Development of gellan gum containing formulations for transdermal drug delivery: Component evaluation and controlled drug release using temperature responsive nanogels.

[1]  A. Kelemen,et al.  Investigation of the Efficacy of Transdermal Penetration Enhancers Through the Use of Human Skin and a Skin Mimic Artificial Membrane. , 2016, Journal of pharmaceutical sciences.

[2]  Monika Brzychczy-Wloch,et al.  Injectable gellan gum-based nanoparticles-loaded system for the local delivery of vancomycin in osteomyelitis treatment , 2015, Journal of Materials Science: Materials in Medicine.

[3]  Gary P. Moss,et al.  Predictive Methods in Percutaneous Absorption , 2015, Springer Berlin Heidelberg.

[4]  M. Patil,et al.  Formulation development, in vitro and in vivo evaluation of microemulsion-based gel loaded with ketoprofen , 2015, Drug delivery.

[5]  N. Škalko-Basnet,et al.  Phospholipid vesicle-based permeation assay and EpiSkin® in assessment of drug therapies destined for skin administration. , 2015, Journal of pharmaceutical sciences.

[6]  K. Sugibayashi,et al.  Prediction of skin permeation by chemical compounds using the artificial membrane, Strat-M™. , 2015, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[7]  C. Moseke,et al.  Reaction kinetics of dual setting α-tricalcium phosphate cements , 2015, Journal of Materials Science: Materials in Medicine.

[8]  M. Lane,et al.  Formulation of diclofenac for dermal delivery. , 2014, International journal of pharmaceutics.

[9]  A. Froelich,et al.  Application of gellan gum in pharmacy and medicine. , 2014, International journal of pharmaceutics.

[10]  Ryan M. Pearson,et al.  Dendron‐Based Micelles for Topical Delivery of Endoxifen: A Potential Chemo‐Preventive Medicine for Breast Cancer , 2014 .

[11]  M. H. Zulfakar,et al.  Recent advances in gel technologies for topical and transdermal drug delivery , 2014, Drug development and industrial pharmacy.

[12]  S. Mazzitelli,et al.  Hydrogel blends with adjustable properties as patches for transdermal delivery. , 2013, International journal of pharmaceutics.

[13]  P. Paolicelli,et al.  Spermidine-cross-linked hydrogels as novel potential platforms for pharmaceutical applications. , 2013, Journal of pharmaceutical sciences.

[14]  S. Stanos,et al.  Topical Therapies in the Management of Chronic Pain , 2013, Postgraduate medicine.

[15]  J. Sousa,et al.  Co-encapsulating nanostructured lipid carriers for transdermal application: from experimental design to the molecular detail. , 2013, Journal of controlled release : official journal of the Controlled Release Society.

[16]  Majella E Lane,et al.  Skin penetration enhancers. , 2013, International journal of pharmaceutics.

[17]  D. Capitani,et al.  Self-assembled gellan-based nanohydrogels as a tool for prednisolone delivery , 2012 .

[18]  C. Paterson,et al.  Skin permeability and pharmacokinetics of diclofenac epolamine administered by dermal patch in Yorkshire-Landrace pigs , 2012, Journal of Pain Research.

[19]  M. Basri,et al.  Modification of palm kernel oil esters nanoemulsions with hydrocolloid gum for enhanced topical delivery of ibuprofen , 2012, International journal of nanomedicine.

[20]  V. Kozlovskaya,et al.  Thermosensitive multilayer hydrogels of poly(N-vinylcaprolactam) as nanothin films and shaped capsules. , 2012, Chemistry of materials : a publication of the American Chemical Society.

[21]  L. Misery,et al.  Adherence to topical treatment in psoriasis: a systematic literature review , 2012, Journal of the European Academy of Dermatology and Venereology : JEADV.

[22]  Bálint Sinkó,et al.  Skin-PAMPA: a new method for fast prediction of skin penetration. , 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[23]  R. Parhi,et al.  Novel penetration enhancers for skin applications: a review. , 2012, Current drug delivery.

[24]  P. Davis,et al.  Topical NSAIDs for Musculoskeletal Conditions , 1998, Drugs.

[25]  Lawrence X. Yu,et al.  Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing of Topical Dermatologic Products , 2012, The AAPS Journal.

[26]  Todd Hoare,et al.  Injectable microgel-hydrogel composites for prolonged small-molecule drug delivery. , 2011, Biomacromolecules.

[27]  Karrie Marren.  Dimethyl Sulfoxide: An Effective Penetration Enhancer for Topical Administration of NSAIDs , 2011, The Physician and sportsmedicine.

[28]  M. S. Kallos,et al.  Optimizing gelling parameters of gellan gum for fibrocartilage tissue engineering. , 2011, Journal of biomedical materials research. Part B, Applied biomaterials.

[29]  J. Forcada,et al.  Synthesis strategies to incorporate acrylic acid into N-vinylcaprolactam-based microgels† , 2011 .

[30]  P. Claesson,et al.  Investigation of the formation, structure and release characteristics of self-assembled composite films of cellulose nanofibrils and temperature responsive microgels , 2011 .

[31]  Peter Lindner,et al.  Composite hydrogels with temperature sensitive heterogeneities: influence of gel matrix on the volume phase transition of embedded poly-(N-isopropylacrylamide) microgels. , 2011, Physical chemistry chemical physics : PCCP.

[32]  A. Singer,et al.  Topical drug delivery by a polymeric nanosphere gel: Formulation optimization and in vitro and in vivo skin distribution studies. , 2011, Journal of controlled release : official journal of the Controlled Release Society.

[33]  L. Jorge,et al.  Topical preparations for pain relief: efficacy and patient adherence , 2010, Journal of pain research.

[34]  Ming-Wei Lee,et al.  Preparation, characterization and biological properties of Gellan gum films with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide cross-linker , 2010 .

[35]  V. Meidan,et al.  Validation of a Static Franz Diffusion Cell System for In Vitro Permeation Studies , 2010, AAPS PharmSciTech.

[36]  Xiaoling Li,et al.  Semisolid Dosages: Ointments, Creams, and Gels , 2010 .

[37]  C. Asbill,et al.  Transdermal Drug Delivery , 2010 .

[38]  M. Gold,et al.  Systemic Bioavailability of Topical Diclofenac Sodium Gel 1% Versus Oral Diclofenac Sodium in Healthy Volunteers , 2010, Journal of clinical pharmacology.

[39]  R. K. Sharma,et al.  TRANSDERMAL DRUG DELIVERY , 2010 .

[40]  G. Nath,et al.  Preparation and in vitro antibacterial evaluation of gatifloxacin mucoadhesive gellan system , 2010, Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences.

[41]  T. Coviello,et al.  Preparation and Characterization of Novel Gellan Gum Hydrogels Suitable for Modified Drug Release , 2009, Molecules.

[42]  D. Barends,et al.  Biowaiver monographs for immediate release solid oral dosage forms: diclofenac sodium and diclofenac potassium. , 2009, Journal of pharmaceutical sciences.

[43]  Puchun Liu,et al.  Effects of isopropanol-isopropyl myristate binary enhancers on in vitro transport of estradiol in human epidermis: a mechanistic evaluation. , 2009, Journal of pharmaceutical sciences.

[44]  Daniel J. Thompson,et al.  Transdermal hormone therapy in postmenopausal women: A review of metabolic effects and drug delivery technologies , 2008, Drug design, development and therapy.

[45]  Patrick J. Schexnailder,et al.  Nanocomposite polymer hydrogels , 2009 .

[46]  A. Shiras,et al.  Natural gum reduced/stabilized gold nanoparticles for drug delivery formulations. , 2008, Chemistry.

[47]  B. Conway,et al.  Penetration of Chlorhexidine into Human Skin , 2008, Antimicrobial Agents and Chemotherapy.

[48]  Işık Özgüney,et al.  Transdermal delivery of diclofenac sodium through rat skin from various formulations , 2006, AAPS PharmSciTech.

[49]  L. Rizza,et al.  Evaluation of alternative strategies to optimize ketorolac transdermal delivery , 2006, AAPS PharmSciTech.

[50]  Y. Kalia,et al.  In vitro and in vivo evaluation of the transdermal iontophoretic delivery of sumatriptan succinate. , 2007, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[51]  J. F. Jiménez,et al.  Topical ketoprofen TDS patch versus diclofenac gel: efficacy and tolerability in benign sport related soft-tissue injuries , 2006, British Journal of Sports Medicine.

[52]  A. Metters,et al.  Hydrogels in controlled release formulations: network design and mathematical modeling. , 2006, Advanced drug delivery reviews.

[53]  P. Srivastava.  Excipients for Semisolid Formulations , 2006 .

[54]  Hongzhuo Liu,et al.  Effect of vehicles and enhancers on the topical delivery of cyclosporin A. , 2006, International journal of pharmaceutics.

[55]  Chih-Chang Chu,et al.  Fabrication and characterization of a smart drug delivery system: microsphere in hydrogel. , 2005, Biomaterials.

[56]  U. Akarca.  Gastrointestinal effects of selective and non-selective non-steroidal anti-inflammatory drugs. , 2005, Current pharmaceutical design.

[57]  K. Dawson,et al.  Simultaneous release of hydrophobic and cationic solutes from thin-film "plum-pudding" gels: a multifunctional platform for surface drug delivery? , 2005, The journal of physical chemistry. B.

[58]  S. Scheindlin.  Transdermal drug delivery: PAST, PRESENT, FUTURE. , 2004, Molecular interventions.

[59]  B. Tashtoush,et al.  Azathioprine transport through rat skin and its immunosuppressive effect. , 2004, Die Pharmazie.

[60]  S. Güngör,et al.  Effect of penetration enhancers on in vitro percutaneous penetration of nimesulide through rat skin. , 2004, Die Pharmazie.

[61]  Adrian C. Williams,et al.  Penetration enhancers. , 2004, Advanced drug delivery reviews.

[62]  S. Baumgartner,et al.  Network Structure of Cellulose Ethers Used in Pharmaceutical Applications During Swelling and at Equilibrium , 2004, Pharmaceutical Research.

[63]  Martin Grosell,et al.  Biochimica et Biophysica Acta (BBA)/Biomembranes: Preface , 2003 .

[64]  J. Marty,et al.  Characterization of the barrier function in a reconstituted human epidermis cultivated in chemically defined medium , 2002, International journal of cosmetic science.

[65]  G. Cevc,et al.  New, highly efficient formulation of diclofenac for the topical, transdermal administration in ultradeformable drug carriers, Transfersomes. , 2001, Biochimica et biophysica acta.

[66]  J. Cramer,et al.  A systematic review of the associations between dose regimens and medication compliance. , 2001, Clinical therapeutics.

[67]  G. Wall,et al.  Oral versus topical NSAIDs in rheumatic diseases: a comparison. , 2000, Drugs.

[68]  S. Santoyo,et al.  Influence of propylene glycol and isopropyl myristate on the in vitro percutaneous penetration of diclofenac sodium from carbopol gels. , 1999, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[69]  R. Bucci,et al.  Determination of diclofenac salts in pharmaceutical formulations , 1998 .

[70]  H. Eichler,et al.  Diclofenac concentrations in defined tissue layers after topical administration , 1997, Clinical pharmacology and therapeutics.

[71]  J. Domenech,et al.  A comparative study of the transdermal penetration of a series of nonsteroidal antiinflammatory drugs. , 1997, Journal of pharmaceutical sciences.

[72]  M. Carafa,et al.  Gellan in sustained release formulations: preparation of gel capsules and release studies. , 1996, Biomaterials.

[73]  R. Neubert,et al.  Influence of propylene glycol as cosolvent on mechanisms of drug transport from hydrogels , 1995 .

[74]  D. Friedman,et al.  Submicron emulsion vehicle for enhanced transdermal delivery of steroidal and nonsteroidal antiinflammatory drugs. , 1995, Journal of pharmaceutical sciences.

[75]  H O Ho,et al.  The Influence of Cosolvents on the In‐vitro Percutaneous Penetration of Diclofenac Sodium From a Gel System , 1994, The Journal of pharmacy and pharmacology.

[76]  M. Roberts,et al.  Skin permeability and local tissue concentrations of nonsteroidal anti-inflammatory drugs after topical application. , 1994, The Journal of pharmacology and experimental therapeutics.

[77]  T. Zimmerman,et al.  A Double‐Masked, Placebo‐Controlled Evaluation of Timolol in a Gel Vehicle , 1993, Journal of glaucoma.

[78]  J. H. Rytting,et al.  In vitro percutaneous transport of sodium diclofenac and diclofenac from oleaginous vehicle. , 1991, Chemical & pharmaceutical bulletin.

[79]  H. Junginger,et al.  Hydrogel Patches for Transdermal Drug Delivery; In‐vivo Water Exchange and Skin Compatibility , 1989, The Journal of pharmacy and pharmacology.

[80]  P. A. Todd,et al.  Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. , 1988, Drugs.

[81]  A Ward,et al.  Pentoxifylline , 1987, Drugs.

[82]  Nicholas A. Peppas,et al.  A simple equation for description of solute release I. Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs , 1987 .

[83]  J. Zatz,et al.  Evaluation of penetration enhancement of lidocaine by nonionic surfactants through hairless mouse skin in vitro. , 1986, Journal of pharmaceutical sciences.

[84]  C. Gordon Arman,et al.  Anti-Inflammatory Drugs , 1979, Handbook of Experimental Pharmacology.

[85]  W. Higuchi,et al.  Analysis of data on the medicament release from ointments. , 1962, Journal of pharmaceutical sciences.