I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection
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M. Bajénoff | M. Karin | T. Lawrence | H. Chi | J. Caamaño | Lionel Luron | M. Bébien | S. Mémet | Xuefeng Wu | M. Seed | A. Mancino | C. Fong | E. Johnson | M. Habbeddine | Marc Bajénoff
[1] P. Cohen,et al. Essential Role for IKKβ in Production of Type 1 Interferons by Plasmacytoid Dendritic Cells* , 2012, The Journal of Biological Chemistry.
[2] H. Chi,et al. Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function , 2012, Proceedings of the National Academy of Sciences of the United States of America.
[3] Noula Shembade,et al. The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1 , 2011, Nature Immunology.
[4] B. Becher,et al. NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses , 2011, The Journal of experimental medicine.
[5] P. Cohen,et al. Polyubiquitin Binding to Optineurin Is Required for Optimal Activation of TANK-binding Kinase 1 and Production of Interferon β* , 2011, The Journal of Biological Chemistry.
[6] M. Bajénoff,et al. Visualizing Early Splenic Memory CD8+ T Cells Reactivation against Intracellular Bacteria in the Mouse , 2010, PloS one.
[7] T. Kaisho,et al. Cutting Edge: Critical Role of IκB Kinase α in TLR7/9-Induced Type I IFN Production by Conventional Dendritic Cells , 2010, The Journal of Immunology.
[8] S. Akira,et al. Pattern Recognition Receptors and Inflammation , 2010, Cell.
[9] A. Iwasaki,et al. Regulation of Adaptive Immunity by the Innate Immune System , 2010, Science.
[10] B. Pulendran,et al. Modulation of adaptive immunity with Toll-like receptors. , 2009, Seminars in immunology.
[11] A. Hoffmann,et al. A Unifying Model for the Selective Regulation of Inducible Transcription by CpG Islands and Nucleosome Remodeling , 2009, Cell.
[12] T. Taniguchi,et al. Characterization of the Interferon-Producing Cell in Mice Infected with Listeria monocytogenes , 2009, PLoS pathogens.
[13] J. Keats,et al. Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling , 2008, Nature Immunology.
[14] David A. Hume,et al. Macrophages as APC and the Dendritic Cell Myth , 2008, The Journal of Immunology.
[15] R. Steinman. Dendritic cells in vivo: a key target for a new vaccine science. , 2008, Immunity.
[16] S. Fischer,et al. IKKalpha is required to maintain skin homeostasis and prevent skin cancer. , 2008, Cancer cell.
[17] Marc Lecuit. Human listeriosis and animal models. , 2007, Microbes and infection.
[18] B. Reizis,et al. Notch–RBP-J signaling controls the homeostasis of CD8− dendritic cells in the spleen , 2007, The Journal of experimental medicine.
[19] Qiang Sun,et al. The NEMO adaptor bridges the nuclear factor-κB and interferon regulatory factor signaling pathways , 2007, Nature Immunology.
[20] B. Liu,et al. Proinflammatory Stimuli Induce IKKα-Mediated Phosphorylation of PIAS1 to Restrict Inflammation and Immunity , 2007, Cell.
[21] Michael Karin,et al. Regulation and Function of IKK and IKK-Related Kinases , 2006, Science's STKE.
[22] K. Honda,et al. IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors , 2006, Nature Reviews Immunology.
[23] S. Akira,et al. IκB kinase-α is critical for interferon-α production induced by Toll-like receptors 7 and 9 , 2006, Nature.
[24] J. Hiscott,et al. IRF-3 releases its inhibitions. , 2005, Structure.
[25] Inder M. Verma,et al. Enhanced NF-κB activation and cellular function in macrophages lacking IκB kinase 1 (IKK1) , 2005 .
[26] Christophe Caux,et al. A type I interferon autocrine–paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells , 2005, The Journal of experimental medicine.
[27] Toby Lawrence,et al. IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation , 2005, Nature.
[28] C. Sousa,et al. Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function , 2005, Nature Immunology.
[29] B. Aronow,et al. Activation of IKKα target genes depends on recognition of specific κB binding sites by RelB:p52 dimers , 2004 .
[30] E. Pamer. Immune responses to Listeria monocytogenes , 2004, Nature Reviews Immunology.
[31] M. Karin,et al. The two NF-κB activation pathways and their role in innate and adaptive immunity , 2004 .
[32] F. Inagaki,et al. Identification of Ser-386 of Interferon Regulatory Factor 3 as Critical Target for Inducible Phosphorylation That Determines Activation* , 2004, Journal of Biological Chemistry.
[33] Tak W. Mak,et al. Toll-like receptor 3-mediated activation of NF-κB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-β , 2004 .
[34] S. Akira,et al. Selective contribution of IFN-α/β signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[35] S. Akira,et al. Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway , 2003, Science.
[36] Guo-Ping Zhou,et al. Triggering the Interferon Antiviral Response Through an IKK-Related Pathway , 2003, Science.
[37] J. Ninomiya-Tsuji,et al. A Resorcylic Acid Lactone, 5Z-7-Oxozeaenol, Prevents Inflammation by Inhibiting the Catalytic Activity of TAK1 MAPK Kinase Kinase* , 2003, The Journal of Biological Chemistry.
[38] M. Nierenstein,et al. β‐Resorcylic Acid , 2003 .
[39] M. Bevan,et al. Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help , 2003, Science.
[40] Steffen Jung,et al. In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. , 2002, Immunity.
[41] E. Schmidt,et al. IKKα Provides an Essential Link between RANK Signaling and Cyclin D1 Expression during Mammary Gland Development , 2001, Cell.
[42] S. Akira,et al. Toll-like receptors control activation of adaptive immune responses , 2001, Nature Immunology.
[43] Michael Karin,et al. Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway , 2001, Science.
[44] Zhijian J. Chen,et al. TAK1 is a ubiquitin-dependent kinase of MKK and IKK , 2001, Nature.
[45] D. Goeddel,et al. Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice , 2001, Science.
[46] A. Sher,et al. CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. , 2000, Immunity.
[47] T. Taniguchi,et al. Distinct and Essential Roles of Transcription Factors IRF-3 and IRF-7 in Response to Viruses for IFN-α/β Gene Induction , 2000 .
[48] C. Hunter,et al. The NF-kappa B family member RelB is required for innate and adaptive immunity to Toxoplasma gondii. , 1999, Journal of immunology.
[49] T. Deerinck,et al. The IKKβ Subunit of IκB Kinase (IKK) is Essential for Nuclear Factor κB Activation and Prevention of Apoptosis , 1999, The Journal of experimental medicine.
[50] J. Hiscott,et al. Structural and Functional Analysis of Interferon Regulatory Factor 3: Localization of the Transactivation and Autoinhibitory Domains , 1999, Molecular and Cellular Biology.
[51] A. D'amico,et al. RelB Is Essential for the Development of Myeloid-Related CD8α− Dendritic Cells but Not of Lymphoid-Related CD8α+ Dendritic Cells , 1998 .
[52] J. Hiscott,et al. Virus-Dependent Phosphorylation of the IRF-3 Transcription Factor Regulates Nuclear Translocation, Transactivation Potential, and Proteasome-Mediated Degradation , 1998, Molecular and Cellular Biology.
[53] C. Snapper,et al. Nuclear Factor (NF)-κB2 (p100/p52) Is Required for Normal Splenic Microarchitecture and B Cell–mediated Immune Responses , 1998, The Journal of experimental medicine.
[54] Zhe‐Xi Luo,et al. A new symmetrodont mammal from China and its implications for mammalian evolution , 1997, Nature.
[55] E. Zandi,et al. The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation. , 1997, Cell.
[56] E. Zandi,et al. The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation , 1997, Cell.
[57] D. Carrasco,et al. Gastric Hyperplasia and Increased Proliferative Responses of Lymphocytes in Mice Lacking the COOH-terminal Ankyrin Domain of NF-κB2 , 1997, The Journal of experimental medicine.
[58] STRUCTURAL AND FUNCTIONAL ANALYSIS , 2015 .
[59] G. Cheng,et al. NF-κB and innate immunity. , 2011, Current topics in microbiology and immunology.
[60] S. Akira,et al. Immunoadjuvant effects of polyadenylic:polyuridylic acids through TLR3 and TLR7. , 2008, International immunology.
[61] S. Akira,et al. IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9. , 2006, Nature.
[62] I. Verma,et al. Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1). , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[63] Toby Lawrence,et al. IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. , 2005, Nature.
[64] M. Karin,et al. The two NF-kappaB activation pathways and their role in innate and adaptive immunity. , 2004, Trends in immunology.
[65] B. Aronow,et al. Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers. , 2004, The EMBO journal.
[66] T. Mak,et al. Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[67] S. Akira,et al. Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection. , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[68] M. Karin,et al. Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. , 2001, Science.
[69] D. Goeddel,et al. Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice. , 2001, Science.
[70] E. Schmidt,et al. IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development. , 2001, Cell.
[71] T. Taniguchi,et al. Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction. , 2000, Immunity.
[72] M. Karin,et al. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. , 2000, Annual review of immunology.
[73] A. D'amico,et al. RelB is essential for the development of myeloid-related CD8alpha- dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells. , 1998, Immunity.
[74] L. Sokoloff,et al. Animal models of rheumatoid arthritis. , 1984, International review of experimental pathology.