DNA damage and metallothionein synthesis in human hepatoma cells (HepG2) exposed to cadmium.

[1]  L. Kaminsky,et al.  Polycyclic aromatic hydrocarbon/metal mixtures: effect on PAH induction of CYP1A1 in human HEPG2 cells. , 2001, Drug metabolism and disposition: the biological fate of chemicals.

[2]  C. Helma,et al.  Evaluation of the single cell gel electrophoresis assay with human hepatoma (Hep G2) cells. , 2000, Mutation research.

[3]  J. Girard,et al.  The nitroxide stable radical tempo prevents metal-induced inhibition of CYP1A1 expression and induction. , 2000, Toxicology letters.

[4]  F. Darroudi,et al.  Genotoxic effects of heterocyclic aromatic amines in human derived hepatoma (HepG2) cells. , 1999, Mutagenesis.

[5]  P López-Ortal,et al.  DNA damage produced by cadmium in a human fetal hepatic cell line. , 1999, Mutation research.

[6]  A. Hartwig.  Carcinogenicity of metal compounds: possible role of DNA repair inhibition. , 1998, Toxicology letters.

[7]  G Williamson,et al.  Use of metabolically competent human hepatoma cells for the detection of mutagens and antimutagens. , 1998, Mutation research.

[8]  M. Waalkes,et al.  Evaluation of the direct genotoxic potential of cadmium in four different rodent cell lines. , 1998, Toxicology.

[9]  M. Chatterjee,et al.  Cadmium-induced alterations of hepatic lipid peroxidation, glutathione S-transferase activity and reduced glutathione level and their possible correlation with chromosomal aberration in mice: a time course study. , 1998, Mutation research.

[10]  A. Hartwig,et al.  Induction and repair inhibition of oxidative DNA damage by nickel(II) and cadmium(II) in mammalian cells. , 1997, Carcinogenesis.

[11]  A. Seidel,et al.  Detection of DNA effects in human cells with the comet assay and their relevance for mutagenesis. , 1996, Toxicology letters.

[12]  D. Bagchi,et al.  Oxidative mechanisms in the toxicity of metal ions. , 1995, Free radical biology & medicine.

[13]  P. Infante,et al.  The scientific fallacy of route specificity of carcinogenesis with particular reference to cadmium. , 1994, Regulatory toxicology and pharmacology : RTP.

[14]  Selected Titles , 1993 .

[15]  D. Beyersmann,et al.  Cadmium and zinc mediated changes of the Ca(2+)-dependent endonuclease in apoptosis. , 1993, Biochemical and biophysical research communications.

[16]  A. Prasad.  Role of metallothionein in human health. , 1992, The Journal of laboratory and clinical medicine.

[17]  A. Natarajan,et al.  Use of human hepatoma cells for in vitro metabolic activation of chemical mutagens/carcinogens. , 1991, Mutagenesis.

[18]  C. Angle,et al.  Effect of sodium butyrate on metallothionein induction and cadmium cytotoxicity in ROS 17/2.8 cells. , 1991, Toxicology.

[19]  J. Abel,et al.  Inhibition of hydroxyl-radical-generated DNA degradation by metallothionein. , 1989, Toxicology letters.

[20]  C. Klaassen,et al.  Comparisons of the toxicity of CdCl2 and Cd-metallothionein in isolated rat hepatocytes. , 1989, Toxicology.

[21]  R. Tice,et al.  A simple technique for quantitation of low levels of DNA damage in individual cells. , 1988, Experimental cell research.

[22]  S. Nocentini.  Inhibition of DNA replication and repair by cadmium in mammalian cells. Protective interaction of zinc. , 1987, Nucleic acids research.

[23]  M. Waalkes,et al.  Enhancement of cadmium-induced metallothionein synthesis in cultured TRL 1215 cells by butyric acid pretreatment. , 1986, Toxicology Letters.

[24]  K. Thakore,et al.  Effect of cadmium chloride on cell division and chromosomes in Chinese Hamster Ovary cells , 1986, Bulletin of environmental contamination and toxicology.

[25]  T. Kjellstrom,et al.  Cancer mortality of cadmium workers. , 1985, British journal of industrial medicine.

[26]  Paul J Thornalley,et al.  Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals. , 1985, Biochimica et biophysica acta.

[27]  T. Mosmann.  Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. , 1983, Journal of immunological methods.

[28]  M. Ohsawa,et al.  Participation of active oxygen species in the induction of DNA single-strand scissions by cadmium chloride in cultured Chinese hamster cells. , 1983, Mutation research.

[29]  B. Goldstein,et al.  Enhancement of rat and human phagocyte superoxide anion radical production by cadmium in vitro. , 1982, Toxicology letters.

[30]  A. Hartwig,et al.  Current aspects in metal genotoxicity , 2004, Biometals.

[31]  Jie Liu,et al.  Metallothionein: an intracellular protein to protect against cadmium toxicity. , 1999, Annual review of pharmacology and toxicology.

[32]  A. Hartmann,et al.  Effect of arsenic and cadmium on the persistence of mutagen‐induced DNA lesions in human cells , 1996, Environmental and molecular mutagenesis.