Detection of hepatocellular carcinoma‐ specific alpha‐fetoprotein by isoelectric focusing

Background. Serum alpha‐fetoprotein (AFP) is elevated in up to 80% of patients with hepatocellular carcinoma (HCC). Modestly raised AFP levels (10‐400 ng/ml) are also found in patients with nonmalignant liver diseases. In the present study, isoelectric focusing of AFP was used to differentiate the AFP found in patients with HCC.

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