Functional specializations in human cerebral cortex analyzed using the visible man surface‐based atlas

We used surface‐based representations to analyze functional specializations in the human cerebral cortex. A computerized reconstruction of the cortical surface of the Visible Man digital atlas was generated and transformed to the Talairach coordinate system. This surface was also flattened and used to establish a surface‐based coordinate system that respects the topology of the cortical sheet. The linkage between two‐dimensional and three‐dimensional representations allows the locations of published neuroimaging activation foci to be stereotaxically projected onto the Visible Man cortical flat map. An analysis of two activation studies related to the hearing and reading of music and of words illustrates how this approach permits the systematic estimation of the degree of functional segregation and of potential functional overlap for different aspects of sensory processing. Hum. Brain Mapping 5:233–237, 1997. © 1997 Wiley‐Liss, Inc.

[1]  Jack L. Lancaster,et al.  A modality‐independent approach to spatial normalization of tomographic images of the human brain , 1995 .

[2]  M. Torrens Co-Planar Stereotaxic Atlas of the Human Brain—3-Dimensional Proportional System: An Approach to Cerebral Imaging, J. Talairach, P. Tournoux. Georg Thieme Verlag, New York (1988), 122 pp., 130 figs. DM 268 , 1990 .

[3]  M. Raichle,et al.  A Stereotactic Method of Anatomical Localization for Positron Emission Tomography , 1985, Journal of computer assisted tomography.

[4]  D. C. Van Essen,et al.  A surface reconstruction and cortical flat map of the Visible Human linked to the Talairach atlas , 1996, NeuroImage.

[5]  D. V. van Essen,et al.  Computerized Mappings of the Cerebral Cortex: A Multiresolution Flattening Method and a Surface-Based Coordinate System , 1996, Journal of Cognitive Neuroscience.

[6]  P. T. Fox,et al.  Positron emission tomographic studies of the cortical anatomy of single-word processing , 1988, Nature.

[7]  D. V. van Essen,et al.  Structural and Functional Analyses of Human Cerebral Cortex Using a Surface-Based Atlas , 1997, The Journal of Neuroscience.

[8]  小野 道夫,et al.  Atlas of the Cerebral Sulci , 1990 .

[9]  G. Bruyn Atlas of the Cerebral Sulci, M. Ono, S. Kubik, Chad D. Abernathey (Eds.). Georg Thieme Verlag, Stuttgart, New York (1990), 232, DM 298 , 1990 .

[10]  J Sergent,et al.  Distributed neural network underlying musical sight-reading and keyboard performance. , 1992, Science.