Self-reconfigurable micro-implants for cross-tissue wireless and batteryless connectivity

We present the design, implementation, and evaluation of μmedIC, a fully-integrated wireless and batteryless micro-implanted sensor. The sensor powers up by harvesting energy from RF signals and communicates at near-zero power via backscatter. In contrast to prior designs which cannot operate across various in-body environments, our sensor can self-reconfigure to adapt to different tissues and channel conditions. This adaptation is made possible by two key innovations: a reprogrammable antenna that can tune its energy harvesting resonance to surrounding tissues, and a backscatter rate adaptation protocol that closes the feedback loop by tracking circuit-level sensor hints. We built our design on millimeter-sized integrated chips and flexible antenna substrates, and tested it in environments that span both in-vitro (fluids) and ex-vivo (tissues) conditions. Our evaluation demonstrates μmedIC's ability to tune its energy harvesting resonance by more than 200 MHz (i.e., adapt to different tissues) and to scale its bitrate by an order of magnitude up to 6Mbps, allowing it to support higher data rate applications (such as streaming low-res images) without sacrificing availability. This rate adaptation also allows μmedIC to scale its energy consumption by an order of magnitude down to 350 nanoWatts. These capabilities pave way for a new generation of networked micro-implants that can adapt to complex and time-varying in-body environments.

[1]  Sachin Katti,et al.  HitchHike: Practical Backscatter Using Commodity WiFi , 2016, SenSys.

[2]  Xinyu Zhang,et al.  Gyro in the air: tracking 3D orientation of batteryless internet-of-things , 2016, MobiCom.

[3]  John L. Volakis,et al.  A Radiating Near-Field Patch Rectenna for Wireless Power Transfer to Medical Implants at 2.4 GHz , 2018, IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology.

[4]  R. Bansal,et al.  Antenna theory; analysis and design , 1984, Proceedings of the IEEE.

[5]  Omid Salehi-Abari,et al.  In-body backscatter communication and localization , 2018, SIGCOMM.

[6]  A. K. Skrivervik,et al.  Design, Realization and Measurements of a Miniature Antenna for Implantable Wireless Communication Systems , 2011, IEEE Transactions on Antennas and Propagation.

[7]  R. W. Lau,et al.  The dielectric properties of biological tissues: III. Parametric models for the dielectric spectrum of tissues. , 1996, Physics in medicine and biology.

[8]  Y. Rahmat-Samii,et al.  Implanted antennas inside a human body: simulations, designs, and characterizations , 2004, IEEE Transactions on Microwave Theory and Techniques.

[9]  Amin Arbabian,et al.  A mm-Sized Implantable Medical Device (IMD) With Ultrasonic Power Transfer and a Hybrid Bi-Directional Data Link , 2015, IEEE Journal of Solid-State Circuits.

[10]  Gaetano Marrocco,et al.  Numerical and Experimental Characterization of Through-the-Body UHF-RFID Links for Passive Tags Implanted Into Human Limbs , 2014, IEEE Transactions on Antennas and Propagation.

[11]  Miao He,et al.  Design of a High-Efficiency 2.45-GHz Rectenna for Low-Input-Power Energy Harvesting , 2012, IEEE Antennas and Wireless Propagation Letters.

[12]  K. Philips,et al.  A self-calibrating RF energy harvester generating 1V at −26.3 dBm , 2013, 2013 Symposium on VLSI Circuits.

[13]  Deepak Ganesan,et al.  BLINK: a high throughput link layer for backscatter communication , 2012, MobiSys '12.

[14]  Elad Alon,et al.  Wireless Recording in the Peripheral Nervous System with Ultrasonic Neural Dust , 2016, Neuron.

[15]  R Bashirullah,et al.  Wireless Implants , 2010, IEEE Microwave Magazine.

[16]  Joshua R. Smith,et al.  Inter-Technology Backscatter: Towards Internet Connectivity for Implanted Devices , 2016, SIGCOMM.

[17]  Mohammad Rostami,et al.  Enabling Practical Backscatter Communication for On-body Sensors , 2016, SIGCOMM.

[18]  Fadel Adib,et al.  Enabling deep-tissue networking for miniature medical devices , 2018, SIGCOMM.

[19]  Jian Kang,et al.  Design and Optimization of Area-Constrained Wirelessly Powered CMOS UWB SoC for Localization Applications , 2016, IEEE Transactions on Microwave Theory and Techniques.

[20]  Vincent Liu,et al.  Enabling instantaneous feedback with full-duplex backscatter , 2014, MobiCom.

[21]  Kai Chang,et al.  Dual-frequency electronically tunable CPW-fed CPS dipole antenna , 1998 .

[22]  M. R. Yuce,et al.  Easy-to-Swallow Wireless Telemetry , 2012, IEEE Microwave Magazine.

[23]  Raj Mittra,et al.  Single-Layer Dual-/Tri-Band Inverted-F Antennas for Conformal Capsule Type of Applications , 2017, IEEE Transactions on Antennas and Propagation.

[24]  R. Kaul,et al.  Microwave engineering , 1989, IEEE Potentials.

[25]  Jian Kang,et al.  21.6 A 1.2cm2 2.4GHz self-oscillating rectifier-antenna achieving −34.5dBm sensitivity for wirelessly powered sensors , 2016, 2016 IEEE International Solid-State Circuits Conference (ISSCC).

[26]  Si Chen,et al.  MobiRate: Mobility-Aware Rate Adaptation Using PHY Information for Backscatter Networks , 2018, IEEE INFOCOM 2018 - IEEE Conference on Computer Communications.

[27]  Zhihua Wang,et al.  A Wireless Capsule Endoscope System With Low-Power Controlling and Processing ASIC , 2009, IEEE Transactions on Biomedical Circuits and Systems.

[28]  J. Vardaxoglou,et al.  Frequency and beam reconfigurable antenna using photoconducting switches , 2006, IEEE Transactions on Antennas and Propagation.

[29]  Anatoly Yakovlev,et al.  A 11μW Sub-pJ/bit reconfigurable transceiver for mm-sized wireless implants , 2013, Proceedings of the IEEE 2013 Custom Integrated Circuits Conference.

[30]  K. L. Montgomery,et al.  Wirelessly powered, fully internal optogenetics for brain, spinal and peripheral circuits in mice , 2015, Nature Methods.

[31]  Minkyu Je,et al.  High-Efficiency Wireless Power Transfer for Biomedical Implants by Optimal Resonant Load Transformation , 2013, IEEE Transactions on Circuits and Systems I: Regular Papers.

[32]  A. V. Vorst,et al.  Applications of RF/microwaves in medicine , 2002 .

[33]  Yuji Tanabe,et al.  Wireless power transfer to deep-tissue microimplants , 2014, Proceedings of the National Academy of Sciences.

[34]  Hang Wong,et al.  Multi-Polarization Reconfigurable Antenna for Wireless Biomedical System , 2017, IEEE Transactions on Biomedical Circuits and Systems.

[35]  Kevin Fu,et al.  They can hear your heartbeats: non-invasive security for implantable medical devices , 2011, SIGCOMM.

[36]  Young-Sik Seo,et al.  Wireless power transfer for a miniature gastrostimulator , 2012, 2012 42nd European Microwave Conference.

[37]  Moe Z. Win,et al.  Ultrawide Bandwidth RFID: The Next Generation? , 2010, Proceedings of the IEEE.

[38]  Ronan Sauleau,et al.  Impact of Tissue Electromagnetic Properties on Radiation Performance of In-Body Antennas , 2018, IEEE Antennas and Wireless Propagation Letters.

[39]  T. Meng,et al.  Optimal Frequency for Wireless Power Transmission Into Dispersive Tissue , 2010, IEEE Transactions on Antennas and Propagation.

[40]  Shahriar Mirabbasi,et al.  Design and Optimization of Resonance-Based Efficient Wireless Power Delivery Systems for Biomedical Implants , 2011, IEEE Transactions on Biomedical Circuits and Systems.

[41]  Canan Dagdeviren,et al.  The future of bionic dynamos , 2016, Science.

[42]  Jian Kang,et al.  A 960pW Co-Integrated-Antenna Wireless Energy Harvester for WiFi Backchannel Wireless Powering , 2018, 2018 IEEE International Solid - State Circuits Conference - (ISSCC).

[43]  Saeed Mohammadi,et al.  A CMOS integrated rectenna for implantable applications , 2016, 2016 IEEE MTT-S International Microwave Symposium (IMS).

[44]  Fadel Adib,et al.  Underwater backscatter networking , 2019, SIGCOMM.

[45]  A. K. Skrivervik Implantable antennas: The challenge of efficiency , 2013, 2013 7th European Conference on Antennas and Propagation (EuCAP).

[46]  David Wetherall,et al.  Ambient backscatter: wireless communication out of thin air , 2013, SIGCOMM.

[47]  Joshua R. Smith,et al.  Towards Battery-Free HD Video Streaming , 2018, NSDI.

[48]  C. Pyo,et al.  Design of RFID tag antennas using an inductively coupled feed , 2005 .

[49]  Shaoqiu Xiao,et al.  Design and Safety Considerations of an Implantable Rectenna for Far-Field Wireless Power Transfer , 2014, IEEE Transactions on Antennas and Propagation.