A case-control study of lung cancer in nonsmoking women.

A case-control study of Japanese women in Nagoya was conducted to investigate the significance of passive smoking and other factors in relation to the etiology of female lung cancer. A total of 90 nonsmoking patients with primary lung cancer and their age- and hospital-matched female controls were asked to fill in a questionnaire in the hospital. Elevated relative risk (RR) of lung cancer was observed for passive smoking from mother (RR = 4.0; p less than 0.05) and from husband's father (RR = 3.2; p less than 0.05). No association was observed between the risk of lung cancer and smoking of husband or passive smoke exposure at work. Occupational exposure to iron or other metals also showed high risk (RR = 4.8; p less than 0.05). No appreciable differences in food intakes were observed between cases and controls.

[1]  B. Macmahon,et al.  Lung cancer and passive smoking , 1981, International journal of cancer.

[2]  J. Hankin,et al.  Dietary cholesterol and lung cancer risk in a multiethnic population in Hawaii , 1983, International journal of cancer.

[3]  W. Blot,et al.  Passive smoking and lung cancer among Japanese women. , 1986, Cancer research.

[4]  E. Wynder,et al.  Lung cancer in nonsmokers , 1984, Cancer.

[5]  N. Wald,et al.  URINARY COTININE AS MARKER OF BREATHING OTHER PEOPLE'S TOBACCO SMOKE , 1984, The Lancet.

[6]  N. Breslow,et al.  Estimation of multiple relative risk functions in matched case-control studies. , 1978, American journal of epidemiology.

[7]  T. Byers,et al.  The epidemiology of diet and cancer. , 1984, Advances in cancer research.

[8]  L. Garfinkel,et al.  Involuntary smoking and lung cancer: a case-control study. , 1985, Journal of the National Cancer Institute.

[9]  S. Matsukura,et al.  Effects of environmental tobacco smoke on urinary cotinine excretion in nonsmokers. Evidence for passive smoking. , 1984, The New England journal of medicine.

[10]  L. Kolonel,et al.  Dietary vitamin A, carotene, vitamin C and risk of lung cancer in Hawaii. , 1984, American journal of epidemiology.

[11]  S. Hisamichi,et al.  Risk of lung cancer by histologic type among smokers in Miyagi Prefecture. , 1986, Japanese journal of clinical oncology.

[12]  L. Garfinkel.  Time trends in lung cancer mortality among nonsmokers and a note on passive smoking. , 1981, Journal of the National Cancer Institute.

[13]  N. Breslow,et al.  The analysis of case-control studies , 1980 .

[14]  M. Matsuda,et al.  Relationship between smoking and the four major histologic types of lung cancer. , 1986 .

[15]  T. Hirayama.  Non-smoking wives of heavy smokers have a higher risk of lung cancer: a study from Japan. , 1981, British medical journal.

[16]  M. Finkelstein,et al.  Mortality among miners receiving workmen's compensation for silicosis in Ontario: 1940-1975. , 1982, Journal of occupational medicine. : official publication of the Industrial Medical Association.

[17]  P. Lee,et al.  Relationship of passive smoking to risk of lung cancer and other smoking-associated diseases. , 1986, British Journal of Cancer.

[18]  B. Henderson,et al.  Smoking and other risk factors for lung cancer in women. , 1985, Journal of the National Cancer Institute.

[19]  PASSIVE SMOKING AND LUNG CANCER , 1983, The Lancet.