Genetic Analysis of Receptor-Gαq Coupling Selectivity*
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J. Wess | E. Kostenis | J. Gomeza | C. Lerche
[1] J. Wess. G‐protein‐coupled receptors: molecular mechanisms involved in receptor activation and selectivity of G‐protein recognition , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[2] H. Bourne,et al. How receptors talk to trimeric G proteins. , 1997, Current opinion in cell biology.
[3] S. Karnik,et al. Transducin-α C-terminal Peptide Binding Site Consists of C-D and E-F Loops of Rhodopsin* , 1997, The Journal of Biological Chemistry.
[4] J. Wess,et al. Molecular basis of receptor/G protein coupling selectivity studied by coexpression of wild type and mutant m2 muscarinic receptors with mutant G alpha(q) subunits. , 1997, Biochemistry.
[5] B. Conklin,et al. Carboxyl-terminal mutations of Gq alpha and Gs alpha that alter the fidelity of receptor activation. , 1996, Molecular pharmacology.
[6] H. Khorana,et al. Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study. , 1996, Biochemistry.
[7] H. Hamm,et al. The 2.0 Å crystal structure of a heterotrimeric G protein , 1996, Nature.
[8] H. Hamm,et al. Potent Peptide Analogues of a G Protein Receptor-binding Region Obtained with a Combinatorial Library (*) , 1996, The Journal of Biological Chemistry.
[9] J. Wess. Molecular biology of muscarinic acetylcholine receptors. , 1996, Critical reviews in neurobiology.
[10] E. Weiss,et al. The Effect of Carboxyl-terminal Mutagenesis of G on Rhodopsin and Guanine Nucleotide Binding (*) , 1995, The Journal of Biological Chemistry.
[11] J. Wess,et al. Identification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[12] S. Sprang,et al. The structure of the G protein heterotrimer Giα1 β 1 γ 2 , 1995, Cell.
[13] H. Bourne,et al. Transducin‐alpha C‐terminal mutations prevent activation by rhodopsin: a new assay using recombinant proteins expressed in cultured cells. , 1995, The EMBO journal.
[14] H. Hamm,et al. Structural and functional relationships of heterotrimeric G‐proteins , 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[15] N Blin,et al. Mapping of Single Amino Acid Residues Required for Selective Activation of G by the m3 Muscarinic Acetylcholine Receptor (*) , 1995, The Journal of Biological Chemistry.
[16] M. Brann,et al. Structure-Function of Muscarinic Receptor Coupling to G Proteins , 1995, The Journal of Biological Chemistry.
[17] H. Hamm,et al. Synthetic peptides as probes for G protein function. Carboxyl-terminal G alpha s peptides mimic Gs and evoke high affinity agonist binding to beta-adrenergic receptors. , 1994, The Journal of biological chemistry.
[18] H. Bourne,et al. Activation and depalmitoylation of Gsα , 1994, Cell.
[19] T. Wieland,et al. Transfected muscarinic acetylcholine receptors selectively couple to Gi-type G proteins and Gq/11. , 1994, Molecular pharmacology.
[20] E. Mutschler,et al. Functional role of a cytoplasmic aromatic amino acid in muscarinic receptor-mediated activation of phospholipase C. , 1994, The Journal of biological chemistry.
[21] J. Wess,et al. Identification of an intracellular tyrosine residue critical for muscarinic receptor-mediated stimulation of phosphatidylinositol hydrolysis. , 1994, The Journal of biological chemistry.
[22] C. Strader,et al. Structure and function of G protein-coupled receptors. , 1994, Annual review of biochemistry.
[23] Bruce R. Conklin,et al. Structural elements of Gα subunits that interact with Gβγ, receptors, and effectors , 1993, Cell.
[24] H. Hamm,et al. NMR structure of a receptor-bound G-protein peptide , 1993, Nature.
[25] B. Conklin,et al. Substitution of three amino acids switches receptor specificity of Gqα to that of Giα , 1993, Nature.
[26] J. Baldwin. The probable arrangement of the helices in G protein‐coupled receptors. , 1993, The EMBO journal.
[27] H. Bourne,et al. Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity , 1992, The Journal of cell biology.
[28] M. Brownstein,et al. Molecular cloning and expression of a rat Via arginine vasopressin receptor , 1992, Nature.
[29] C. Fraser,et al. In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptors. , 1992, The Biochemical journal.
[30] B. Kobilka,et al. Adrenergic receptors as models for G protein-coupled receptors. , 1992, Annual review of neuroscience.
[31] J. Wess,et al. Antagonist binding profiles of five cloned human muscarinic receptor subtypes. , 1991, The Journal of pharmacology and experimental therapeutics.
[32] R. Feldman,et al. Molecular cloning of the bombesin/gastrin-releasing peptide receptor from Swiss 3T3 cells. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[33] K. Kameyama,et al. Reconstitutively active G protein-coupled receptors purified from baculovirus-infected insect cells. , 1991, The Journal of biological chemistry.
[34] J. Thorner,et al. Model systems for the study of seven-transmembrane-segment receptors. , 1991, Annual review of biochemistry.
[35] J. Wess,et al. Chimeric m2/m3 muscarinic receptors: role of carboxyl terminal receptor domains in selectivity of ligand binding and coupling to phosphoinositide hydrolysis. , 1990, Molecular pharmacology.
[36] C. Strader,et al. Structural basis of β‐adrenergic receptor function , 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[37] H. Hamm,et al. Site of G protein binding to rhodopsin mapped with synthetic peptides from the alpha subunit. , 1988, Science.
[38] A. Ashkenazi,et al. Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes , 1988, Nature.
[39] D. T. Jones,et al. Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium. , 1987, The Journal of biological chemistry.
[40] T. Bonner,et al. Identification of a family of muscarinic acetylcholine receptor genes. , 1987, Science.
[41] B. Cullen. Use of eukaryotic expression technology in the functional analysis of cloned genes. , 1987, Methods in enzymology.
[42] D Rodbard,et al. Ligand: a versatile computerized approach for characterization of ligand-binding systems. , 1980, Analytical biochemistry.
[43] F. Sanger,et al. DNA sequencing with chain-terminating inhibitors. , 1977, Proceedings of the National Academy of Sciences of the United States of America.
[44] M. M. Bradford. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.
[45] C. Londos,et al. A highly sensitive adenylate cyclase assay. , 1974, Analytical biochemistry.