Predictive Value of Heart Rate Recovery after Exercise Testing in Addition to Brain Natriuretic Peptide Levels in Ambulatory Patients with Nonischemic Dilated Cardiomyopathy

Background: Heart rate recovery (HRR) is related to autonomic function and is a prognostic marker in cardiovascular disease. We sought to investigate the clinical utility of HRR in addition to BNP levels in ambulatory outpatients with nonischemic dilated cardiomyopathy (NICM).

[1]  M. Peberdy,et al.  Prognostic value of heart rate recovery in patients with heart failure. , 2006, American heart journal.

[2]  Alan S. Pearlman,et al.  ACC/AHA/ASE 2003 Guideline Update for the Clinical Application of Echocardiography: summary article. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/ASE Committee to Update the 1997 Guidelines for the Clinical Application of Echoca , 2003, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[3]  L. Horowitz,et al.  Prognosis in severe heart failure: relation to hemodynamic measurements and ventricular ectopic activity. , 1983, Journal of the American College of Cardiology.

[4]  M. A. Plant Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality , 1991 .

[5]  D. Faxon,et al.  ACC/AHA/ASE 2003 guideline update for the clinical application of echocardiography--summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/ASE Committee to Update the 1997 Guidelines for the Clinical Application of Echoca , 2003, Journal of the American College of Cardiology.

[6]  K. Umeno,et al.  Time course of sympathovagal imbalance and left ventricular dysfunction in conscious dogs with heart failure. , 1998, Journal of applied physiology.

[7]  B. Massie,et al.  Correlates and prognostic implication of exercise capacity in chronic congestive heart failure. , 1985, The American journal of cardiology.

[8]  M. Hori,et al.  Vagally mediated heart rate recovery after exercise is accelerated in athletes but blunted in patients with chronic heart failure. , 1994, Journal of the American College of Cardiology.

[9]  J. Ornato,et al.  ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult—Summary Article , 2005 .

[10]  A. Cohen-Solal,et al.  Plasma brain natriuretic peptide-guided therapy to improve outcome in heart failure: the STARS-BNP Multicenter Study. , 2007, Journal of the American College of Cardiology.

[11]  A Camerini,et al.  [Heart rate recovery and treadmill exercise score as predictors of mortality in patients referred for exercise ECG]. , 2001, Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology.

[12]  Brian Olshansky,et al.  Parasympathetic nervous system and heart failure: pathophysiology and potential implications for therapy. , 2008, Circulation.

[13]  F. Martinez,et al.  ATS/ACCP Statement on cardiopulmonary exercise testing. , 2003, American journal of respiratory and critical care medicine.

[14]  Pamela S Douglas,et al.  Acc/aha/ase 2003 Guideline Update for the Clinical Application of Echocardiography: Summary Article a Report of the American College of Cardiology/american Heart Association Task Force on Practice Guidelines (acc/aha/ase Committee to Update the 1997 Guidelines for the Clinical Application of Echocar , 2003 .

[15]  A. Kadish,et al.  Parasympathetic Effects on Heart Rate Recovery after Exercise , 2004, Journal of Investigative Medicine.

[16]  A. Maisel,et al.  Natriuretic peptides. , 2007, Journal of the American College of Cardiology.

[17]  John A Spertus,et al.  Confirmation of a heart failure epidemic: findings from the Resource Utilization Among Congestive Heart Failure (REACH) study. , 2002, Journal of the American College of Cardiology.

[18]  B Maisch,et al.  Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the Definition and Classification of cardiomyopathies. , 1996, Circulation.

[19]  K. Swedberg,et al.  Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group. , 1990, Circulation.

[20]  J. Goldberger,et al.  Assessment of autonomic function in cardiovascular disease: physiological basis and prognostic implications. , 2008, Journal of the American College of Cardiology.

[21]  Eugene H Blackstone,et al.  Heart rate recovery after exercise is a predictor of mortality, independent of the angiographic severity of coronary disease. , 2003, Journal of the American College of Cardiology.

[22]  J. Cohn,et al.  Cardiac remodeling--concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling. , 2000, Journal of the American College of Cardiology.

[23]  M. Lauer,et al.  Heart-rate recovery immediately after exercise as a predictor of mortality. , 1999, The New England journal of medicine.

[24]  L. Fisher,et al.  Changes in Brain Natriuretic Peptide and Norepinephrine Over Time and Mortality and Morbidity in the Valsartan Heart Failure Trial (Val-HeFT) , 2003, Circulation.

[25]  T. Inomata,et al.  Prognostic utility of B-type natriuretic peptide assessment in stable low-risk outpatients with nonischemic cardiomyopathy after decompensated heart failure. , 2008, Journal of the American College of Cardiology.

[26]  A. Maisel,et al.  State-of-the-Art PaperNatriuretic Peptides , 2007 .