Management of Hyperbilirubinemia in Newborns: Measuring Performance Using a Benchmarking Model

BACKGROUND Accreditors hold hospitals accountable for harm from serious newborn hyperbilirubinemia, yet standards for evaluating performance in prevention are lacking. OBJECTIVE We confirmed prognostic variables for newborn hyperbilirubinemia and developed a benchmarking model for self-evaluation of hyperbilirubinemia management. METHODS We conducted a 3-year prospective cohort study in the Henry Ford Health System (HFHS) on 5507 healthy newborns of >or=35 weeks' gestational age. HFHS follows a rigorous protocol for hyperbilirubinemia management. Defining hyperbilirubinemia as age-specific levels of total serum bilirubin exceeding American Academy of Pediatrics criteria for considering phototherapy and severe hyperbilirubinemia as total serum bilirubin >or=20 mg/dL, we used logistic and Poisson regressions to determine predictors and estimate parameters for a benchmarking model. We compared incidence rates for severe hyperbilirubinemia from HFHS to aggregate data from 11 hospitals reported to have less rigorous management. RESULTS Newborns were 52.9% black, 14.4% white, 24.3% Latino, and 2.4% Asian; 30% were exclusively and 28% partially breastfed. Regression analyses revealed associations for hyperbilirubinemia and severe hyperbilirubinemia with black mothers (negative) and exclusive or partial breastfeeding and younger gestational age (positive). Male newborns and older mothers were also associated with severe hyperbilirubinemia. For all 5 variables, we found a lower risk for severe hyperbilirubinemia at HFHS than in the comparison hospital group. To compare hospitals, we developed a benchmarking model for incidence of hyperbilirubinemia adjusting for race, feeding method, and gestational age. CONCLUSIONS Hospitals with access to newborns' inpatient and postdischarge data can use our benchmarking model to compare their management of hyperbilirubinemia with a reference population that received rigorous care.

[1]  V. Bhutani,et al.  System-based approach to management of neonatal jaundice and prevention of kernicterus. , 2002, The Journal of pediatrics.

[2]  G. W. Gross,et al.  Cost-effective Imaging Approach to the Nonbilious Vomiting Infant , 1999, Pediatrics.

[3]  M. J. Maisels,et al.  Management of hyperbilirubinemia in newborns: measuring performance using a benchmarking model. , 2004, Pediatrics.

[4]  Aap Subcommittee on Neonatal Hyperbilirubinemia Neonatal jaundice and kernicterus. , 2001, Pediatrics.

[5]  T B Newman,et al.  Frequency of neonatal bilirubin testing and hyperbilirubinemia in a large health maintenance organization. , 1999, Pediatrics.

[6]  Subcommittee on Hyperbilirubinemia Practice Parameter: Management of Hyperbilirubinemia in the Healthy Term Newborn , 1994, Pediatrics.

[7]  G. Avery Neonatology: Pathophysiology and management of the newborn , 1981 .

[8]  G. Escobar,et al.  Prediction and prevention of extreme neonatal hyperbilirubinemia in a mature health maintenance organization. , 2000, Archives of pediatrics & adolescent medicine.

[9]  M. J. Maisels,et al.  Length of stay, jaundice, and hospital readmission. , 1998, Pediatrics.

[10]  R. Schumacher,et al.  The effect of early discharge and other factors on readmission rates of newborns. , 1996, Archives of pediatrics & adolescent medicine.

[11]  A. Schneider Breast milk jaundice in the newborn. A real entity. , 1986, JAMA.

[12]  V. Bhutani,et al.  Predictive Ability of a Predischarge Hour-specific Serum Bilirubin for Subsequent Significant Hyperbilirubinemia in Healthy Term and Near-term Newborns , 1999, Pediatrics.

[13]  A. Fanaroff,et al.  Prediction of hyperbilirubinemia in near-term and term infants. , 2001, Journal of perinatology : official journal of the California Perinatal Association.