SRF in Neurochemistry: Overview of Recent Advances in Research on the Nervous System

[1]  A. Tabuchi,et al.  Regulation of Dendritic Synaptic Morphology and Transcription by the SRF Cofactor MKL/MRTF , 2021, Frontiers in Molecular Neuroscience.

[2]  Zsuzsanna Lichner,et al.  MRTF: Basic Biology and Role in Kidney Disease , 2021, International journal of molecular sciences.

[3]  K. Kaibuchi,et al.  Dynamic subcellular localization and transcription activity of the SRF cofactor MKL2 in the striatum are regulated by MAPK , 2021, Journal of neurochemistry.

[4]  D. Gutmann,et al.  SRF Is Required for Maintenance of Astrocytes in Non-Reactive State in the Mammalian Brain , 2021, eNeuro.

[5]  D. Nair,et al.  Vinculin-mediated axon growth requires interaction with actin but not talin in mouse neocortical neurons , 2020, Cellular and Molecular Life Sciences.

[6]  Martin H. Schaefer,et al.  Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains. , 2020, Cell reports.

[7]  I. Takasaki,et al.  Expression of SOLOIST/MRTFB i4, a novel neuronal isoform of the mouse serum response factor coactivator myocardin‐related transcription factor‐B, negatively regulates dendritic complexity in cortical neurons , 2020, Journal of neurochemistry.

[8]  B. Knöll,et al.  Interference with SRF expression in skeletal muscles reduces peripheral nerve regeneration in mice , 2020, Scientific Reports.

[9]  B. Knöll,et al.  Interference of neuronal activity‐mediated gene expression through serum response factor deletion enhances mortality and hyperactivity after traumatic brain injury , 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[10]  L. Kaczmarek,et al.  Loss of serum response factor in mature neurons in the dentate gyrus alters the morphology of dendritic spines and hippocampus-dependent behavioral tasks , 2019, Brain Structure and Function.

[11]  M. Popoli,et al.  SRF and SRFΔ5 Splicing Isoform Recruit Corepressor LSD1/KDM1A Modifying Structural Neuroplasticity and Environmental Stress Response , 2019, Molecular Neurobiology.

[12]  L. M. Valor,et al.  CBP and SRF co-regulate dendritic growth and synaptic maturation , 2019, Cell Death & Differentiation.

[13]  H. Okuno,et al.  Involvement of SRF coactivator MKL2 in BDNF‐mediated activation of the synaptic activity‐responsive element in the Arc gene , 2018, Journal of neurochemistry.

[14]  Jens Michaelis,et al.  Single-molecule imaging of the transcription factor SRF reveals prolonged chromatin-binding kinetics upon cell stimulation , 2018, Proceedings of the National Academy of Sciences.

[15]  E. Nestler,et al.  The dendritic spine morphogenic effects of repeated cocaine use occur through the regulation of serum response factor signaling , 2018, Molecular Psychiatry.

[16]  B. Giros,et al.  Antidepressive effects of targeting ELK-1 signal transduction , 2018, Nature Medicine.

[17]  H. Sakagami,et al.  Synaptic localisation of SRF coactivators, MKL1 and MKL2, and their role in dendritic spine morphology , 2018, Scientific Reports.

[18]  H. Lerche,et al.  SRF modulates seizure occurrence, activity induced gene transcription and hippocampal circuit reorganization in the mouse pilocarpine epilepsy model , 2017, Molecular Brain.

[19]  R. Treisman,et al.  SRF Co-factors Control the Balance between Cell Proliferation and Contractility , 2016, Molecular cell.

[20]  R. Treisman,et al.  Phosphorylation acts positively and negatively to regulate MRTF-A subcellular localisation and activity , 2016, eLife.

[21]  M. Passafaro,et al.  LSD1 modulates stress-evoked transcription of immediate early genes and emotional behavior , 2016, Proceedings of the National Academy of Sciences.

[22]  B. Maček,et al.  Proteomic analysis of SRF associated transcription complexes identified TFII-I as modulator of SRF function in neurons. , 2016, European journal of cell biology.

[23]  H. Fuchs,et al.  Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms , 2016, Molecular Neurobiology.

[24]  A. Nordheim,et al.  Neuronal expression of the transcription factor serum response factor modulates myelination in a mouse multiple sclerosis model , 2015, Glia.

[25]  Zhongming Zhao,et al.  Common variants in the MKL1 gene confer risk of schizophrenia. , 2015, Schizophrenia bulletin.

[26]  L. Kaczmarek,et al.  Adult Deletion of SRF Increases Epileptogenesis and Decreases Activity-Induced Gene Expression , 2015, Molecular Neurobiology.

[27]  T. Shirao,et al.  Cellular localization and dendritic function of rat isoforms of the SRF coactivator MKL1 in cortical neurons , 2014, Neuroreport.

[28]  R. Treisman,et al.  Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts , 2014, Genes & development.

[29]  Anna Oldenborg,et al.  SRF Phosphorylation by Glycogen Synthase Kinase-3 Promotes Axon Growth in Hippocampal Neurons , 2014, The Journal of Neuroscience.

[30]  Stefan Kochanek,et al.  The Transcription Factor Serum Response Factor Stimulates Axon Regeneration through Cytoplasmic Localization and Cofilin Interaction , 2013, The Journal of Neuroscience.

[31]  T. Shirao,et al.  Identification, expression and characterization of rat isoforms of the serum response factor (SRF) coactivator MKL1 , 2013, FEBS open bio.

[32]  B. Cubelos,et al.  Enrichment of Conserved Synaptic Activity-Responsive Element in Neuronal Genes Predicts a Coordinated Response of MEF2, CREB and SRF , 2013, PloS one.

[33]  Ueli Schibler,et al.  Blood-Borne Circadian Signal Stimulates Daily Oscillations in Actin Dynamics and SRF Activity , 2013, Cell.

[34]  L. Kaczmarek,et al.  MKLs: co-factors of serum response factor (SRF) in neuronal responses. , 2012, The international journal of biochemistry & cell biology.

[35]  P. Lu,et al.  A Critical Cell-Intrinsic Role for Serum Response Factor in Glial Specification in the CNS , 2012, The Journal of Neuroscience.

[36]  E. Nestler,et al.  Serum Response Factor and cAMP Response Element Binding Protein Are Both Required for Cocaine Induction of ΔFosB , 2012, The Journal of Neuroscience.

[37]  Evan T. Geller,et al.  Patterns and rates of exonic de novo mutations in autism spectrum disorders , 2012, Nature.

[38]  B. Knöll.  Serum Response Factor Mediated Gene Activity in Physiological and Pathological Processes of Neuronal Motility , 2011, Front. Mol. Neurosci..

[39]  P. Lu,et al.  Serum Response Factor Is Required for Cortical Axon Growth But Is Dispensable for Neurogenesis and Neocortical Lamination , 2011, The Journal of Neuroscience.

[40]  Craig C. Benson,et al.  Identifying functional single nucleotide polymorphisms in the human CArGome. , 2011, Physiological genomics.

[41]  Arnold Munnich,et al.  MED23 Mutation Links Intellectual Disability to Dysregulation of Immediate Early Gene Expression , 2011, Science.

[42]  D. R. Smith,et al.  Effects of serum response factor (SRF) deletion on conditioned reinforcement , 2011, Behavioural Brain Research.

[43]  J. Caboche,et al.  Elk-1 a Transcription Factor with Multiple Facets in the Brain , 2011, Front. Neurosci..

[44]  Donna J. Calu,et al.  Faculty Opinions recommendation of Serum response factor promotes resilience to chronic social stress through the induction of DeltaFosB. , 2010 .

[45]  E. Nestler,et al.  Serum Response Factor Promotes Resilience to Chronic Social Stress through the Induction of ΔFosB , 2010, The Journal of Neuroscience.

[46]  K. Tsuchida,et al.  Involvement of the Serum Response Factor Coactivator Megakaryoblastic Leukemia (MKL) in the Activin-regulated Dendritic Complexity of Rat Cortical Neurons* , 2010, The Journal of Biological Chemistry.

[47]  K. J. Murphy,et al.  Mkl transcription cofactors regulate structural plasticity in hippocampal neurons. , 2010, Cerebral cortex.

[48]  E. Olson,et al.  Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain development , 2010, Development.

[49]  A. Nordheim,et al.  Loss of the serum response factor in the dopamine system leads to hyperactivity , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[50]  J. Miano.  Role of serum response factor in the pathogenesis of disease , 2010, Laboratory Investigation.

[51]  E. Bacchelli,et al.  Linkage and candidate gene studies of autism spectrum disorders in European populations , 2010, European Journal of Human Genetics.

[52]  Alfred Nordheim,et al.  Linking actin dynamics and gene transcription to drive cellular motile functions , 2010, Nature Reviews Molecular Cell Biology.

[53]  B. Knöll,et al.  Serum Response Factor Regulates Hippocampal Lamination and Dendrite Development and Is Connected with Reelin Signaling , 2010, Molecular and Cellular Biology.

[54]  A. Nordheim,et al.  Functional versatility of transcription factors in the nervous system: the SRF paradigm , 2009, Trends in Neurosciences.

[55]  M. Vingron,et al.  Paracrine control of oligodendrocyte differentiation by SRF-directed neuronal gene expression , 2009, Nature Neuroscience.

[56]  Erik Sahai,et al.  Myocardin-Related Transcription Factors and SRF are required for cytoskeletal dynamics, invasion and experimental metastasis , 2009, Nature Cell Biology.

[57]  H. Okuno,et al.  Synaptic activity-responsive element in the Arc/Arg3.1 promoter essential for synapse-to-nucleus signaling in activated neurons , 2009, Proceedings of the National Academy of Sciences.

[58]  S. R. Wickramasinghe,et al.  Serum Response Factor Mediates NGF-Dependent Target Innervation by Embryonic DRG Sensory Neurons , 2008, Neuron.

[59]  T. Morita,et al.  Dual roles of myocardin-related transcription factors in epithelial–mesenchymal transition via slug induction and actin remodeling , 2007, The Journal of cell biology.

[60]  Andrew Brooks,et al.  Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype , 2007, Proceedings of the National Academy of Sciences.

[61]  R. Treisman,et al.  Actin' together: serum response factor, its cofactors and the link to signal transduction. , 2006, Trends in cell biology.

[62]  M. Hetman,et al.  Role of Megakaryoblastic Acute Leukemia-1 in ERK1/2-Dependent Stimulation of Serum Response Factor-Driven Transcription by BDNF or Increased Synaptic Activity , 2006, The Journal of Neuroscience.

[63]  Masaaki Tsuda,et al.  Developmental expression of the SRF co‐activator MAL in brain: role in regulating dendritic morphology , 2006, Journal of neurochemistry.

[64]  Jing Ma,et al.  Acute Myeloid Leukemia-Associated Mkl1 (Mrtf-a) Is a Key Regulator of Mammary Gland Function , 2006, Molecular and Cellular Biology.

[65]  E. Olson,et al.  Requirement of a Myocardin-Related Transcription Factor for Development of Mammary Myoepithelial Cells , 2006, Molecular and Cellular Biology.

[66]  E. Creemers,et al.  The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesis. , 2006, Genes & development.

[67]  R. Treisman,et al.  MAL and Ternary Complex Factor Use Different Mechanisms To Contact a Common Surface on the Serum Response Factor DNA-Binding Domain , 2006, Molecular and Cellular Biology.

[68]  E. Kandel,et al.  A Role in Learning for SRF: Deletion in the Adult Forebrain Disrupts LTD and the Formation of an Immediate Memory of a Novel Context , 2006, Neuron.

[69]  Alfred Nordheim,et al.  Serum response factor controls neuronal circuit assembly in the hippocampus , 2006, Nature Neuroscience.

[70]  C. Stoeckert,et al.  Defining the mammalian CArGome. , 2005, Genome research.

[71]  E. Olson,et al.  Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[72]  J. Baraban,et al.  Nuclear translocation of the SRF co‐activator MAL in cortical neurons: role of RhoA signalling , 2005, Journal of neurochemistry.

[73]  J. Epstein,et al.  Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[74]  Thomas Lemberger,et al.  SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability , 2005, Nature Neuroscience.

[75]  M. Frotscher,et al.  Neuronal migration in the murine rostral migratory stream requires serum response factor , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[76]  R. Prywes,et al.  Myocardin/MKL family of SRF coactivators: Key regulators of immediate early and muscle specific gene expression , 2004, Journal of cellular biochemistry.

[77]  B. Wasylyk,et al.  Ets ternary complex transcription factors. , 2004, Gene.

[78]  Alfred Nordheim,et al.  Mice Deficient for the Ets Transcription Factor Elk-1 Show Normal Immune Responses and Mildly Impaired Neuronal Gene Activation , 2004, Molecular and Cellular Biology.

[79]  R. Prywes,et al.  Megakaryoblastic Leukemia-1/2, a Transcriptional Co-activator of Serum Response Factor, Is Required for Skeletal Myogenic Differentiation* , 2003, Journal of Biological Chemistry.

[80]  S. Morris,et al.  Megakaryoblastic Leukemia 1, a Potent Transcriptional Coactivator for Serum Response Factor (SRF), Is Required for Serum Induction of SRF Target Genes , 2003, Molecular and Cellular Biology.

[81]  R. Treisman,et al.  Actin Dynamics Control SRF Activity by Regulation of Its Coactivator MAL , 2003, Cell.

[82]  Da-Zhi Wang,et al.  Potentiation of serum response factor activity by a family of myocardin-related transcription factors , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[83]  Masao Tanaka,et al.  Identification of a Novel Transcriptional Activator, BSAC, by a Functional Cloning to Inhibit Tumor Necrosis Factor-induced Cell Death* , 2002, The Journal of Biological Chemistry.

[84]  Da-Zhi Wang,et al.  Activation of Cardiac Gene Expression by Myocardin, a Transcriptional Cofactor for Serum Response Factor , 2001, Cell.

[85]  A. Nordheim,et al.  Serum response factor is essential for mesoderm formation during mouse embryogenesis , 1998, The EMBO journal.

[86]  M. Greenberg,et al.  Calcium Influx via the NMDA Receptor Induces Immediate Early Gene Transcription by a MAP Kinase/ERK-Dependent Mechanism , 1996, The Journal of Neuroscience.

[87]  Song Tan,et al.  Structure of serum response factor core bound to DNA , 1995, Nature.

[88]  R. Treisman,et al.  The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF , 1995, Cell.

[89]  A. Sharrocks,et al.  The MADS-box family of transcription factors. , 1995, European journal of biochemistry.

[90]  A. Yueh,et al.  The carboxyl-terminal transactivation domain of human serum response factor contains DNA-activated protein kinase phosphorylation sites. , 1993, The Journal of biological chemistry.

[91]  A. Sharrocks,et al.  Identification of amino acids essential for DNA binding and dimerization in p67SRF: implications for a novel DNA-binding motif , 1993, Molecular and cellular biology.

[92]  Richard Treisman,et al.  Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element , 1988, Cell.

[93]  L. Kedes,et al.  Duplicated CArG box domains have positive and mutually dependent regulatory roles in expression of the human alpha-cardiac actin gene , 1987, Molecular and cellular biology.

[94]  Richard Treisman,et al.  Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors , 1986, Cell.