Segmentation of lumen and outer wall of abdominal aortic aneurysms from 3D black‐blood MRI with a registration based geodesic active contour model

HighlightsMR image segmentation is performed on abdominal aortic aneurysm lumen and outer wall.Novel segmentation is proposed using image registration and shape terms in the model.The repeatability and reproducibility of the proposed method are validated. &NA; Segmentation of the geometric morphology of abdominal aortic aneurysm is important for interventional planning. However, the segmentation of both the lumen and the outer wall of aneurysm in magnetic resonance (MR) image remains challenging. This study proposes a registration based segmentation methodology for efficiently segmenting MR images of abdominal aortic aneurysms. The proposed methodology first registers the contrast enhanced MR angiography (CE‐MRA) and black‐blood MR images, and then uses the Hough transform and geometric active contours to extract the vessel lumen by delineating the inner vessel wall directly from the CE‐MRA. The proposed registration based geometric active contour is applied to black‐blood MR images to generate the outer wall contour. The inner and outer vessel wall are then fused presenting the complete vessel lumen and wall segmentation. The results obtained from 19 cases showed that the proposed registration based geometric active contour model was efficient and comparable to manual segmentation and provided a high segmentation accuracy with an average Dice value reaching 89.79%.

[1]  Max A. Viergever,et al.  Interactive segmentation of abdominal aortic aneurysms in CTA images , 2004, Medical Image Anal..

[2]  Laurent Navarro,et al.  Segmentation of the thrombus of giant intracranial aneurysms from CT angiography scans with lattice Boltzmann method , 2014, Medical Image Anal..

[3]  Joe Y. Chang,et al.  Validation of an accelerated ‘demons’ algorithm for deformable image registration in radiation therapy , 2005, Physics in medicine and biology.

[4]  David A Bluemke,et al.  Using MRI to assess aortic wall thickness in the multiethnic study of atherosclerosis: distribution by race, sex, and age. , 2004, AJR. American journal of roentgenology.

[5]  Ender A Finol,et al.  Semiautomatic vessel wall detection and quantification of wall thickness in computed tomography images of human abdominal aortic aneurysms. , 2010, Medical physics.

[6]  R. Balaban,et al.  Arterial wall MRI characteristics are associated with elevated serum markers of inflammation in humans , 2001, Journal of magnetic resonance imaging : JMRI.

[7]  Boudewijn P F Lelieveldt,et al.  Automatic vessel wall contour detection and quantification of wall thickness in in‐vivo MR images of the human aorta , 2006, Journal of magnetic resonance imaging : JMRI.

[8]  Marcel Breeuwer,et al.  Segmentation of thrombus in abdominal aortic aneurysms from CTA with nonparametric statistical grey level appearance modeling , 2005, IEEE Transactions on Medical Imaging.

[9]  S C Whitaker,et al.  Imaging of abdominal aortic aneurysm before and after endoluminal stent-graft repair. , 2001, European journal of radiology.

[10]  Calum Gray,et al.  Abdominal Aortic Aneurysm Growth Predicted by Uptake of Ultrasmall Superparamagnetic Particles of Iron Oxide: A Pilot Study , 2011, Circulation. Cardiovascular imaging.

[11]  Nahum Kiryati,et al.  Prior-based Segmentation and Shape Registration in the Presence of Perspective Distortion , 2007, International Journal of Computer Vision.

[12]  Max A. Viergever,et al.  Active-shape-model-based segmentation of abdominal aortic aneurysms in CTA images , 2002, SPIE Medical Imaging.

[13]  L. R. Dice Measures of the Amount of Ecologic Association Between Species , 1945 .

[14]  G. Upchurch,et al.  Abdominal aortic aneurysm. , 2006, American family physician.

[15]  S. Travis,et al.  Endovascular AAA repair: Classification of aneurysm sac volumetric change using spiral computed tomo , 2002 .

[16]  Mark D. Huffman,et al.  Executive Summary: Heart Disease and Stroke Statistics—2015 Update A Report From the American Heart Association , 2011, Circulation.

[17]  J. Gillard,et al.  3D high-resolution contrast enhanced MRI of carotid atheroma--a technical update. , 2014, Magnetic resonance imaging.

[18]  Guillermo Sapiro,et al.  Geodesic Active Contours , 1995, International Journal of Computer Vision.

[19]  Yiu-Cho Chung,et al.  T1‐weighted–SPACE dark blood whole body magnetic resonance angiography (DB‐WBMRA): Initial experience , 2010, Journal of magnetic resonance imaging : JMRI.

[20]  J. Blankensteijn,et al.  Maximal aneurysm diameter follow-up is inadequate after endovascular abdominal aortic aneurysm repair. , 2000, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[21]  T. Leiner,et al.  Abdominal aortic aneurysms with high thrombus signal intensity on magnetic resonance imaging are associated with high growth rate. , 2014, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[22]  M. Egger,et al.  Risk factors for asymptomatic abdominal aortic aneurysm: systematic review and meta-analysis of population-based screening studies. , 2004, European journal of public health.

[23]  S. Travis,et al.  Endovascular AAA repair: classification of aneurysm sac volumetric change using spiral computed tomographic angiography. , 2002, Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists.

[24]  M. Fillinger Screening for abdominal aortic aneurysm: recommendation statement. , 2006, Annals of internal medicine.

[25]  D. Saloner,et al.  Isotropic 3D black blood MRI of abdominal aortic aneurysm wall and intraluminal thrombus. , 2016, Magnetic resonance imaging.

[26]  Chunming Li,et al.  Distance Regularized Level Set Evolution and Its Application to Image Segmentation , 2010, IEEE Transactions on Image Processing.

[27]  Guy Courbebaisse,et al.  Segmentation of giant cerebral aneurysms using a multilevel object detection scheme based on lattice Boltzmann method , 2011, 2011 IEEE International Conference on Signal Processing, Communications and Computing (ICSPCC).

[28]  Sven Loncaric,et al.  3-D deformable model for abdominal aortic aneurysm segmentation from CT images , 2000, IWISPA 2000. Proceedings of the First International Workshop on Image and Signal Processing and Analysis. in conjunction with 22nd International Conference on Information Technology Interfaces. (IEEE.

[29]  Jean-Philippe Thirion,et al.  Image matching as a diffusion process: an analogy with Maxwell's demons , 1998, Medical Image Anal..

[30]  Li Feng,et al.  Highly-accelerated self-gated free-breathing 3D cardiac cine MRI: validation in assessment of left ventricular function , 2017, Magnetic Resonance Materials in Physics, Biology and Medicine.

[31]  S. Napel,et al.  An abdominal aortic aneurysm segmentation method: level set with region and statistical information. , 2006, Medical physics.

[32]  Aaron Fenster,et al.  Joint segmentation of lumen and outer wall from femoral artery MR images: Towards 3D imaging measurements of peripheral arterial disease , 2015, Medical Image Anal..

[33]  B. Chopard,et al.  A spatio-temporal model for spontaneous thrombus formation in cerebral aneurysms , 2015, bioRxiv.

[34]  D. Altman,et al.  Measuring agreement in method comparison studies , 1999, Statistical methods in medical research.

[35]  Guy Courbebaisse,et al.  Multilevel segmentation of intracranial aneurysms in CT angiography images. , 2016, Medical physics.

[36]  M. Schocke,et al.  Serial CT Volume Measurements after Endovascular Aortic Aneurysm Repair , 2001, Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists.