Reader's guide to critical appraisal of cohort studies: 1. Role and design

Cohort studies can provide valuable information unavailable from randomised trials, but readers need to be alert to possible flaws

[1]  L. Hirsch.  Competing interests: none declared. , 2006 .

[2]  C. Callahan,et al.  Improving Medication Use for Older Adults: An Integrated Research Agenda , 2003, Annals of Internal Medicine.

[3]  A. Laupacis,et al.  Observational study of upper gastrointestinal haemorrhage in elderly patients given selective cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs , 2002, BMJ : British Medical Journal.

[4]  R. Wood,et al.  Effect of highly active antiretroviral therapy on incidence of tuberculosis in South Africa: a cohort study , 2002, The Lancet.

[5]  K. Schulz,et al.  Bias and causal associations in observational research , 2002, The Lancet.

[6]  J. Fellay,et al.  For Personal Use. Only Reproduce with Permission from the Lancet Publishing Group , 2022 .

[7]  D. Moher,et al.  The Revised CONSORT Statement for Reporting Randomized Trials: Explanation and Elaboration , 2001, Annals of Internal Medicine.

[8]  H. Morgenstern,et al.  Confounding in health research. , 2001, Annual review of public health.

[9]  A. Hartz,et al.  A comparison of observational studies and randomized, controlled trials. , 2000, The New England journal of medicine.

[10]  C Bain,et al.  Interpreting the evidence: choosing between randomised and non-randomised studies , 1999, BMJ.

[11]  B. Psaty,et al.  Assessment and Control for Confounding by Indication in Observational Studies , 1999, Journal of the American Geriatrics Society.

[12]  Douglas G Altman,et al.  Treatment allocation in controlled trials: why randomise? , 1999, BMJ.

[13]  N. Black.  Why we need observational studies to evaluate the effectiveness of health care , 1996, BMJ.

[14]  J. Avorn,et al.  The exclusion of the elderly and women from clinical trials in acute myocardial infarction. , 1992, JAMA.