Correlation of transrectal ultrasonographic findings with histo pathology in prostatic cancer

Objective: To estimate the incidence of hyperechoic, hypoechoic, isoechoic, prostatic cancer in TRUS (transrectal ultrasound guided) guided prostatic specimens. Materials and Methods: Four hundred and ninety three patients with raised serum prostatic specific antigen (PSA) and abnormal DRE findings were subjected to TRUS-Guided prostate biopsy. Lateralized sextant biopsy plus prostatic cores from suspicious areas were obtained. Results: Out of 493 patients who were enrolled in the study, 65 (13.18) patients showed hyperechoic lesions on TRUS and 211 (42.79) patients had hypoechoic lesions on TRUS. Conclusion: Our study has revealed that hyperechoic lesions on transrectal ultrasonography have more chances of prostatic cancer as reported in previous literature, so we suggest that we should take additional biopsy of hyperechoic lesions and perhaps it should be part of the standard protocol in patients suspected cancer prostate.

[1]  R. Malik,et al.  Transrectal ultrasonography for evaluation of various benign and malignant prostatic lesions and their histopathological correlation , 2004 .

[2]  T. Tammela,et al.  Estimation of prostate cancer risk on the basis of total and free prostate-specific antigen, prostate volume and digital rectal examination. , 2002, European urology.

[3]  P. Littrup,et al.  Prostate cancer: the role of transrectal ultrasound and its impact on cancer detection and management. , 2000, Radiologic clinics of North America.

[4]  G. Durkan,et al.  Diagnostic dilemmas in detection of prostate cancer in patients undergoing transrectal ultrasound-guided needle biopsy of the prostate , 2000, Prostate Cancer and Prostatic Diseases.

[5]  V. Reuter,et al.  Clinical significance of repeat sextant biopsies in prostate cancer patients. , 1997, Urology.

[6]  P. Wingo,et al.  Cancer statistics, 1996 , 1996, CA: a cancer journal for clinicians.

[7]  P. Scardino,et al.  Unusual hyperechoic appearance of prostate cancer on transrectal ultrasonography. , 1992, British journal of urology.

[8]  P. Scardino,et al.  The appearance of prostate cancer on transrectal ultrasonography: correlation of imaging and pathological examinations. , 1989, The Journal of urology.

[9]  N. Dubrawsky Cancer statistics , 1989, CA: a cancer journal for clinicians.

[10]  H. Holm,et al.  Ultrasonically guided precise needle placement in the prostate and the seminal vesicles. , 1981, The Journal of urology.