Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer

[1]  M. Ron,et al.  The Secondary Schizophrenias , 2011 .

[2]  Haym Benaroya Science and commerce , 2010 .

[3]  Peter A. Jones,et al.  Epigenetics in cancer. , 2010, Carcinogenesis.

[4]  M. Gallucci,et al.  Genetic profile identification in clinically localized prostate carcinoma. , 2009, Urologic oncology.

[5]  J Miller,et al.  A high-density SNP genome-wide linkage scan in a large autism extended pedigree , 2009, Molecular Psychiatry.

[6]  J. Nurnberger,et al.  Identifying blood biomarkers for mood disorders using convergent functional genomics , 2009, Molecular Psychiatry.

[7]  Michael Wagner,et al.  Neuregulin-1 haplotype HAP(ICE) is associated with lower hippocampal volumes in schizophrenic patients and in non-affected family members. , 2008, Journal of psychiatric research.

[8]  A M McIntosh,et al.  The effects of a neuregulin 1 variant on white matter density and integrity , 2008, Molecular Psychiatry.

[9]  R. Ophoff,et al.  An association screen of myelin-related genes implicates the chromosome 22q11 PIK4CA gene in schizophrenia , 2008, Molecular Psychiatry.

[10]  K. Huse,et al.  High‐resolution mapping of the 8p23.1 beta‐defensin cluster reveals strictly concordant copy number variation of all genes , 2008, Human mutation.

[11]  G. Kirov,et al.  Support for Neuregulin 1 as a Susceptibility Gene for Bipolar Disorder and Schizophrenia , 2008, Biological Psychiatry.

[12]  A. Preti Reduced risk of cancer in schizophrenia: a role for obstetric complications? , 2008, Acta psychiatrica Scandinavica.

[13]  C. DeLisi,et al.  Identification of novel epigenetic markers for clear cell renal cell carcinoma. , 2008, The Journal of urology.

[14]  M. Phillips,et al.  A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder , 2008, Molecular Psychiatry.

[15]  I. Thesleff,et al.  Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes. , 2008, Developmental biology.

[16]  O. Isacson,et al.  Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease. , 2008, Brain : a journal of neurology.

[17]  I. Cobos,et al.  FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development , 2008, Neural Development.

[18]  J. Sutcliffe Insights into the Pathogenesis of Autism , 2008, Science.

[19]  J. Rubenstein,et al.  Frontal cortex subdivision patterning is coordinately regulated by Fgf8, Fgf17, and Emx2 , 2008, The Journal of comparative neurology.

[20]  A. Chase,et al.  Evolutional change of karyotype with t(8;9)(p22;p24) and HLA-DR immunophenotype in relapsed acute myeloid leukemia , 2008, International journal of hematology.

[21]  Anat Achiron,et al.  Breast cancer in women suffering from serious mental illness , 2008, Schizophrenia Research.

[22]  John P A Ioannidis,et al.  Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database , 2008, Nature Genetics.

[23]  D. Geschwind,et al.  Heterogeneous dysregulation of microRNAs across the autism spectrum , 2008, neurogenetics.

[24]  M. Toyota,et al.  Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma , 2008, Journal of Gastroenterology.

[25]  Päivi Heikkilä,et al.  NAD(P)H:quinone oxidoreductase 1 NQO1*2 genotype (P187S) is a strong prognostic and predictive factor in breast cancer , 2008, Nature Genetics.

[26]  Dai Zhang,et al.  Two-stage designs to identify the effects of SNP combinations on complex diseases , 2008, Journal of Human Genetics.

[27]  Claudia Petritsch,et al.  miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells , 2008 .

[28]  S. Nomoto,et al.  Quantitative promoter methylation analysis of hepatocellular carcinoma, cirrhotic and normal liver , 2008, International journal of cancer.

[29]  H. Sekhon,et al.  Activated cholinergic signaling provides a target in squamous cell lung carcinoma. , 2008, Cancer research.

[30]  Jing-ping Zhao,et al.  Explorative study on the expression of neuregulin-1 gene in peripheral blood of schizophrenia , 2008, Neuroscience Letters.

[31]  B. Alger,et al.  Metaplastic control of the endocannabinoid system at inhibitory synapses in hippocampus , 2008, Proceedings of the National Academy of Sciences.

[32]  A. Cesario,et al.  The cholinergic system and cancer. , 2008, Seminars in cancer biology.

[33]  B. Lerer,et al.  Allelic variation in ApoC3, ApoA5 and LPL genes and first and second generation antipsychotic effects on serum lipids in patients with schizophrenia , 2008, The Pharmacogenomics Journal.

[34]  Paul Pavlidis,et al.  Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model , 2008, Nature Genetics.

[35]  S. Gabriel,et al.  Whole-genome association study of bipolar disorder , 2008, Molecular Psychiatry.

[36]  L. Mei,et al.  Neuregulin 1 in neural development, synaptic plasticity and schizophrenia , 2008, Nature Reviews Neuroscience.

[37]  John D Potter,et al.  Genetic susceptibility to cancer: the role of polymorphisms in candidate genes. , 2008, JAMA.

[38]  C. Sumiyoshi,et al.  Calcineurin A gamma and B gene expressions in the whole blood in Japanese patients with schizophrenia , 2008, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[39]  J. Potash,et al.  The genetics of psychotic bipolar disorder , 2008, Current psychiatry reports.

[40]  W. Berrettini,et al.  Association between Polymorphisms in the Vesicular Monoamine Transporter 1 Gene (VMAT1/SLC18A1) on Chromosome 8p and Schizophrenia , 2008, Neuropsychobiology.

[41]  Aaron D. J. Frost,et al.  Cancer incidence in patients with schizophrenia and their first‐degree relatives – a meta‐analysis , 2008, Acta psychiatrica Scandinavica.

[42]  I. Levav,et al.  Enhanced cancer risk among patients with bipolar disorder. , 2008, Journal of affective disorders.

[43]  M. Caligiuri,et al.  MicroRNA expression in cytogenetically normal acute myeloid leukemia. , 2008, The New England journal of medicine.

[44]  Joshua M. Korn,et al.  Mapping and sequencing of structural variation from eight human genomes , 2008, Nature.

[45]  J. Milbrandt,et al.  Mice Lacking the Immediate Early Gene Egr3 Respond to the Anti-Aggressive Effects of Clozapine Yet are Relatively Resistant to its Sedating Effects , 2008, Neuropsychopharmacology.

[46]  A. Regev,et al.  An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors , 2008, Nature Genetics.

[47]  Masatoshi Takeda,et al.  TGFBR2 gene expression and genetic association with schizophrenia. , 2008, Journal of psychiatric research.

[48]  A. Singleton,et al.  Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia , 2008, Science.

[49]  R. Moon,et al.  Wnt5a Control of Cell Polarity and Directional Movement by Polarized Redistribution of Adhesion Receptors , 2008, Science.

[50]  N. Craddock,et al.  Cis- and trans- loci influence expression of the schizophrenia susceptibility gene DTNBP1. , 2008, Human molecular genetics.

[51]  Izuho Hatada,et al.  MeCP2-dependent repression of an imprinted miR-184 released by depolarization. , 2008, Human molecular genetics.

[52]  Marlene Norrby,et al.  Secreted frizzled related protein 1 (Sfrp1) and Wnt signaling in innervated and denervated skeletal muscle , 2008, Journal of Molecular Histology.

[53]  G. Daley,et al.  Selective Blockade of MicroRNA Processing by Lin28 , 2008, Science.

[54]  Paolo Vineis,et al.  A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25 , 2008, Nature.

[55]  L. Mucke,et al.  Abnormal social behaviors in mice lacking Fgf17 , 2008, Genes, brain, and behavior.

[56]  M. Butler,et al.  Array comparative genomic hybridization (aCGH) analysis in Prader–Willi syndrome , 2008, American journal of medical genetics. Part A.

[57]  Lin He,et al.  No association found between the promoter variants of ADRA1A and schizophrenia in the Chinese population. , 2008, Journal of psychiatric research.

[58]  D. Stokoe,et al.  PTEN in brain tumors , 2008, Expert review of neurotherapeutics.

[59]  Jianxin Shi,et al.  No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics. , 2008, The American journal of psychiatry.

[60]  S. Horvath,et al.  Variations in DNA elucidate molecular networks that cause disease , 2008, Nature.

[61]  J. Gallinat,et al.  Association between variation in the vesicular monoamine transporter 1 gene on chromosome 8p and anxiety-related personality traits , 2008, Neuroscience Letters.

[62]  J. Rubenstein,et al.  Compartment-specific transcription factors orchestrate angiogenesis gradients in the embryonic brain , 2008, Nature Neuroscience.

[63]  A. Avogaro,et al.  Oxidative stress and vascular disease in diabetes: is the dichotomization of insulin signaling still valid? , 2008, Free radical biology & medicine.

[64]  George A Calin,et al.  MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia. , 2008, Blood.

[65]  G. Prendergast,et al.  Bin3 deletion causes cataracts and increased susceptibility to lymphoma during aging. , 2008, Cancer research.

[66]  A. Serretti,et al.  The genetics of bipolar disorder: genome ‘hot regions,’ genes, new potential candidates and future directions , 2008, Molecular Psychiatry.

[67]  Vladimir I. Vladimirov,et al.  AKT1 Is Associated with Schizophrenia Across Multiple Symptom Dimensions in the Irish Study of High Density Schizophrenia Families , 2008, Biological Psychiatry.

[68]  Y. Shu,et al.  Genomic alterations in lung adenocarcinomas detected by multicolor fluorescence in situ hybridization and comparative genomic hybridization. , 2008, Cancer genetics and cytogenetics.

[69]  Y. Chagnon,et al.  Differential RNA expression between schizophrenic patients and controls of the dystrobrevin binding protein 1 and neuregulin 1 genes in immortalized lymphocytes , 2008, Schizophrenia Research.

[70]  J. Serratosa,et al.  Autosomal dominant nocturnal frontal lobe epilepsy with a mutation in the CHRNB2 gene , 2008, Epilepsia.

[71]  J. Rahnenführer,et al.  Protein phosphatase and TRAIL receptor genes as new candidate tumor genes on chromosome 8p in prostate cancer. , 2008, Cancer genomics & proteomics.

[72]  P. Dasgupta,et al.  Nicotinic acetylcholine receptors in cancer: multiple roles in proliferation and inhibition of apoptosis. , 2008, Trends in pharmacological sciences.

[73]  G. Mayhew,et al.  Gene‐Gene Interaction Between FGF20 and MAOB in Parkinson Disease , 2008, Annals of human genetics.

[74]  M. Webster,et al.  Elevated neuregulin-1 and ErbB4 protein in the prefrontal cortex of schizophrenic patients , 2008, Schizophrenia Research.

[75]  H. Liu,et al.  NAT2*7 Allele Is a Potential Risk Factor for Adult Brain Tumors in Taiwanese Population , 2008, Cancer Epidemiology Biomarkers & Prevention.

[76]  A. Joyner,et al.  Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development , 2008, Development.

[77]  Michael E Talkowski,et al.  A network of dopaminergic gene variations implicated as risk factors for schizophrenia. , 2008, Human molecular genetics.

[78]  A. Serretti,et al.  Is there protective haplotype of dysbindin gene (DTNBP1) 3 polymorphisms for major depressive disorder , 2008, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[79]  Hanlin Gao,et al.  A novel mutation in JARID1C/SMCX in a patient with autism spectrum disorder (ASD) , 2008, American journal of medical genetics. Part A.

[80]  J. Waddington,et al.  Disruption to social dyadic interactions but not emotional/anxiety-related behaviour in mice with heterozygous ‘knockout’ of the schizophrenia risk gene neuregulin-1 , 2008, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[81]  C. Morton,et al.  Structural genomic variation and personalized medicine. , 2008, The New England journal of medicine.

[82]  Gaofeng Wang,et al.  Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. , 2008, American journal of human genetics.

[83]  D. Pinto,et al.  Structural variation of chromosomes in autism spectrum disorder. , 2008, American journal of human genetics.

[84]  Nobumasa Kato,et al.  Gene expression profiling of major depression and suicide in the prefrontal cortex of postmortem brains , 2008, Neuroscience Research.

[85]  C. Kaltschmidt,et al.  Characterization of a neuregulin-1 gene promoter: positive regulation of type I isoforms by NF-kappaB. , 2008, Biochimica et biophysica acta.

[86]  Kevin A. Pelphrey,et al.  Neural bases for impaired social cognition in schizophrenia and autism spectrum disorders , 2008, Schizophrenia Research.

[87]  R. Schwartz,et al.  Molecular origins of cancer. , 2008, The New England journal of medicine.

[88]  A. Üren,et al.  Wnt-3a and Dickkopf-1 Stimulate Neurite Outgrowth in Ewing Tumor Cells via a Frizzled3- and c-Jun N-Terminal Kinase-Dependent Mechanism , 2008, Molecular and Cellular Biology.

[89]  J. Couzin Gene Tests for Psychiatric Risk Polarize Researchers , 2008, Science.

[90]  M. Cairns,et al.  Dysregulation of miRNA 181b in the temporal cortex in schizophrenia. , 2008, Human molecular genetics.

[91]  Marta Di Forti,et al.  Positional Pathway Screen of wnt Signaling Genes in Schizophrenia: Association with DKK4 , 2008, Biological Psychiatry.

[92]  P. Bouloux,et al.  Diversity in Fibroblast Growth Factor Receptor 1 Regulation: Learning from the Investigation of Kallmann Syndrome , 2007, Journal of neuroendocrinology.

[93]  M. Munafo,et al.  Neuregulin 1 genotype and schizophrenia. , 2007, Schizophrenia bulletin.

[94]  M. Fernando,et al.  The α1-adrenergic receptor antagonist doxazosin inhibits EGFR and NF-κB signalling to induce breast cancer cell apoptosis , 2008 .

[95]  I. V. Kostomarov,et al.  [The relation between gene of lipoprotein-lipase and carrier protein of cholesterol ethers and life duration in patients with chronic cerebral ischemia]. , 2008, Klinicheskaia meditsina.

[96]  M. Fernando,et al.  The alpha1-adrenergic receptor antagonist doxazosin inhibits EGFR and NF-kappaB signalling to induce breast cancer cell apoptosis. , 2008, European journal of cancer.

[97]  Mads Thomassen,et al.  Gene expression meta-analysis identifies chromosomal regions and candidate genes involved in breast cancer metastasis , 2008, Breast Cancer Research and Treatment.

[98]  S. Purcell,et al.  Family-based association study of lithium-related and other candidate genes in bipolar disorder. , 2008, Archives of general psychiatry.

[99]  A. J. Slater,et al.  Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. , 2008, Archives of neurology.

[100]  Jean-Yves Delattre,et al.  Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile , 2008, Molecular Cancer.

[101]  R. Holcombe,et al.  Wnt Pathway-Related Gene Expression in Inflammatory Bowel Disease , 2008, Digestive Diseases and Sciences.

[102]  M. Leboyer,et al.  Association between the PPP3CC gene, coding for the calcineurin gamma catalytic subunit, and bipolar disorder , 2008, Behavioral and Brain Functions.

[103]  D. Weinberger,et al.  Neuregulin-1 Regulates Cell Adhesion via an ErbB2/Phosphoinositide-3 Kinase/Akt-Dependent Pathway: Potential Implications for Schizophrenia and Cancer , 2007, PloS one.

[104]  E. Pennisi,et al.  Human Genetic Variation , 2007, Science.

[105]  Matthew D. Lieberman,et al.  Social cognitive neuroscience: a review of core processes. , 2007, Annual review of psychology.

[106]  M. Shen,et al.  FGF signaling in prostate tumorigenesis--new insights into epithelial-stromal interactions. , 2007, Cancer cell.

[107]  B. Eickholt,et al.  Function of PTEN during the Formation and Maintenance of Neuronal Circuits in the Brain , 2007, Developmental Neuroscience.

[108]  Kohzoh Imai,et al.  Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors. , 2007, Carcinogenesis.

[109]  David Stokoe,et al.  New insights into PTEN , 2007, Journal of Cell Science.

[110]  Satoko Kato,et al.  Calpain‐mediated cleavage of collapsin response mediator protein(CRMP)‐2 during neurite degeneration in mice , 2007, The European journal of neuroscience.

[111]  A. Chase,et al.  Activity of TKI258 against primary cells and cell lines with FGFR1 fusion genes associated with the 8p11 myeloproliferative syndrome. , 2007, Blood.

[112]  L. Bennetto,et al.  Olfaction and Taste Processing in Autism , 2007, Biological Psychiatry.

[113]  Philip M. Kim,et al.  Paired-End Mapping Reveals Extensive Structural Variation in the Human Genome , 2007, Science.

[114]  Xiaohang Zhao,et al.  Identification of Candidate Biomarkers for Hepatocellular Carcinoma Through Pre-Cancerous Expression Analysis in an HBx Transgenic Mouse , 2007, Cancer biology & therapy.

[115]  M. Koga,et al.  Support for association of the PPP3CC gene with schizophrenia , 2007, Molecular Psychiatry.

[116]  N. Itoh The Fgf families in humans, mice, and zebrafish: their evolutional processes and roles in development, metabolism, and disease. , 2007, Biological & pharmaceutical bulletin.

[117]  Xavier Estivill,et al.  Disorders: Filling the Gaps and Exploring Complexity in Genome-Wide Association Studies , 2022 .

[118]  Tsung-Cheng Chang,et al.  microRNAs in vertebrate physiology and human disease. , 2007, Annual review of genomics and human genetics.

[119]  Xin Duan,et al.  Disrupted-In-Schizophrenia 1 Regulates Integration of Newly Generated Neurons in the Adult Brain , 2007, Cell.

[120]  Ole A. Andreassen,et al.  Brain Expressed microRNAs Implicated in Schizophrenia Etiology , 2007, PloS one.

[121]  M. P. Howell,et al.  The immediate early gene early growth response gene 3 mediates adaptation to stress and novelty , 2007, Neuroscience.

[122]  S. Christian,et al.  No evidence for association between 19 cholinergic genes and bipolar disorder , 2007, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[123]  K. Honczarenko,et al.  The role of NAT2 gene polymorphism in aetiology of the most frequent neurodegenerative diseases with dementia. , 2007, Neurologia i neurochirurgia polska.

[124]  Chi-Ying F. Huang,et al.  Chromosomal aberrations of malignant pleural effusions of lung adenocarcinoma: different cytogenetic changes are correlated with genders and smoking habits. , 2007, Lung cancer.

[125]  C. Robson,et al.  Selective over‐expression of fibroblast growth factor receptors 1 and 4 in clinical prostate cancer , 2007, The Journal of pathology.

[126]  S. Hyman Can neuroscience be integrated into the DSM-V? , 2007, Nature Reviews Neuroscience.

[127]  Paul J. Harrison,et al.  Molecular Cloning of a Brain-specific, Developmentally Regulated Neuregulin 1 (NRG1) Isoform and Identification of a Functional Promoter Variant Associated with Schizophrenia*♦ , 2007, Journal of Biological Chemistry.

[128]  H. Hano,et al.  Identification of minimal regions of deletion at 8p23.1‐22 associated with metastasis of hepatocellular carcinoma , 2007, Liver international : official journal of the International Association for the Study of the Liver.

[129]  Y. Meng,et al.  Association studies between the plasmin genes and late-onset Alzheimer's disease , 2007, Neurobiology of Aging.

[130]  Jonathan Sebat,et al.  Major changes in our DNA lead to major changes in our thinking , 2007, Nature Genetics.

[131]  Alfons Meindl,et al.  Copy number variant in the candidate tumor suppressor gene MTUS1 and familial breast cancer risk. , 2007, Carcinogenesis.

[132]  P. Mortensen,et al.  Increased mortality among patients admitted with major psychiatric disorders: a register-based study comparing mortality in unipolar depressive disorder, bipolar affective disorder, schizoaffective disorder, and schizophrenia. , 2007, The Journal of clinical psychiatry.

[133]  Alexander Eckehart Urban,et al.  in the human genome Systematic prediction and validation of breakpoints associated with copy-number variants , 2007 .

[134]  Nobutaka Hattori,et al.  Fibroblast growth factor 20 gene and Parkinson's disease in the Japanese population , 2007, Neuroreport.

[135]  Winnie S. Liang,et al.  GAB2 Alleles Modify Alzheimer's Risk in APOE ɛ4 Carriers , 2007, Neuron.

[136]  M. Katoh Networking of WNT, FGF, Notch, BMP, and Hedgehog Signaling Pathways during Carcinogenesis , 2007, Stem Cell Reviews.

[137]  D. Amaral,et al.  Autoantibodies in Autism Spectrum Disorders (ASD) , 2007, Annals of the New York Academy of Sciences.

[138]  Takashi Suzuki,et al.  Early growth responsive gene 3 in human breast carcinoma: a regulator of estrogen-meditated invasion and a potent prognostic factor. , 2007, Endocrine-related cancer.

[139]  D. Lancet,et al.  Association of the dopamine receptor interacting protein gene, NEF3, with early response to antipsychotic medication. , 2007, The international journal of neuropsychopharmacology.

[140]  L. A. McInnes,et al.  The NRG1 exon 11 missense variant is not associated with autism in the Central Valley of Costa Rica , 2007, BMC psychiatry.

[141]  Luc Girard,et al.  Expression of nicotinic acetylcholine receptor subunit genes in non-small-cell lung cancer reveals differences between smokers and nonsmokers. , 2007, Cancer research.

[142]  H. Miyaoka,et al.  Decreased lipoprotein lipase as a risk factor for atypical neuroleptic-induced hypertriglyceridemia. , 2007, The Journal of clinical psychiatry.

[143]  Paul J. Harrison Schizophrenia Susceptibility Genes and Neurodevelopment , 2007, Biological Psychiatry.

[144]  John G. Sled,et al.  Behavioral Phenotypes of Disc1 Missense Mutations in Mice , 2007, Neuron.

[145]  K. Becker,et al.  Microarray analysis of oxidative stress regulated genes in mesencephalic dopaminergic neuronal cells: Relevance to oxidative damage in Parkinson's disease , 2007, Neurochemistry International.

[146]  G. Opala,et al.  Polymorphisms of catechol-0-methyltransferase (COMT), monoamine oxidase B (MAOB), N-acetyltransferase 2 (NAT2) and cytochrome P450 2D6 (CYP2D6) gene in patients with early onset of Parkinson's disease. , 2007, Parkinsonism & related disorders.

[147]  J. Highton,et al.  Rationale for a trial of immunosuppressive therapy in acute schizophrenia , 2007, Molecular Psychiatry.

[148]  J. Rubenstein,et al.  Patterning of frontal cortex subdivisions by Fgf17 , 2007, Proceedings of the National Academy of Sciences.

[149]  M. Kas,et al.  Genetics of behavioural domains across the neuropsychiatric spectrum; of mice and men , 2007, Molecular Psychiatry.

[150]  J. Enghild,et al.  Proteomic Investigation of the Ventral Rat Hippocampus Links DRP-2 to Escitalopram Treatment Resistance and SNAP to Stress Resilience in the Chronic Mild Stress Model of Depression , 2007, Journal of Molecular Neuroscience.

[151]  M. Nelson,et al.  Profiling of selenomethionine responsive genes in colon cancer by microarray analysis , 2007, Cancer biology & therapy.

[152]  R. Schultz,et al.  Autistic-like symptomatology in Prader-Willi syndrome: A review of recent findings , 2007, Current psychiatry reports.

[153]  C. Grothe,et al.  The physiological and pharmacological role of basic fibroblast growth factor in the dopaminergic nigrostriatal system , 2007, Brain Research Reviews.

[154]  R. Adolphs,et al.  Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity , 2007, Nature Reviews Neuroscience.

[155]  Michael J. Birrer,et al.  Identification of molecular markers and signaling pathway in endometrial cancer in Hong Kong Chinese women by genome-wide gene expression profiling , 2007, Oncogene.

[156]  M. Kastan Wild-Type p53: Tumors Can't Stand It , 2007, Cell.

[157]  S. Faraone,et al.  More evidence supports the association of PPP3CC with schizophrenia , 2007, Molecular Psychiatry.

[158]  Susumu Tonegawa,et al.  Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia , 2007, Proceedings of the National Academy of Sciences.

[159]  M. Fraga,et al.  Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. , 2007, Cancer research.

[160]  M. de Castro,et al.  Clinical assessment and molecular analysis of GnRHR and KAL1 genes in males with idiopathic hypogonadotrophic hypogonadism , 2007, Clinical endocrinology.

[161]  No association between PPP3CC and schizophrenia in the Chinese population , 2007, Schizophrenia Research.

[162]  Y. Liou,et al.  Support for association of the A277C single nucleotide polymorphism in human vesicular monoamine transporter 1 gene with schizophrenia , 2007, Schizophrenia Research.

[163]  J. Steele,et al.  Genetics of recurrent early-onset major depression (GenRED): final genome scan report. , 2007, The American journal of psychiatry.

[164]  I. Levav,et al.  Cancer risk among parents and siblings of patients with schizophrenia , 2007, British Journal of Psychiatry.

[165]  P Shaw,et al.  Neuregulin 1 (8p12) and childhood-onset schizophrenia: susceptibility haplotypes for diagnosis and brain developmental trajectories , 2007, Molecular Psychiatry.

[166]  Peter Falkai,et al.  Immunohistochemical Evidence for Impaired Neuregulin‐1 Signaling in the Prefrontal Cortex in Schizophrenia and in Unipolar Depression , 2007, Annals of the New York Academy of Sciences.

[167]  S. Britsch Introduction: Molecular control of development , 2007 .

[168]  E. Pennisi Breakthrough of the year. Human genetic variation. , 2007, Science.

[169]  Winnie S. Liang,et al.  GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers. , 2007, Neuron.

[170]  J. Rubenstein,et al.  Genetic regulation of prefrontal cortex development and function. , 2007, Novartis Foundation symposium.

[171]  D. Butterfield,et al.  Proteomics analysis of the Alzheimer's disease hippocampal proteome. , 2007, Journal of Alzheimer's disease : JAD.

[172]  No association between a functional NAD(P)H , 2007, NeuroMolecular Medicine.

[173]  D. Blackwood,et al.  Association of Neuregulin 1 with schizophrenia and bipolar disorder in a second cohort from the Scottish population , 2007, Molecular Psychiatry.

[174]  Stefan Britsch,et al.  The neuregulin-I/ErbB signaling system in development and disease. , 2007, Advances in anatomy, embryology, and cell biology.

[175]  K. Lesch,et al.  FZD3 is not a risk gene for schizophrenia: a case-control study in a Caucasian sample. , 2007, Journal of neural transmission. Supplementum.

[176]  Joel S Parker,et al.  microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder , 2007, Genome Biology.

[177]  R. Canitano Epilepsy in autism spectrum disorders , 2007, European Child & Adolescent Psychiatry.

[178]  R. Tabarés-Seisdedos,et al.  Variations in genes regulating neuronal migration predict reduced prefrontal cognition in schizophrenia and bipolar subjects from mediterranean Spain: A preliminary study , 2006, Neuroscience.

[179]  M. Brüne,et al.  Theory of mind—evolution, ontogeny, brain mechanisms and psychopathology , 2006, Neuroscience & Biobehavioral Reviews.

[180]  E. Torrey,et al.  Prostate cancer and schizophrenia. , 2006, Urology.

[181]  J. Biswas,et al.  Expressions of Rac1, Tiam1 and Cdc42 in retinoblastoma. , 2006, Experimental eye research.

[182]  Lin He,et al.  An investigation of the dihydropyrimidinase-like 2 (DPYSL2) gene in schizophrenia: genetic association study and expression analysis. , 2006, The international journal of neuropsychopharmacology.

[183]  Heather C Whalley,et al.  A neuregulin 1 variant associated with abnormal cortical function and psychotic symptoms , 2006, Nature Neuroscience.

[184]  K. Arima,et al.  Behavioral and Brain Functions Association Study of the Vesicular Monoamine Transporter 1 (vmat1) Gene with Schizophrenia in a Japanese Population , 2022 .

[185]  G. Dawson,et al.  Evidence for multiple loci from a genome scan of autism kindreds , 2006, Molecular Psychiatry.

[186]  Paola Bovolenta,et al.  Frizzled/RYK mediated signalling in axon guidance , 2006, Development.

[187]  Sonja W. Scholz,et al.  Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data , 2006, The Lancet Neurology.

[188]  Y. Shoenfeld,et al.  To smell the immune system: olfaction, autoimmunity and brain involvement. , 2006, Autoimmunity reviews.

[189]  J. LaSalle,et al.  Reduced MeCP2 Expression is Frequent in Autism Frontal Cortex and Correlates with Aberrant MECP2 Promoter Methylation , 2006, Epigenetics.

[190]  J. Millonig,et al.  En2 knockout mice display neurobehavioral and neurochemical alterations relevant to autism spectrum disorder , 2006, Brain Research.

[191]  A. Brooks-Kayal,et al.  Brain-derived Neurotrophic Factor (BDNF)-induced Synthesis of Early Growth Response Factor 3 (Egr3) Controls the Levels of Type A GABA Receptorα4 Subunits in Hippocampal Neurons* , 2006, Journal of Biological Chemistry.

[192]  R. McKay,et al.  A Specific Survival Response in Dopamine Neurons at Most Risk in Parkinson's Disease , 2006, The Journal of Neuroscience.

[193]  C Caldas,et al.  High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation , 2006, Oncogene.

[194]  S. Spence,et al.  Stratification based on language‐related endophenotypes in autism: Attempt to replicate reported linkage , 2006, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[195]  Bernhard Radlwimmer,et al.  A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon. , 2006, American journal of human genetics.

[196]  C. Carney,et al.  Medical Comorbidity in Women and Men With Bipolar Disorders: A Population-Based Controlled Study , 2006, Psychosomatic medicine.

[197]  R. Houlston,et al.  Meta-analysis and pooled re-analysis of copy number changes in colorectal cancer detected by comparative genomic hybridization. , 2006, Anticancer research.

[198]  M. Walton,et al.  A Role for the Macaque Anterior Cingulate Gyrus in Social Valuation , 2006, Science.

[199]  J. Poirier,et al.  A polymorphism in lipoprotein lipase affects the severity of Alzheimer's disease pathophysiology , 2006, The European journal of neuroscience.

[200]  Jürgen Gallinat,et al.  Variations in the Vesicular Monoamine Transporter 1 Gene (VMAT1/SLC18A1) are Associated with Bipolar I Disorder , 2006, Neuropsychopharmacology.

[201]  M. Webster,et al.  Gene expression analysis of bipolar disorder reveals downregulation of the ubiquitin cycle and alterations in synaptic genes , 2006, Molecular Psychiatry.

[202]  D. Hochstrasser,et al.  Changes of the cortex proteome and Apolipoprotein E in transgenic mouse models of Alzheimer's Disease. , 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[203]  L. Almasy,et al.  Linkage disequilibrium analyses in the Costa Rican population suggests discrete gene loci for schizophrenia at 8p23.1 and 8q13.3 , 2006, Psychiatric genetics.

[204]  M. Iyo,et al.  Association Study of the Dihydropyrimidinase‐Related Protein 2 Gene and Methamphetamine Psychosis , 2006, Annals of the New York Academy of Sciences.

[205]  Steve Morgan,et al.  The Common Drug Review: a NICE start for Canada? , 2006, Health policy.

[206]  S. Roche,et al.  First family-based test for association of neuregulin with bipolar affective disorder , 2006, Molecular Psychiatry.

[207]  David Curtis,et al.  Genetic association and brain morphology studies and the chromosome 8p22 pericentriolar material 1 (PCM1) gene in susceptibility to schizophrenia. , 2006, Archives of general psychiatry.

[208]  P. Sedgwick,et al.  Hippocampal FGF-2 and FGFR1 mRNA expression in major depression, schizophrenia and bipolar disorder , 2006, Brain Research Bulletin.

[209]  Paul J. Harrison,et al.  Neuregulin 1 and Schizophrenia: Genetics, Gene Expression, and Neurobiology , 2006, Biological Psychiatry.

[210]  J. Bobes,et al.  N-acetyltransferase-2 polymorphisms and schizophrenia , 2006, European Psychiatry.

[211]  Karin E. Borgmann-Winter,et al.  Altered neuregulin 1–erbB4 signaling contributes to NMDA> receptor hypofunction in schizophrenia , 2006, Nature Medicine.

[212]  J. Todd Statistical false positive or true disease pathway? , 2006, Nature Genetics.

[213]  S. Ying,et al.  First in vivo evidence of microRNA-induced fragile X mental retardation syndrome , 2006, Molecular Psychiatry.

[214]  Y. Ahn,et al.  Investigation of genetic association between human Frizzled homolog 3 gene (FZD3) and schizophrenia: Results in a Korean population and evidence from meta-analysis , 2006, Psychiatry Research.

[215]  S. Hyman,et al.  Can Autism Speak to Neuroscience? , 2006, The Journal of Neuroscience.

[216]  A. Jablensky,et al.  Subtyping schizophrenia: implications for genetic research , 2006, Molecular Psychiatry.

[217]  Lin He,et al.  Meta-analysis shows strong positive association of the neuregulin 1 (NRG1) gene with schizophrenia. , 2006, Human molecular genetics.

[218]  Tushar Patel,et al.  Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. , 2006, Gastroenterology.

[219]  R. Hard,et al.  Fibroblast growth factor receptor signaling affects development and function of dopamine neurons – inhibition results in a schizophrenia‐like syndrome in transgenic mice , 2006, Journal of Neurochemistry.

[220]  Kyla Pennington,et al.  Proteomic analysis of the anterior cingulate cortex in the major psychiatric disorders: Evidence for disease‐associated changes , 2006, Proteomics.

[221]  M. Munafo,et al.  Association of the NRG1 gene and schizophrenia: a meta-analysis , 2006, Molecular Psychiatry.

[222]  Paul J. Harrison,et al.  Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[223]  D. Servent,et al.  Development of novel therapeutic strategies for lung cancer: targeting the cholinergic system. , 2006, Current medicinal chemistry.

[224]  K. Papanikolaou,et al.  A Case of Partial Trisomy of Chromosome 8p Associated with Autism , 2006, Journal of autism and developmental disorders.

[225]  O. Marín,et al.  Tangential Neuronal Migration Controls Axon Guidance: A Role for Neuregulin-1 in Thalamocortical Axon Navigation , 2006, Cell.

[226]  B. Dean,et al.  Postmortem brain calcineurin protein levels in schizophrenia patients are not different from controls , 2006, Schizophrenia Research.

[227]  W. Liu,et al.  Association analyses of the neuregulin 1 gene with schizophrenia and manic psychosis in a Hispanic population , 2006, Acta psychiatrica Scandinavica.

[228]  K. Ess The neurobiology of tuberous sclerosis complex. , 2006, Seminars in pediatric neurology.

[229]  T. Gilliam,et al.  Genome-wide linkage scan in a large bipolar disorder sample from the National Institute of Mental Health genetics initiative suggests putative loci for bipolar disorder, psychosis, suicide, and panic disorder , 2006, Molecular Psychiatry.

[230]  Tak W. Mak,et al.  Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis , 2006, Nature Reviews Cancer.

[231]  R. Jaenisch,et al.  Postnatal Loss of Methyl-CpG Binding Protein 2 in the Forebrain is Sufficient to Mediate Behavioral Aspects of Rett Syndrome in Mice , 2006, Biological Psychiatry.

[232]  E. Grove,et al.  Area and layer patterning in the developing cerebral cortex , 2006, Current Opinion in Neurobiology.

[233]  Pablo V Gejman,et al.  Genomewide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample. , 2006, American journal of human genetics.

[234]  Susumu Mori,et al.  Axonal Growth and Guidance Defects in Frizzled3 Knock-Out Mice: A Comparison of Diffusion Tensor Magnetic Resonance Imaging, Neurofilament Staining, and Genetically Directed Cell Labeling , 2006, The Journal of Neuroscience.

[235]  F. Tyson,et al.  Environmental Epigenomics, Imprinting and Disease Susceptibility , 2006, Epigenetics.

[236]  T. Insel,et al.  Cure therapeutics and strategic prevention: raising the bar for mental health research , 2006, Molecular Psychiatry.

[237]  J. Borlak,et al.  N-acetyltransferase 2 (NAT2) gene polymorphisms in Parkinson's disease , 2006, BMC Medical Genetics.

[238]  Eric Fombonne,et al.  Epidemiology of autistic disorder and other pervasive developmental disorders. , 2005, The Journal of clinical psychiatry.

[239]  Cheryl Corcoran,et al.  Olfactory deficits, cognition and negative symptoms in early onset psychosis , 2005, Schizophrenia Research.

[240]  Paul J. Harrison,et al.  Differential expression of calcineurin A subunit mRNA isoforms during rat hippocampal and cerebellar development , 2005, The European journal of neuroscience.

[241]  R. Huganir,et al.  Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. , 2005, American journal of human genetics.

[242]  E. I. Rogaev,et al.  Small RNAs in Human Brain Development and Disorders , 2005, Biochemistry (Moscow).

[243]  C. Pato,et al.  Human p53 tumor suppressor gene (TP53) and schizophrenia: Case–control and family studies , 2005, Neuroscience Letters.

[244]  T. Nielsen,et al.  NRG1 gene rearrangements in clinical breast cancer: identification of an adjacent novel amplicon associated with poor prognosis , 2005, Oncogene.

[245]  John M Greally,et al.  Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes , 2005, BMC Genomics.

[246]  D. Pinkel,et al.  Genomic microarray analysis identifies candidate loci in patients with corpus callosum anomalies , 2005, Neurology.

[247]  B. Devlin,et al.  Neuregulin‐1 polymorphism in late onset Alzheimer's disease families with psychoses , 2005, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[248]  M. Sur,et al.  Patterning and Plasticity of the Cerebral Cortex , 2005, Science.

[249]  Mike Bly,et al.  Mutation in the vesicular monoamine gene, SLC18A1, associated with schizophrenia , 2005, Schizophrenia Research.

[250]  Jacques Corbeil,et al.  Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[251]  R Freedman,et al.  Differential modulation of gene expression in the NMDA postsynaptic density of schizophrenic and control smokers. , 2005, Brain research. Molecular brain research.

[252]  U. Muthane,et al.  Association of N-acetyl transferase 2 gene polymorphism and slow acetylator phenotype with young onset and late onset Parkinson's disease among Indians , 2005, Pharmacogenetics and genomics.

[253]  Peter A. Jones,et al.  Mechanisms of Disease: genetic and epigenetic alterations that drive bladder cancer , 2005, Nature Clinical Practice Urology.

[254]  R. Kerwin,et al.  Polymorphisms in the Promoter Region of the Alpha1A-Adrenoceptor Gene Are Associated with Schizophrenia/Schizoaffective Disorder in a Spanish Isolate Population , 2005, Biological Psychiatry.

[255]  R. Kessler,et al.  The economic burden of schizophrenia in the United States in 2002. , 2005, The Journal of clinical psychiatry.

[256]  C. Roehrborn,et al.  A double-blind placebo-controlled study evaluating the onset of action of doxazosin gastrointestinal therapeutic system in the treatment of benign prostatic hyperplasia. , 2005, European urology.

[257]  M J Owen,et al.  Schizophrenia: genes at last? , 2005, Trends in genetics : TIG.

[258]  Y. Liou,et al.  Association analysis of NAD(P)Hratioquinone oxidoreductase (NQO1) Pro187Ser genetic polymorphism and tardive dyskinesia in patients with schizophrenia in Taiwan. , 2005, The international journal of neuropsychopharmacology.

[259]  Hongkai Ji,et al.  Why do human diversity levels vary at a megabase scale? , 2005, Genome research.

[260]  A. Brooks-Kayal,et al.  Egr3 stimulation of GABRA4 promoter activity as a mechanism for seizure-induced up-regulation of GABA(A) receptor alpha4 subunit expression. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[261]  M. Momoi,et al.  Mutation analysis of methyl-CpG binding protein family genes in autistic patients , 2005, Brain and Development.

[262]  Andreas Papassotiropoulos,et al.  A cluster of cholesterol-related genes confers susceptibility for Alzheimer's disease. , 2005, The Journal of clinical psychiatry.

[263]  R. Buchanan,et al.  Dihydropyrimidinase‐related protein 2 (DRP‐2) gene and association to deficit and nondeficit schizophrenia , 2005, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[264]  H. Yao,et al.  The tumor suppressor adenomatous polyposis coli gene is associated with susceptibility to schizophrenia , 2005, Molecular Psychiatry.

[265]  W. Berrettini,et al.  No association between common variations in the neuronal nicotinic acetylcholine receptor alpha2 subunit gene (CHRNA2) and bipolar I disorder , 2005, Psychiatry Research.

[266]  A. Singleton,et al.  Lack of evidence for a genetic association between FGF20 and Parkinson's disease in Finnish and Greek patients , 2005, BMC neurology.

[267]  P. Mortensen,et al.  Risk for schizophrenia and schizophrenia-like psychosis among patients with epilepsy: population based cohort study , 2005, BMJ : British Medical Journal.

[268]  G. Kirov,et al.  Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder. , 2005, Archives of general psychiatry.

[269]  J. Haines,et al.  An autosomal genomic screen for dementia in an extended Amish family , 2005, Neuroscience Letters.

[270]  F. Fumagalli,et al.  Emerging role of the FGF system in psychiatric disorders. , 2005, Trends in pharmacological sciences.

[271]  Y. Chagnon,et al.  Shared and specific susceptibility loci for schizophrenia and bipolar disorder: a dense genome scan in Eastern Quebec families , 2005, Molecular Psychiatry.

[272]  Paul J. Harrison,et al.  Decreased hippocampal expression of the susceptibility gene PPP3CC and other calcineurin subunits in schizophrenia , 2005, Biological Psychiatry.

[273]  C. Dickson,et al.  Fibroblast growth factor signaling in tumorigenesis. , 2005, Cytokine & growth factor reviews.

[274]  D. Ambrosetti,et al.  Mechanisms underlying differential responses to FGF signaling. , 2005, Cytokine & growth factor reviews.

[275]  D. Storm,et al.  The role of calmodulin as a signal integrator for synaptic plasticity , 2005, Nature Reviews Neuroscience.

[276]  I. Levav,et al.  Cancer in schizophrenia: is the risk higher or lower? , 2005, Schizophrenia Research.

[277]  C. Aston,et al.  Original Research Article , 2004 .

[278]  L. Zwaigenbaum,et al.  A Girl with Pervasive Developmental Disorder and Complex Chromosome Rearrangement Involving 8p and 10p , 2005, Journal of autism and developmental disorders.

[279]  J. Bodfish,et al.  The early development of stereotypy and self-injury: a review of research methods. , 2005, Journal of intellectual disability research : JIDR.

[280]  K. Kaibuchi,et al.  GSK-3β Regulates Phosphorylation of CRMP-2 and Neuronal Polarity , 2005, Cell.

[281]  Christian Dina,et al.  Fine mapping of a region on chromosome 8p gives evidence for a QTL contributing to individual differences in an anxiety‐related personality trait: TPQ harm avoidance , 2005, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[282]  N. Cairns,et al.  Candidate gene association studies of genes involved in neuronal cholinergic transmission in Alzheimer's disease suggests choline acetyltransferase as a candidate deserving further study , 2005, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[283]  吉村 武 GSK-3β regulates phosphorylation of CRMP-2 and neuronal polarity , 2005 .

[284]  D. Perkins,et al.  Expanding the ‘central dogma’: the regulatory role of nonprotein coding genes and implications for the genetic liability to schizophrenia , 2005, Molecular Psychiatry.

[285]  S. Purcell,et al.  Support for involvement of neuregulin 1 in schizophrenia pathophysiology , 2005, Molecular Psychiatry.

[286]  T. Suzuki,et al.  No association with the calcineurin A gamma subunit gene (PPP3CC) haplotype to Japanese schizophrenia , 2005, Journal of Neural Transmission.

[287]  T. Suzuki,et al.  Association study of the frizzled-3 (FZD3) gene with schizophrenia and mood disorders , 2005, Journal of Neural Transmission.

[288]  C. Robson,et al.  Fibroblast growth factor 17 is over‐expressed in human prostate cancer , 2004, The Journal of pathology.

[289]  C. Papageorgiou,et al.  Kallmann's Syndrome and Schizophrenia , 2004, International journal of psychiatry in medicine.

[290]  Soo-Jung Lee,et al.  Quinone oxidoreductase (NQO1) gene polymorphism (609C/T) may be associated with tardive dyskinesia, but not with the development of schizophrenia. , 2004, The international journal of neuropsychopharmacology.

[291]  T. Gilliam,et al.  Linkage analysis of psychosis in bipolar pedigrees suggests novel putative loci for bipolar disorder and shared susceptibility with schizophrenia , 2004, Molecular Psychiatry.

[292]  P. Visscher,et al.  A genome scan and follow-up study identify a bipolar disorder susceptibility locus on chromosome 1q42 , 2004, Molecular Psychiatry.

[293]  M. Tsao,et al.  Identification of 27 5′ CpG islands aberrantly methylated and 13 genes silenced in human pancreatic cancers , 2004, Oncogene.

[294]  D. Louis,et al.  Loss of p53 sensitizes mice with a mutation in Ccm1 (KRIT1) to development of cerebral vascular malformations. , 2004, The American journal of pathology.

[295]  E G Jones,et al.  Dysregulation of the fibroblast growth factor system in major depression. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[296]  G. He,et al.  Tumor suppressor gene TP53 is genetically associated with schizophrenia in the Chinese population , 2004, Neuroscience Letters.

[297]  R. Nusse,et al.  The Wnt signaling pathway in development and disease. , 2004, Annual review of cell and developmental biology.

[298]  Carlos Caldas,et al.  A Recurrent Chromosome Breakpoint in Breast Cancer at the NRG1/Neuregulin 1/Heregulin Gene , 2004, Cancer Research.

[299]  T. Asada,et al.  Genetic and expression analyses of FZD3 in schizophrenia , 2004, Biological Psychiatry.

[300]  G. Moretto,et al.  The H+ allele of the lipoprotein lipase (LPL) HindIII intronic polymorphism and the risk for sporadic late-onset Alzheimer’s disease , 2004, Neuroscience Letters.

[301]  Q. Ma,et al.  N-Acetyltransferase 2 gene polymorphism in a group of senile dementia patients in Shanghai suburb. , 2004, Acta pharmacologica Sinica.

[302]  Jun Wei,et al.  Lack of a genetic association between the frizzled-3 gene and schizophrenia in a British population , 2004, Neuroscience Letters.

[303]  B. Maher,et al.  Genome‐wide linkage survey for genetic loci that affect the risk of suicide attempts in families with recurrent, early‐onset, major depression , 2004, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[304]  Xin Yu,et al.  Positive association of the human frizzled 3 (FZD3) gene haplotype with schizophrenia in Chinese Han population , 2004, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[305]  Kenny Q. Ye,et al.  Large-Scale Copy Number Polymorphism in the Human Genome , 2004, Science.

[306]  N. Craddock,et al.  MECP2 structural and 3′‐UTR variants in schizophrenia, autism and other psychiatric diseases: A possible association with autism , 2004, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[307]  L. Fañanás,et al.  Analysis of polymorphisms at the tumor suppressor gene p53 (TP53) in contributing to the risk for schizophrenia and its associated neurocognitive deficits , 2004, Neuroscience Letters.

[308]  Eden R Martin,et al.  Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease. , 2004, American journal of human genetics.

[309]  Ming T. Tsuang,et al.  A Novel Permutation Testing Method Implicates Sixteen Nicotinic Acetylcholine Receptor Genes as Risk Factors for Smoking in Schizophrenia Families , 2004, Human Heredity.

[310]  J. Buxbaum,et al.  Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia , 2004, Nature Neuroscience.

[311]  C. Francks,et al.  Genome-wide scan of reading ability in affected sibling pairs with attention-deficit/hyperactivity disorder: unique and shared genetic effects , 2004, Molecular Psychiatry.

[312]  Eva Forssell-Aronsson,et al.  Importance of Vesicle Proteins in the Diagnosis and Treatment of Neuroendocrine Tumors , 2004, Annals of the New York Academy of Sciences.

[313]  E K Perry,et al.  Autism as a disorder of neural information processing: directions for research and targets for therapy* , 2004, Molecular Psychiatry.

[314]  W. Gerald,et al.  Gene expression profiling predicts clinical outcome of prostate cancer. , 2004, The Journal of clinical investigation.

[315]  R. Petersen,et al.  An association study of the cholesteryl ester transfer protein TaqI B polymorphism with late onset Alzheimer's disease , 2004, Neuroscience Letters.

[316]  JaneR . Taylor,et al.  Loss of Glutamatergic Pyramidal Neurons in Frontal and Temporal Cortex Resulting from Attenuation of Fgfr1 Signaling Is Associated with Spontaneous Hyperactivity in Mice , 2022 .

[317]  J. W. Kim,et al.  Differences in p53 gene polymorphisms between Korean schizophrenia and lung cancer patients , 2004, Schizophrenia Research.

[318]  R Hashimoto,et al.  Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia , 2004, Molecular Psychiatry.

[319]  Sheng-tian Li,et al.  Critical Role of Calpain-mediated Cleavage of Calcineurin in Excitotoxic Neurodegeneration* , 2004, Journal of Biological Chemistry.

[320]  I. Dunham,et al.  DNA sequence and analysis of human chromosome 9 , 2003, Nature.

[321]  D. Malaspina,et al.  Olfactory identification and WAIS-R performance in deficit and nondeficit schizophrenia , 2003, Schizophrenia Research.

[322]  H. Simmonds,et al.  Dihydropyrimidinase deficiency presenting in infancy with severe developmental delay , 1993, Journal of Inherited Metabolic Disease.

[323]  Jack A. Taylor,et al.  N-acetyl transferase genotypes in relation to risk of developing systemic lupus erythematosus. , 2004, The Journal of rheumatology.

[324]  C. Gundersen,et al.  Convergent Effects of Lithium and Valproate on the Expression of Proteins Associated with Large Dense Core Vesicles in NGF-differentiated PC12 Cells , 2004, Neuropsychopharmacology.

[325]  A. Llerena,et al.  Acetylator polymorphism in Parkinson's disease , 2004, European Journal of Clinical Pharmacology.

[326]  M. Budge,et al.  NAT gene polymorphisms and susceptibility to Alzheimer's disease: identification of a novel NAT1 allelic variant , 2004, BMC Medical Genetics.

[327]  H. Ujike,et al.  The human frizzled-3 (FZD3) gene on chromosome 8p21, a receptor gene for Wnt ligands, is associated with the susceptibility to schizophrenia , 2003, Neuroscience Letters.

[328]  Hongyan Zhang,et al.  Association study of the human FZD3 locus with schizophrenia , 2003, Biological Psychiatry.

[329]  B. Maher,et al.  Genome‐wide linkage survey for genetic loci that influence the development of depressive disorders in families with recurrent, early‐onset, major depression , 2003, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[330]  H. Ujike,et al.  No association between the dihydropyrimidinase-related protein 2 (DRP-2) gene and bipolar disorder in humans , 2003, Neuroscience Letters.

[331]  D. Huylebroeck,et al.  Slowed conduction and thin myelination of peripheral nerves associated with mutant rho Guanine-nucleotide exchange factor 10. , 2003, American journal of human genetics.

[332]  H. Groenewegen,et al.  The medial prefrontal cortex in the rat: evidence for a dorso-ventral distinction based upon functional and anatomical characteristics , 2003, Neuroscience & Biobehavioral Reviews.

[333]  D. Birnbaum,et al.  Chromosome arm 8p and cancer: a fragile hypothesis. , 2003, The Lancet. Oncology.

[334]  P. Goldman-Rakic,et al.  Dopamine receptor-interacting proteins: the Ca(2+) connection in dopamine signaling. , 2003, Trends in pharmacological sciences.

[335]  D. Comas,et al.  Association study between Alzheimer’s disease and genes involved in Aβ biosynthesis, aggregation and degradation: suggestive results with BACE1 , 2003, Journal of Neurology.

[336]  E. Fombonne Epidemiological Surveys of Autism and Other Pervasive Developmental Disorders: An Update , 2003, Journal of autism and developmental disorders.

[337]  Hongkui Zeng,et al.  Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[338]  Susumu Tonegawa,et al.  Evidence for association of schizophrenia with genetic variation in the 8p21.3 gene, PPP3CC, encoding the calcineurin gamma subunit , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[339]  P. Visscher,et al.  Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. , 2003, American journal of human genetics.

[340]  Francis J McMahon,et al.  Genomewide linkage analyses of bipolar disorder: a new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative. , 2003, American journal of human genetics.

[341]  Leena Peltonen,et al.  Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. , 2003, American journal of human genetics.

[342]  J B Eells The control of dopamine neuron development, function and survival: insights from transgenic mice and the relevance to human disease. , 2003, Current medicinal chemistry.

[343]  J. Haines,et al.  Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson’s disease , 2003, Neurology.

[344]  H. Ujike,et al.  The human dihydropyrimidinase-related protein 2 gene on chromosome 8p21 is associated with paranoid-type schizophrenia , 2003, Biological Psychiatry.

[345]  Janice M. Fullerton,et al.  Linkage analysis of extremely discordant and concordant sibling pairs identifies quantitative-trait loci that influence variation in the human personality trait neuroticism. , 2003, American journal of human genetics.

[346]  D. Blackwood,et al.  Chromosomal abnormalities and mental illness , 2003, Molecular Psychiatry.

[347]  W. T. Hung,et al.  Strong association between N-acetyltransferase 2 genotype and PD in Hong Kong Chinese , 2003, Neurology.

[348]  R. Ebstein,et al.  Tridimensional personality questionnaire trait of harm avoidance (anxiety proneness) is linked to a locus on chromosome 8p21 , 2003, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[349]  R. Lupu,et al.  Blockage of heregulin expression inhibits tumorigenicity and metastasis of breast cancer , 2003, Oncogene.

[350]  E. Lander,et al.  Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease , 2003, Nature Genetics.

[351]  J. Couzin Small RNAs Make Big Splash , 2002, Science.

[352]  F. Wright,et al.  Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53 , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[353]  Jeremy Nathans,et al.  Frizzled-3 Is Required for the Development of Major Fiber Tracts in the Rostral CNS , 2002, The Journal of Neuroscience.

[354]  Nelson B Freimer,et al.  Genomewide linkage disequilibrium mapping of severe bipolar disorder in a population isolate. , 2002, American journal of human genetics.

[355]  G. Rebeck,et al.  Lack of association of two lipoprotein lipase polymorphisms with Alzheimer's disease , 2002, Neuroscience Letters.

[356]  C. Verney,et al.  Changing distribution of monoaminergic markers in the developing human cerebral cortex with special emphasis on the serotonin transporter , 2002, The Anatomical record.

[357]  R. Petersen,et al.  No association between the lipoprotein lipase S447X polymorphism and Alzheimer's disease , 2002, Neuroscience Letters.

[358]  A. Meyer-Lindenberg,et al.  Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia , 2002, Nature Neuroscience.

[359]  J. Lotem,et al.  NQO1 stabilizes p53 through a distinct pathway , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[360]  D. Sidransky,et al.  Quantitative adenomatous polyposis coli promoter methylation analysis in tumor tissue, serum, and plasma DNA of patients with lung cancer. , 2002, Cancer research.

[361]  Emil Kraepelin,et al.  Dementia praecox and paraphrenia , 2002 .

[362]  R. Straub,et al.  Genome-wide scans of three independent sets of 90 Irish multiplex schizophrenia families and follow-up of selected regions in all families provides evidence for multiple susceptibility genes , 2002, Molecular Psychiatry.

[363]  J. McGrath,et al.  Genetic heterogeneity in schizophrenia II: conditional analyses of affected schizophrenia sibling pairs provide evidence for an interaction between markers on chromosome 8p and 14q , 2002, Molecular Psychiatry.

[364]  E. Gershon,et al.  Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia , 2002, Molecular Psychiatry.

[365]  K. Honczarenko,et al.  N-acetyltransferase 2 polymorphism in sporadic Parkinson's disease in a Polish population , 2002, European Journal of Clinical Pharmacology.

[366]  S. Tsai,et al.  Association study of the p53-gene Pro72Arg polymorphism in schizophrenia , 2001, Psychiatry Research.

[367]  M P Baur,et al.  A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q. , 2001, Human molecular genetics.

[368]  Hongkui Zeng,et al.  Forebrain-Specific Calcineurin Knockout Selectively Impairs Bidirectional Synaptic Plasticity and Working/Episodic-like Memory , 2001, Cell.

[369]  J. Haines,et al.  Complete genomic screen in Parkinson disease: evidence for multiple genes. , 2001, JAMA.

[370]  C. Dion,et al.  A search for specific and common susceptibility loci for schizophrenia and bipolar disorder: a linkage study in 13 target chromosomes , 2001, Molecular Psychiatry.

[371]  M. Deardorff,et al.  A role for frizzled 3 in neural crest development. , 2001, Development.

[372]  J. Thome,et al.  Potential genetic markers of sporadic Alzheimer's dementia , 2001, Psychiatric genetics.

[373]  M. Rugge,et al.  Fez1/lzts1 alterations in gastric carcinoma. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[374]  A. Jablensky,et al.  Schizophrenia and cancer: is there a need to invoke a protective gene? , 2001, Archives of general psychiatry.

[375]  David Curtis,et al.  Genetic association studies of schizophrenia using the 8p21-22 genes: prepronociceptin (PNOC), neuronal nicotinic cholinergic receptor alpha polypeptide 2 (CHRNA2) and arylamine N-acetyltransferase 1 (NAT1) , 2001, European Journal of Human Genetics.

[376]  A. Tanskanen,et al.  Incidence of cancer among persons with schizophrenia and their relatives. , 2001, Archives of general psychiatry.

[377]  G Kalsi,et al.  Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23. , 2001, American journal of human genetics.

[378]  M. Daly,et al.  A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms , 2001, Nature.

[379]  G. Lubec,et al.  Aberrant expression of dihydropyrimidinase related proteins-2,-3 and -4 in fetal Down syndrome brain. , 2001, Journal of neural transmission. Supplementum.

[380]  S. Tsai,et al.  A study of alpha-adrenoceptor gene polymorphisms and Alzheimer disease , 2001, Journal of Neural Transmission.

[381]  J. Knauber,et al.  Decreased exploratory activity and impaired passive avoidance behaviour in mice deficient for the α1b-adrenoceptor , 2000, European Neuropsychopharmacology.

[382]  T. Akiyama Wnt/beta-catenin signaling. , 2000, Cytokine & growth factor reviews.

[383]  R. Sulkava,et al.  Cardiovascular risk factors and Alzheimer's disease: a genetic association study in a population aged 85 or over , 2000, Neuroscience Letters.

[384]  H. Wiebusch,et al.  Roles for lipoprotein lipase in Alzheimer's disease: An association study , 2000, Microscopy research and technique.

[385]  Chao-Cheng Lin,et al.  No Evidence for Association of Alpha 1a Adrenoceptor Gene Polymorphism and Clozapine-Induced Urinary Incontinence , 2000, Neuropsychobiology.

[386]  D. Schaid,et al.  Case‐control study of debrisoquine 4‐hydroxylase, n‐acetyltransferase 2, and apolipoprotein e gene polymorphisms in Parkinson's disease , 2000, Movement disorders : official journal of the Movement Disorder Society.

[387]  S. Catts,et al.  Apoptosis and schizophrenia: is the tumour suppressor gene, p53, a candidate susceptibility gene? , 2000, Schizophrenia Research.

[388]  R. Kerwin,et al.  No influence of adrenergic receptor polymorphisms on schizophrenia and antipsychotic response , 2000, Neuroscience Letters.

[389]  C. Marsden,et al.  Detailed genotyping demonstrates association between the slow acetylator genotype for N‐Acetyltransferase 2 (NAT2) and familial parkinson's disease , 2000, Movement disorders : official journal of the Movement Disorder Society.

[390]  M. Hollstein,et al.  p53 and human cancer: the first ten thousand mutations. , 2000, Advances in cancer research.

[391]  K. Ressler,et al.  Role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders , 2000, Depression and anxiety.

[392]  R. Faull,et al.  Comparative proteome analysis of the hippocampus implicates chromosome 6q in schizophrenia , 2000, Molecular Psychiatry.

[393]  R. Yolken,et al.  Disease-specific alterations in frontal cortex brain proteins in schizophrenia, bipolar disorder, and major depressive disorder , 2000, Molecular Psychiatry.

[394]  K. Davis,et al.  The role of norepinephrine in the pathophysiology of cognitive disorders: potential applications to the treatment of cognitive dysfunction in schizophrenia and Alzheimer's disease , 1999, Biological Psychiatry.

[395]  R. Marconi,et al.  A study of five candidate genes in Parkinson's disease and related neurodegenerative disorders. European Study Group on Atypical Parkinsonism. , 1999, Neurology.

[396]  W. Honer,et al.  Linkage of familial schizophrenia to chromosome 13q32. , 1999, American journal of human genetics.

[397]  H. Zoghbi,et al.  Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2 , 1999, Nature Genetics.

[398]  A. Hofman,et al.  N-acetyltransferase-2 polymorphism in Parkinson’s disease: the Rotterdam study , 1999, Journal of neurology, neurosurgery, and psychiatry.

[399]  J. Dupret,et al.  Acetylator genotype for N‐acetyltransferase 2 and Parkinson's disease , 1999, Annals of neurology.

[400]  C. Pang,et al.  Lipoprotein lipase mutations and Alzheimer's disease. , 1999, American journal of medical genetics.

[401]  R. Straub,et al.  Marker-to-marker linkage disequilibrium on chromosomes 5q, 6p, and 8p in Irish high-density schizophrenia pedigrees. , 1999, American journal of medical genetics.

[402]  D. Bishop,et al.  N-acetyltransferase (NAT2) genotype and susceptibility of sporadic Alzheimer's disease. , 1999, Pharmacogenetics.

[403]  N. Cairns,et al.  Expression of the dihydropyrimidinase related protein 2 (DRP-2) in Down syndrome and Alzheimer's disease brain is downregulated at the mRNA and dysregulated at the protein level. , 1999, Journal of neural transmission. Supplementum.

[404]  F. Jiménez-Jiménez,et al.  Slow allotypic variants of the NAT2 gene and susceptibility to early-onset Parkinson's disease , 1998, Neurology.

[405]  J D Terwilliger,et al.  Linkage analysis of putative schizophrenia gene candidate regions on chromosomes 3p, 5q, 6p, 8p, 20p and 22q in a population-based sampled Finnish family set , 1998, Molecular Psychiatry.

[406]  C. Stefanis,et al.  Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21 , 1998, Nature Genetics.

[407]  J Blangero,et al.  Anxiety proneness linked to epistatic loci in genome scan of human personality traits. , 1998, American journal of medical genetics.

[408]  T. Matise,et al.  NIMH Genetics Initiative Millenium Schizophrenia Consortium: linkage analysis of African-American pedigrees. , 1998, American journal of medical genetics.

[409]  J. Costentin,et al.  Transient expression of the vesicular monoamine transporter during development in the rat thalamus and cortex , 1998, Neuroscience Letters.

[410]  M A Geyer,et al.  Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia. , 1998, Schizophrenia bulletin.

[411]  P. Worley,et al.  Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin. , 1997, Human molecular genetics.

[412]  C. Marsden,et al.  Association of slow acetylator genotype for N-acetyltransferase 2 with familial Parkinson's disease , 1997, The Lancet.

[413]  R. D. De Abreu,et al.  Dihydropyrimidinase deficiency, a progressive neurological disorder? , 1997, Neuropediatrics.

[414]  R. Straub,et al.  Evidence for a schizophrenia vulnerability locus on chromosome 8p in the Irish Study of High-Density Schizophrenia Families. , 1996, The American journal of psychiatry.

[415]  P. Goldman-Rakic The prefrontal landscape: implications of functional architecture for understanding human mentation and the central executive. , 1996, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[416]  J. Weissenbach,et al.  Genetic and physical mapping of the progressive epilepsy with mental retardation (EPMR) locus on chromosome 8p. , 1996, Genome research.

[417]  K. Kendler Seminars in Psychiatric Genetics , 1996 .

[418]  W. Dobyns,et al.  Absence makes the search grow longer. , 1996, American journal of human genetics.

[419]  J. Ott,et al.  Schizophrenia: a genome scan targets chromosomes 3p and 8p as potential sites of susceptibility genes. , 1995, American journal of medical genetics.

[420]  J. Weissenbach,et al.  The gene for a recessively inherited human childhood progressive epilepsy with mental retardation maps to the distal short arm of chromosome 8. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[421]  F. Happé An advanced test of theory of mind: Understanding of story characters' thoughts and feelings by able autistic, mentally handicapped, and normal children and adults , 1994, Journal of autism and developmental disorders.

[422]  A. Ogunniyi,et al.  Xenobiotic metabolism in idiopathic Parkinson's disease in Nigerian Africans. , 1993, East African medical journal.

[423]  F. Jiménez-Jiménez,et al.  Acetylator polymorphism in Alzheimer's disease. , 1993, The European journal of medicine.

[424]  M. Cowen,et al.  The Kallmann's syndrome variant (KSV) model of the schizophrenias , 1993, Schizophrenia Research.

[425]  B. Vogelstein,et al.  p53 mutations in human cancers. , 1991, Science.

[426]  B. Leventhal,et al.  Autism and tuberous sclerosis , 1991, Journal of autism and developmental disorders.

[427]  P. Rothberg,et al.  Oncogenes and cancer. , 1983, Cancer investigation.

[428]  F. J. Kallmann,et al.  Heredity and eugenics. , 1963, The American journal of psychiatry.

[429]  Fj Kallmann The genetic aspects of primary eunuchoidism , 1944 .