Mixed-metal polymetallic platinum complexes designed to interact with DNA

[1]  C. Moucheron,et al.  Photophysics of Ru(phen)2(PHEHAT)2+: A Novel “Light Switch” for DNA and Photo-oxidant for Mononucleotides , 1997 .

[2]  M R Arkin,et al.  Rates of DNA-Mediated Electron Transfer Between Metallointercalators , 1996, Science.

[3]  K. Brewer,et al.  Spectroscopic and Electrochemical Properties of a Series of Mixed-Metal d6,d8 Bimetallic Complexes of the Form [(bpy)2M(BL)PtCl2]2+ (bpy = 2,2‘-Bipyridine; BL = dpq (2,3-Bis(2- pyridyl)quinoxaline) or dpb (2,3-Bis(2-pyridyl)- benzoquinoxaline); M = OsII or RuII) , 1996 .

[4]  Huifang Huang,et al.  Solution Structure of a Cisplatin-Induced DNA Interstrand Cross-Link , 1995, Science.

[5]  R. Perez,et al.  Cytotoxicity, cellular accumulation and DNA binding of oxaliplatin isomers. , 1995, Cancer letters.

[6]  S. Lippard,et al.  Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin , 1995, Nature.

[7]  N. Turro,et al.  Proton Transfer Quenching of the MLCT Excited State of Ru(phen)2dppz2+ in Homogeneous Solution and Bound to DNA , 1995 .

[8]  D. McMillin,et al.  DNA-Binding Studies of a Bifunctional Platinum Complex That Is a Luminescent Intercalator , 1995 .

[9]  R. Baan,et al.  Formation of DNA adducts by the anticancer drug carboplatin: different nucleotide sequence preferences in vitro and in cells. , 1995, Biochemistry.

[10]  J. Barton,et al.  Os(phen)2(dppz)2+: A Red-Emitting DNA Probe , 1995 .

[11]  L. Marzilli,et al.  DNA Adduct Formation by Platinum Anticancer Drugs. Insight into an Unusual GpG Intrastrand Cross-Link in a Hairpin-like DNA Oligonucleotide Using NMR and Distance Geometry Methods , 1994 .

[12]  B. Van Houten,et al.  Sequence specificity of DNA-DNA interstrand cross-link formation by cisplatin and dinuclear platinum complexes. , 1994, Biochemistry.

[13]  H. Homesley,et al.  Cancers of the uterine cervix and endometrium: major issues and future research directions. , 1994, Seminars in oncology.

[14]  A. Khokhar,et al.  Circumvention of platinum resistance: structure-activity relationship for homologous series of ammine/amine platinum(II) complexes in L1210 cell lines. , 1994, Anti-cancer drug design.

[15]  B. Van Houten,et al.  Ligand effects on platinum binding to DNA. A comparison of DNA binding properties for cis- and trans-[PtCl2(amine)2] (amine = NH3, pyridine). , 1993, Biochemistry.

[16]  R. Sheardy,et al.  A new class of DNA metallobinders showing spectator ligand size selectivity: binding of ligand-bridged bimetallic complexes of ruthenium(II) to calf thymus DNA , 1993 .

[17]  G. Zon,et al.  DNA hairpin formation in adducts with platinum anticancer drugs: gel electrophoresis provides new information and a caveat , 1993 .

[18]  Y. Fujiwara,et al.  A new anticancer platinum compound, (-)-(R)-2-aminomethyl-pyrrolidine(1,1-cyclobutanedicarboxylato) platinum(II): DNA interstrand crosslinking, repair and lethal effects in normal human, Fanconi's anaemia and xeroderma pigmentosum cells. , 1993, British Journal of Cancer.

[19]  N. Turro,et al.  Characterization of dipyridophenazine complexes of ruthenium(II): the light switch effect as a function of nucleic acid sequence and conformation. , 1992, Biochemistry.

[20]  P. O'Connor,et al.  Increased gene-specific repair of cisplatin interstrand cross-links in cisplatin-resistant human ovarian cancer cell lines , 1992, Molecular and cellular biology.

[21]  J. Barton,et al.  Novel dipyridophenazine complexes of ruthenium(II): exploring luminescent reporters of DNA , 1992 .

[22]  L. Orgel,et al.  An efficient, sequence-specific method for crosslinking complementary oligonucleotides using binuclear platinum complexes. , 1991, Nucleic acids research.

[23]  B. Van Houten,et al.  Comparison of chemical reactivity, cytotoxicity, interstrand cross-linking and DNA sequence specificity of bis(platinum) complexes containing monodentate or bidentate coordination spheres with their monomeric analogues. , 1990, Biochemistry.

[24]  Christopher A. Lepre,et al.  Platinum-195 NMR kinetic and mechanistic studies of cis- and trans-diamminedichloroplatinum(II) binding to DNA , 1990 .

[25]  John D. Roberts,et al.  Interaction of novel bis(platinum) complexes with DNA. , 1989, Nucleic acids research.

[26]  J. Barton,et al.  Metal-activated hydrolytic cleavage of DNA , 1987 .

[27]  S. Lippard,et al.  Structural aspects of platinum anticancer drug interactions with DNA , 1987 .

[28]  P. Lohman,et al.  Adducts of the antitumor drug cis-diamminedichloroplatinum(II) with DNA: formation, identification, and quantitation. , 1985, Biochemistry.

[29]  P. Lohman,et al.  Induction and repair of DNA cross-links in chinese hamster ovary cells treated with various platinum coordination compounds in relation to platinum binding to DNA, cytotoxicity, mutagenicity, and antitumor activity. , 1984, Cancer research.

[30]  J. Sambrook,et al.  Molecular Cloning: A Laboratory Manual , 2001 .

[31]  F. Friedlos,et al.  The frequency of interstrand cross-links in DNA following reaction of cis-diamminedichloroplatinum(II) with cells in culture or DNA in vitro: stability of DNA cross-links and their repair. , 1982, Chemico-biological interactions.