Prevalence of type 1 diabetes mellitus in school children 6-18 years old in Diyarbakir, Southeastern Anatolian Region of Turkey

Materials and methods: The number of children with T1DM and the total number of children at the schools were defined in cooperation with the Diyarbakir Provincial Education Directorate. T1DM prevalence was calculated with the obtained data. Results: The number of school children 6-18 years old with T1DM in Diyarbakir was 176; and the total number of school children was 419,526. The prevalence of T1DM was found as 0.42/1000. Of the T1DM patients, 94 (53.4%) were female and 82 (46.6%) were male; the female-to-male ratio was 1.2/1. The prevalence of females (0.47/103) was higher than that of males (0.37/103). It was 0.47/103 in the city center of Diyarbakir, higher than that calculated in the other districts of the city (0.35/103). Conclusion: The defined prevalence of T1DM in school children 6-18 years old in Diyarbakir in the Southeastern Anatolian Region of Turkey is higher than the prevalence reported from Ankara in 1993 and is lower than the prevalence reported from Istanbul in 2009. Results indicated variability in T1DM frequency among regions of Turkey.

[1]  A. Green,et al.  Trends in the incidence of childhood-onset diabetes in Europe 1989–1998 , 2001, Diabetologia.

[2]  J. Tuomilehto,et al.  Worldwide increase in incidence of Type I diabetes – the analysis of the data on published incidence trends , 1999, Diabetologia.

[3]  Jaakko Tuomilehto,et al.  Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study , 2008, The Lancet.

[4]  A. Güler Morphological Characters of Some Important Races and Ecotypes of Turkish Honeybees (Apis mellifera L.)-II , 1999 .

[5]  Dokheel Tm An epidemic of childhood diabetes in the United States? Evidence from Allegheny County, Pennsylvania. Pittsburgh Diabetes Epidemiology Research Group. , 1993 .

[6]  O. Kaftanoğlu,et al.  Turkish honey bees belong to the east Mediterranean mitochondrial lineage , 1997 .

[7]  L. Nyström,et al.  The incidence of Type I diabetes has not increased but shifted to a younger age at diagnosis in the 0–34 years group in Sweden 1983 to 1998 , 2002, Diabetologia.

[8]  C. Beaufort Variation and trends in incidence of childhood diabetes in Europe , 2000, The Lancet.

[9]  Ayhan Cevik,et al.  Distribution of congenital heart disease in Turkey* , 2011, Turkish Journal of Medical Sciences.

[10]  E. Gale,et al.  Diabetes and gender , 2001, Diabetologia.

[11]  J. Stockman,et al.  Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005–20: a multicentre prospective registration study , 2011 .

[12]  Ozge Sarac,et al.  The prevalence of pterygium in Ankara: a hospital-based study , 2012, Turkish Journal of Medical Sciences.

[13]  J. Tuomilehto,et al.  The onset age of type 1 diabetes in Finnish children has become younger. The Finnish Childhood Diabetes Registry Group. , 1999, Diabetes care.

[14]  P. Czernichow,et al.  Incidence Data of Childhood-Onset Type I Diabetes in France During 1988–1997: The Case for a Shift Toward Younger Age at Onset , 2002, Pediatric Research.

[15]  T. Jones,et al.  Independent effects of socioeconomic status and place of residence on the incidence of childhood type 1 diabetes in Western Australia , 2006, Pediatric diabetes.

[16]  A. Kence,et al.  Genetic structure of honeybee, Apis mellifera L. (Hymenoptera: Apidae) populations of Turkey inferred from microsatellite analysis , 2007 .

[17]  M. Abdul-Rasoul,et al.  Incidence and seasonal variation of Type 1 diabetes in children in Farwania area, Kuwait (1995-1999). , 2002, Diabetes research and clinical practice.

[18]  J. Tuomilehto,et al.  Incidence of childhood type 1 diabetes worldwide. Diabetes Mondiale (DiaMond) Project Group. , 2000, Diabetes care.

[19]  F. Alexander,et al.  Small area variation in the incidence of childhood insulin-dependent diabetes mellitus in Yorkshire, UK: links with overcrowding and population density. , 1997, International journal of epidemiology.

[20]  F. Rohlf Shape Statistics: Procrustes Superimpositions and Tangent Spaces , 1999 .

[21]  Professor Dr. Friedrich Ruttner Biogeography and Taxonomy of Honeybees , 1987, Springer Berlin Heidelberg.

[22]  R. Lorini,et al.  Diabetes incidence in 0- to 14-year age-group in Italy: a 10-year prospective study. , 2004, Diabetes care.

[23]  A. Green,et al.  Geographical variation of presentation at diagnosis of Type I diabetes in children: the EURODIAB Study , 2001, Diabetologia.

[24]  A. Amos,et al.  The Rising Global Burden of Diabetes and its Complications: Estimates and Projections to the Year 2010 , 1997, Diabetic medicine : a journal of the British Diabetic Association.

[25]  D. Smith,et al.  Turkish honeybees: genetic variation and evidence for a fourth lineage of Apis mellifera mtDNA. , 2000, The Journal of heredity.

[26]  P. Zimmet,et al.  The Rising Global Burden of Diabetes and its Complications: Estimates and Projections to the Year 2010 , 1997, Diabetic medicine : a journal of the British Diabetic Association.

[27]  A. Al-Herbish,et al.  Prevalence of type 1 diabetes mellitus in Saudi Arabian children and adolescents. , 2008, Saudi medical journal.

[28]  N. Yordam,,et al.  The epidemiology of juvenile-onset insulin-dependent diabetes mellitus in Turkish children. A retrospective analysis of 477 cases. , 1994, The Turkish journal of pediatrics.

[29]  A. Hattersley,et al.  Definition, epidemiology and classification of diabetes in children and adolescents , 2009, Pediatric diabetes.

[30]  J. Tuomilehto,et al.  Sex difference in the incidence of insulin-dependent diabetes mellitus: an analysis of the recent epidemiological data. World Health Organization DIAMOND Project Group. , 1997, Diabetes/metabolism reviews.

[31]  H. Demirbilek,et al.  Incidence of Type 1 Diabetes Mellitus in Turkish Children from the Southeastern Region of the Country: A Regional Report , 2013, Journal of clinical research in pediatric endocrinology.

[32]  F. Bookstein,et al.  Morphometric Tools for Landmark Data: Geometry and Biology , 1999 .

[33]  C. Patterson,et al.  Epidemiology of childhood IDDM in Northern Ireland 1989–1994: Low incidence in areas with highest population density and most household crowding , 1996, Diabetologia.

[34]  F. Rohlf,et al.  tpsDig, version 2.10 , 2006 .

[35]  N. Abdella,et al.  Prevalence of Type 1 Diabetes among 6- to 18-Year-Old Kuwaiti Children , 2005, Medical Principles and Practice.

[36]  J. Tuomilehto,et al.  Low Incidence of Childhood IDDM in District of Novosibirsk (Russia) , 1992, Diabetes Care.

[37]  A. Kence,et al.  Allozyme variability in a central Anatolian honeybee (Apis mellifera L) population , 1995 .

[38]  M. Abduljabbar,et al.  Incidence trends of childhood type 1 diabetes in eastern Saudi Arabia. , 2010, Saudi medical journal.

[39]  J. Diniz‐Filho,et al.  Phylogeographical autocorrelation of phenotypic evolution in honey bees (Apis mellifera L.) , 1999, Heredity.

[40]  F. Rohlf,et al.  NTSYS-pc Numerical Taxonomy and Multivariate Analysis System, version 2.1: Owner manual , 1992 .

[41]  Martin Drauschke,et al.  Identification of Africanized honey bees through wing morphometrics: two fast and efficient procedures , 2008, Apidologie.

[42]  A. Green,et al.  Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005–20: a multicentre prospective registration study , 2009, The Lancet.

[43]  Andone Estonba,et al.  Both geometric morphometric and microsatellite data consistently support the differentiation of the Apis mellifera M evolutionary branch , 2011, Apidologie.

[44]  N. Waugh,et al.  Urban/rural and deprivational differences in incidence and clustering of childhood diabetes in Scotland. , 1992, International journal of epidemiology.

[45]  Stefan Fuchs,et al.  Reevaluation of honeybee (Apis mellifera) microtaxonomy: a geometric morphometric approach , 2011, Apidologie.

[46]  C. Cardwell,et al.  Higher incidence of childhood-onset type 1 diabetes mellitus in remote areas: a UK regional small-area analysis , 2006, Diabetologia.

[47]  R. Uibo,et al.  The geoepidemiology of type 1 diabetes. , 2010, Autoimmunity reviews.

[48]  C. Beaufort Incidence and trends of Childhood Type 1 diabetes worldwide 1990-1999 , 2006 .

[49]  P. Bingley,et al.  Rising incidence of insulin dependent diabetes in children aged under 5 years in the Oxford region: time trend analysis , 1997, BMJ.

[50]  A. Kence,et al.  Mitochondrial DNA variation in honey bee (Apis mellifera L.) populations from Turkey , 2006 .

[51]  Dana Dabelea,et al.  Incidence of diabetes in youth in the United States. , 2007, JAMA.

[52]  A. Bereket,et al.  Prevalence of type 1 diabetes mellitus in 6–18‐yr‐old school children living in Istanbul, Turkey , 2011, Pediatric diabetes.

[53]  J. Ilonen,et al.  A six‐fold gradient in the incidence of type 1 diabetes at the eastern border of Finland , 2005, Annals of medicine.

[54]  L. Molinari,et al.  Epidemiology of Type I diabetes mellitus in Switzerland: steep rise in incidence in under 5 year old children in the past decade , 2001, Diabetologia.

[55]  A. Green,et al.  Is childhood-onset Type I diabetes a wealth-related disease? An ecological analysis of European incidence rates , 2001, Diabetologia.

[56]  E. A. M. Gale,et al.  Spring harvest? Reflections on the rise of type 1 diabetes , 2005, Diabetologia.

[57]  H. David Sheets,et al.  Geometric morphometrics for biologists : a primer , 2004 .

[58]  Adam Tofilski,et al.  Using geometric morphometrics and standard morphometry to discriminate three honeybee subspecies , 2008, Apidologie.

[59]  H. Hall,et al.  Molecular characterization of Turkish honey bee populations (Apis mellifera) inferred from mitochondrial DNA RFLP and sequence results , 2009, Apidologie.

[60]  L. Nyström,et al.  Gender differences and temporal variation in the incidence of type 1 diabetes: results of 8012 cases in the nationwide Diabetes Incidence Study in Sweden 1983–2002 , 2008, Journal of internal medicine.

[61]  Xujing Wang,et al.  Increasing Incidence of Pediatric Type 1 Diabetes Mellitus in Southeastern Wisconsin: Relationship with Body Weight at Diagnosis , 2009, PloS one.

[62]  E. Love,et al.  Increasing incidence of type 1 diabetes in children aged 0-14 years in Harbin, China (1990-2000). , 2008, Primary care diabetes.

[63]  G. Dahlquist,et al.  Worldwide childhood type 1 diabetes incidence – what can we learn from epidemiology? , 2007, Pediatric diabetes.

[64]  Şükrü Hatun Çocukluk Çağında Diyabet , 2003 .

[65]  M. Drauschke,et al.  Morphometric and genetic changes in a population of Apis mellifera after 34 years of Africanization. , 2009, Genetics and molecular research : GMR.

[66]  J. Tuomilehto,et al.  Large incidence variation of Type I diabetes in central-southern Italy 1990–1995: lower risk in rural areas , 1999, Diabetologia.

[67]  H. Gençer,et al.  Morphometric characterization of Iranian (Apis mellifera meda), Central Anatolian (Apis mellifera anatoliaca) and Caucasian (Apis mellifera caucasica) honey bee populations , 2007 .

[68]  A. Kence,et al.  Genetic and morphometric variation in honeybee (Apis mellifera L.) populations of Turkey , 2000 .

[69]  O Hammer-Muntz,et al.  PAST: paleontological statistics software package for education and data analysis version 2.09 , 2001 .

[70]  S. Fuchs,et al.  Ecoclines in the Near East along 36° N latitude in Apis mellifera L. , 2000 .