论文信息 - Circular RNAs: splicing's enigma variations

Circular RNAs: splicing's enigma variations

Nature advance online publication February272013; doi:10.1038/nature11993 Nature advance online publication February272013; doi:10.1038/nature11928 Circular (circ)RNAs are to transcriptomics what the famous hidden musical theme is to Elgar's Enigma Variations: woven into the entire composition but not unambiguously identified or understood by scholars to this day. Now, two studies (Hansen et al, 2013; Memczak et al, 2013) have made substantial progress in both, identifying thousands of circRNAs and beginning to crack the enigma of their cellular function, by demonstrating that the circRNAs CiRS-7/CDR1as and SRY function as natural and highly stable sponges for specific microRNAs.

Thomas Preiss | M. Hentze | T. Preiss | Matthias W Hentze

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