Sustained activation of NLRP3 inflammasome contributes to delayed wound healing in aged mice.

[1]  Renchang Chen,et al.  Cell death regulation: A new way for natural products to treat osteoporosis. , 2022, Pharmacological research.

[2]  Xianjun Yu,et al.  Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research , 2022, Journal of hematology & oncology.

[3]  Yi Xiong,et al.  Inflammasome Complexes: Crucial mediators in osteoimmunology and bone diseases. , 2022, International immunopharmacology.

[4]  Wenjie He,et al.  Fibroblasts: Immunomodulatory factors in refractory diabetic wound healing , 2022, Frontiers in Immunology.

[5]  Y. Nakahata,et al.  Human Placental Extract Delays In Vitro Cellular Senescence through the Activation of NRF2-Mediated Antioxidant Pathway , 2022, Antioxidants.

[6]  B. Janela,et al.  Age-Related Alterations in Macrophage Distribution and Function Are Associated With Delayed Cutaneous Wound Healing , 2022, Frontiers in Immunology.

[7]  S. Gu,et al.  Young fibroblast-derived exosomal microRNA-125b transfers beneficial effects on aged cutaneous wound healing , 2022, Journal of Nanobiotechnology.

[8]  Lixin Xie,et al.  The advanced glycation end-products (AGEs)/ROS/NLRP3 inflammasome axis contributes to delayed diabetic corneal wound healing and nerve regeneration , 2022, International journal of biological sciences.

[9]  R. Montañez,et al.  Inhibition of the NLRP3 inflammasome improves lifespan in animal murine model of Hutchinson–Gilford Progeria , 2021, EMBO molecular medicine.

[10]  H. Uramoto,et al.  Peroxiredoxin 4 improved aging-related delayed wound healing in mice. , 2021, The Journal of investigative dermatology.

[11]  J. Ge,et al.  Rosuvastatin protects against coronary microembolization-induced cardiac injury via inhibiting NLRP3 inflammasome activation , 2021, Cell death & disease.

[12]  A. Marconi,et al.  Promoter Methylation Leads to Decreased ZFP36 Expression and Deregulated NLRP3 Inflammasome Activation in Psoriatic Fibroblasts , 2021, Frontiers in Medicine.

[13]  Seongju Lee,et al.  Contribution of Autophagy-Notch1-Mediated NLRP3 Inflammasome Activation to Chronic Inflammation and Fibrosis in Keloid Fibroblasts , 2020, International journal of molecular sciences.

[14]  Y. Xiong,et al.  MFG-E8 accelerates wound healing in diabetes by regulating “NLRP3 inflammasome-neutrophil extracellular traps” axis , 2020, Cell death discovery.

[15]  G. López-Castejón,et al.  Mechanisms of NLRP3 priming in inflammaging and age related diseases , 2020, Cytokine & growth factor reviews.

[16]  Haoming Zhou,et al.  Aging aggravated liver ischemia and reperfusion injury by promoting STING‐mediated NLRP3 activation in macrophages , 2020, Aging cell.

[17]  Hao Wu,et al.  An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance. , 2020, Cell metabolism.

[18]  M. Jeschke,et al.  NLRP3 inflammasome activity is required for wound healing after burns. , 2019, Translational research : the journal of laboratory and clinical medicine.

[19]  G. Valacchi,et al.  Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation , 2019, Redox biology.

[20]  Lei Xu,et al.  The selective NLRP3-inflammasome inhibitor MCC950 reduces myocardial fibrosis and improves cardiac remodeling in a mouse model of myocardial infarction. , 2019, International immunopharmacology.

[21]  G. Gurtner,et al.  Age‐associated intracellular superoxide dismutase deficiency potentiates dermal fibroblast dysfunction during wound healing , 2019, Experimental dermatology.

[22]  G. Gurtner,et al.  Wound Healing: A Cellular Perspective. , 2019, Physiological reviews.

[23]  Panfeng Wu,et al.  Metformin induces the M2 macrophage polarization to accelerate the wound healing via regulating AMPK/mTOR/NLRP3 inflammasome singling pathway. , 2019, American journal of translational research.

[24]  E. Latz,et al.  NLRP3 inflammasome activation in inflammaging. , 2018, Seminars in immunology.

[25]  L. Partridge,et al.  Facing up to the global challenges of ageing , 2018, Nature.

[26]  Wenming Zhao,et al.  Aged Mice are More Resistant to Influenza Virus Infection due to Reduced Inflammation and Lung Pathology , 2018, Aging and disease.

[27]  Zhi-jun Hu,et al.  Honokiol alleviates the degeneration of intervertebral disc via suppressing the activation of TXNIP‐NLRP3 inflammasome signal pathway , 2018, Free radical biology & medicine.

[28]  Hiroyasu Ito,et al.  Activation of NLRP3 signalling accelerates skin wound healing , 2018, Experimental dermatology.

[29]  K. Schroder,et al.  NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice. , 2017, Journal of hepatology.

[30]  M. Lamkanfi,et al.  Pyroptosis , 2016, Current Biology.

[31]  G. Gurtner,et al.  Extracellular superoxide dismutase deficiency impairs wound healing in advanced age by reducing neovascularization and fibroblast function , 2016, Experimental dermatology.

[32]  Paul Martin,et al.  Cellular and molecular mechanisms of repair in acute and chronic wound healing , 2015, The British journal of dermatology.

[33]  T. Koh,et al.  Nod-Like Receptor Protein-3 Inflammasome Plays an Important Role during Early Stages of Wound Healing , 2015, PloS one.

[34]  K. Schroder,et al.  A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases , 2015, Nature Medicine.

[35]  R. Kirsner,et al.  Chronic Wound Repair and Healing in Older Adults: Current Status and Future Research , 2015, Journal of the American Geriatrics Society.

[36]  A. Bitto,et al.  Inhibition of inflammasome activation improves the impaired pattern of healing in genetically diabetic mice , 2014, British journal of pharmacology.

[37]  T. Koh,et al.  Sustained Inflammasome Activity in Macrophages Impairs Wound Healing in Type 2 Diabetic Humans and Mice , 2014, Diabetes.

[38]  C. Libert,et al.  The mouse as a model organism in aging research: Usefulness, pitfalls and possibilities , 2013, Ageing Research Reviews.

[39]  B. Cookson,et al.  Pyroptosis: host cell death and inflammation , 2009, Nature Reviews Microbiology.

[40]  S. Werner,et al.  Wound repair and regeneration , 1994, Nature.