Current Knowledge in Soybean Composition

Abstract The soybean [Glycine max (L.) Merr.] is grown worldwide for its high protein and oil contents. Characterization of soybean seed components lends itself to understanding how soybean production can meet the needs of a growing world population. For this article, literature was reviewed and condensed to create a well-rounded picture of the current understanding of structural, functional, and nutritional properties of soybean components. Natural variation in soybean protein, lipid, and carbohydrate components, as well as the minor constituents phytic acid and isoflavones, are mentioned. Environment- or genetic-induced shifts in natural variation are described with respect to nutrition and functional improvements in soybean.

[1]  N. Nielsen,et al.  The Biochemistry and Cell Biology of Embryo Storage Proteins , 1997 .

[2]  G. Robertson,et al.  Agronomic management system and precipitation effects on soybean oil and fatty acid profiles , 2009 .

[3]  M. Weih Trade-offs in plants and the prospects for breeding using modern biotechnology , 2003 .

[4]  C. R. Weber Inheritance and interrelation of some agronomic and chemical characters in an interspecific cross in soybeans, Glycine max x G. ussuriensis , 1950 .

[5]  A. Rani,et al.  Influence of growing environment on the biochemical composition and physical characteristics of soybean seed , 2006 .

[6]  Y. Takagi,et al.  Inheritance of high oleic acid content in the seed oil of soybean mutant M23 , 1996, Theoretical and Applied Genetics.

[7]  P. Pour,et al.  Inhibition of skin carcinomas but not papillomas by sphingosine, N-methylsphingosine, and N-acetylsphingosine. , 1998, Nutrition and cancer.

[8]  J. Hazebroek,et al.  Tocopherols in breeding lines and effects of planting location, fatty acid composition, and temperature during development , 1999 .

[9]  E. Cahoon,et al.  Characterization of Tocopherol Cyclases from Higher Plants and Cyanobacteria. Evolutionary Implications for Tocopherol Synthesis and Function1 , 2003, Plant Physiology.

[10]  A. Rani,et al.  Sucrose and raffinose family oligosaccharides (RFOs) in soybean seeds as influenced by genotype and growing location. , 2010, Journal of agricultural and food chemistry.

[11]  C. Grieshop,et al.  Comparison of quality characteristics of soybeans from Brazil, China, and the United States. , 2001, Journal of agricultural and food chemistry.

[12]  Jan Hazebroek,et al.  Phytosterol accumulation in canola, sunflower, and soybean oils: Effects of genetics, planting location, and temperature , 2000 .

[13]  G. Srivastava,et al.  Phytic acid in Indian soybean: genotypic variability and influence of growing location , 2005 .

[14]  Influence of Locations and Planting Dates on Protein Composition of Soybean Lines with Modified Beta-Conglycinin and Glycinin Concentration , 2010 .

[15]  M. Friedman,et al.  Nutritional and health benefits of soy proteins. , 2001, Journal of agricultural and food chemistry.

[16]  Taro Masuda,et al.  Crystal structure of soybean 11S globulin: Glycinin A3B4 homohexamer , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[17]  Lawrence A. Johnson,et al.  Soybeans : chemistry, production, processing, and utilization , 2008 .

[18]  S. Tosh,et al.  Dietary fibres in pulse seeds and fractions: Characterization, functional attributes, and applications , 2010 .

[19]  M. Sugano Soy in health and disease prevention. , 2005 .

[20]  James E. Specht,et al.  Soybean response to water : A QTL analysis of drought tolerance , 2001 .

[21]  Pengyin Chen,et al.  Genetic diversity and association analysis of protein and oil content in food‐grade soybeans from Asia and the United States , 2010 .

[22]  E. E. Hartwig,et al.  Seed protein and its relationship to soluble sugars in soybean , 1997 .

[23]  S. Zeisel Choline: an important nutrient in brain development, liver function and carcinogenesis. , 1992, Journal of the American College of Nutrition.

[24]  I. Liener,et al.  Implications of antinutritional components in soybean foods. , 1994, Critical reviews in food science and nutrition.

[25]  T. Cheesbrough Changes in the Enzymes for Fatty Acid Synthesis and Desaturation during Acclimation of Developing Soybean Seeds to Altered Growth Temperature. , 1989, Plant physiology.

[26]  R. L. Anderson,et al.  Compositional Changes in Trypsin Inhibitors, Phytic Acid, Saponins and Isoflavones Related to Soybean Processing , 1995 .

[27]  H. Nguyen,et al.  Silencing of GmFAD3 gene by siRNA leads to low α-linolenic acids (18:3) of fad3-mutant phenotype in soybean [Glycine max (Merr.)] , 2008, Transgenic Research.

[28]  Bhupinder S. Farmaha,et al.  Soybean seed composition, aboveground growth, and nutrient accumulation with phosphorus and potassium fertilization in no-till and strip-till , 2012 .

[29]  D. Duvick,et al.  Inheritance of Reduced Palmitic Acid Content in Seed Oil of Soybean , 1991 .

[30]  Edgar B. Cahoon,et al.  Genetic Enhancement of Soybean Oil for Industrial Uses: Prospects and Challenges , 2003 .

[31]  P. Murphy 8 – Soybean Proteins , 2008 .

[32]  A. Kinney,et al.  A high-oleic-acid and low-palmitic-acid soybean: agronomic performance and evaluation as a feedstock for biodiesel. , 2009, Plant biotechnology journal.

[33]  W. Fehr,et al.  Agronomic and Seed Traits of Soybean Lines with Low–Phytate Phosphorus , 2005 .

[34]  K. Shibasaki,et al.  Major proteins of soybean seeds. Subunit structure of .beta.-conglycinin , 1978 .

[35]  S. Qiao,et al.  EFFECTS OF STACHYOSE ON PERFORMANCE, DIARRHOEA INCIDENCE AND INTESTINAL BACTERIA IN WEANLING PIGS , 2003, Archiv fur Tierernahrung.

[36]  S. Britz,et al.  Effect of temperature, elevated carbon dioxide, and drought during seed development on the isoflavone content of dwarf soybean [Glycine max (L.) Merrill] grown in controlled environments. , 2005, Journal of agricultural and food chemistry.

[37]  H. Krishnan Biochemistry and Molecular Biology of Soybean Seed Storage Proteins , 2000 .

[38]  R. Watson,et al.  Trans and other fatty acids: effects on endothelial functions. , 2009 .

[39]  A. Kinney,et al.  Ribozyme termination of RNA transcripts down-regulate seed fatty acid genes in transgenic soybean. , 2002, The Plant journal : for cell and molecular biology.

[40]  Y. L. Zhu,et al.  Identification of the soybean allergenic protein, Gly m Bd 30K, with the soybean seed 34-kDa oil-body-associated protein. , 1993, Bioscience, biotechnology, and biochemistry.

[41]  Lars-Åke Appelqvist,et al.  The chemistry and antioxidant properties of tocopherols and tocotrienols , 1996, Lipids.

[42]  J. W. Burton,et al.  Genetic Variability for Phytic Acid Phosphorus and Inorgaic Phosphorus in Seeds of Soybeans in Maturity Groups V, VI, and VII , 2006 .

[43]  T. Anai,et al.  Combining Ability in Loci for High Oleic and Low Linolenic Acids in Soybean , 2001 .

[44]  K. Kitamura,et al.  Malonyl isoflavone glycosides in soybean seeds (Glycine max Merrill) , 1991 .

[45]  A. Merrill,et al.  Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice. , 1994, The Journal of nutrition.

[46]  A. Mallarino,et al.  Phosphorus and Potassium Fertilization Effects on Soybean Seed Quality and Composition , 2013 .

[47]  A. Mengistu,et al.  Seed composition is influenced by irrigation regimes and cultivar differences in soybean , 2008, Irrigation Science.

[48]  G. Inglett Symposium : seed proteins , 1972 .

[49]  R. L. Bernard,et al.  USDA Soybean Genetic Collection: Isoline Collection , 1991 .

[50]  G. Malzer,et al.  Soybean Yield and Quality in Relation to Soil Properties , 2012 .

[51]  J. Boersma,et al.  New Mutations in a Delta-9-Stearoyl-Acyl Carrier Protein Desaturase Gene Associated with Enhanced Stearic Acid Levels in Soybean Seed , 2012 .

[52]  C. V. Morr,et al.  Solubility and Foaming Properties of Phytate‐Reduced Soy Protein Isolate , 1985 .

[53]  B. Berra,et al.  Dietary sphingolipids in colorectal cancer prevention. , 2002, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

[54]  I. Chung,et al.  Variation in isoflavone of soybean cultivars with location and storage duration. , 2003, Journal of agricultural and food chemistry.

[55]  W. Fehr,et al.  Agronomic and Seed Characteristics of Soybean with Reduced Raffinose and Stachyose , 2005 .

[56]  W. Fehr,et al.  Frying Performance of No-trans, Low-Linolenic Acid Soybean Oils , 2007 .

[57]  Oliver Yu,et al.  Accumulation of genistein and daidzein, soybean isoflavones implicated in promoting human health, is significantly elevated by irrigation. , 2004, Journal of agricultural and food chemistry.

[58]  R. Farré,et al.  Analysis of phytosterols in foods. , 2006, Journal of pharmaceutical and biomedical analysis.

[59]  K. Fujimoto,et al.  Identification of Soybean Varieties with High α-Tocopherol Content , 2005 .

[60]  K. Fujimoto,et al.  Effects of genetic variability and planting location on the phytosterol content and composition in soybean seeds , 2007 .

[61]  D. Briggs,et al.  Studies on the cold-insoluble fraction of the water-extractable soybean proteins. II. Factors influencing conformation changes in the 11 S component. , 1958, Archives of biochemistry and biophysics.

[62]  George C. Fahey,et al.  Chemical composition and protein quality comparisons of soybeans and soybean meals from five leading soybean-producing countries. , 2004 .

[63]  G. Rebetzke,et al.  Registration of N98–4445A Mid‐Oleic Soybean Germplasm Line , 2006 .

[64]  R. Watson Fatty acids in health promotion and disease causation. , 2009 .

[65]  M. Ishimoto,et al.  Recent advances in soybean transformation and their application to molecular breeding and genomic analysis , 2012, Breeding science.

[66]  D. M. Pharr,et al.  Galactinol synthase activity and soluble sugars in developing seeds of four soybean genotypes. , 1987, Plant physiology.

[67]  A. Robinson,et al.  Analysis of high yielding, early-planted soybean in Indiana. , 2009 .

[68]  Alan G. Taylor,et al.  Imbibitional Chilling Sensitivity and Soluble Carbohydrate Composition of Low Raffinose, Low Stachyose Soybean Seed , 2008 .

[69]  C. Hurburgh,et al.  Protein and oil patterns in U.S. and world soybean markets , 1990 .

[70]  R. Dixon,et al.  Biochemistry of Storage Carbohydrates in Green Plants , 1985 .

[71]  M. Sugano,et al.  Effects of dietary sphingolipids on levels of serum and liver lipids in rats , 1992 .

[72]  R. Yaklich beta-Conglycinin and glycinin in high-protein soybean seeds. , 2001, Journal of agricultural and food chemistry.

[73]  W. Fehr,et al.  Phospholipid fatty acid composition and stereospecific distribution of soybeans with a wide range of fatty acid composition , 1997 .

[74]  H. Taira Quality of Soybeans for Processed foods in Japan , 1990 .

[75]  R. Dewey,et al.  New Gene Combinations Governing Saturated and Unsaturated Fatty Acid Composition in Soybean , 2002 .

[76]  V. Raboy,et al.  Phytic Acid Levels in Seeds of Glycine max and G. soja as Influenced by Phosphorus Status , 1993 .

[77]  F. Below,et al.  Variation in Seed Total Phosphorus, Phytic Acid, Zinc, Calcium, Magnesium, and Protein among Lines of Glycine max and G. soja1 , 1984 .

[78]  J. Shanklin,et al.  Mutations in a Δ9–Stearoyl‐ACP‐Desaturase Gene Are Associated with Enhanced Stearic Acid Levels in Soybean Seeds , 2008 .

[79]  H. Jung,et al.  Analysis of forage fiber and cell walls in ruminant nutrition. , 1997, The Journal of nutrition.

[80]  Pat Baird,et al.  Health benefits of dietary fiber. , 2009, Nutrition reviews.

[81]  C. Kole,et al.  Genetics, Genomics, and Breeding of Soybean , 2010 .

[82]  J. Manjaya,et al.  Identification of low lectin mutants in soybean , 2008 .

[83]  S. Naeve,et al.  Year, Region, and Temperature Effects on the Quality of Minnesota's Soybean Crop , 2008 .

[84]  K. Kitamura,et al.  α-Subunit of β-Conglycinin, an Allergenic Protein Recognized by IgE Antibodies of Soybean-sensitive Patients with Atopic Dermatitis , 1995 .

[85]  W. Fehr,et al.  Agronomic and Seed Characteristics of Soybean Lines with Alleles for Modified Glycinin Concentration , 2010 .

[86]  Charles R. Hurburgh,et al.  Quality of US Soybean Meal Compared to the Quality of Soybean Meal from Other Origins , 2007 .

[87]  T. Hymowitz,et al.  Relationship Between the Content of Oil, Protein, and Sugar in Soybean Seed1 , 1972 .

[88]  E. Herman Soybean allergenicity and suppression of the immunodominant allergen , 2005 .

[89]  Monica A. Schmidt,et al.  Evaluation of Glycine Germplasm for Nulls of the Immunodominant Allergen P34/Gly m Bd 30k , 2006 .

[90]  T. Lyons Biotechnology in the feed industry , 1987 .

[91]  R. Shoemaker,et al.  Marker‐Assisted Selection for Elevated Concentrations of the α′ Subunit of β‐Conglycinin and Its Influence on Agronomic and Seed Traits of Soybean , 2013 .

[92]  J. Carreira,et al.  Purification and characterization of major inhalant allergens from soybean hulls , 1992, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[93]  R. Helm,et al.  Identification of peanut agglutinin and soybean trypsin inhibitor as minor legume allergens. , 1994, International archives of allergy and immunology.

[94]  A. H. Jensen,et al.  The limiting amino acids in soybean protein. , 1962 .

[95]  V. Raboy,et al.  Isolation of High Seed Inorganic P, Low‐Phytate Soybean Mutants , 2000 .

[96]  Ivana Vucenik,et al.  Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic. , 2003, The Journal of nutrition.

[97]  C. Arellano,et al.  Agronomic Effects of Mutations in Two Soybean Δ9–Stearoyl-Acyl Carrier Protein-Desaturases , 2013 .

[98]  C. Tsukamoto,et al.  Factors affecting isoflavone content in soybean seeds: changes in isoflavones, saponins, and composition of fatty acids at different temperatures during seed development , 1995 .

[99]  M. Westgate,et al.  Relationship between assimilate supply per seed during seed filling and soybean seed composition. , 2009 .

[100]  J. L. Cartter,et al.  Physiological Factors Affecting Composition of Soybeans: II. Response of Oil and Other Constituents of Soybeans to Temperature Under Controlled Conditions 1 , 1958 .

[101]  P. Wiatrak,et al.  Effect of Planting Date on Soybean Growth, Yield, and Grain Quality: Review , 2012 .

[102]  A. Olivera,et al.  Sphingolipids and the Balancing of Immune Cell Function: Lessons from the Mast Cell , 2005, The Journal of Immunology.

[103]  Fermentation of stachyose and raffinose by hind‐gut bacteria of the weanling pig , 1994 .

[104]  Albert H. Probst,et al.  Correlation of Agronomic Characters and Temperature with Seed Compositional Characters in Soybeans, as Influenced by Variety and Time of Planting 1 , 1952 .

[105]  P. Hasegawa,et al.  Differences in the fatty acid composition of soybean seed produced in northern and southern areas of the U.S.A. , 1985 .

[106]  A. Merrill,et al.  Sphingomyelin consumption suppresses aberrant colonic crypt foci and increases the proportion of adenomas versus adenocarcinomas in CF1 mice treated with 1,2-dimethylhydrazine: implications for dietary sphingolipids and colon carcinogenesis. , 1996, Cancer research.

[107]  M. Sugano Nutritional implications of soy. , 2006 .

[108]  Shiro Watanabe,et al.  A LONG-TERM FEEDING OF SPHINGOLIPIDS AFFECTED THE LEVELS OF PLASMA CHOLESTEROL AND HEPATIC TRIACYLGLYCEROL BUT NOT TISSUE PHOSPHOLIPIDS AND SPHINGOLIPIDS , 1997 .

[109]  I. Mateos-Aparicio,et al.  Soybean seeds and its by-product okara as sources of dietary fibre. Measurement by AOAC and Englyst methods. , 2008, Food chemistry.

[110]  X. Ren,et al.  Generation and characterization of two novel low phytate mutations in soybean (Glycine max L. Merr.) , 2007, Theoretical and Applied Genetics.

[111]  Edgar B Cahoon,et al.  Soybean Oil: Genetic Approaches for Modification of Functionality and Total Content1 , 2009, Plant Physiology.

[112]  J. Dardanelli,et al.  Water Deficit Effect on the Relationship between Temperature during the Seed Fill Period and Soybean Seed Oil and Protein Concentrations , 2009 .

[113]  S. Konno Changes in Chemical Composition of Soybean Seeds during Ripening , 1979 .

[114]  C. Rameau,et al.  Peas: Genetics, Molecular Biology and Biotechnology , 1993 .

[115]  F. Shahidi,et al.  Bailey's Industrial oil and fat products , 2005 .

[116]  S. Britz,et al.  Warm temperatures or drought during seed maturation increase free alpha-tocopherol in seeds of soybean (Glycine max [L.] Merr.). , 2002, Journal of agricultural and food chemistry.

[117]  I. Chung,et al.  Comparison of isoflavones composition in seed, embryo, cotyledon and seed coat of cooked-with-rice and vegetable soybean (Glycine max L.) varieties , 2007 .

[118]  D. Dornbos,et al.  Soybean seed protein and oil contents and fatty acid composition adjustments by drought and temperature , 1992 .

[119]  J. W. Tanner,et al.  Genotype x Environment Interactions, Stability, and Agronomic Performance of Soybean with Altered Fatty Acid Profiles. , 2002, Crop science.

[120]  M. Westgate,et al.  Rate and duration of seed component accumulation in water-stressed soybean. , 2010 .

[121]  Pengyin Chen,et al.  Sugar Variation in Soybean Seed Assessed with a Rapid Extraction and Quantification Method , 2009 .

[122]  Harald Martens,et al.  Evaluation of nonstarch polysaccharides and oligosaccharide content of different soybean varieties (Glycine max) by near-infrared spectroscopy and proteomics. , 2005, Journal of agricultural and food chemistry.

[123]  N. Leon,et al.  Effects of Genotype × Environment Interaction on Agronomic Traits in Soybean , 2010 .

[124]  G. Beecher,et al.  Isoflavones in retail and institutional soy foods. , 1999, Journal of agricultural and food chemistry.

[125]  R. Nelson,et al.  Effect of temperature and soil moisture status during seed development on soybean seed isoflavone concentration and composition , 2005 .

[126]  D. R. Panthee,et al.  Registration of Soybean Germplasm Lines TN03–350 and TN04–5321 with Improved Protein Concentration and Quality , 2006 .

[127]  B. Mikami,et al.  Crystal structure of soybean proglycinin A1aB1b homotrimer. , 2001, Journal of molecular biology.

[128]  T. Sakai,et al.  Soy isoflavones and immunity. , 2008, The journal of medical investigation : JMI.

[129]  S. Khanizadeh,et al.  Assessment of the protein quality of fourteen soybean [Glycine max (L.) Merr.] cultivars using amino acid analysis and two-dimensional electrophoresis , 2007 .

[130]  R. Nelson,et al.  Evaluation of the USDA Soybean Germplasm Collection: Maturity Groups 000 to IV (PI 273.483 to PI 427.107) , 1987 .

[131]  C. Weaver,et al.  Soy isoflavones and bone health: the relationship is still unclear. , 2005, The Journal of nutrition.

[132]  R. D. Seif,et al.  Components of Developing Soybean Seeds: Oil, Protein, Sugars, Starch, Organic Acids, and Amino Acids1 , 1977 .

[133]  B. Roe,et al.  The FAD2 Gene Family of Soybean: Insights into the Structural and Functional Divergence of a Paleopolyploid Genome , 2007 .

[134]  R. Shoemaker,et al.  Molecular Mapping of the Mutant fap4(A24) Allele for Elevated Palmitate Concentration in Soybean , 2013 .

[135]  K. Bilyeu,et al.  Composition, Vigor, and Proteome of Mature Soybean Seeds Developed under High Temperature , 2009 .

[136]  G. R. List,et al.  Potential margarine oils from genetically modified soybeans , 1996 .

[137]  Biochemical and Molecular Characterization of a Mutation That Confers a Decreased Raffinosaccharide and Phytic Acid Phenotype on Soybean Seeds , 2002, Plant Physiology.

[138]  Z. Sikorski,et al.  Chemical and Functional Properties of Food Lipids , 2002 .

[139]  I. Mateos-Aparicio,et al.  Chemical composition and dietary fibre of yellow and green commercial soybeans (Glycine max) , 2007 .

[140]  M. Ishimoto,et al.  Accumulation of β-Conglycinin in Soybean Cotyledon through the Formation of Disulfide Bonds between α′- and α-Subunits1[W][OA] , 2012, Plant Physiology.

[141]  R. Kleiman,et al.  Effect of temperature on soybean seed constituents: Oil, protein, moisture, fatty acids, amino acids and sugars , 1982 .

[142]  Tong Wang Minor Constituents and Phytochemicals of Soybeans , 2008 .

[143]  R. L. Obendorf,et al.  Accumulation of soluble carbohydrates during seed development and maturation of low-raffinose, low-stachyose soybean. , 2009 .

[144]  P. Murphy,et al.  Tocopherols of soybean seeds and soybean curd (tofu) , 1986 .

[145]  P. J. Maughan,et al.  Identification of quantitative trait loci controlling sucrose content in soybean (Glycine max) , 2000, Molecular Breeding.

[146]  A. Cardinal,et al.  Correlation between temperature and oleic acid seed content in three segregating soybean populations. , 2009 .

[147]  C. Parsons,et al.  Nutritional evaluation of soybean meals varying in oligosaccharide content. , 2000, Poultry science.

[148]  D. Bhatnagar,et al.  Relative changes in tocopherols, isoflavones, total phenolic content, and antioxidative activity in soybean seeds at different reproductive stages. , 2009, Journal of agricultural and food chemistry.

[149]  Tomohiko Mori,et al.  Characterization of texture and mechanical properties of heat-induced soy protein gels , 1991 .

[150]  A. Vincent,et al.  Soy isoflavones: are they useful in menopause? , 2000, Mayo Clinic proceedings.

[151]  B. Larkins,et al.  Cellular and Molecular Biology of Plant Seed Development , 1997, Advances in Cellular and Molecular Biology of Plants.

[152]  Pengyin Chen,et al.  Changes in chemical composition during soybean seed development , 2011 .

[153]  K. Setchell,et al.  Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones. , 1998, The American journal of clinical nutrition.

[154]  D. G. Stevenson,et al.  Structures and Functional Properties of Starch From Seeds of Three Soybean (Glycine max (L.) Merr.) Varieties , 2006 .

[155]  Sheila E. Murphy,et al.  Genotype × Environment Interaction and Stability for Isoflavone Content in Soybean , 2009 .

[156]  H. Yoshida,et al.  Regional distribution of tocopherols and fatty acids within soybean seeds , 1998 .

[157]  J. Pokorn,et al.  Plant Lipids and Oils , 2002 .

[158]  H. Nguyen,et al.  Association of a Four‐Basepair Insertion in the P34 Gene with the Low‐Allergen Trait in Soybean , 2009 .

[159]  M. Scarino,et al.  Evidence that polyunsaturated lecithin induces a reduction in plasma cholesterol level and favorable changes in lipoprotein composition in hypercholesterolemic rats. , 1990, Journal of NutriLife.

[160]  J. W. Burton,et al.  Registration of ‘Prolina’ Soybean , 1999 .

[161]  J. W. Burton,et al.  A simple and rapid procedure for phytate determination in soybeans and soy products , 2005 .

[162]  W. Fehr,et al.  Agronomic and Seed Traits of Soybean Lines Containing the High‐Oleate Transgene DP‐305423‐1 , 2013 .

[163]  L. Thompson,et al.  Phytic acid and minerals: effect on early markers of risk for mammary and colon carcinogenesis. , 1991, Carcinogenesis.

[164]  P. Murphy,et al.  Isoflavone composition of American and Japanese soybeans in Iowa: effects of variety, crop year, and location , 1994 .

[165]  Functional Foods and Biotechnology , 2019 .

[166]  W. Fehr,et al.  Agronomic and seed traits of soybean lines with high-oleate concentration , 2011 .

[167]  Keshun Liu,et al.  Soybeans: Chemistry, Technology and Utilization , 1997 .

[168]  T. Carter,et al.  Registration of N6202 Soybean Germplasm with High Protein, Favorable Yield Potential, Large Seed, and Diverse Pedigree , 2010 .

[169]  W. Fehr,et al.  Agronomic and Seed Characteristics of Soybean Lines with Increased Oleate Content , 2008 .

[170]  E. Piper,et al.  Temperature and cultivar effects on soybean seed oil and protein concentrations , 1999 .

[171]  P. Kerr,et al.  Gas production in human ingesting a soybean flour derived from beans naturally low in oligosaccharides. , 1999, The American journal of clinical nutrition.

[172]  S. Damodaran,et al.  Food Proteins and Their Applications , 1997 .

[173]  E. Schmelz Dietary sphingomyelin and other sphingolipids in health and disease. , 2000 .

[174]  W. Fehr,et al.  Phenotypic and Molecular Analysis of Oleate Content in the Mutant Soybean Line M23 , 2005 .

[175]  D. Hildebrand,et al.  Early-maturing soybean cropping system : III. Protein and oil contents and oil composition , 1997 .

[176]  I. Rose Effects of moisture stress on the oil and protein components of soybean seeds , 1988 .

[177]  H. Hauser,et al.  The structure, physical and chemical properties of the soy bean protein glycinin. , 1975, Biochimica et biophysica acta.

[178]  C. Grieshop,et al.  Amino acid, carbohydrate, and fat composition of soybean meals prepared at 55 commercial U.S. soybean processing plants. , 2005, Journal of agricultural and food chemistry.

[179]  V. Raboy,et al.  The timing and rate of phytic Acid accumulation in developing soybean seeds. , 1987, Plant physiology.

[180]  P. Utterback,et al.  Nutritional value of soybean meal produced from conventional, high-protein, or low-oligosaccharide varieties of soybeans and fed to broiler chicks. , 2011, Poultry science.

[181]  P. Murphy,et al.  Mass Balance Study of Isoflavones during Soybean Processing , 1996 .

[182]  H. Krishnan Engineering Soybean for Enhanced Sulfur Amino Acid Content , 2005 .

[183]  S. Oh,et al.  Effects of Raw, Cooked, and Germinated Small Black Soybean Powders on Dietary Fiber Content and Gastrointestinal Functions , 2006 .

[184]  G. Fahey,et al.  Extrusion conditions affect chemical composition and in vitro digestion of select food ingredients. , 2004, Journal of agricultural and food chemistry.

[185]  M. Westgate,et al.  Meta-analysis of environmental effects on soybean seed composition , 2009 .

[186]  Tsung Min Kuo,et al.  Content of raffinose oligosaccharides and sucrose in various plant seeds , 1988 .

[187]  M. Abbasi,et al.  Soybean Yield and Chemical Composition in Response to Phosphorus–Potassium Nutrition in Kashmir , 2012 .

[188]  J. W. Burton,et al.  Response of Low Seed Phytic Acid Soybeans to Increases in External Phosphorus Supply , 2007 .

[189]  D. Fukushima Recent Progress in Research and Technology on Soybeans , 2001 .

[190]  A. Kinney,et al.  Genetic Modification Removes an Immunodominant Allergen from Soybean1,212 , 2003, Plant Physiology.

[191]  R. E. Phillips,et al.  Effect of Moisture Stress on Seed Growth in Soybeans1 , 1984 .

[192]  M. Alpaslan,et al.  Seed composition of soybeans grown in the Harran region of Turkey as affected by row spacing and irrigation. , 2002, Journal of agricultural and food chemistry.

[193]  L. Gibson,et al.  Soybean seed composition under high day and night growth temperatures , 1996 .

[194]  P. V. Van Soest,et al.  The chemistry and estimation of fibre , 1973, Proceedings of the Nutrition Society.

[195]  G. O. Almonor,et al.  Temperature effects on tocopherol composition in soybeans with genetically improved oil quality , 1998 .

[196]  J. Dardanelli,et al.  Environmental Variation and Correlation of Seed Components in Nontransgenic Soybeans: Protein, Oil, Unsaturated Fatty Acids, Tocopherols, and Isoflavones , 2011 .

[197]  W. Fehr,et al.  Molecular Characterization of the Mutant fap3(A22) Allele for Reduced Palmitate Concentration in Soybean , 2011 .

[198]  Sandra Ferry,et al.  Inositol hexakisphosphate blocks tumor cell growth by activating apoptotic machinery as well as by inhibiting the Akt/NFkappaB-mediated cell survival pathway. , 2002, Carcinogenesis.

[199]  D. Kritchevsky,et al.  Phytosterols—health benefits and potential concerns: a review , 2005 .

[200]  A. Kikuchi,et al.  Low Isoflavone Content in Some Early Maturing Cultivars, So-called “Summer-type Soybeans” (Glycine max (L) MERRILL). , 1991 .

[201]  V. Pantalone,et al.  Genetic regulation of elevated stearic acid concentration in soybean oil , 2002 .

[202]  W. Fehr Breeding for Modified Fatty Acid Composition in Soybean , 2007 .