A study of certain characteristics of strontium metabolism in a homogeneous group of human subjects.

The results of the study of 85Sr metabolism in 44 healthy young men aged 23 f 2 yr are presented. During the 3-6 months after intravenous injection (eight human subjects) or oral administration (36 human subjects) of the label retention of 85Sr in the organisms was measured. During the 5-8 days following the administration the values of the complete s5Sr excretion were studied. The coefficient of absorption of 85Sr from the GI tract into the blood stream was estimated to be 28 =t 2.5. It was demonstrated that the data on 85Sr retention in the organism of normal young men for the time period of 3-6 months following the injection may be approximated by the following equation: R ( t ) = (0.79 f 0.05)t-(0.18k 0.04). The comparison of the results obtained in the present research with the data of other authors has been made.