Chemical composition and antibacterial activity of the essential oil from Mentha suaveolens ssp. insularis (Req.) Greuter

A detailed analysis of Mentha suaveolens ssp. insularis (Req.) Greuter essential oil (EO) and hydrolate extract (HE) was carried out by combination of GC–RI, GC–MS and 13C-NMR spectroscopy. After fractionation by column chromatography, 51 components of the EO and 27 components of the HE, accounting for 96.1% and 98.3%, respectively, were identified. The main components were pulegone (44.4% and 14.8%) and cis-cis-p-menthenolide (27.3% and 67.3%). This α-methylen-γ-butyrolactone, reported for the first time as a natural product, was isolated and its structure elucidated by 1D and 2D NMR spectroscopy. Both EO and HE exhibited a fair antibacterial activity against Staphylococcus aureus and Bacillus cereus. Copyright © 2008 John Wiley & Sons, Ltd.

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