development.

[14]  Michael Karin,et al.  Positive and Negative Regulation of IκB Kinase Activity Through IKKβ Subunit Phosphorylation , 1999 .

[15]  S. Akira,et al.  Limb and skin abnormalities in mice lacking IKKalpha. , 1999, Science.

[16]  T. Deerinck,et al.  Abnormal Morphogenesis But Intact IKK Activation in Mice Lacking the IKKα Subunit of IκB Kinase , 1999 .

[17]  Ebrahim Zandi,et al.  Direct Phosphorylation of IκB by IKKα and IKKβ: Discrimination Between Free and NF-κB-Bound Substrate , 1998 .

[18]  G. Martin,et al.  The roles of FGFs in the early development of vertebrate limbs. , 1998, Genes & development.

[19]  David M. Rothwarf,et al.  A cytokine-responsive IκB kinase that activates the transcription factor NF-κB , 1997, Nature.

[20]  S. Hubbard,et al.  Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. , 1997, Science.

[21]  D. Donoghue,et al.  FGFR activation in skeletal disorders: too much of a good thing. , 1997, Trends in genetics : TIG.

[22]  L. Niswander,et al.  Requirement for BMP Signaling in Interdigital Apoptosis and Scale Formation , 1996, Science.

[23]  B. Hogan,et al.  Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. , 1995, Genes & development.

[24]  J. Martín,et al.  The paired-like homeo box gene MHox is required for early events of skeletogenesis in multiple lineages. , 1995, Genes & development.

[25]  N. Shikata,et al.  Immunohistochemical staining patterns of keratins in normal oesophageal epithelium and carcinoma of the oesophagus , 1995, Histopathology.

[26]  E. Fuchs,et al.  Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[27]  B. Hogan,et al.  Mice lacking Bmp6 function. , 1998, Developmental genetics.

[28]  Jane A. Langdale,et al.  In situ Hybridization , 1994 .

[29]  N. K. Wessells Tissue interactions and development , 1973 .

[30]  T. W. Torrey Morphogenesis of the vertebrates , 1971 .