Orbital exenteration for secondary orbital tumors: a series of seven cases.

BACKGROUND Exenteration is indicated in patients with malignant neoplasms of orbital contents. It entails the removal of the eyeball together with its extraocular muscles and other soft tissues. Exenterations can be classified into (1) total, (2) subtotal, and (3) supertotal exenteration. Retrospectively study, we reviewed 7 patients that had received exenteration/subtotal exenteration with spontaneous granulation/myocutaneous flap implantation or eyelid-sparing exenteration with myocutaneous flap. Primary lesions, histopathological examination results, treatments, and recurrences are discussed. METHODS A retrospective study of the years 1987 through 2000 disclosed 7 patients that underwent exenteration/subtotal exenteration. The patients ranged in age from 41 to 68 years. Two patients underwent total exenteration without socket augmentation; 4 patients underwent exenteration/ subtotal exenteration with immediate facial reconstruction, and 1 with delayed facial reconstruction. RESULTS Classification of the 7 patients showed that 2 had basal cell carcinoma of the skin, 2 had squamous cell carcinoma of the conjunctiva, 1 had squamous cell carcinoma of the paranasal sinus, 1 had rhabdomyosarcoma of the paranasal sinus, and 1 had intracranial meningioma. Radiotherapy was performed in 6 of the patients and chemotherapy in 2. Central nerve system invasion was noted in 2 patients, and 1 died due to it. CONCLUSION Secondary orbital tumors involved the orbit from adjacent tissues: paranasal sinuses, nasopharynx, lacrimal sac, conjunctiva, eyelid, intraocular tissue, and intracranial tissues. Combined surgeries are necessary for complete tumor removal. And the imaging studies should include the field of the orbit, sinus, and brain to search for the primary lesions.

[1]  D. Albert,et al.  Principles and practice of ophthalmology , 1999 .

[2]  G. Ellis,et al.  Rhabdomyosarcoma presumed metastatic to the orbit. , 1996, Ophthalmology.

[3]  C. Shields Basal Cell Carcinoma of the Eyelids , 1993, International ophthalmology clinics.

[4]  J. Dutton,et al.  A 20-year series of orbital exenteration. , 1991, American journal of ophthalmology.

[5]  C. Shields,et al.  Orbital exenteration with eyelid sparing: indications, technique, and results. , 1991, Ophthalmic surgery.

[6]  J. Maroon,et al.  The management of optic nerve sheath meningiomas. , 1988, American journal of ophthalmology.

[7]  A. Sadove,et al.  Embryonal rhabdomyosarcoma arising in the masseter muscle as a second malignant neoplasm. , 1988, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[8]  John A. Mccrary Irradiation of meningiomas of the intracranial anterior visual pathway , 1987 .

[9]  A. Hornblass,et al.  Surgical management of squamous cell carcinoma of the lid. , 1986, Ophthalmic plastic and reconstructive surgery.

[10]  A. Putterman Orbital exenteration with spontaneous granulation. , 1986, Archives of ophthalmology.

[11]  G. A. Thompson,et al.  Basal and squamous cell carcinoma of the eyelids and their treatment by radiotherapy. , 1984, International journal of radiation oncology, biology, physics.

[12]  R. Kennedy Indications and surgical techniques for orbital exenteration. , 1979, Ophthalmology.

[13]  J. Maroon,et al.  Microsurgical removal of a primary intraorbital meningioma. , 1978, American journal of ophthalmology.

[14]  F. Jakobiec,et al.  Ocular and Adnexal Tumors , 1973 .

[15]  C. Beard Observations on the treatment of basal cell carcinoma of the eyelids. The Wendell L. Huges Lecture. , 1975, Transactions. Section on Ophthalmology. American Academy of Ophthalmology and Otolaryngology.

[16]  E. Boldrey,et al.  Radiation therapy of meningiomas. , 1975, The American journal of roentgenology, radium therapy, and nuclear medicine.

[17]  F. Blodi,et al.  Reappraisal of basal cell carcinoma of the eyelids. , 1970, American journal of ophthalmology.

[18]  R. Butner,et al.  Basal cell carcinoma of the eyelids. A long-term follow-up study. , 1969, Archives of ophthalmology.

[19]  A. Domonkos TREATMENT OF EYELID CARCINOMA. , 1965, Archives of dermatology.

[20]  J. Shulman Treatment of malignant tumours of the eyelids by plastic surgery. , 1962, British journal of plastic surgery.

[21]  A. B. Reese,et al.  Exenteration of the orbit and repair by transplantation of the temporalis muscle. , 1961, American journal of ophthalmology.

[22]  H. Naquin Exenteration of the orbit. , 1954, A.M.A. archives of ophthalmology.

[23]  E F TRAUB,et al.  Cancer of skin. , 1954, Bulletin. New York Medical College.