Reduced heart rate variability in schizophrenia and bipolar disorder compared to healthy controls

Despite current diagnostic systems distinguishing schizophrenia (SZ) and bipolar disorder (BD) as separate diseases, emerging evidence suggests they share a number of clinical and epidemiological features, such as increased cardiovascular disease (CVD) risk. It is not well understood if poor cardiac autonomic nervous system regulation, which can be indexed non‐invasively by the calculation of heart rate variability (HRV), contributes to these common CVD risk factors in both diseases.

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