Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function

[1]  B. Christ,et al.  Cytokinetic studies on the aortic endothelium and limb bud vascularization in avian embryos , 1992, Anatomy and Embryology.

[2]  A. Kolodkin,et al.  Semaphorin junction: making tracks toward neural connectivity , 2003, Current Opinion in Neurobiology.

[3]  Richard O Hynes,et al.  Integrins Bidirectional, Allosteric Signaling Machines , 2002, Cell.

[4]  K. Kullander,et al.  Mechanisms and functions of eph and ephrin signalling , 2002, Nature Reviews Molecular Cell Biology.

[5]  D. Davidson,et al.  Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. , 2002, Arteriosclerosis, thrombosis, and vascular biology.

[6]  C. Tse,et al.  Semaphorin 3F gene from human 3p21.3 suppresses tumor formation in nude mice. , 2002, Cancer research.

[7]  R. Klemke,et al.  Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold , 2002, The Journal of cell biology.

[8]  Dwayne G Stupack,et al.  ECM Remodeling Regulates Angiogenesis: Endothelial Integrins Look for New Ligands , 2002, Science's STKE.

[9]  C. Tse,et al.  Human Semaphorin 3B (SEMA3B) located at chromosome 3p21.3 suppresses tumor formation in an adenocarcinoma cell line. , 2002, Cancer research.

[10]  P. Robson,et al.  The Role of Cell Adhesion Receptors in Vascular Development: An Overview , 2002 .

[11]  G. Neufeld,et al.  The neuropilins: multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis. , 2002, Trends in cardiovascular medicine.

[12]  R. Tomanek.  Assembly of the Vasculature and Its Regulation , 2002, Cardiovascular Molecular Morphogenesis.

[13]  Kenneth M. Yamada,et al.  Transmembrane crosstalk between the extracellular matrix and the cytoskeleton , 2001, Nature Reviews Molecular Cell Biology.

[14]  David A. Cheresh,et al.  Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins , 2001, The Journal of cell biology.

[15]  Shu Chien,et al.  Activation of integrins in endothelial cells by fluid shear stress mediates Rho‐dependent cytoskeletal alignment , 2001, The EMBO journal.

[16]  J. Epstein,et al.  Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch interruption. , 2001, Development.

[17]  J. Epstein,et al.  PlexinA2 and semaphorin signaling during cardiac neural crest development. , 2001, Development.

[18]  K. Beningo,et al.  Nascent Focal Adhesions Are Responsible for the Generation of Strong Propulsive Forces in Migrating Fibroblasts , 2001, The Journal of cell biology.

[19]  M. Schwartz,et al.  Rac recruits high-affinity integrin αvβ3 to lamellipodia in endothelial cell migration , 2001, Nature Cell Biology.

[20]  M. Poo,et al.  Plexins Are a Large Family of Receptors for Transmembrane, Secreted, and GPI-Anchored Semaphorins in Vertebrates , 1999, Cell.

[21]  T. Byzova,et al.  A mechanism for modulation of cellular responses to VEGF: activation of the integrins. , 2000, Molecular cell.

[22]  Stanley J. Wiegand,et al.  Vascular-specific growth factors and blood vessel formation , 2000, Nature.

[23]  F. Bussolino,et al.  Human endothelial cells expressing polyoma middle T induce tumors , 2000, Oncogene.

[24]  C. Sigmund.  Viewpoint: are studies in genetically altered mice out of control? , 2000, Arteriosclerosis, thrombosis, and vascular biology.

[25]  Semi Kim,et al.  Regulation of Angiogenesis in Vivo by Ligation of Integrin α5β1 with the Central Cell-Binding Domain of Fibronectin , 2000 .

[26]  M. Kinch,et al.  Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation , 2000, Nature Cell Biology.

[27]  T. Yagi,et al.  A requirement for neuropilin-1 in embryonic vessel formation. , 1999, Development.

[28]  G. Nemerow,et al.  Mechanisms and Consequences of Affinity Modulation of Integrin αVβ3 Detected with a Novel Patch-engineered Monovalent Ligand* , 1999, The Journal of Biological Chemistry.

[29]  Kenneth M. Yamada,et al.  Shc and Fak Differentially Regulate Cell Motility and Directionality Modulated by Pten , 1999, The Journal of cell biology.

[30]  S. Soker,et al.  Neuropilin-1 Mediates Collapsin-1/Semaphorin III Inhibition of Endothelial Cell Motility , 1999, The Journal of cell biology.

[31]  F. Diella,et al.  Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. , 1999, Genes & development.

[32]  R. Hynes,et al.  Extensive Vasculogenesis, Angiogenesis, and Organogenesis Precede Lethality in Mice Lacking All αv Integrins , 1998, Cell.

[33]  R J Read,et al.  Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.

[34]  L. Trusolino,et al.  Growth Factor–dependent Activation of αvβ3 Integrin in Normal Epithelial Cells: Implications for Tumor Invasion , 1998, The Journal of cell biology.

[35]  M. Martín-Bermudo,et al.  Modulation of Integrin Activity is Vital for Morphogenesis , 1998, The Journal of cell biology.

[36]  C. Tabin,et al.  Targeted gene misexpression in chick limb buds using avian replication-competent retroviruses. , 1998, Methods.

[37]  G P Nolan,et al.  High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein. , 1998, Cancer research.

[38]  C. Dalgard,et al.  Functional partitioning of beta1 integrins revealed by activating and inhibitory mAbs. , 1997, Journal of cell science.

[39]  R. Timpl,et al.  Properties of the extracellular calcium binding module of the proteoglycan testican , 1997, FEBS letters.

[40]  T. Yagi,et al.  Disruption of Semaphorin III/D Gene Causes Severe Abnormality in Peripheral Nerve Projection , 1997, Neuron.

[41]  CeciliaGarlanda,et al.  Heterogeneity of Endothelial Cells , 1997 .

[42]  C. Garlanda,et al.  Heterogeneity of endothelial cells. Specific markers. , 1997, Arteriosclerosis, thrombosis, and vascular biology.

[43]  Z. Otwinowski,et al.  Processing of X-ray diffraction data collected in oscillation mode. , 1997, Methods in enzymology.

[44]  Jeffrey A. Golden,et al.  Semaphorin III is needed for normal patterning and growth of nerves, bones and heart , 1996, Nature.

[45]  D. Lauffenburger,et al.  Cell Migration: A Physically Integrated Molecular Process , 1996, Cell.

[46]  David A. Cheresh,et al.  Definition of Two Angiogenic Pathways by Distinct αv Integrins , 1995, Science.

[47]  F. Sarkar,et al.  Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin. , 1995, The Journal of clinical investigation.

[48]  D. Cheresh,et al.  Integrin α v β 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels , 1994, Cell.

[49]  D. Cheresh,et al.  Requirement of vascular integrin alpha v beta 3 for angiogenesis. , 1994, Science.

[50]  J. Navaza,et al.  AMoRe: an automated package for molecular replacement , 1994 .

[51]  T. Blundell,et al.  Comparative protein modelling by satisfaction of spatial restraints. , 1993, Journal of molecular biology.

[52]  R. Hynes,et al.  Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. , 1993, Development.

[53]  V. Hamburger,et al.  A series of normal stages in the development of the chick embryo. 1951. , 2012, Developmental dynamics : an official publication of the American Association of Anatomists.

[54]  L. Reichardt,et al.  Cell-surface regulation of β1-integrin activity on developing retinal neurons , 1991, Nature.

[55]  Viktor Hamburger,et al.  A series of normal stages in the development of the chick embryo , 1992, Journal of morphology.

[56]  H. Evans.  On the development of the aortae, cardinal and umbilical veins, and the other blood vessels of vertebrate embryos from capillaries , 1909 .