Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition.
暂无分享,去创建一个
Mårten Fryknäs | Rolf Larsson | Mia Niklasson | Anna Segerman | Tobias Bergström | Frida Nyberg | Malin Jarvius | Caroline Haglund | Magnus Sundström | Malin Berglund | Bo Segerman | B. Segerman | B. Westermark | A. Segerman | M. Jarvius | Anna M. Westermark | C. Haglund | M. Gustafsson | R. Larsson | M. Fryknäs | Mia Niklasson | Göran Hesselager | Lene Uhrbom | Bengt Westermark | G. Hesselager | Mats Gustafsson | A. Hermansson | Yuan Xie | Ann Westermark | Demet Sönmez | Annika Hermansson | Marianne Kastemar | Zeinab Naimaie-Ali | Yuan Xie | L. Uhrbom | T. Bergström | M. Kastemar | M. Sundström | M. Berglund | Frida Nyberg | Demet Sönmez | Zeinab Naimaie-Ali | D. Sönmez | Tobias Bergström | Lene Uhrbom
[1] Se Hoon Kim,et al. Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma. , 2013, Cancer cell.
[2] J. D. de Groot,et al. Acquired Resistance to Anti-VEGF Therapy in Glioblastoma Is Associated with a Mesenchymal Transition , 2013, Clinical Cancer Research.
[3] Martin J Aryee,et al. Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts , 2009, Nature Genetics.
[4] Wai Leong Tam,et al. The epigenetics of epithelial-mesenchymal plasticity in cancer , 2013, Nature Medicine.
[5] R. Shamir,et al. Enhancer methylation dynamics contribute to cancer plasticity and patient mortality , 2016, Genome research.
[6] Chibo Hong,et al. DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors. , 2015, Cancer cell.
[7] J. Dick,et al. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell , 1997, Nature Medicine.
[8] Gary D Bader,et al. Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity , 2015, Proceedings of the National Academy of Sciences.
[9] E. Holland,et al. In vivo radiation response of proneural glioma characterized by protective p53 transcriptional program and proneural-mesenchymal shift , 2014, Proceedings of the National Academy of Sciences.
[10] Voichita D. Marinescu,et al. The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes , 2015, EBioMedicine.
[11] Alexander Brawanski,et al. CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. , 2007, Cancer research.
[12] K. Black,et al. Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma , 2006, Molecular Cancer.
[13] Tatsuya Ozawa,et al. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. , 2009, Cell stem cell.
[14] Shawn M. Gillespie,et al. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma , 2014, Science.
[15] V. Weaver,et al. STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma. , 2015, Cancer research.
[16] Mark W. Dewhirst,et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response , 2006, Nature.
[17] Hongye Liu,et al. Olig2-Regulated Lineage-Restricted Pathway Controls Replication Competence in Neural Stem Cells and Malignant Glioma , 2007, Neuron.
[18] S. Nelson,et al. Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA , 2014, Science.
[19] Yuan Qi,et al. Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA , IDH 1 , EGFR , and NF 1 Citation Verhaak , 2010 .
[20] Cynthia Hawkins,et al. Identification of a cancer stem cell in human brain tumors. , 2003, Cancer research.
[21] R. Mirimanoff,et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. , 2005, The New England journal of medicine.
[22] Mark Bernstein,et al. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. , 2009, Cell stem cell.
[23] R. Wilson,et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. , 2010, Cancer cell.
[24] Dimitris Anastassiou,et al. Human cancer cells express Slug-based epithelial-mesenchymal transition gene expression signature obtained in vivo , 2011, BMC Cancer.
[25] J. Rich,et al. Cancer stem cells in glioblastoma , 2015, Genes & development.
[26] N. Potter,et al. Genetic and Functional Diversity of Propagating Cells in Glioblastoma , 2014, Stem cell reports.
[27] Thomas D. Wu,et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. , 2006, Cancer cell.
[28] Debyani Chakravarty,et al. Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response , 2012, Proceedings of the National Academy of Sciences.
[29] R. Huang,et al. Epithelial-Mesenchymal Transitions in Development and Disease , 2009, Cell.
[30] Franziska Michor,et al. Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma. , 2014, Cancer cell.
[31] J. Uhm,et al. The transcriptional network for mesenchymal transformation of brain tumours , 2010 .
[32] V. P. Collins,et al. Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics , 2013, Proceedings of the National Academy of Sciences.
[33] Yuri Kotliarov,et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. , 2006, Cancer cell.
[34] R. Mirimanoff,et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. , 2005, The New England journal of medicine.
[35] J. Visvader,et al. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions , 2008, Nature Reviews Cancer.
[36] P. Benos,et al. Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3 , 2013, Proceedings of the National Academy of Sciences.