Characterization and limitations of diffusion tensor imaging metrics in the cervical spinal cord in neurologically intact subjects

To characterize diffusion tensor imaging (DTI) metrics across all levels of the cervical spinal cord (CSC) and to study the impact of age and signal quality on these metrics.

[1]  Craig K. Jones,et al.  Reproducibility of tract‐specific magnetization transfer and diffusion tensor imaging in the cervical spinal cord at 3 tesla , 2009, NMR in biomedicine.

[2]  Ferenc A. Jolesz,et al.  Collateral nerve fibers in human spinal cord: Visualization with magnetic resonance diffusion tensor imaging , 2006, NeuroImage.

[3]  A. A. Bailey.  Changes with age in the spinal cord. , 1953, A.M.A. archives of neurology and psychiatry.

[4]  P. Boesiger,et al.  Diffusion‐weighted imaging of the entire spinal cord , 2009, NMR in biomedicine.

[5]  S. Maier,et al.  Apparent diffusion coefficient and fractional anisotropy in spinal cord: Age and cervical spondylosis–related changes , 2005, Journal of magnetic resonance imaging : JMRI.

[6]  Derek K. Jones,et al.  “Squashing peanuts and smashing pumpkins”: How noise distorts diffusion‐weighted MR data , 2004, Magnetic resonance in medicine.

[7]  H. Gudbjartsson,et al.  The rician distribution of noisy mri data , 1995, Magnetic resonance in medicine.

[8]  G. Sobue,et al.  Age-related changes in human spinal ventral horn cells with special reference to the loss of small neurons in the intermediate zone: a quantitative analysis , 1996, Acta Neuropathologica.

[9]  E. D. Schwartz,et al.  In vivo DTI evaluation of white matter tracts in rat spinal cord , 2006, Journal of magnetic resonance imaging : JMRI.

[10]  K J Klose,et al.  High-resolution diffusion-weighted MR of fresh and fixed cat spinal cords: evaluation of diffusion coefficients and anisotropy. , 1997, AJNR. American journal of neuroradiology.

[11]  K. Hasan,et al.  Diffusion tensor imaging of in vivo and excised rat spinal cord at 7 T with an icosahedral encoding scheme , 2005, Magnetic resonance in medicine.

[12]  Petros Martirosian,et al.  Water diffusion anisotropy in white and gray matter of the human spinal cord , 2008, Journal of magnetic resonance imaging : JMRI.

[13]  Gareth J. Barker,et al.  Investigating Cervical Spinal Cord Structure Using Axial Diffusion Tensor Imaging , 2002, NeuroImage.

[14]  J. Cohen‐Adad,et al.  Human cervical spinal cord funiculi: Investigation with magnetic resonance diffusion tensor imaging , 2010, Journal of magnetic resonance imaging : JMRI.

[15]  S. Maier,et al.  Characterization of central nervous system structures by magnetic resonance diffusion anisotropy , 2004, Neurochemistry International.

[16]  B D Schmit,et al.  Diffusion Tensor MR Imaging of the Neurologically Intact Human Spinal Cord , 2008, American Journal of Neuroradiology.

[17]  R. Stollberger,et al.  Diffusion-weighted MR imaging of the spinal cord. , 2000, AJNR. American journal of neuroradiology.

[18]  Diffusion-weighted echo planar imaging of the normal human cervical spinal cord. , 2000, Journal of computer assisted tomography.

[19]  P. Basser,et al.  Toward a quantitative assessment of diffusion anisotropy , 1996, Magnetic resonance in medicine.

[20]  A. Wright,et al.  Magnetic resonance microimaging of intraaxonal water diffusion in live excised lamprey spinal cord , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[21]  Gen Sobue,et al.  Age-related changes of the myelinated fibers in the human corticospinal tract: a quantitative analysis , 2004, Acta Neuropathologica.

[22]  P. Basser,et al.  MR diffusion tensor spectroscopy and imaging. , 1994, Biophysical journal.

[23]  C. Beaulieu,et al.  The basis of anisotropic water diffusion in the nervous system – a technical review , 2002, NMR in biomedicine.

[24]  C T Moonen,et al.  Diffusion tensor MRI of the spinal cord , 2000, Magnetic resonance in medicine.

[25]  M. Horsfield,et al.  Sensitivity-encoded diffusion tensor MR imaging of the cervical cord. , 2003, AJNR. American journal of neuroradiology.

[26]  M. Maier,et al.  White Matter Organization in Cervical Spinal Cord Relates Differently to Age and Control of Grip Force in Healthy Subjects , 2010, The Journal of Neuroscience.

[27]  C. Holder,et al.  Diffusion-weighted MR imaging of the normal human spinal cord in vivo. , 2000, AJNR. American journal of neuroradiology.

[28]  M. Bastin,et al.  A theoretical study of the effect of experimental noise on the measurement of anisotropy in diffusion imaging. , 1998, Magnetic resonance imaging.

[29]  F. F. Cruz-Sánchez,et al.  Evaluation of neuronal loss, astrocytosis and abnormalities of cytoskeletal components of large motor neurons in the human anterior horn in aging , 1998, Journal of Neural Transmission.

[30]  Y. Toyama,et al.  Changes of cervical spinal cord and cervical spinal canal with age in asymptomatic subjects , 2003, Spinal Cord.

[31]  U. Klose,et al.  Diffusion Tensor Imaging of the Spinal Cord at 1.5 and 3.0 Tesla , 2007, RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin.

[32]  B. Ellingson,et al.  Diffusion Tensor MR Imaging in Chronic Spinal Cord Injury , 2008, American Journal of Neuroradiology.

[33]  Naoki Ishiguro,et al.  Measurement of the Cervical Spinal Cord Volume on MRI , 2006, Journal of spinal disorders & techniques.

[34]  Daniel L. Polders,et al.  Signal to noise ratio and uncertainty in diffusion tensor imaging at 1.5, 3.0, and 7.0 Tesla , 2011, Journal of magnetic resonance imaging : JMRI.

[35]  P. Parizel,et al.  A tracking‐based diffusion tensor imaging segmentation method for the detection of diffusion‐related changes of the cervical spinal cord with aging , 2008, Journal of magnetic resonance imaging : JMRI.

[36]  Massimo Filippi,et al.  Evidence for cervical cord tissue disorganisation with aging by diffusion tensor MRI , 2007, NeuroImage.

[37]  Duan Xu,et al.  Single-shot fast spin-echo diffusion tensor imaging of the lumbar spine at 1.5 and 3 T. , 2007, Magnetic resonance imaging.

[38]  G. Barker,et al.  Magnetic resonance diffusion imaging of the human cervical spinal cord in vivo , 1999, Magnetic resonance in medicine.

[39]  D. Ortendahl,et al.  Measuring signal-to-noise ratios in MR imaging. , 1989, Radiology.