Characterization and engineering of the Lrp/AsnC family regulator SACE_5717 for erythromycin overproduction in Saccharopolyspora erythraea
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Yansheng Wang | Hang Wu | Buchang Zhang | Weiyun Wang | Lixin Zhang | Jing Liu | Yunfu Chen | Long Li | Endong Yang
[1] Yansheng Wang,et al. Transcriptome-guided target identification of the TetR-like regulator SACE_5754 and engineered overproduction of erythromycin in Saccharopolyspora erythraea , 2019, Journal of biological engineering.
[2] Linhong Deng,et al. SAV4189, a MarR-Family Regulator in Streptomyces avermitilis, Activates Avermectin Biosynthesis , 2018, Front. Microbiol..
[3] B. Ye,et al. PccD Regulates Branched-Chain Amino Acid Degradation and Exerts a Negative Effect on Erythromycin Production in Saccharopolyspora erythraea , 2018, Applied and Environmental Microbiology.
[4] H. Rassi,et al. Overproduction of Erythromycin by Ultraviolet Mutagenesis and Expression of ermE Gene in Saccharopolyspora erythraea. , 2017, Assay and drug development technologies.
[5] J. Li,et al. Characterization of an Lrp/AsnC family regulator SCO3361, controlling actinorhodin production and morphological development in Streptomyces coelicolor , 2017, Applied Microbiology and Biotechnology.
[6] E. Isogai,et al. Expression of the alaE gene is positively regulated by the global regulator Lrp in response to intracellular accumulation of l-alanine in Escherichia coli. , 2017, Journal of bioscience and bioengineering.
[7] E. Peeters,et al. The genome-scale DNA-binding profile of BarR, a β-alanine responsive transcription factor in the archaeon Sulfolobus acidocaldarius , 2016, BMC Genomics.
[8] Yuanyuan Pan,et al. A Regulatory Gene SCO2140 is Involved in Antibiotic Production and Morphological Differentiation of Streptomyces coelicolor A3(2) , 2016, Current Microbiology.
[9] M. Kinsella,et al. Analysis of the Impact of Rosuvastatin on Bacterial Mevalonate Production Using a UPLC-Mass Spectrometry Approach , 2016, Current Microbiology.
[10] Yansheng Wang,et al. Inactivation of SACE_3446, a TetR family transcriptional regulator, stimulates erythromycin production in Saccharopolyspora erythraea , 2016, Synthetic and systems biotechnology.
[11] Milton H. Saier,et al. The LysE Superfamily of Transport Proteins Involved in Cell Physiology and Pathogenesis , 2015, PloS one.
[12] Ying Wen,et al. Increasing Avermectin Production in Streptomyces avermitilis by Manipulating the Expression of a Novel TetR-Family Regulator and Its Target Gene Product , 2015, Applied and Environmental Microbiology.
[13] Yawei Zhao,et al. A stepwise increase in pristinamycin II biosynthesis by Streptomyces pristinaespiralis through combinatorial metabolic engineering. , 2015, Metabolic engineering.
[14] Qing-ting Bu,et al. Transcriptome-guided identification of SprA as a pleiotropic regulator in Streptomyces chattanoogensis , 2015, Applied Microbiology and Biotechnology.
[15] B. Ye,et al. Dissecting and engineering of the TetR family regulator SACE_7301 for enhanced erythromycin production in Saccharopolyspora erythraea , 2014, Microbial Cell Factories.
[16] B. Ye,et al. Genetics and Molecular Biology of Industrial Organisms Sace_3986, a Tetr Family Transcriptional Regulator, Negatively Controls Erythromycin Biosynthesis in Saccharopolyspora Erythraea , 2022 .
[17] L. Nielsen,et al. Re-annotation of the Saccharopolyspora erythraea genome using a systems biology approach , 2013, BMC Genomics.
[18] Gang Liu,et al. Molecular Regulation of Antibiotic Biosynthesis in Streptomyces , 2013, Microbiology and Molecular Reviews.
[19] N. Peixeiro,et al. Cis-regulatory logic in archaeal transcription. , 2013, Biochemical Society transactions.
[20] S. Muyldermans,et al. Expanded target and cofactor repertoire for the transcriptional activator LysM from Sulfolobus , 2013, Nucleic acids research.
[21] Z. Deng,et al. Genomic and transcriptomic insights into the thermo-regulated biosynthesis of validamycin in Streptomyces hygroscopicus 5008 , 2012, BMC Genomics.
[22] Honghai Wang,et al. Regulatory and pathogenesis roles of Mycobacterium Lrp/AsnC family transcriptional factors , 2011, Journal of cellular biochemistry.
[23] Xunduan Huang,et al. Identification of SACE_7040, a Member of TetR Family Related to the Morphological Differentiation of Saccharopolyspora erythraea , 2011, Current Microbiology.
[24] D. Charlier,et al. The Lrp Family of Transcription Regulators in Archaea , 2010, Archaea.
[25] J. Martín,et al. Engineering of regulatory cascades and networks controlling antibiotic biosynthesis in Streptomyces. , 2010, Current opinion in microbiology.
[26] J. Martín,et al. PimT, an amino acid exporter controls polyene production via secretion of the quorum sensing pimaricin-inducer PI-factor in Streptomyces natalensis , 2009, Microbial cell factories.
[27] C. Peano,et al. Phenotypes and gene expression profiles of Saccharopolyspora erythraea rifampicin-resistant (rif) mutants affected in erythromycin production , 2009, Microbial cell factories.
[28] D. Charlier,et al. Ss‐LrpB, a transcriptional regulator from Sulfolobus solfataricus, regulates a gene cluster with a pyruvate ferredoxin oxidoreductase‐encoding operon and permease genes , 2009, Molecular microbiology.
[29] C. Kao,et al. A key developmental regulator controls the synthesis of the antibiotic erythromycin in Saccharopolyspora erythraea , 2008, Proceedings of the National Academy of Sciences.
[30] Arkady B Khodursky,et al. Limited functional conservation of a global regulator among related bacterial genera: Lrp in Escherichia, Proteus and Vibrio , 2008, BMC Microbiology.
[31] Y. Zhuang,et al. Genetic Modulation of the Overexpression of Tailoring Genes eryK and eryG Leading to the Improvement of Erythromycin A Purity and Production in Saccharopolyspora erythraea Fermentation , 2008, Applied and Environmental Microbiology.
[32] K. Yokoyama,et al. Feast/famine regulation by transcription factor FL11 for the survival of the hyperthermophilic archaeon Pyrococcus OT3. , 2007, Structure.
[33] L. Hellman,et al. Electrophoretic mobility shift assay (EMSA) for detecting protein–nucleic acid interactions , 2007, Nature Protocols.
[34] S. Lee,et al. Metabolic engineering of Escherichia coli for the production of l-valine based on transcriptome analysis and in silico gene knockout simulation , 2007, Proceedings of the National Academy of Sciences.
[35] Markiyan Samborskyy,et al. Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338 , 2007, Nature Biotechnology.
[36] M. Merighi,et al. Identification of the DNA bases of a DNase I footprint by the use of dye primer sequencing on an automated capillary DNA analysis instrument. , 2006, Journal of biomolecular techniques : JBT.
[37] A. Demain,et al. Genetic improvement of processes yielding microbial products. , 2006, FEMS microbiology reviews.
[38] L. Ptitsyn,et al. The yeaS (leuE) gene of Escherichia coli encodes an exporter of leucine, and the Lrp protein regulates its expression , 2005, FEBS letters.
[39] N. P. Zakataeva,et al. Expression of Genes Encoding the RhtB Family Proteins Depends on the Global Regulator Lrp , 2005, Molecular Biology.
[40] M. Butler. Natural products to drugs: natural product-derived compounds in clinical trials. , 2005, Natural product reports.
[41] J. Westpheling,et al. The bkdR Gene of Streptomyces coelicolor Is Required for Morphogenesis and Antibiotic Production and Encodes a Transcriptional Regulator of a Branched-Chain Amino Acid Dehydrogenase Complex , 2005, Journal of bacteriology.
[42] V. Danilenko,et al. Biogenesis and Regulation of Biosynthesis of Erythromycins in Saccharopolyspora erythraea , 2004, Applied Biochemistry and Microbiology.
[43] C. Kao,et al. Reverse engineering of industrial pharmaceutical-producing actinomycete strains using DNA microarrays. , 2004, Metabolic engineering.
[44] Thijs J. G. Ettema,et al. The Lrp family of transcriptional regulators , 2003, Molecular microbiology.
[45] W. D. de Vos,et al. The Sulfolobus solfataricus Lrp-like Protein LysM Regulates Lysine Biosynthesis in Response to Lysine Availability* , 2002, The Journal of Biological Chemistry.
[46] Christine J. Martin,et al. Increasing the efficiency of heterologous promoters in actinomycetes. , 2002, Journal of molecular microbiology and biotechnology.
[47] M. Saier,et al. The LysE superfamily: topology of the lysine exporter LysE of Corynebacterium glutamicum, a paradyme for a novel superfamily of transmembrane solute translocators. , 1999, Journal of molecular microbiology and biotechnology.
[48] F. Schneider,et al. Relationship between valine, fatty acids, and spiramycin biosynthesis in Streptomyces ambofaciens. , 1994, Canadian journal of microbiology.
[49] Hang Wu,et al. Engineering of an Lrp family regulator SACE_Lrp improves erythromycin production in Saccharopolyspora erythraea. , 2017, Metabolic engineering.
[50] János Bérdy,et al. Bioactive microbial metabolites. , 2005, The Journal of antibiotics.
[51] C. Khosla,et al. Process development and metabolic engineering for the overproduction of natural and unnatural polyketides. , 2001, Advances in biochemical engineering/biotechnology.