Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target
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S. Horvath | D. Geschwind | S. Nelson | T. Cloughesy | L. Liau | P. Mischel | H. Wu | R. Felciano | M. Carlson | H. Kornblum | B. Zhang | Hong Wu | A. Scheck | Yohan Lee | P. Febbo | M. Carlson | K. Lu | S. Zhu | M. Laurance | W. Zhao | S. Qi | Z. Chen | Y. Lee | Shaojun Zhu | B. Zhang | S. Nelson | Bin Zhang | Zugen Chen | B. Zhang | B. Zhang | W. Zhao | W. Zhao
[1] Eytan Domany,et al. Identification of a proliferation gene cluster associated with HPV E6/E7 expression level and viral DNA load in invasive cervical carcinoma , 2005, Oncogene.
[2] Alfredo Quiñones-Hinojosa,et al. Techniques to assess the proliferative potential of brain tumors , 2005, Journal of Neuro-Oncology.
[3] Yudong D. He,et al. Gene expression profiling predicts clinical outcome of breast cancer , 2002, Nature.
[4] John D. Storey,et al. A network-based analysis of systemic inflammation in humans , 2005, Nature.
[5] M. Daly,et al. PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes , 2003, Nature Genetics.
[6] D. Botstein,et al. Singular value decomposition for genome-wide expression data processing and modeling. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[7] C. Walsh,et al. Protein-truncating mutations in ASPM cause variable reduction in brain size. , 2003, American journal of human genetics.
[8] Alexander F. Markham,et al. ASPM is a major determinant of cerebral cortical size , 2002, Nature Genetics.
[9] P. Brown,et al. Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[10] T. Golub,et al. Genomic approaches to hematologic malignancies. , 2004, Blood.
[11] M. Berger,et al. Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.
[12] Ugo Orfanelli,et al. Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma , 2004, Cancer Research.
[13] T. Golub,et al. A Mechanism of Cyclin D1 Action Encoded in the Patterns of Gene Expression in Human Cancer , 2003, Cell.
[14] A. Larsen,et al. DNA topoisomerase I in oncology: Dr Jekyll or Mr Hyde? , 1999, Pathology & Oncology Research.
[15] S. Horvath,et al. Gene Expression Profiling of Gliomas Strongly Predicts Survival , 2004, Cancer Research.
[16] Koji Yoshimoto,et al. Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. , 2005, The New England journal of medicine.
[17] A. Barabasi,et al. Lethality and centrality in protein networks , 2001, Nature.
[18] Daniel H. Geschwind,et al. Cancerous stem cells can arise from pediatric brain tumors , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[19] Yibin Kang. Functional genomic analysis of cancer metastasis: biologic insights and clinical implications , 2005, Expert review of molecular diagnostics.
[20] C. Woods,et al. Autosomal recessive primary microcephaly (MCPH): a review of clinical, molecular, and evolutionary findings. , 2005, American journal of human genetics.
[21] M. J. van de Vijver,et al. Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis. , 2006, Journal of the National Cancer Institute.
[22] Cynthia Hawkins,et al. Identification of a cancer stem cell in human brain tumors. , 2003, Cancer research.
[23] Vladimir Larionov,et al. The microcephaly ASPM gene is expressed in proliferating tissues and encodes for a mitotic spindle protein. , 2005, Human molecular genetics.
[24] Wieland B Huttner,et al. Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells , 2006, Proceedings of the National Academy of Sciences.
[25] Edison T Liu,et al. Microarrays and clinical investigations. , 2004, The New England journal of medicine.
[26] C. Ponting,et al. Evolution of primary microcephaly genes and the enlargement of primate brains. , 2005, Current opinion in genetics & development.
[27] C. James,et al. PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme. , 2001, Journal of the National Cancer Institute.
[28] S. Horvath,et al. Gene connectivity, function, and sequence conservation: predictions from modular yeast co-expression networks , 2006, BMC Genomics.
[29] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[30] A. Barabasi,et al. Network biology: understanding the cell's functional organization , 2004, Nature Reviews Genetics.
[31] Lan V. Zhang,et al. Evidence for dynamically organized modularity in the yeast protein–protein interaction network , 2004, Nature.
[32] R. Henkelman,et al. Identification of human brain tumour initiating cells , 2004, Nature.
[33] D. Koller,et al. A module map showing conditional activity of expression modules in cancer , 2004, Nature Genetics.
[34] Vladimir Larionov,et al. Accelerated Evolution of the ASPM Gene Controlling Brain Size Begins Prior to Human Brain Expansion , 2004, PLoS biology.
[35] D. Altieri. Survivin, versatile modulation of cell division and apoptosis in cancer , 2003, Oncogene.
[36] Patrick D. Evans,et al. Ongoing Adaptive Evolution of ASPM, a Brain Size Determinant in Homo sapiens , 2005, Science.
[37] Jeffrey T. Chang,et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies , 2006, Nature.
[38] Hyo Jin Kang,et al. BRCA1 Regulates Gene Expression for Orderly Mitotic Progression , 2005, Cell cycle.
[39] T. Hamid,et al. Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells , 2005, Molecular Cancer.
[40] Albert,et al. Emergence of scaling in random networks , 1999, Science.
[41] M. Loda,et al. The EZH2 polycomb transcriptional repressor--a marker or mover of metastatic prostate cancer? , 2002, Cancer cell.
[42] Paul S Mischel,et al. Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo. , 2003, Cancer research.
[43] Michael E Phelps,et al. Systems Biology and New Technologies Enable Predictive and Preventative Medicine , 2004, Science.
[44] P. D. Andrews,et al. Aurora kinases: shining lights on the therapeutic horizon? , 2005, Oncogene.