Solvent free synthesis of 3,4-dihydropyrimidine-2-(1H)-ones/thiones catalyzed by N,O-bis(trimethylsilyl)acetamide and dicyclohexyl carbodimide

[1]  H. Slimi,et al.  Synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones via Biginelli reaction promoted by bismuth(III)nitrate or PPh3 without solvent , 2016 .

[2]  R. Rodriguez.  Target‐Oriented and Diversity‐Oriented Organic Synthesis , 2012 .

[3]  T. Müller.  Multicomponent reactions , 2011, Beilstein journal of organic chemistry.

[4]  Xue‐Wei Liu,et al.  A microwave-assisted, copper-catalyzed three-component synthesis of dihydropyrimidinones under mild conditions , 2011 .

[5]  R. Borah,et al.  A new protocol for Biginelli (or like) reaction under solvent-free grinding method using Fe (NO3)3.9H2O as catalyst , 2010 .

[6]  S. Ji,et al.  Brønsted base-catalyzed one-pot three-component Biginelli-type reaction: an efficient synthesis of 4,5,6-triaryl-3,4-dihydropyrimidin-2(1H)-one and mechanistic study. , 2010, The Journal of organic chemistry.

[7]  K. Pandiarajan,et al.  Synthesis and in vitro microbiological evaluation of novel 4-aryl-5-isopropoxycarbonyl-6-methyl-3,4-dihydropyrimidinones. , 2010, European journal of medicinal chemistry.

[8]  H. Shaterian,et al.  Al(HSO4)3 and Al2O3-SO3H as Efficient Catalysts for Modified Preparation of 3,4-Dihydropyrimidin-2 (1H)-ones/thiones , 2009 .

[9]  Zhen Li,et al.  NaIO4-catalyzed one-pot synthesis of dihydropyrimidinones at room temperature under solvent-free conditions , 2009 .

[10]  Habibullah,et al.  An improved synthesis of Biginelli-type compounds via phase-transfer catalysis , 2009 .

[11]  Xi‐Cun Wang,et al.  General and Green Synthesis of C-6 Sulfonylmethyl 4-Aryl-3,4-dihydropyrimidinones in Water , 2009 .

[12]  K. Bahrami,et al.  Highly Efficient Solvent-Free Synthesis of Dihydropyrimidinones Catalyzed by Zinc Oxide , 2009 .

[13]  V. Dotsenko,et al.  A chemical placebo: NaCl as an effective, cheapest, non-acidic and greener catalyst for Biginelli-type 3,4-dihydropyrimidin-2(1H)-ones (-thiones) synthesis , 2009, Molecular Diversity.

[14]  B. Carboni,et al.  A one-pot Biginelli synthesis of 3,4-dihydropyrimidin-2-(1H)-ones/thiones catalyzed by triphenylphosphine as Lewis base , 2008 .

[15]  C. Ramalingan,et al.  Tetrachlorosilane catalyzed multicomponent one-step fusion of biopertinent pyrimidine heterocycles , 2008 .

[16]  Ş. Beşoluk,et al.  Solvent-free synthesis of dihydropyrimidinones catalyzed by alumina sulfuric acid at room temperature , 2008 .

[17]  K. Saidi,et al.  Microwave-assisted synthesis of dihydropyrimidin-2(1H)-ones using graphite supported lanthanum chloride as a mild and efficient catalyst. , 2008, Bioorganic & medicinal chemistry letters.

[18]  B. Thiede,et al.  New chemical tools for investigating human mitotic kinesin Eg5. , 2007, Bioorganic & medicinal chemistry.

[19]  Atul Kumar,et al.  An efficient bakers' yeast catalyzed synthesis of 3,4-dihydropyrimidin-2-(1H)-ones , 2007 .

[20]  Yang Yu,et al.  One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using chloroacetic acid as catalyst. , 2007, Bioorganic & medicinal chemistry letters.

[21]  K. Erol,et al.  Synthesis of 4-aryl-3,4-dihydropyrimidin-2(1H)-thione derivatives as potential calcium channel blockers. , 2006, Bioorganic & medicinal chemistry.

[22]  Ying Sun,et al.  Identification and characterization of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones as inhibitors of the fatty acid transporter FATP4. , 2006, Bioorganic & medicinal chemistry letters.

[23]  Hui Xu,et al.  Brønsted Acidic Ionic Liquid: An Efficient and Reusable Catalyst for the Synthesis of 3,4‐Dihydropyrimidin‐2(1H)‐ones , 2006 .

[24]  E. Rafiee,et al.  A practical and green approach towards synthesis of dihydropyrimidinones: using heteropoly acids as efficient catalysts. , 2006, Bioorganic & medicinal chemistry letters.

[25]  T. Tolstikova,et al.  Antiarrhythmic activity of 4,6-di(het)aryl-5-nitro-3,4-dihydropyrimidin-(1H)-2-ones and its effects on arterial pressure in rats. , 2006, Bioorganic & medicinal chemistry letters.

[26]  Alexander Dömling,et al.  Recent developments in isocyanide based multicomponent reactions in applied chemistry. , 2006, Chemical reviews.

[27]  R. Gibbs,et al.  Scandium(III) Triflate as an Efficient and Reusable Catalyst for Synthesis of 3,4‐Dihydropyrimidin‐2(1H)‐ones , 2005 .

[28]  W. Su,et al.  One-pot synthesis of dihydropyrimidiones catalyzed by strontium(II) triflate under solvent-free conditions , 2005 .

[29]  D. Shinde,et al.  One-pot construction of dihydropyrimidinones in ionic liquids , 2004 .

[30]  B. S. Holla,et al.  One pot synthesis of thiazolodihydropyrimidinones and evaluation of their anticancer activity. , 2004, European journal of medicinal chemistry.

[31]  Shenlin Huang,et al.  Trimethylsilyl Chloride: A Facile and Efficient Reagent for One‐Pot Synthesis of 3,4‐Dihydropyrimidin‐2(1H)‐ones , 2004 .

[32]  A. Sudalai,et al.  Cu(OTf)2: a reusable catalyst for high-yield synthesis of 3,4-dihydropyrimidin-2(1H)-ones , 2003 .

[33]  H. Mereyala,et al.  Green chemistry approaches to the synthesis of 5-alkoxycarbonyl-4-aryl-3,4- dihydropyrimidin-2(1H)-ones by a three-component coupling of one-pot condensation reaction: comparison of ethanol, water, and solvent-free conditions. , 2003, The Journal of organic chemistry.

[34]  B. Ranu,et al.  A practical and green approach towards synthesis of dihydropyrimidinones without any solvent or catalyst , 2002 .

[35]  M. Kidwai,et al.  A novel one pot synthesis of nitrogen containing heterocycles: an alternate methodology to the Biginelli and Hantzsch reactionsElectronic supplementary information (ESI) available: General procedure for the synthesis of Biginelli tetrahydropyrimidines (2b???e) and 1,4-dihydropyridines 3a???e. See ht , 2002 .

[36]  C. S. Reddy,et al.  ChemInform Abstract: Mn(OAc)3×2H2O-Mediated Three-Component, One-Pot Condensation Reaction: An Efficient Synthesis of 4-Aryl-Substituted 3,4-Dihydropyrimidin-2-ones. , 2001 .

[37]  Jiajian Peng,et al.  Ionic liquids catalyzed Biginelli reaction under solvent-free conditions , 2001 .

[38]  C. Kappe,et al.  Solid-Phase Synthesis of Dihydropyrimidones via N-Acyliminium Ion-Based α-Ureidoalkylations , 2001 .

[39]  J. Yadav,et al.  Ultrasound-accelerated synthesis of 3,4-dihydropyrimidin-2(1H)-ones with ceric ammonium nitrate , 2001 .

[40]  C. Kappe.  Biologically active dihydropyrimidones of the Biginelli-type--a literature survey. , 2000, European journal of medicinal chemistry.

[41]  C. Kappe.  Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog. , 2000, Accounts of chemical research.

[42]  B. Ranu,et al.  Indium(III) chloride-catalyzed one-pot synthesis of dihydropyrimidinones by a three-component coupling of 1,3-dicarbonyl compounds, aldehydes, and urea: an improved procedure for the Biginelli reaction. , 2000, The Journal of organic chemistry.

[43]  C. Qian,et al.  Lanthanide triflate catalyzed Biginelli reaction. one-pot synthesis of dihydropyrimidinones under solvent-free conditions. , 2000, The Journal of organic chemistry.

[44]  A. Shutalev,et al.  Synthesis of 4-alkyl-substituted 1,2,3,4-tetrahydropyrimidin-2-ones by the Biginelli reaction , 1998 .

[45]  A. Dömling.  Isocyanide Based Multi Component Reactions in Combinatorial Chemistry , 2010 .

[46]  C. Kappe.  4-Aryldihydropyrimidines via the Biginelli Condensation: Aza-Analogs of Nifedipine-Type Calcium Channel Modulators , 1998 .

[47]  J. Ellman,et al.  Combinatorial chemistry and new drugs. , 1997, Scientific American.

[48]  Rongan Zhang,et al.  Calcium entry blockers and activators: conformational and structural determinants of dihydropyrimidine calcium channel modulators. , 1995, Journal of medicinal chemistry.

[49]  I. Ugi,et al.  Multicomponent reactions in organic chemistry , 1994 .

[50]  C. Kappe.  100 years of the biginelli dihydropyrimidine synthesis , 1993 .

[51]  S. Moreland,et al.  Dihydropyrimidine calcium channel blockers. 4. Basic 3-substituted-4-aryl-1,4-dihydropyrimidine-5-carboxylic acid esters. Potent antihypertensive agents. , 1992, Journal of medicinal chemistry.

[52]  A Hedberg,et al.  Dihydropyrimidine calcium channel blockers. 3. 3-Carbamoyl-4-aryl-1,2,3,4-tetrahydro-6-methyl-5-pyrimidinecarboxylic acid esters as orally effective antihypertensive agents. , 1991, Journal of medicinal chemistry.

[53]  V. P. Mamaev,et al.  Pyrimidines: XXI. 5-substituted 2-hydroxy-4,6-diphenylpyrimidines , 1970 .

[54]  H. Harwood,et al.  RESEARCHES ON PYRIMIDINES. CXXX. SYNTHESIS OF 2-KETO-1,2,3,4-TETRAHYDROPYRIMIDINES , 1932 .