DNA replication stress restricts ribosomal DNA copy number
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[1] B. Lemos,et al. Genetic context and proliferation determine contrasting patterns of copy number amplification and loss for 5S and 45S ribosomal DNA arrays in cancer , 2017, bioRxiv.
[2] Linheng Li,et al. Ribosomal DNA copy number loss and sequence variation in cancer , 2017, PLoS genetics.
[3] E. Foss,et al. SIR2 suppresses replication gaps and genome instability by balancing replication between repetitive and unique sequences , 2017, Proceedings of the National Academy of Sciences.
[4] Jianmin Wang,et al. A Signature of Genomic Instability Resulting from Deficient Replication Licensing , 2017, PLoS genetics.
[5] P. Mieczkowski,et al. Global analysis of genomic instability caused by DNA replication stress in Saccharomyces cerevisiae , 2016, Proceedings of the National Academy of Sciences.
[6] D. Shore,et al. Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA Replication , 2016, PLoS genetics.
[7] A. C. Simon,et al. Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase , 2016, Molecular cell.
[8] M. Raghuraman,et al. rDNA Copy Number Variants Are Frequent Passenger Mutations in Saccharomyces cerevisiae Deletion Collections and de Novo Transformants , 2016, G3: Genes, Genomes, Genetics.
[9] E. Zackai,et al. Mutations in CDC45, Encoding an Essential Component of the Pre-initiation Complex, Cause Meier-Gorlin Syndrome and Craniosynostosis. , 2016, American journal of human genetics.
[10] Mariko Sasaki,et al. More than 10% of yeast genes are related to genome stability and influence cellular senescence via rDNA maintenance , 2016, Nucleic acids research.
[11] Yuxin Yin,et al. PTEN Controls the DNA Replication Process through MCM2 in Response to Replicative Stress. , 2015, Cell reports.
[12] C. Newlon,et al. Hst3p, a histone deacetylase, promotes maintenance of Saccharomyces cerevisiae chromosome III lacking efficient replication origins , 2015, Molecular Genetics and Genomics.
[13] J. Houseley,et al. Regulation of ribosomal DNA amplification by the TOR pathway , 2015, Proceedings of the National Academy of Sciences.
[14] A. Aguilera,et al. Replication stress and cancer , 2015, Nature Reviews Cancer.
[15] Jianmin Wang,et al. Effect of minichromosome maintenance protein 2 deficiency on the locations of DNA replication origins , 2015, Genome research.
[16] B. Lemos,et al. Concerted copy number variation balances ribosomal DNA dosage in human and mouse genomes , 2015, Proceedings of the National Academy of Sciences.
[17] D. Engelke,et al. A Sequence-Specific Interaction between the Saccharomyces cerevisiae rRNA Gene Repeats and a Locus Encoding an RNA Polymerase I Subunit Affects Ribosomal DNA Stability , 2014, Molecular and Cellular Biology.
[18] B. Lemos,et al. Ribosomal DNA copy number is coupled with gene expression variation and mitochondrial abundance in humans , 2014, Nature Communications.
[19] M. L. Beau,et al. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells , 2014, Nature.
[20] T. Petes,et al. Genome-wide high-resolution mapping of chromosome fragile sites in Saccharomyces cerevisiae , 2014, Proceedings of the National Academy of Sciences.
[21] G. Hattem,et al. The cohesin acetyltransferase Eco1 coordinates rDNA replication and transcription , 2014, EMBO reports.
[22] Takehiko Kobayashi,et al. Rtt109 Prevents Hyper-Amplification of Ribosomal RNA Genes through Histone Modification in Budding Yeast , 2013, PLoS genetics.
[23] L. Kruglyak,et al. A Natural Polymorphism in rDNA Replication Origins Links Origin Activation with Calorie Restriction and Lifespan , 2013, PLoS genetics.
[24] Brian D. Slaughter,et al. Cohesin Proteins Promote Ribosomal RNA Production and Protein Translation in Yeast and Human Cells , 2012, PLoS genetics.
[25] A. Donaldson,et al. Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast , 2011, The EMBO journal.
[26] S. C. Pruitt,et al. Mcm2 deficiency results in short deletions allowing high resolution identification of genes contributing to lymphoblastic lymphoma , 2011, Oncogene.
[27] Jeff Mellen,et al. High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number , 2011, Analytical chemistry.
[28] Takehiko Kobayashi,et al. Monitoring the rate and dynamics of concerted evolution in the ribosomal DNA repeats of Saccharomyces cerevisiae using experimental evolution. , 2011, Molecular biology and evolution.
[29] Bernardo Lemos,et al. Ribosomal DNA Deletions Modulate Genome-Wide Gene Expression: “rDNA–Sensitive” Genes and Natural Variation , 2011, PLoS genetics.
[30] Frederick S. Vizeacoumar,et al. Systematic exploration of essential yeast gene function with temperature-sensitive mutants , 2011, Nature Biotechnology.
[31] Nine V.A.M. Knoers,et al. Mutations in the Pre-Replication Complex cause Meier-Gorlin syndrome , 2011, Nature Genetics.
[32] L. Aragón,et al. Cis-interactions between non-coding ribosomal spacers dependent on RNAP-II separate RNAP-I and RNAP-III transcription domains , 2010, Cell cycle.
[33] S. C. Pruitt,et al. DNA Damage Response and Tumorigenesis in Mcm2 Deficient Mice , 2010, Oncogene.
[34] H. Maki,et al. Abundance of Ribosomal RNA Gene Copies Maintains Genome Integrity , 2010, Science.
[35] Kim Nasmyth,et al. Cohesin: its roles and mechanisms. , 2009, Annual review of genetics.
[36] Israel Steinfeld,et al. BMC Bioinformatics BioMed Central , 2008 .
[37] P. Mieczkowski,et al. Low Levels of DNA Polymerase Alpha Induce Mitotic and Meiotic Instability in the Ribosomal DNA Gene Cluster of Saccharomyces cerevisiae , 2008, PLoS genetics.
[38] Kathryn A. O’Donnell,et al. Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae. , 2008, Molecular cell.
[39] Amy Freeland,et al. Reduced Mcm2 Expression Results in Severe Stem/Progenitor Cell Deficiency and Cancer , 2007, Stem cells.
[40] Miki Ii,et al. Mus81 functions in the quality control of replication forks at the rDNA and is involved in the maintenance of rDNA repeat number in Saccharomyces cerevisiae. , 2007, Mutation research.
[41] Zohar Yakhini,et al. Discovering Motifs in Ranked Lists of DNA Sequences , 2007, PLoS Comput. Biol..
[42] H. Maki,et al. Abnormality in Initiation Program of DNA Replication Is Monitored by the Highly Repetitive rRNA Gene Array on Chromosome XII in Budding Yeast , 2006, Molecular and Cellular Biology.
[43] Takehiko Kobayashi. Strategies to maintain the stability of the ribosomal RNA gene repeats--collaboration of recombination, cohesion, and condensation. , 2006, Genes & genetic systems.
[44] B. Jones,et al. Repeated elements coordinate the spatial organization of the yeast genome , 2006, Yeast.
[45] D. Shore,et al. Spontaneous rDNA copy number variation modulates Sir2 levels and epigenetic gene silencing. , 2005, Genes & development.
[46] M. Nomura,et al. SIR2 Regulates Recombination between Different rDNA Repeats, but Not Recombination within Individual rRNA Genes in Yeast , 2004, Cell.
[47] Takehiko Kobayashi. The Replication Fork Barrier Site Forms a Unique Structure with Fob1p and Inhibits the Replication Fork , 2003, Molecular and Cellular Biology.
[48] M. Nomura,et al. In Exponentially Growing Saccharomyces cerevisiae Cells, rRNA Synthesis Is Determined by the Summed RNA Polymerase I Loading Rate Rather than by the Number of Active Genes , 2003, Molecular and Cellular Biology.
[49] Aaron Bensimon,et al. Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locus. , 2002, Genes & development.
[50] M. Nomura,et al. Transcription Factor UAF, Expansion and Contraction of Ribosomal DNA (rDNA) Repeats, and RNA Polymerase Switch in Transcription of Yeast rDNA , 1999, Molecular and Cellular Biology.
[51] T. Kobayashi,et al. Expansion and contraction of ribosomal DNA repeats in Saccharomyces cerevisiae: requirement of replication fork blocking (Fob1) protein and the role of RNA polymerase I. , 1998, Genes & development.