Angiotensin receptor 1 blocker valsartan normalizes gene expression profiles of 3T3-L1 adipocytes altered by co-culture with LPS-treated RAW264.7 macrophages.
暂无分享,去创建一个
H. Aburatani | T. Asano | H. Sakoda | M. Fujishiro | Y. Nakatsu | A. Kushiyama | H. Kamata | Jun Zhang | Ying Guo | M. Iwashita | F. Nishimura | H. Ohno | Sonoko Kumamoto
[1] I. Komuro,et al. Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes. , 2012, American journal of physiology. Endocrinology and metabolism.
[2] T. Asano,et al. Adipocyte-macrophage interaction may mediate LPS-induced low-grade inflammation: Potential link with metabolic complications , 2012, Innate immunity.
[3] Y. Matsuki,et al. Overexpression of KLF15 Transcription Factor in Adipocytes of Mice Results in Down-regulation of SCD1 Protein Expression in Adipocytes and Consequent Enhancement of Glucose-induced Insulin Secretion* , 2011, The Journal of Biological Chemistry.
[4] J. Després,et al. Adiposity and pulmonary function: relationship with body fat distribution and systemic inflammation. , 2011, Clinical and investigative medicine. Medecine clinique et experimentale.
[5] P. Iglesias,et al. Prevalence of Thyroid Dysfunction in Patients with Type 2 Diabetes , 2011, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.
[6] S. Ghosh,et al. NF-κB, inflammation, and metabolic disease. , 2011, Cell metabolism.
[7] D. Górecka,et al. Proinflammatory cytokines IL-6 and TNF-α and the development of inflammation in obese subjects , 2010, European journal of medical research.
[8] T. Suganami,et al. Adipose tissue macrophages: their role in adipose tissue remodeling , 2010, Journal of leukocyte biology.
[9] O. Okosieme,et al. Thyroid dysfunction in patients with diabetes: clinical implications and screening strategies , 2010, International journal of clinical practice.
[10] Ursula A White,et al. Transcriptional factors that promote formation of white adipose tissue , 2010, Molecular and Cellular Endocrinology.
[11] M. Laakso,et al. Effect of valsartan on the incidence of diabetes and cardiovascular events. , 2010, The New England journal of medicine.
[12] Z. Werb,et al. Matrix Metalloproteinases: Regulators of the Tumor Microenvironment , 2010, Cell.
[13] P. Schauer,et al. Adipocyte Apoptosis, a Link between Obesity, Insulin Resistance, and Hepatic Steatosis* , 2009, The Journal of Biological Chemistry.
[14] Christina K. Chan,et al. Differential Effect of Saturated and Unsaturated Free Fatty Acids on the Generation of Monocyte Adhesion and Chemotactic Factors by Adipocytes , 2009, Diabetes.
[15] H. Matsubara,et al. Effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high cardiovascular risks: KYOTO HEART Study. , 2009, European heart journal.
[16] D. Mazzatti,et al. Microarray analysis identifies matrix metalloproteinases (MMPs) as key genes whose expression is up-regulated in human adipocytes by macrophage-conditioned medium , 2009, Pflügers Archiv - European Journal of Physiology.
[17] D. Fitchett. Results of the ONTARGET and TRANSCEND studies: an update and discussion , 2008, Vascular health and risk management.
[18] S. Aydin,et al. The relationship of inflammatory cytokines with asthma and obesity. , 2008, Clinical and investigative medicine. Medecine clinique et experimentale.
[19] T. Asano,et al. DNA microarray analyses of genes expressed differentially in 3T3-L1 adipocytes co-cultured with murine macrophage cell line RAW264.7 in the presence of the toll-like receptor 4 ligand bacterial endotoxin , 2008, International Journal of Obesity.
[20] C. Glass,et al. A Subpopulation of Macrophages Infiltrates Hypertrophic Adipose Tissue and Is Activated by Free Fatty Acids via Toll-like Receptors 2 and 4 and JNK-dependent Pathways* , 2007, Journal of Biological Chemistry.
[21] S. Takashiba,et al. Macrophage‐Adipocyte Interaction: Marked Interleukin‐6 Production by Lipopolysaccharide , 2007, Obesity.
[22] G. Davis,et al. The role of angiotensin II type 1 receptor blockers in the prevention and management of diabetes mellitus , 2007, Diabetes, obesity & metabolism.
[23] R. Kitazawa,et al. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. , 2006, The Journal of clinical investigation.
[24] T. Suganami,et al. A Paracrine Loop Between Adipocytes and Macrophages Aggravates Inflammatory Changes: Role of Free Fatty Acids and Tumor Necrosis Factor α , 2005, Arteriosclerosis, thrombosis, and vascular biology.
[25] A. Quyyumi,et al. Renin-Angiotensin System and Angiotensin Receptor Blockers in the Metabolic Syndrome , 2004, Circulation.
[26] E. Bruckert,et al. Systemic low-grade inflammation is related to both circulating and adipose tissue TNFα, leptin and IL-6 levels in obese women , 2004, International Journal of Obesity.
[27] Mitchell A. Avery,et al. Identification of Telmisartan as a Unique Angiotensin II: Receptor Antagonist With Selective PPARγ–Modulating Activity , 2004, Hypertension.
[28] L. Tartaglia,et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. , 2003, The Journal of clinical investigation.
[29] M. Karin,et al. AP-1 as a regulator of cell life and death , 2002, Nature Cell Biology.
[30] M. Karin,et al. Missing Pieces in the NF-κB Puzzle , 2002, Cell.
[31] Y. Watanabe,et al. Constitutively active mitogen-activated protein kinase kinase increases GLUT1 expression and recruits both GLUT1 and GLUT4 at the cell surface in 3T3-L1 adipocytes. , 2000, Diabetes.
[32] U. Smith,et al. Culprit Underlying the Metabolic Syndrome and Atherosclerosis , 2007 .
[33] E. Wagner,et al. AP-1: a double-edged sword in tumorigenesis , 2003, Nature Reviews Cancer.